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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "The targeted overexpressi" (30 stories)

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Targeting oxidative stress and mitochondrial dysfunction via URG7 overexpression in an in vitro Parkinson’s disease neuronal model
Lead StoryNatureworld
Feb 19

Targeting oxidative stress and mitochondrial dysfunction via URG7 overexpression in an in vitro Parkinson’s disease neuronal model

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9ZRVJ0dTZLOHExUlFJbWFocTVGall0NHI0bEVET2xsT3V1UkdfTDRacHRrTGVVZDZRYzRMY2dEMll2Z1RnM2NWbHR3ZE5wQzJaWnJjX1NMTjdBdWgxRE5n?oc=5" target="_blank">Targeting oxidative stress and mitochondrial dysfunction via URG7 overexpression in an in vitro Parkinson’s disease neuronal model</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "The targeted overexpressi"

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29 stories displayed
B7-H3 and GD2 overexpression as immunotherapeutic targets in retinoblastoma
Natureworld

B7-H3 and GD2 overexpression as immunotherapeutic targets in retinoblastoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9NR3llVkdRWkUzLXd5Q3dWYUs1WWNfdUpHS0pUZk9BVE15Q2pEV2htTGZucV9FWk01ZkZhcllHVUppY0djcVVQZ1hQOUtBT1cxQlpmMlY3LVNOTVZNWlB3?oc=5" target="_blank">B7-H3 and GD2 overexpression as immunotherapeutic targets in retinoblastoma</a>  <font color="#6f6f6f">Nature</font>

Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
Science | AAASgeneral

Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTFB1UkRXSGJrNXJ2SmIxODJITy16TVBicFVXUDJUczVFZXBlQWI2VWJKTk1vNEdxWF9wRkdGRThVRFZNdTR6RlRyemF2Z1kxaWR5MDZkMTVrejA3b1BUakkzZA?oc=5" target="_blank">Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria</a>  <font color="#6f6f6f">Science | AAAS</font>

Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function
PNASworld

Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function

<a href="https://news.google.com/rss/articles/CBMiW0FVX3lxTE5DamwxRk5OaEpvUlV0cEh1QTNnbG5BMnFodl9WdDV2c1dJd0tIcnFiMTlMZlVFWW5ob0lwNHdkM1hjdktfb3BlMTdtcTU0UHBfclEwNmxCbmVKdHM?oc=5" target="_blank">Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function</a>  <font color="#6f6f6f">PNAS</font>

Down syndrome and DYRK1A overexpression: relationships and future therapeutic directions
Frontiersgeneral

Down syndrome and DYRK1A overexpression: relationships and future therapeutic directions

<a href="https://news.google.com/rss/articles/CBMiogFBVV95cUxNQXlZMzJremJDLU4yQUxRdURXS1NWOF9sWlYwRzgxYkZzSUhvZ3BqZnZkSGs1WkRIR3B4VFFJYUVrUkdFSW05aWlqMGhyem1RV19TcE83RTdfUnBIUzItTnpYZm9CamRXaVVROTJwdENrUFFrNXo2WUZtaWRkdzFncVQwUWRCZFNwd3o2UG9NSk1YN2xIRUd1YU51enJYdWYwVUE?oc=5" target="_blank">Down syndrome and DYRK1A overexpression: relationships and future therapeutic directions</a>  <font color="#6f6f6f">Frontiers</font>

CD200 Overexpression in Acute Myeloid Leukemia: A Potential Target
Hematology Advisorgeneral

CD200 Overexpression in Acute Myeloid Leukemia: A Potential Target

<a href="https://news.google.com/rss/articles/CBMipAFBVV95cUxOWTJpX1d2eW5oa3VRQzhHeDJXRkZkdndqVGNZUjVLNk1UT1NSVEFlOWNtQU80eFpJYTJVYjJOMUM3RFhnZWtDMk5HcjVmV3pCNDN5TFlVUjcxVm9CTXlnbzBET3RWVnhpUGZXZXltNEU4dFJZTkpKbTRTLUZycDEyOHktVnIzZDg5SlM2anlTUUtlaHlUTlg1WkNNX2I5azIxS0xpYQ?oc=5" target="_blank">CD200 Overexpression in Acute Myeloid Leukemia: A Potential Target</a>  <font color="#6f6f6f">Hematology Advisor</font>

The targeted overexpression of SlCDF4 in the fruit enhances tomato size and yield involving gibberellin signalling
Naturegeneral

