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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Targeting RNA structure i" (30 stories)

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Predicting small molecule–RNA interactions without RNA tertiary structures
Lead StoryNaturegeneral
Jan 2

Predicting small molecule–RNA interactions without RNA tertiary structures

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE92LXRRTWxuMjUwRFVPaW94Q3RYSmVyUGFnclVUSzAwUTJaV1JVRll5VFE4aldZLXJERzJkMU5tMmQ0LUJoNnpRYjloamNqQk92QTJJM0RhdmpaTEhWaFZ3?oc=5" target="_blank">Predicting small molecule–RNA interactions without RNA tertiary structures</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Targeting RNA structure i"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
RNA-targeting small molecules: a new frontier of drug discovery
Pharmaceutical Technologygeneral

RNA-targeting small molecules: a new frontier of drug discovery

<a href="https://news.google.com/rss/articles/CBMitAFBVV95cUxNOFAxaFc3OUk0RDBFQ1JGek5pdjVtS05nNXZ4M0NlZi14Y2xTa1VJTzNQODVPYy1lRmUzVlo1T3dkeGtQZGh5WHhUQUltR2xEM2gxUUNDbzAyZ1FtV2RmQVQ0dXVSN0VvOUIwT2lmcGVESnZua1o4VWRWV3VUREl5bzkyNlVvV1ZRX2xHSnY0RGZqR01QaEdwaHNYMFhqTTU1bnZQTXJCSEtuaFNmVElEeXFYYzU?oc=5" target="_blank">RNA-targeting small molecules: a new frontier of drug discovery</a>  <font color="#6f6f6f">Pharmaceutical Technology</font>

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Study shows how to identify drugs altering RNA structure and function
EurekAlert! Science News Releasesworld

Study shows how to identify drugs altering RNA structure and function

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE5XQVg1OXhydDNxV21ZeFhjZlY5enhBdEIxNjFqRkFuVHFXaHNNWnlPaU80M2dESzlPejFCTFBMVjV2UEhJNzgtM0lIdWtBY2pua3ZVd0hKMmItWXJW?oc=5" target="_blank">Study shows how to identify drugs altering RNA structure and function</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

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Accelerating small molecule discovery for RNA drug targets
News-Medicalgeneral

Accelerating small molecule discovery for RNA drug targets

<a href="https://news.google.com/rss/articles/CBMioAFBVV95cUxQWjdzbTVQSTd3eW5ORC1wU29YNVMyNG9tX0tXUVJscXNYQTNZUnpiQzNtVmoyeXRYWWpRYmpVZlh6d0JkWHFPM3hLRXlxRUhINTJHdWRkQjhITnNIOUlJa0xxS3M2NWx2YXV1YUJrUFRBaTFLd2JsOWQ2V3kwVjFUM256QVpfdTBUbENkc2ZEaGFGcE40dXIzaHJyV0gtZld1?oc=5" target="_blank">Accelerating small molecule discovery for RNA drug targets</a>  <font color="#6f6f6f">News-Medical</font>

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Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40
British Pharmacological Society | Journalsgeneral

Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40

<a href="https://news.google.com/rss/articles/CBMibkFVX3lxTE1RdXN5ZVhUOE5CR2cwN2l1N0RmY2wtbzlPTWJRa3Fpb0NVdWFheHhYekxNX3BRUTA4LVFITTFMOUVlRjQ3NWtYc1QyVlZ5dy1YczV0ckd3Umk4Y1ZxcTV2TTRSM1Q2NHZ1emYwVlR3?oc=5" target="_blank">Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40</a>  <font color="#6f6f6f">British Pharmacological Society | Journals</font>

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Systematic identification of variant-specific RNA structure-small molecule interactions exemplified by RNA G-quadruplexes
Naturegeneral

Systematic identification of variant-specific RNA structure-small molecule interactions exemplified by RNA G-quadruplexes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5KWlduZWtJN1dwaUZ1LVVrWE41SFk3TU9CZUdJVXJ0amxvcHJZNmtKQzdobzM0ckJDbE8tVXpGbjRmeWlwMzRQbml6dlo1X1FSMU1NbzF6TWNXTFdKd3Yw?oc=5" target="_blank">Systematic identification of variant-specific RNA structure-small molecule interactions exemplified by RNA G-quadruplexes</a>  <font color="#6f6f6f">Nature</font>

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RNA Targeted Therapies
Evotecgeneral

