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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Transient Receptor Potent" (30 stories)

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Lysoway Therapeutics Announces Preclinical Data Supporting First-in-Class TRPML1 Agonist LW-1017 in Scientific Reports
Lead StoryBusiness Wireworld
Sep 14

Lysoway Therapeutics Announces Preclinical Data Supporting First-in-Class TRPML1 Agonist LW-1017 in Scientific Reports

<a href="https://news.google.com/rss/articles/CBMihgJBVV95cUxPUDV5UW5SdG1GU2JIRkNQX2tjc1hoY3BGMHNtMXRTcW85NUliMW1mNVZwSU4wYnoyNkdtZGFZTVJ1RHlwYU1mdk9nQ1EtQzZzN1BTWU5PVDluMEd5amtZYjZUQXBqZDYxTzdRUmE3ekRJYWpfNFp1ckN0aWt0emZvbEU5SnMxX1FDVUF2MFMxX2E2SFZhdlRsRXl4eFp3YlhfVXBHR0VTdFdiV2VOaUlpdngtWkNDMG9fX3dwS1FXeXV6ZlVfQjZZTFQ1WDd4RlloNXVLa3NxaDc3Q1cwTHZSTHcyeEZaYzZRUjF2TWpJcU43M0JRZ0RYUU5TSWtmdElKX09KcW5B?oc=5" target="_blank">Lysoway Therapeutics Announces Preclinical Data Supporting First-in-Class TRPML1 Agonist LW-1017 in Scientific Reports</a>  <font color="#6f6f6f">Business Wire</font>

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Search Results for "Transient Receptor Potent"

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29 stories displayed
Unveiling powerful synergies between plant compounds that dramatically reduce inflammation
EurekAlert! Science News Releasesworld

Unveiling powerful synergies between plant compounds that dramatically reduce inflammation

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE9nU0lFSkU5NWswUHFzSzFXVmxMRFBIYVVXZk51QVpSYWk3NC1WU1NESk5YQng5NlRpTXhLNGtWcmZpSGhnQ1g0dHF6bW83WlRTMkNxTGFUblRVR3ZK?oc=5" target="_blank">Unveiling powerful synergies between plant compounds that dramatically reduce inflammation</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

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Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1
Journal of Neurosciencetech

Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1

<a href="https://news.google.com/rss/articles/CBMiWEFVX3lxTE1semxYYmxnUDhBUnphTS1iZmpuWWQ3a3VuOGNLN3pMWGF0UndLUmhiRnc5bUc4dFFtd0dhUlQ5Si1NX0JBUGdMZE55elFTWk1PT3hEZWsxSXQ?oc=5" target="_blank">Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1</a>  <font color="#6f6f6f">Journal of Neuroscience</font>

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Mint, eucalyptus and chili compounds reveal powerful synergy against inflammation in immune cells
Medical Xpresstech

Mint, eucalyptus and chili compounds reveal powerful synergy against inflammation in immune cells

<a href="https://news.google.com/rss/articles/CBMiigFBVV95cUxPd3VfVWZfZDRWMTJHY2hneTdPdUxFQkxlc1ViV1p4Vl9WZGxzQVpoMDE0dW9kQWt0b01vcHhOcEtmcTZCSEFtU2tyNndKd1FwTEdKeDIwR3R4Q3pheTBwSE4xb19ZRVdsYWRjRzJENDlwRGd4MXlBa19iNUFvNHV0QmJfZ3NuUnQyZ2c?oc=5" target="_blank">Mint, eucalyptus and chili compounds reveal powerful synergy against inflammation in immune cells</a>  <font color="#6f6f6f">Medical Xpress</font>

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New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel
Naturegeneral

New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE85VUpFLUxjaWdfbTdKcnNuUWtSYlNvZkFUQjN4Y2UwdmxYa19LWWoyeVlyVUg2NEVfaHdBRVotNmNaRjFBMHI4Wlp2aDluYVRnSWJYd2hPTzBqeVBoYWVn?oc=5" target="_blank">New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel</a>  <font color="#6f6f6f">Nature</font>

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CBN vs CBD: Psychoactivity, sedation potential, and endocannabinoid system impact
Weedmapsgeneral

CBN vs CBD: Psychoactivity, sedation potential, and endocannabinoid system impact

<a href="https://news.google.com/rss/articles/CBMid0FVX3lxTFBpaWRjQmJTcm1mWGZoTEpHdlczS0NKYk9lcV9LdVhxX3B0bW5qak5Sa0ZaRHg5VkM2T0FFSk5oZXdsd2NmMGNVY1hKd2FDQlVXVlVHYmRuLTFiY0ZIS3ZMcTExc0VNdEJEQzNIaF9EQV92bXZtU3JB?oc=5" target="_blank">CBN vs CBD: Psychoactivity, sedation potential, and endocannabinoid system impact</a>  <font color="#6f6f6f">Weedmaps</font>

