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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Transcriptomic and phenot" (30 stories)

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Transcriptomic evidence of CD8⁺ T-cell exhaustion-like phenotype and mitochondrial impairment underlying immune dysregulation in feline chronic gingivostomatitis
Lead StoryNaturetech
May 6

Transcriptomic evidence of CD8⁺ T-cell exhaustion-like phenotype and mitochondrial impairment underlying immune dysregulation in feline chronic gingivostomatitis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBvYUk4eG9vQ0xaNEV4b2VGWGtCQmhMSzA3TlZvVndZdTZNQkMzdUhhcVpjdU8xVHExSkZTbjVyR1REYkR4TjFrMlBEbHlfWmNQQ3RQNnRBQXJKWDFrcENn?oc=5" target="_blank">Transcriptomic evidence of CD8⁺ T-cell exhaustion-like phenotype and mitochondrial impairment underlying immune dysregulation in feline chronic gingivostomatitis</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Transcriptomic and phenot"

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29 stories displayed
Systematic genotype–phenotype mapping and transcriptomic analyses highlight SEMA6A as a candidate for neuronal migration defects in 5q22–q23 deletions
Naturegeneral

Systematic genotype–phenotype mapping and transcriptomic analyses highlight SEMA6A as a candidate for neuronal migration defects in 5q22–q23 deletions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE04ZURRc3ZRak1WbjZqdUlKYnlGTFRjRHB2bnpWbjZhS3oxa3FsQVlWV2doUWJuNWJYY2xLOF92Q1ZiN0FiZGFiTlh5Vkt6bVZsTFZ6Z2ZHS2psMkdGdEc0?oc=5" target="_blank">Systematic genotype–phenotype mapping and transcriptomic analyses highlight SEMA6A as a candidate for neuronal migration defects in 5q22–q23 deletions</a>  <font color="#6f6f6f">Nature</font>

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Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes
Science | AAASgeneral

Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE1zdm9GM1dNUDRJNFZNM0JEajd0TXI2SGFvUEt5ZE9ubm40MnFlejJMeVVWNzMwXzZnRXpTbDdyVFgtLU1uanJibWpIQ0RjRWl2enVkVGVEd2E2X2dnSFY1Mw?oc=5" target="_blank">Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes</a>  <font color="#6f6f6f">Science | AAAS</font>

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Identifying transcriptomic signatures that mediate the causal effect of genotype on Alzheimer's disease
Frontiersgeneral

Identifying transcriptomic signatures that mediate the causal effect of genotype on Alzheimer's disease

<a href="https://news.google.com/rss/articles/CBMilAFBVV95cUxPX0NaWW1nRWpZRUhCdHNCOUcwUWZVMWdILWh4VEhhYl80VWVnS2pxUERoV3c2QUZRNWxxV0Q3QThNcExEajJtcWl5TUJfTGFuLVZLY1dRcjBPNnV6bnk4T0NGbjc1bnpsbHRVdTNGRVd4Mmk5QzgwaVhrNDgwVW5XTTJVUG9WZEt2TVdQeHEwRExVd1hK?oc=5" target="_blank">Identifying transcriptomic signatures that mediate the causal effect of genotype on Alzheimer's disease</a>  <font color="#6f6f6f">Frontiers</font>

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Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm
American Heart Association Journalsgeneral

Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE5HUlotcHlvV1c1dGpSTFlRT1RUWkM4MWg2MU1xdXUzZ2lJMmVDZkI3a3ZEejhPSkR4QXBqMndUd21NM2lSQ0dOWExaVkFUVC1WaFFKbmJrOUhla0l3MnF5b0Z3aHNTcXRyeFE?oc=5" target="_blank">Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm</a>  <font color="#6f6f6f">American Heart Association Journals</font>

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scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors
Science | AAASgeneral

scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1HZ0R3OEU3eXRvdzdZTTdHRVQyUHRCMHViS3VoMzB4MUE0MFlyTkdKXzJISjJXTHpSSVhDRkR2WXVtMXJCa1VFd3h3TEJRdmdOYUtEQ0pUQkF6ZTFWZ0ZR?oc=5" target="_blank">scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors</a>  <font color="#6f6f6f">Science | AAAS</font>

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Full length transcriptomic profiling reveals insights into the white coat phenotype in Waardenburg syndrome mice harboring the Mitf R324del mutation
Naturegeneral