The targeted overexpression of SlCDF4 in the fruit enhances tomato size and yield involving gibberellin signalling

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5qMy1Hc1Vid1F3S0lfN0hzbU52aGRPTjVUN3FkY1ppNGRZS0dNZHRPYk41T25Jd2hGSGxlRGJEWUhhTjVGaml4cllvZmRXMTlrajVSNjZsTlhOWUpleHc0?oc=5" target="_blank">The targeted overexpression of SlCDF4 in the fruit enhances tomato size and yield involving gibberellin signalling</a>  <font color="#6f6f6f">Nature</font>

Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression
Frontiersgeneral

Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression

<a href="https://news.google.com/rss/articles/CBMioAFBVV95cUxNSFRDVXBGTHFueUVHWk4yUzZyY1VxVGc3MGVhT3gxbUZmVjFJcm9jeG9pLU9WN1F6WkxncW9GQkgxRXJLRktQOFNNM3RldG9pRjk2Qm1vUG0zck93enIwdzZvUTlPSlNOUWlqNVZkREt6NHEtX1hJUUJ0MXhxUXNCSXVhdUZBVEVOSUItTVpRMmMwNnhSMmdRRnlEN2R0dVpF?oc=5" target="_blank">Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression</a>  <font color="#6f6f6f">Frontiers</font>

Opposing effects of target overexpression reveal drug mechanisms
Naturegeneral

Opposing effects of target overexpression reveal drug mechanisms

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE1pclZxWEZKNlVlR0Z0YlpTRDdVeDhLYlRGMlZGX3IyR0ZzTlp6VVFtV2R2WlZOQXdXTGFPQWN5aG5zaEVUNXhiSHdRUGhkcDNiZm9zTg?oc=5" target="_blank">Opposing effects of target overexpression reveal drug mechanisms</a>  <font color="#6f6f6f">Nature</font>

Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle
Naturegeneral

Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE90NVlTSklRTmRGZHJYQ3lkSnFEM3lnNmpJTG8zVDNSNGZTNGVUMU5jM2lMLUVGZFNJQ0ZhcXBYNjlEb04zSWZqS2hraTZoTlJiM0JaWWZMRDlSc3ZWRFZn?oc=5" target="_blank">Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle</a>  <font color="#6f6f6f">Nature</font>

miR-326 overexpression inhibits colorectal cancer cell growth and proteasome activity by targeting PNO1: unveiling a novel therapeutic intervention strategy
Natureworld

miR-326 overexpression inhibits colorectal cancer cell growth and proteasome activity by targeting PNO1: unveiling a novel therapeutic intervention strategy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB3RmxndG5hWUZBdkV4NVB6WjFlWjFoOVAtNzRYVWluQjJhR0pJdkl1UXl1eUFYbW82eHdGOV9Rc0E1WXUxWjJlTmdVamtVQ0dJLV85U2tqTVRLdkltT0lF?oc=5" target="_blank">miR-326 overexpression inhibits colorectal cancer cell growth and proteasome activity by targeting PNO1: unveiling a novel therapeutic intervention strategy</a>  <font color="#6f6f6f">Nature</font>

Copy-number amplification drives IFI30 overexpression and coordinated immune activation, identifying a novel diagnostic and therapeutic target in gastric adenocarcinoma
Natureworld

Copy-number amplification drives IFI30 overexpression and coordinated immune activation, identifying a novel diagnostic and therapeutic target in gastric adenocarcinoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1NM0FzcnFlUWZ1aE9NWWdvSlkwMVRkSFRpMTZaTFZscF84c1Y0dTRWZmpxcTN3S3czcUJLU0haMjVXTGRYbTRGZTVqaEdNdGV4VkdiOHZOV1FrLWh4M1k4?oc=5" target="_blank">Copy-number amplification drives IFI30 overexpression and coordinated immune activation, identifying a novel diagnostic and therapeutic target in gastric adenocarcinoma</a>  <font color="#6f6f6f">Nature</font>

Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis
Naturegeneral

Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1JUm9zZFpuQTdtZHZ0X3ZYUHlOMThnbExWMUp4WjNRR2o3OGxlUmJhSXNtUjk1YnpEb1FzMXJfOGg3ZFIzZ1UxUWExaFpJVjFYZFFqNzRRbjhPZDNTdlo4?oc=5" target="_blank">Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis</a>  <font color="#6f6f6f">Nature</font>