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Transient Receptor Potential Vanilloid Subtype 1: Potential Role in Infection, Susceptibility, Symptoms and Treatment of COVID-19
Frontiersgeneral

Transient Receptor Potential Vanilloid Subtype 1: Potential Role in Infection, Susceptibility, Symptoms and Treatment of COVID-19

<a href="https://news.google.com/rss/articles/CBMijAFBVV95cUxPU0RTVFlZX3R1NnBRRHFOMVNiVExOS1RpZDJpQVlMajVBSFhsWURLcVFyTUdBRGJxN29vU3dHOFJiOEFLQlNiTXByZlUxTXNudU1GOEFJaEdiSl9fZXRQX0ozWnlOcHNHRXI3bjFROGJWSTdyYXV2OGY5MW52Y0M3LXgyVjdJSUR1N09PaA?oc=5" target="_blank">Transient Receptor Potential Vanilloid Subtype 1: Potential Role in Infection, Susceptibility, Symptoms and Treatment of COVID-19</a>  <font color="#6f6f6f">Frontiers</font>

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Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association
PNASgeneral

Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFBzckJ2RHRtaHFfT0lqeGRKb2h0NXdEZU5CVUJXbkVJSW9vOUtCQVI4TjV0c1BQME8tclNkUTVpQm1TMkNkd051Qk1tbGktM3VEVkJhS2IzZWV0cHZu?oc=5" target="_blank">Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association</a>  <font color="#6f6f6f">PNAS</font>

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Potent and Selective Agonists of Human TRPM5
Evotecgeneral

Potent and Selective Agonists of Human TRPM5

<a href="https://news.google.com/rss/articles/CBMihgFBVV95cUxNcEEzX3p5YWtQUkxMVFhsVTEwemtLYkZycXpqSlhobXBNUHhUZlhPMFh3dENqV0NCRVdVWm5ISmJ3MS1nOTFrLWM4NWFiV1M5NGhqNVVoZE1iMTRmNFVybXMxa0xjSm5RU3JOYkNPMk9yMHVWV2VfbHJRV3EtQ1BNVGlRTEJIUQ?oc=5" target="_blank">Potent and Selective Agonists of Human TRPM5</a>  <font color="#6f6f6f">Evotec</font>

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Advances in TRP channel drug discovery: from target validation to clinical studies
Naturegeneral

Advances in TRP channel drug discovery: from target validation to clinical studies

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1rbjByWjVQVUtCTFNhUTA5YlhLRDdzYUdNY1RETkRvVXJuR2kwckNROGhLWDJDLXF3cC1UOTd2anU0b0FNeVprWThURVdxcXZpcjB1NlNVVVExYi15WkY0?oc=5" target="_blank">Advances in TRP channel drug discovery: from target validation to clinical studies</a>  <font color="#6f6f6f">Nature</font>

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GABA Potency at GABAA Receptors Found in Synaptic and Extrasynaptic Zones
Frontiersworld

GABA Potency at GABAA Receptors Found in Synaptic and Extrasynaptic Zones

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxOOHc2UENnUUFrdHh4M1UxWjRHQ2QzSXlTMm5LcC1paHh4RmNicTdleEhOWDJhemJBTkY3WWZpZ0hPblJLN21rSXVWY3ROel9xSHVZZGFPSDJXc1NfM0NDQmRrU1hIV2tUS3FScTJ2Wmc2VVZ2MjFUb3BybV9WVlBJTlpBcWhoQ25zeGFTY29aQlZzWVR3ckpLbTFYZVlXUQ?oc=5" target="_blank">GABA Potency at GABAA Receptors Found in Synaptic and Extrasynaptic Zones</a>  <font color="#6f6f6f">Frontiers</font>

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Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release
PNASgeneral

Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE9wLWZIMXJwOGpnVUdZOEZLUm5WODFTampYY2lGQ3NzMkoxcC1wU2J0X203OU1jZWtueHd4QnVIV0RUdzk1NTJkbUlsT3BWZ0NVbE50cVdvZVB2ZUxJ?oc=5" target="_blank">Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release</a>  <font color="#6f6f6f">PNAS</font>

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Lactate is a potent inhibitor of the capsaicin receptor TRPV1
Naturetech