Full length transcriptomic profiling reveals insights into the white coat phenotype in Waardenburg syndrome mice harboring the Mitf R324del mutation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1HSGZHcXZPV2p2Nk5xQ2NDOU94WGlEeVFrWTZVUVd2MEtNaGZIaHdrSVhqOHZLM19PSTVaLS1zTFhVXzU1bF82YmtreGZ3bVY4YV9NZkpydWhMZExwVXRz?oc=5" target="_blank">Full length transcriptomic profiling reveals insights into the white coat phenotype in Waardenburg syndrome mice harboring the Mitf R324del mutation</a>  <font color="#6f6f6f">Nature</font>

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A single-cell resolved genotype-phenotype map using genome-wide genetic and environmental perturbations
Naturegeneral

A single-cell resolved genotype-phenotype map using genome-wide genetic and environmental perturbations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5walZhMUpwdkY4WnVvR1pYWXhzZEhZbFlXVXUxcEI2cUxxODFGYmtPb3ZsczV5LS1Va1lVRjhRSWVRRGU0Q0tCb0J3bTBHak1uWVlYUHdBak0xZ2hQWmNV?oc=5" target="_blank">A single-cell resolved genotype-phenotype map using genome-wide genetic and environmental perturbations</a>  <font color="#6f6f6f">Nature</font>

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Transcriptomic and metabolomic analysis based on different aggressive pecking phenotype in duck
Naturegeneral

Transcriptomic and metabolomic analysis based on different aggressive pecking phenotype in duck

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5wcEotQjJMUmEtUEhwRmNZNnYxMnhSUHpPUVB3NEV0WndoY3g4SXVSMUR2RDNvdVltRUlZdm40V2FkVmt2U1RlbU9xMFVXaE9rQmo3OG1XSFFzYmxzVGJ3?oc=5" target="_blank">Transcriptomic and metabolomic analysis based on different aggressive pecking phenotype in duck</a>  <font color="#6f6f6f">Nature</font>

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Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state
Naturegeneral

Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAxb05qcEprMVlNV2lKck1sRWpORkVKMUtXa2g5dXkwNGlHdzdreVluY2xIRFBveTJ4NVM5eHZENkxqVjRlMUVYTlpXODR4YW5QUGhERFUwU0N2QmJWSVYw?oc=5" target="_blank">Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state</a>  <font color="#6f6f6f">Nature</font>

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Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships
Natureworld

Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1JTFdfQzFLMmt3dFg3YlpjVnlhS0FOdFVZX1IyUTYzNkE5b1VBVTRCSzFHSHM5d215UkljaDB2eEwydG5CUjUtVFpaQXUyS2V2NHhHNVFPUHlRR0xOMXlR?oc=5" target="_blank">Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships</a>  <font color="#6f6f6f">Nature</font>

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Phenomics and transcriptomic profiling of fruit development in distinct apple varieties
Naturetech

Phenomics and transcriptomic profiling of fruit development in distinct apple varieties

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1GcldpNmJYeGNFM2NRWkZnVVNSSWdwSVdnSUVYUzBZZ0VmMVRjdmtmMmpKcHY3MDgyTDM3LVlVUU93RkNnenJyMFlHcFZ0SWNpcnd0WnR3bHlGU25BRV9n?oc=5" target="_blank">Phenomics and transcriptomic profiling of fruit development in distinct apple varieties</a>  <font color="#6f6f6f">Nature</font>

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Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable prognosis
Natureworld

Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable prognosis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1iS1Y5WXFHdThrSWVaUjEzcWFxanFRalBKM01zS2RaamRSUTFBak01VXJRWmlfWllTaFctNjZXX19qOE5MNnpoSWUyUjY3VjZhejluUXB5OWlYSHRLaElJ?oc=5" target="_blank">Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable prognosis</a>  <font color="#6f6f6f">Nature</font>

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Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis
Naturegeneral

Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9ZTjNrdG9YN2xTakY0c1VWc2hveVhheklsa2Vld1JDVVk1U2ctMG4zYU9yZ0lHRzNPUjdDdmlraXVLTFNJc1FqU3hrbHZidXRkS25VTjBmM2c5S093c09N?oc=5" target="_blank">Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis</a>  <font color="#6f6f6f">Nature</font>

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Transcriptome-conditioned molecule generation via gene interaction-aware fragment modeling with a GPT-based architecture
Naturegeneral

Transcriptome-conditioned molecule generation via gene interaction-aware fragment modeling with a GPT-based architecture

