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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "The mutational constraint" (30 stories)

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Mutational constraints on RSV F and its neutralization by antibodies
Lead StoryNaturetech
Sep 16

Mutational constraints on RSV F and its neutralization by antibodies

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAxRnBIbHJTUTNUdmlFVXFZU0NoRXJiRDFJNHJnM0dNN3NXN1RlVFhFRHFkd0hlMG1nYTFra25lcjJWMVU2XzlBZU8zTm91N2d0bHpLZ1Y1N0pNNk5UMjBz?oc=5" target="_blank">Mutational constraints on RSV F and its neutralization by antibodies</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "The mutational constraint"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
Constrained RNA polymerase mutational pathways distinguish corallopyronin A resistance from rifampicin resistance in staphylococci
Naturetech

Constrained RNA polymerase mutational pathways distinguish corallopyronin A resistance from rifampicin resistance in staphylococci

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1EVHdUVVFneVVRQ2Jpb0xaaExvbHRLNFpCamtpMTJfRmhmYXFwUG1SOFlnbkY2QWw2Ync4R3FVekh3Xzh0ZDYyVGdlMl9qREVUM2JuV3ZZQVpqdTlVSUZn?oc=5" target="_blank">Constrained RNA polymerase mutational pathways distinguish corallopyronin A resistance from rifampicin resistance in staphylococci</a>  <font color="#6f6f6f">Nature</font>

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Comparative analysis of advanced constraint-handling in quantum PSO with differential mutation for optimal power flow
Naturetech

Comparative analysis of advanced constraint-handling in quantum PSO with differential mutation for optimal power flow

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9uOGZsbGtHdWt1cS1KNmhHR3hfM3dzeHc4SVF6UWxEWnBlbmUzcC1nRkJMY01MWHE1LWNVR0JwMXlqc1VFTlpIT3FReTFaUU5vamI2cmFBU3E4TlVNTl9J?oc=5" target="_blank">Comparative analysis of advanced constraint-handling in quantum PSO with differential mutation for optimal power flow</a>  <font color="#6f6f6f">Nature</font>

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Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents
PNAStech

Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1oSVFES2RrLWQySEhDZHJJV3htcFVOR1U3WVJYbnJjeVROb0ptY1h2Q3NhN21MWXNITVhieVIzWkxVWGtYM3MwUE9uc0lxNVFKWEV0T2EweHdQNlE1?oc=5" target="_blank">Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents</a>  <font color="#6f6f6f">PNAS</font>

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The mutational constraint spectrum quantified from variation in 141,456 humans
Naturetech

The mutational constraint spectrum quantified from variation in 141,456 humans

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTFBQVVVKaGg4TTkxQVgtZHdPYjQ1TmR6eXktcVl4MHA5c1VqSjd3ZWpxRm12LWIzMF9nWG1NckZOSlMzdnBSYXJOU0lGeUNHNFg5Smp0cGpMd3FZVnpkVHc?oc=5" target="_blank">The mutational constraint spectrum quantified from variation in 141,456 humans</a>  <font color="#6f6f6f">Nature</font>

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A genomic mutational constraint map using variation in 76,156 human genomes
Naturetech

A genomic mutational constraint map using variation in 76,156 human genomes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5EWFp2X3BMQXg2VjVtaFNpalE3SEh2QU1TdE4xQy1ya0xmNFlQSmpVakZGbl9nSE16Q3BseFFIem9KOW5xUjd0azE1U2xxSUNpMDVmTi1FUU9rTmJQVG5r?oc=5" target="_blank">A genomic mutational constraint map using variation in 76,156 human genomes</a>  <font color="#6f6f6f">Nature</font>

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Regional nonsense constraint offers biological and clinical insights into genetic disease
Naturetech

Regional nonsense constraint offers biological and clinical insights into genetic disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5NaS1NS1FPTnU1Ty1iXzNwWU9MUVdwTTF6eVFkU2p5RXQyRUNmUkNfZFlMZnlkUXpjV0ZocENwVEgxSEpwYjhGaFhseW9PTU5GcVprQjByWERoODJwTTZv?oc=5" target="_blank">Regional nonsense constraint offers biological and clinical insights into genetic disease</a>  <font color="#6f6f6f">Nature</font>

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Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans
Naturetech

Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE05YUh3N19HbjFYUnRWZ3NRc2xPOThYalBTQmp5UXJYbGQzcjM2V3dEdGF1S3ZDcFdvQ1FDb0hzQzJQMThRLVNLWDVWNlhGbWhpcUZqQ2trRTFmaUJRa0ZN?oc=5" target="_blank">Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans</a>  <font color="#6f6f6f">Nature</font>

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Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets
Natureworld

Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFByamVQTGV1S3dRQkwtY0EzRGFZNWV3Y3doUnI4VktiM1hNOWRZa3o1OVVKeUFoSlNLMVFiZ0lkb0c3TlhGSi1zVmx0NmdLZUxqazRkWXl0X0UwbFQtcF9N?oc=5" target="_blank">Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets</a>  <font color="#6f6f6f">Nature</font>

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The 3D mutational constraint on amino acid sites in the human proteome
Naturetech

The 3D mutational constraint on amino acid sites in the human proteome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1Xank3SDNZM1BoQXAwR2c1UWVqd2NLTHdZemRRTEVBUE9GNWdxeU5FRzZyNnNaNlpZWkZRM2JtbFdlVHBaSGhVOXU5V21IekxYdVQxQTg1eTV6Qm1BeXE4?oc=5" target="_blank">The 3D mutational constraint on amino acid sites in the human proteome</a>  <font color="#6f6f6f">Nature</font>

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Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics
Naturetech

Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5YVVVTMHpmZG9OVEoxSDJMQWhFZmkwTnFTS0N6QTRtTXk1Rmc4cGoxMnJjN0lEUDhXLXBjVXowUG05dlNLbVloa1RtOUgwT3JYOE41b0pRQlQ5bWMyN3I0?oc=5" target="_blank">Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics</a>  <font color="#6f6f6f">Nature</font>

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A spectrum of nonsense-mediated mRNA decay efficiency along the degree of mutational constraint
Naturetech

A spectrum of nonsense-mediated mRNA decay efficiency along the degree of mutational constraint

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1uaUkyMVRuNUpoXzlhREZ3bHlyYmwyM0ZOZTZPQUVhdVN5YzB3YVI3Z3RicVdXWmN2VloyWFpvTGRBcGZQTjRpZzY5c18zM3V0ZUVmb1hMM2o3SjZleGlz?oc=5" target="_blank">A spectrum of nonsense-mediated mRNA decay efficiency along the degree of mutational constraint</a>  <font color="#6f6f6f">Nature</font>

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Interpreting short tandem repeat variations in humans using mutational constraint
Naturetech

Interpreting short tandem repeat variations in humans using mutational constraint

<a href="https://news.google.com/rss/articles/CBMiUEFVX3lxTE1aenhnNWs3bnFUVFpFX1BEV3c3NnJuU05CbWJpWW9jTnZLQm5XZzZsQzFrUUlPOHJ1ZmFvX2lZSFk0Z0JvYW1PRXR1WU93TElF?oc=5" target="_blank">Interpreting short tandem repeat variations in humans using mutational constraint</a>  <font color="#6f6f6f">Nature</font>

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Functionally constrained human proteins are less prone to mutational instability from single amino acid substitutions
Naturetech

Functionally constrained human proteins are less prone to mutational instability from single amino acid substitutions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPU0ljcjdiamxlY0lySVY3NVYwVTEyZ21GSVN1V01rdm55RnNZaW10cmV4dWkwVXNjdnBaMVFhTFBRYnVrQzlZLXVxcU45UUY1QWRJaXpGQVp4aHhOMlhr?oc=5" target="_blank">Functionally constrained human proteins are less prone to mutational instability from single amino acid substitutions</a>  <font color="#6f6f6f">Nature</font>

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Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin
Naturetech

Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9xQll3dmVsT2R6S1JlYWUxMENYbmJmN0NOVXJOOERyWjM4ZjdrMGx4RFJUWXVPRlg2VW5vekZsVDk3OVFhd1p5RzAzdjNyYVFua3Q5OUpOcjJrUXNGWXBz?oc=5" target="_blank">Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin</a>  <font color="#6f6f6f">Nature</font>

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Mutation bias reflects natural selection in Arabidopsis thaliana
Naturepolitics

Mutation bias reflects natural selection in Arabidopsis thaliana

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1DRVdYVG9fNFVyTGhsSkJCZXNZNmRHaXRIczF6aDBYeXFwVkpXVmItbnZsdEctb3EyQ1NScC1QZk5KMzN2TkNwWVQtMVVzV05xcTBrbVpoU05ZSHpOVHE0?oc=5" target="_blank">Mutation bias reflects natural selection in Arabidopsis thaliana</a>  <font color="#6f6f6f">Nature</font>