Lactate is a potent inhibitor of the capsaicin receptor TRPV1

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE13MUlYemo2SG5kc04tWXFPMjJnU1I1cm4xbEJVWjQ3V2ZkT21FQjFwYzBLeXhWRW5HdWNuRFVhQXhRVTJ0eUdSeU1US2J0VHpGMVpN?oc=5" target="_blank">Lactate is a potent inhibitor of the capsaicin receptor TRPV1</a>  <font color="#6f6f6f">Nature</font>

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Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles | Communications Biology
Naturetech

Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles | Communications Biology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0xcEZqM2E3dDlJaDljQWNlT1BxWTQtMkE5NDVOOXYyR1dWNWhkbGZsaU50RW5iZVBGTV9UelMtZDBPQlA2NzBXZjFPbklqZGViZGNMRGFQMnIxbVpHUU1B?oc=5" target="_blank">Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles | Communications Biology</a>  <font color="#6f6f6f">Nature</font>

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Synthesis, high-throughput screening and pharmacological characterization of β–lactam derivatives as TRPM8 antagonists
Naturegeneral

Synthesis, high-throughput screening and pharmacological characterization of β–lactam derivatives as TRPM8 antagonists

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBZc1EtV1FmbDJIRWNnMDN5TnNuY19ORTFBMWxxTENnTHdoRTRlcVktX2prZ2RLN0gtQlVvQ2Q5NkVjV2FoQUpsWUc1dFdaTEpERnE0QXp0RVFYSmxFMFlj?oc=5" target="_blank">Synthesis, high-throughput screening and pharmacological characterization of β–lactam derivatives as TRPM8 antagonists</a>  <font color="#6f6f6f">Nature</font>

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Potent but transient immunosuppression of T-cells is a general feature of CD71
Natureworld

Potent but transient immunosuppression of T-cells is a general feature of CD71

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1mcDFtZ2otY21HYno0cVhTYTJjbi1WQnFycV8zbnB0OW0yX0FWSUpHRWhSTHF5R3U2emVmZmQ3U2tjRUlLS1NMeU1GX1lmdmdhNmQ1X19YNkFBNUJiTE9Z?oc=5" target="_blank">Potent but transient immunosuppression of T-cells is a general feature of CD71</a>  <font color="#6f6f6f">Nature</font>

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Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity
Naturegeneral

Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE45eXQxMlJmM0NncG5kUExnYU1XbW5LTWt0dTljbWw0MEx5MFpuYTl2akk4azhpUWg3UWtDVG5mY29pd0VpMjJWNFJBLTBJWXptNXhNd0txX0tHdk03Mklj?oc=5" target="_blank">Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity</a>  <font color="#6f6f6f">Nature</font>

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Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation
Naturegeneral

Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA3eDhyWWh0bTFURTViRElkZENxR1R3d2xVcTBDMHNTUTgwN3ROMEFsSkloUnAzTEdkX3BaNFc0RTZCeHA3dE9lMG4ybW9TYmpGUUFVbllMNWgtWHZadHl3?oc=5" target="_blank">Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation</a>  <font color="#6f6f6f">Nature</font>

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A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy
Naturegeneral

A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBQeFloVnhESEo5NTFwQWJDSktrMlFZRDFGanpvWGZwS3EwdGVOSmR5UjFvbUpoQy1seWZkc05pbTR1dkw5d2hDREEwdkZleFI1Wk9sYWxaZG9ZT2JYVWxr?oc=5" target="_blank">A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy</a>  <font color="#6f6f6f">Nature</font>

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A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor
Naturegeneral

A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE84cTRLd2NDN0hjTEZBYmh5TmtHNFB0YkxaQzA1VFJZdS05dlZZMjE4YW15N0JibEFlVzN0Z3NqTGtGa2JmdkNXSEtnbGJLTDhtdXItUmNydWlWN2RWMFJz?oc=5" target="_blank">A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor</a>  <font color="#6f6f6f">Nature</font>

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Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA
Naturegeneral

Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1lWmFlVU5GS3ZSSE5zNTVuT1BuOWtJdDRTd1hmQXZacHlqMlVmRWdSTjdCVmdTVEdaQnNBbjFxdjBOZG9YMFRqOVNCQTZfYm9ycXBMMVFQN2U0SUhRbWlv?oc=5" target="_blank">Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA</a>  <font color="#6f6f6f">Nature</font>

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Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure
PNASgeneral

Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE53MXdjUkVVN2EwSlpMMUZ5R002SzBxT1dZTnRPdGpkeEh0OVNkWjR5cDF2MHNzeTRMeURWWno2SE1icTVlUnJ3cjFnR3Q5Tk1idUlTaFU0VkFteDZ3?oc=5" target="_blank">Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure</a>  <font color="#6f6f6f">PNAS</font>