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE50VDdQNVZfRWxCcTVObHdpSF9yclE2MFYwZ25XMVZFR1hINS1OX19uQkNwQ3RSTXBkWkpXTHJNOThzRXZ3R3VmRThOeXMyc2xBdEFUUkpaSUpPdWZpZnVr?oc=5" target="_blank">Transcriptome-conditioned molecule generation via gene interaction-aware fragment modeling with a GPT-based architecture</a>  <font color="#6f6f6f">Nature</font>

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Progressive changes in phenotype, transcriptome and proliferation capacity characterise continued maturation and migration of intestinal cDCs in homeostasis
Naturegeneral

Progressive changes in phenotype, transcriptome and proliferation capacity characterise continued maturation and migration of intestinal cDCs in homeostasis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE45NjJHVUpZdmlwZk9fa1U1V3Z5VTZYNDNiQlBNY29lM3U5ejI0UHdmdnhqZEJqNU5Gc0ctME1ZanJBb1dEWG43c0RsQVlZSThLdmxOUmhMY2pwZVJlVU1B?oc=5" target="_blank">Progressive changes in phenotype, transcriptome and proliferation capacity characterise continued maturation and migration of intestinal cDCs in homeostasis</a>  <font color="#6f6f6f">Nature</font>

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Adaptation of the Spalax galili transcriptome to hypoxia may underlie the complex phenotype featuring longevity and cancer resistance | npj Aging
Natureworld

Adaptation of the Spalax galili transcriptome to hypoxia may underlie the complex phenotype featuring longevity and cancer resistance | npj Aging

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA2d2JONmd0SzNjQ1k1U2I5cGg0d2VRTGJEeG9BdWtNUHBvNkRtRm9acHJiVnV5Q2JaWi1ZdkZlVjRUOElLY05fNlMyMzdlT3ZVU2NvcTMxWktDRVZMM3FJ?oc=5" target="_blank">Adaptation of the Spalax galili transcriptome to hypoxia may underlie the complex phenotype featuring longevity and cancer resistance | npj Aging</a>  <font color="#6f6f6f">Nature</font>

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Deep representation learning of chemical-induced transcriptional profile for phenotype-based drug discovery
Naturegeneral

Deep representation learning of chemical-induced transcriptional profile for phenotype-based drug discovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB2c0MzbVNYemZBSXpDdXJwdHNkLUM5SzJIc2JZVWxUYi1Ub3otTF9xSTg4VWFGano2d3RLbHZWcFU0cF8wSm84aWctTDJxQWlQS2NhVVJETVpENTFoWWtF?oc=5" target="_blank">Deep representation learning of chemical-induced transcriptional profile for phenotype-based drug discovery</a>  <font color="#6f6f6f">Nature</font>

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Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis
Naturegeneral

Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8xdTN3ME1MVWcxUXZyTlNrc2J5ZUUxMl9mdnQ1S0dYbmVseWJSUFFMaFN5SlVpN0U2NnZaWUhQX2Fud3NXUnAxcWtPYk1lcEdoTXV4Nm1qT3dTSXVEb0xj?oc=5" target="_blank">Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis</a>  <font color="#6f6f6f">Nature</font>

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Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes
Naturegeneral

Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1XeUlsd2FtcHloSU80U1piLU9KUWJxdHR5ZEktV0lMcnBLZ2tFc240X21Sa2FnLXlIT2l2c21iUjlyY0Q2Z2Q5Rm5DNDlKZGpxZFBvMTQ4LW5VeGtsa0Zj?oc=5" target="_blank">Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes</a>  <font color="#6f6f6f">Nature</font>

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The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics
Natureworld

The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBQemVON0U3VFZWWjlfcWY2U1YwVEdwYk9FQ3NBazROLWNXNUtrNXowS2RSU3dRQU51N1VUc0lGTE9RYVlXWVBFa0l0Ul96Zkk1U2VBS3pjSGw1R0VMckJn?oc=5" target="_blank">The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics</a>  <font color="#6f6f6f">Nature</font>

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A consensus blood transcriptomic framework for sepsis
Naturegeneral

A consensus blood transcriptomic framework for sepsis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBOdDZKdllpcTBBTWRhaWVVNW5BdnFFMVVhb1ZfcnlWdUkwRDAxUXFMYzdGdEV2MWxrd25xai1BNlVrYUxjWERTSW9fLUF5a2ZzRzhhQ3ZNT1hHcEZPVklr?oc=5" target="_blank">A consensus blood transcriptomic framework for sepsis</a>  <font color="#6f6f6f">Nature</font>