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Hotspots of human mutation point to clonal expansions in spermatogonia
Naturegeneral

Hotspots of human mutation point to clonal expansions in spermatogonia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBYOWZRS2RzX185ZHhLTlpNVHhFRkFFV1JyV2FUVkt2MVpMczZSSHhldUtObFFWSWNaeXFDWUFWR2hxMERBNmlrZ0FJYnhrVjFiLVlocXM1Nms4U3MteTNJ?oc=5" target="_blank">Hotspots of human mutation point to clonal expansions in spermatogonia</a>  <font color="#6f6f6f">Nature</font>

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The evolutionary impact of childhood cancer on the human gene pool
Naturegeneral

The evolutionary impact of childhood cancer on the human gene pool

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE52cC0yeTlfQzBiOVZtMTZJLTZRNVlRVjZDeERhdTVCT2I4MkRiMVF6OGNGdlZYU1pWeUtmYXhmVzNsZnQwbzJTcXAzREFnM2kzeFJ5X21hUjg4NzVCdXpz?oc=5" target="_blank">The evolutionary impact of childhood cancer on the human gene pool</a>  <font color="#6f6f6f">Nature</font>

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A method to build extended sequence context models of point mutations and indels
Naturegeneral

A method to build extended sequence context models of point mutations and indels

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBxWkxhTDBNQTVGMEdORG1SVk5aS3NRcU1xR0sySHI2RHRKVkx0ZDFWak55SGQtQWI5SWlrYU5PcUhPV3BEMGJIWmdvRWd4THRFV2R2Ulo5S0hYdjJmNzFR?oc=5" target="_blank">A method to build extended sequence context models of point mutations and indels</a>  <font color="#6f6f6f">Nature</font>

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Deep mutation, insertion and deletion scanning across the Enterovirus A proteome reveals constraints shaping viral evolution
Naturetech

Deep mutation, insertion and deletion scanning across the Enterovirus A proteome reveals constraints shaping viral evolution

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9hY2g0M2NKel95ZmZrLVlXRTJESmZzT2xoaUdlVlFyNHNNckZuS2l2NjJrMXgyNVBNU2czWE9aNjQ3Q1RCWXdObVlRQ2Z4OHFHSmFxOFFmTHdaYkt4Q25B?oc=5" target="_blank">Deep mutation, insertion and deletion scanning across the Enterovirus A proteome reveals constraints shaping viral evolution</a>  <font color="#6f6f6f">Nature</font>

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Evaluating drug targets through human loss-of-function genetic variation
Natureworld

Evaluating drug targets through human loss-of-function genetic variation

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE55ckFZdzZqekhyRUUxQXN3Tk5nX3ZXUGlTbHJJc09lQzNzcldESXZPRzZDZGRTbHBITXViZHZHamNxcXRscjlWTFRVRl9JOFRkRnlHSC1DdFpRN29YSlE?oc=5" target="_blank">Evaluating drug targets through human loss-of-function genetic variation</a>  <font color="#6f6f6f">Nature</font>

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A structural variation reference for medical and population genetics
Naturegeneral

A structural variation reference for medical and population genetics

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE9XRkJ5S1BrSjFFSWRFMnlVNjZHYTFxNURYNVBYcTVISGZWUW13RkVxdERmS3c3VGUyc1BtSWNmNzN5OG9nLUNFY1pfS2dRVlVNYXJmRkFYVnVIek5fX2c?oc=5" target="_blank">A structural variation reference for medical and population genetics</a>  <font color="#6f6f6f">Nature</font>

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A probabilistic graphical model for estimating selection coefficients of nonsynonymous variants from human population sequence data
Naturepolitics

A probabilistic graphical model for estimating selection coefficients of nonsynonymous variants from human population sequence data

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5LdVpWMFRJdVIxV1hyc2pFbGFvMGYySDZJNUsyQjVmT2psSkxBZXBnYTY2SFVLWUdwMHJESFFRSkFQUTFWV1U4Y0FiQnFMNGhZUVk0WVpFMElCV1ZRSXlr?oc=5" target="_blank">A probabilistic graphical model for estimating selection coefficients of nonsynonymous variants from human population sequence data</a>  <font color="#6f6f6f">Nature</font>