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Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies
Naturegeneral

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

<a href="https://news.google.com/rss/articles/CBMiUkFVX3lxTE01WkJ5Q3M3Zm1RRndtbmFjWHZWWVNpR1FQUUNja1BiaGkyR1ZWc3J3QmtSamtWRk1zdVFKb1RNaWJwaGZocUdZMFc2VXoxNG1wOVE?oc=5" target="_blank">Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies</a>  <font color="#6f6f6f">Nature</font>

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Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects
Naturegeneral

Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9lUjdmT3VCTGljR0tDQTFpNHFCSjJpYWZsUF95WWNIQWVJWkJ2NVRPZV9QNnZtYWVCeHBpZFpjNFYydkFQUC1LR0k4MlpKRXp2RXQxYmEyak1jaFY2eTdr?oc=5" target="_blank">Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects</a>  <font color="#6f6f6f">Nature</font>

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Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels
American Heart Association Journalsworld

Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE8wQkdUbFI3Z1F4MmxNTG9NX2VmdF82WGo2d3ota3EzaUNnX1B5SDI4SE1MOEFNX2pHakxJQWdTVEVvZ0pXOXQxQWtsblBrY3lCVjZBSTUtWGl6NnlPSzNoTWUycEUxZlQ4ZVE?oc=5" target="_blank">Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels</a>  <font color="#6f6f6f">American Heart Association Journals</font>

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New insights on potency assays from recent advances and discoveries in CAR T-cell therapy
Frontiersgeneral

New insights on potency assays from recent advances and discoveries in CAR T-cell therapy

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxNZ1poNUhoeFQ0ZWVIbHN5NGdFZE5QVW1ZLXRFVlhDOVM5UGJwekpvY09IUUhJRGstOEMtd05PSjY4dXFpckk4blgxZTM5RkVxTE1uaUkzemdxNXpjQVFmaENnT3BpU0N2b0gtNEVCTXBzdFQ3OEx3c2taM1p2UTFCUU9QeGgtWkVYbmNYZkpVNGZadw?oc=5" target="_blank">New insights on potency assays from recent advances and discoveries in CAR T-cell therapy</a>  <font color="#6f6f6f">Frontiers</font>

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The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways
Naturegeneral

The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE9UcUdibjNIWTBuTXA0dHNjTElRaFVpZVI2c0YwWDBmZHhzekpXODE4SXhwTDgtVkdhckc3b0xXb2JVRnE4Q2hGNWR3RmhocEdreGVn?oc=5" target="_blank">The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways</a>  <font color="#6f6f6f">Nature</font>

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Goldfinch Bio reports positive data from GFB-887 trial
Clinical Trials Arenageneral

Goldfinch Bio reports positive data from GFB-887 trial

<a href="https://news.google.com/rss/articles/CBMid0FVX3lxTFBOdk1aNjU0SzNZSWJCVXlEQXliYTBVejY2OHZGeVVHRlR1TXdfaVFhYm5zNDNPdWM4V19HczZDdlRFY2U2dkRrenpuUlJRT19zTWpsMVNCcmNVMUxRSnNDYV9wam9TZVFaNEh5MXZOLS1DajV4US0w?oc=5" target="_blank">Goldfinch Bio reports positive data from GFB-887 trial</a>  <font color="#6f6f6f">Clinical Trials Arena</font>

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Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering
Naturegeneral

Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1rekRmNHA4QUoxX05YTWtTWmpmZUZMSG1VcllWYWViLVFoaGhxMHNhTFNLTEhNOFFyMjlOWlpUcHN5VHYxQlhyRU9mOUhDWnlabnNrQ3FJRWtsZUNGWjlj?oc=5" target="_blank">Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering</a>  <font color="#6f6f6f">Nature</font>

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Enhancing the potency of in vivo lentiviral vector mediated gene therapy to hepatocytes
Naturegeneral

Enhancing the potency of in vivo lentiviral vector mediated gene therapy to hepatocytes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE01bEF0UHZpZ0JCSnkxMktQU3h1R0c3M01fWTlaTGZicmpfcXQ1SWdBNVNQVWJiZkxnd2ZTbWVxd2NsdS1CRDVrazdUeVY5a2toRDlGTmxBSTR3UnBNekNV?oc=5" target="_blank">Enhancing the potency of in vivo lentiviral vector mediated gene therapy to hepatocytes</a>  <font color="#6f6f6f">Nature</font>

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"Transient Receptor Potent" — Live Google News Trends & Headlines