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Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup
Naturegeneral

Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9oTTJUR3ZaLXhJSGlxSVZnVzJSclQ4N2tTcTkwZEFRNEYwRjU0OFBQYS1MZF85SFllSU1iTXRQVGQ4NU1BT0VCd2EtYTBBXzFsMnFhNkwwYk5wNnlENzN3?oc=5" target="_blank">Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup</a>  <font color="#6f6f6f">Nature</font>

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Evolutionarily informed machine learning enhances the power of predictive gene-to-phenotype relationships
Naturegeneral

Evolutionarily informed machine learning enhances the power of predictive gene-to-phenotype relationships

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPUEVmLVg4MzNuRkpuTno1UkFHTTFXYTlySWR1UjcyYWp3eEQ1M090eTM0ZG9pZXZnV1h0eFNXVTBPenVSZm9fS1IzS09vTHp0UTBGNGhnS3JrT1BGNHpn?oc=5" target="_blank">Evolutionarily informed machine learning enhances the power of predictive gene-to-phenotype relationships</a>  <font color="#6f6f6f">Nature</font>

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Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models
Natureworld

Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1wLUlZbm5YalZZVWFTRC1ielFIQWxHb2F5QVdiemozbXI1Sk1NS2plck1WemxkdFZEazZQZ2hUM09XUUJaRndJdjVHbDhwSHJDY25GX1VFWU1QdDRpeHF3?oc=5" target="_blank">Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models</a>  <font color="#6f6f6f">Nature</font>

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What is the Connection Between Genotype and Phenotype?
UC Davis College of Biological Sciencesgeneral

What is the Connection Between Genotype and Phenotype?

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE1QTUVGQUZscm1UNjNoT0xFR2doTmZnWFJlbmVYX1lkVEpzSnR0emoxT3hpSXV0TkdRWHpkTUxQZi1TRXpDdGdENl91dGlCa3UxUVBER0RQSDFXS3ZLdnZTdA?oc=5" target="_blank">What is the Connection Between Genotype and Phenotype?</a>  <font color="#6f6f6f">UC Davis College of Biological Sciences</font>

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Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia
Naturegeneral

Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBfSGdfTUJvOHhLbEJnSWxaWDNGR20tZVRIaTJzQWJTUWJJM2FUa2JZQkdKTHptNUNNSlZnaDN6Qll2dzNzd19lYlNkckgycWNmYW5INVhCRE0yUEYwZVVB?oc=5" target="_blank">Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia</a>  <font color="#6f6f6f">Nature</font>

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Integrated single-cell transcriptomic atlas of human gastric and colorectal tissues across diverse phenotypes
Naturegeneral

Integrated single-cell transcriptomic atlas of human gastric and colorectal tissues across diverse phenotypes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9VODVRb3E4YmFHLVVDYVBvWHpJa0JTWGotUWhkQU1QMkpHYjFzbl8xR3FadmZxSXotNjBQdjRRMEF1T1JLTTdtX0dEb19TTzhnbWdaVU9JRHR1MnZqZ3pB?oc=5" target="_blank">Integrated single-cell transcriptomic atlas of human gastric and colorectal tissues across diverse phenotypes</a>  <font color="#6f6f6f">Nature</font>

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Pheno-RNA, a method to associate genes with a specific phenotype, identifies genes linked to cellular transformation
PNASgeneral

Pheno-RNA, a method to associate genes with a specific phenotype, identifies genes linked to cellular transformation

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFBrbWluSWJrZzlMY2lGTUlYX0NwQzdVR0UzVlNPRU51bl9SMVRlRFhHMkp4LUxUVFM5dXdUb01pbndZZmwxOFlfdGwyR1JkLVN0eDN5QTBEeFBtbjl1?oc=5" target="_blank">Pheno-RNA, a method to associate genes with a specific phenotype, identifies genes linked to cellular transformation</a>  <font color="#6f6f6f">PNAS</font>

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High-throughput mechanical phenotyping and transcriptomics of single cells
Naturegeneral

High-throughput mechanical phenotyping and transcriptomics of single cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1fWVFuUDcxenctYldNVk1PZGttTXVzbGlCUU5FeWVuM2x2WUpjOFEyMk96d2N4bG9XOXJyd2pFX2tXdHdFOHIxLU5QWjZKZHI1aXlFRHJQQkpfSEpwbEo0?oc=5" target="_blank">High-throughput mechanical phenotyping and transcriptomics of single cells</a>  <font color="#6f6f6f">Nature</font>

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