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A deep catalogue of protein-coding variation in 983,578 individuals
Naturegeneral

A deep catalogue of protein-coding variation in 983,578 individuals

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB4Vm4tSFkxVE02dXV2RXZkbVFMX2RackVkY0VBYy12SGZDNjJpX3JSdmxzUG9LZFF5V25RNnZFZDFNUzB1eWRBVnptSEtOMW5lbnZsdXlQTVhUbGM5ZkN3?oc=5" target="_blank">A deep catalogue of protein-coding variation in 983,578 individuals</a>  <font color="#6f6f6f">Nature</font>

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Identification of constrained sequence elements across 239 primate genomes
Naturetech

Identification of constrained sequence elements across 239 primate genomes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1vSkF3MFZoZUFMdWpfNldwcnIzY0ZKQTlSNXFJcTNpc3BvVzhHc3h3NWQwRzVWU2YwS2MyMVV5WjVJSUcyd09zVDVpbWhyLXotYUZVcllCS0lMN3cwOEZj?oc=5" target="_blank">Identification of constrained sequence elements across 239 primate genomes</a>  <font color="#6f6f6f">Nature</font>

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Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning
Science | AAAStech

Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE12aVNNaVFxNFNFcWN6M2t3R3JiR2Q2bGRoWkFqa1dGMHNFNFRGc1YzakhoQzBzRC0zbjc2YUZSWFY0M0RNMGxzWnlSRFFyVWhUUmFzU1BhWl9vUTVfNW1Z?oc=5" target="_blank">Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning</a>  <font color="#6f6f6f">Science | AAAS</font>

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Hypermutability bypasses genetic constraints in SCV phenotypic switching in Pseudomonas aeruginosa biofilms
Naturetech

Hypermutability bypasses genetic constraints in SCV phenotypic switching in Pseudomonas aeruginosa biofilms

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1YanAwQm1UN0paalhUbjF4QTNiOVktdnI4V0NjZS1qMmNYVEZQRHQ5anpFYXFmQXBkb09EcXE0ZVdfTHAwcnBfcHo4Tl8yc0dhNzFWd3lWUV9kNlhlNTkw?oc=5" target="_blank">Hypermutability bypasses genetic constraints in SCV phenotypic switching in Pseudomonas aeruginosa biofilms</a>  <font color="#6f6f6f">Nature</font>

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Scanning the horizon: deep mutational scanning approaches in virology
ASM Journalsgeneral

Scanning the horizon: deep mutational scanning approaches in virology

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTFByanFSaG9ET2YwUC1ZUVhLNzd6akhqY3FkcmxwS0wzdUUwb2pWUGhQTWtfQm56UnJNQ1JXVDJiX3FJRU9uMDF1YW5qOFFFUjRvWEtqWmNJcl9Ea0FBb3ZvSFR6bw?oc=5" target="_blank">Scanning the horizon: deep mutational scanning approaches in virology</a>  <font color="#6f6f6f">ASM Journals</font>

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Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes
Naturegeneral

Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5RR1llMUdmSWh6ZXJrd0VYeWY3QUJzZUl0RFJfSnI1UWN6QjdKQm1wblFQVktSTUFQdnNPajhqOW45UEFHWmUtbFNWd3BsTENTbmYtb21scmhiT2EtX0k0?oc=5" target="_blank">Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes</a>  <font color="#6f6f6f">Nature</font>

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Mutation protocols share with sexual reproduction the physiological role of producing genetic variation within ‘constraints that deconstrain’
Wiley & Sonstech

Mutation protocols share with sexual reproduction the physiological role of producing genetic variation within ‘constraints that deconstrain’

<a href="https://news.google.com/rss/articles/CBMickFVX3lxTFBTMkw0Vkpvay1pczJBSGQtbWt2ckR3TmpzYmNlM19yLV80ZDNLWlNHTFp0MjZDZzJ6Tl9faldCTzZlUlljN3REMWU1Z1REbGlIZHVtdzhOVGowUExSS05yOU1Qck85eTJ1NjNMamlfc09zQQ?oc=5" target="_blank">Mutation protocols share with sexual reproduction the physiological role of producing genetic variation within ‘constraints that deconstrain’</a>  <font color="#6f6f6f">Wiley & Sons</font>

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"The mutational constraint" — Live Google News Trends & Headlines