SPP1 overexpression is associated with poor outcomes in ALK fusion lung cancer patients without receiving targeted therapy | Scientific Reports
Natureworld

SPP1 overexpression is associated with poor outcomes in ALK fusion lung cancer patients without receiving targeted therapy | Scientific Reports

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5SOFVnT0oxbkdZVVAyOW14dVg5QUFaZE83QXBCUHFJaWxzMmFobWtFWnA0cjV4aXhwX1lBUkxHXzBrd21NT2xlY3k4akJyMk9kbEJSRnFOUGs4bXRoZGd3?oc=5" target="_blank">SPP1 overexpression is associated with poor outcomes in ALK fusion lung cancer patients without receiving targeted therapy | Scientific Reports</a>  <font color="#6f6f6f">Nature</font>

Targeting AXL and RAGE to prevent geminin overexpression-induced triple-negative breast cancer metastasis
Naturegeneral

Targeting AXL and RAGE to prevent geminin overexpression-induced triple-negative breast cancer metastasis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5iRVd0anVXWGZBc2dZdktyanFpTGlmYWROTXFxNTVqaHBtX2FtUTB5NjZyMnJ6Tl8zV21jRHprN0tZNS1TSExaWmJjMzJDT2Y3bEMxdms1bW5mMzhHVEtZ?oc=5" target="_blank">Targeting AXL and RAGE to prevent geminin overexpression-induced triple-negative breast cancer metastasis</a>  <font color="#6f6f6f">Nature</font>

ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy
Naturegeneral

ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBOQV9NMHAyQWJwZXhpckd3SktGT3E4MVlYeFlvSk9wR09BcWdWTmY1bGU1T0Y4cDhvWXp1c0FBSmZrNFJzWE5jMnRZM3hsWTN1cXZQNXVJLWJWem5nVFQ0?oc=5" target="_blank">ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy</a>  <font color="#6f6f6f">Nature</font>

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells
Naturegeneral

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9BYW5BQUZaV0xSSlRJY0luTDNkc1lZMVFLX1pFMWV3SlZJd3FJUm0xeFRvaWlIMmJxOTIzQ2VwQXdObzI1OHZaS2RCTVpLcjZrcFBQTlh0SHNRYy0yWk1R?oc=5" target="_blank">Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells</a>  <font color="#6f6f6f">Nature</font>

Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney
Naturegeneral

Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE03NktNcHc5b3dQamF0dkJJOWw0ODFlZWhlUi13eENtLU1YMXBXM0sxam5iMXdBZFJKX1RvZFZOU1JuelM2NmZxNVNQTDdmeU9ta1MwVzBQcWFsNzlXU24w?oc=5" target="_blank">Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney</a>  <font color="#6f6f6f">Nature</font>

Preclinical efficacy of targeting epigenetic mechanisms in AML with 3q26 lesions and EVI1 overexpression | Leukemia
Naturegeneral

Preclinical efficacy of targeting epigenetic mechanisms in AML with 3q26 lesions and EVI1 overexpression | Leukemia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPTHVMdUpOS3BnSjhiVUw4bW5TdzNLeFdkeEs1SWt0Q014VWtEQnhMN0d5MEtyZkNaamFBcXhWUjBZS3BMcXo1R21yb055NzN5ampReTlSNGVCeUxJSHBJ?oc=5" target="_blank">Preclinical efficacy of targeting epigenetic mechanisms in AML with 3q26 lesions and EVI1 overexpression | Leukemia</a>  <font color="#6f6f6f">Nature</font>

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A
Naturegeneral

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1yRFQtOTFpd2FrQkh6Zm42MWR1QmRibHBXV3BrR3hDbkdGalRnNXNNbXQ0c0MtMFdsUXpHTnEzSVhfdTcwUDJTVzdlLTkyREwtNno2LXNQb3JGU2pNS180?oc=5" target="_blank">Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A</a>  <font color="#6f6f6f">Nature</font>

Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion
Naturetech

Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE95OWZYYTBfbndETnlmRU1Rd0d1OS16Z0R0bnRYY1VVZjJuYXU3X1R0bTdpNWdYMTlMazhVRldmVFcwN09DSThjSXZZSnh1STJiRXFUNUYxNXNLYnQwcXBV?oc=5" target="_blank">Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion</a>  <font color="#6f6f6f">Nature</font>

Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair
Naturetech

Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB3bExadmlSYXdlaGo3S2JQTDZidlEyX0h0dVc4UjV3RWJYbmVIaFF4QjlaZzFpWTRWX2loc2o0bWJ0NlFXNy1vMEF6T0xzYkR5RkpKVjBSdWhHNjlJUy04?oc=5" target="_blank">Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair</a>  <font color="#6f6f6f">Nature</font>

Overexpression miR-125a-5p inhibits HSCs activation and alleviates liver fibrosis through TGF-β/Smad2/3 signaling pathway and autophagy
Naturegeneral

Overexpression miR-125a-5p inhibits HSCs activation and alleviates liver fibrosis through TGF-β/Smad2/3 signaling pathway and autophagy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBWZ2YtYWFYdnZvQ0w4MGJycGR3WHpEUlVSSmJiNzFTQXlGYkFjbE5xcWd6ci1kbVFPNmZQb3VBQ2F5cjY1VjgyMVhQNnEzVTBGVE9TckZzd3otSHVNdUg0?oc=5" target="_blank">Overexpression miR-125a-5p inhibits HSCs activation and alleviates liver fibrosis through TGF-β/Smad2/3 signaling pathway and autophagy</a>  <font color="#6f6f6f">Nature</font>

Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model
Naturegeneral

Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE04OEh3aE9pUnRIb1ZIZDZoaUJobVptOTRTLU9YdmNWclAxWVlxZi1fdkIxQUtLTmtDTEUtUkZRZVdsdUxKMzROcDMtY1JHWnZiWmRtRTlPQzFkY195UWM0?oc=5" target="_blank">Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model</a>  <font color="#6f6f6f">Nature</font>

Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma
Naturegeneral

Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBranlUSUo2YjRGU2xjVHVERWxEbnNJRk1JN1hLV3RFU0Mza21uZjZUeDBuZTdmcGVZWWJ2amVITlRhVHI5X0pLSHBjUU1HMF8xM0pTT3EtZTBkcTkzYVRN?oc=5" target="_blank">Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma</a>  <font color="#6f6f6f">Nature</font>

In vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay)
Naturegeneral

In vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay)

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBKZXJjQm5lSTdHZml4TW5lUUxjbU1ycTVGXy1ob3hFcGpGam85WUhvMnMxaFZmcWx5VGF2UnEwbmhPWk5UbWpuYU9QUmF1SHJzdnBvV0JFRW9CbmhkaERZ?oc=5" target="_blank">In vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay)</a>  <font color="#6f6f6f">Nature</font>

PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer
Natureworld

PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTFBqQ1o1Vkp1cnhhNFZkd1ktVHkzamdlaG8zVGs1UGpZMXRHRmFwVWl6NGJyVFM2MkhGLXZkbnVuQWZnZDB3RVNvVDlsXzg1YjhVWkFN?oc=5" target="_blank">PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer</a>  <font color="#6f6f6f">Nature</font>

Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma
Naturegeneral

Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1jYzEtRUk5ajNDS2M5aVFXWFRSTWpDVG4wMEpvNVVQc2pJazlkOWJEcDdQZDRPVjBPZWdxWVlJcnRlSU9Hd3JWeHFvWGdQUVZjOXJRdmNRclFQM2Y3SEFR?oc=5" target="_blank">Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma</a>  <font color="#6f6f6f">Nature</font>

Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression
Naturegeneral

Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5wNkh4bk9nbjZaRFN6aDNQRzB2cEFyRVNuLVNkRi1ZcWZjZ1RIUUpVZU1QakVqNmlqM2h3QkJxWFcwQk1PUF80Y0JYSGN0YmwxNFM3UGt3b3kyb3l5NGZZ?oc=5" target="_blank">Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression</a>  <font color="#6f6f6f">Nature</font>

DNMT3B overexpression downregulates genes with CpG islands, common motifs, and transcription factor binding sites that interact with DNMT3B
Naturegeneral

DNMT3B overexpression downregulates genes with CpG islands, common motifs, and transcription factor binding sites that interact with DNMT3B

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE13QlBxaWUtLTNVU0YtZ2lfWDRQWnZqS0dxdFl6NndPTHFDZlNEVlZ4VjRzMWdjU1VnLWYxVnREclhvWDcxZTRzbklvVV9CcFVBNTJHdk0yTEllUnlDM3pn?oc=5" target="_blank">DNMT3B overexpression downregulates genes with CpG islands, common motifs, and transcription factor binding sites that interact with DNMT3B</a>  <font color="#6f6f6f">Nature</font>

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