RNA Targeted Therapies

<a href="https://news.google.com/rss/articles/CBMiqAFBVV95cUxORlE1bnE3RndxUVgtRnRqY21hSWRtQTdyaWNJdGM5YzV4c1h2dGJGWEtpOVNwSHZxY015UzJuNl9MZThEc2g5Q2Qtd0pyWS1ZSEQyODN1bEt1Q2FsdGFKVmV6ckF2UEhFZWVST3ZUY1EwWkhEZ0tkZ2VGTzd1a0lVQW16LS1PNzgxVUlfTzl5Z2ptcHBmNVZuYVBHWEdDRkVaTWZOYmVrQ2o?oc=5" target="_blank">RNA Targeted Therapies</a>  <font color="#6f6f6f">Evotec</font>

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Targeting RNA-binding proteins with small molecules: perspectives and challenges
Frontiersgeneral

Targeting RNA-binding proteins with small molecules: perspectives and challenges

<a href="https://news.google.com/rss/articles/CBMikAFBVV95cUxNQ3VCa0QwMkc1V2JJc0tQWFhNTm5oSEQ5VmRQSzZTRHJLSmxhVWVFbkQ0VE5NMFQ2d25pZXFIQWRjZ29tbEJCVGdodnZnb25GVFZtcjQxR3V5LWg2T2ZJal9HRVFnUWZtT1J3NVdsdldFQ1R1ZXE2czZNOHJLVXdZdTJuc1ZIQlRwcEtBbFc1S1M?oc=5" target="_blank">Targeting RNA-binding proteins with small molecules: perspectives and challenges</a>  <font color="#6f6f6f">Frontiers</font>

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Generative Chemistry Platform for Small Molecules Targeting RNA: A Case Study for Chemical Optimization
Science Partner Journalsgeneral

Generative Chemistry Platform for Small Molecules Targeting RNA: A Case Study for Chemical Optimization

<a href="https://news.google.com/rss/articles/CBMiWkFVX3lxTE9Icm1RZF9mdTdyUENqMy1OUDcxdjNFZ01xa0NIUVd0eDBtWVhXZEpId0MtSW45b09HaDdEMjlKNG53VTFHR0Nwd29jZTBmM1QxMXF5Vkd1bDZ3UQ?oc=5" target="_blank">Generative Chemistry Platform for Small Molecules Targeting RNA: A Case Study for Chemical Optimization</a>  <font color="#6f6f6f">Science Partner Journals</font>

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RNA functional modulation by Mitoxantrone via RNA structural ensemble repartitioning
Natureworld

RNA functional modulation by Mitoxantrone via RNA structural ensemble repartitioning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE42QjFhN3dyQW1sUk5WeFJVbUhhR1c2N1lCb2Nxc3NNYTBiMGNSZ2pYMFJEeE04MXVSdktkRWJXQkN1RjQxMjFWVnJOYkVVenBENWlYOXp5Y3RxYm5SUXo0?oc=5" target="_blank">RNA functional modulation by Mitoxantrone via RNA structural ensemble repartitioning</a>  <font color="#6f6f6f">Nature</font>

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Using the structural diversity of RNA: protein interfaces to selectively target RNA with small molecules in cells: methods and perspectives
Frontiersgeneral

Using the structural diversity of RNA: protein interfaces to selectively target RNA with small molecules in cells: methods and perspectives

<a href="https://news.google.com/rss/articles/CBMioAFBVV95cUxPQkVweVdSaG5DMWNYRGpRRFA4OVhjR2ZRLUtUaU4tREJ4T29YTjA1Q0pCdUpyWkZtZ1JOR2QyMTRzSWZzSjJwdlZoTHA4eHRDaDZDc1puc0xlZkJwckRnTG41bVk3dTZKMXQ1Zzh5SzlpWVlPX2dpRUdqNnI2ZWx0UzZRWHJhbGNtMnJiSWl0d3Jnb2d6OHlSVkprb1MwMjZL?oc=5" target="_blank">Using the structural diversity of RNA: protein interfaces to selectively target RNA with small molecules in cells: methods and perspectives</a>  <font color="#6f6f6f">Frontiers</font>

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Targeting RNA structures with small molecules
Naturegeneral

Targeting RNA structures with small molecules

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5TY05SU2ZvRi1mdlpoZHU3S0Nabmc2NUtnRFlPUWtQLVVrcUwxLXVrNXNGSWdPcG1WR2ZSM2VleVdNdUl0S2t0NjA0Q0FYcXFGc3ZjcXh1SnpHQWh5emdJ?oc=5" target="_blank">Targeting RNA structures with small molecules</a>  <font color="#6f6f6f">Nature</font>

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Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors | Communications Biology
Natureworld

Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors | Communications Biology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAybnBobXlXd3lBU2JqTDBlQy0xdTFQbWdfb0ZHQzRCZ19Md2RDdjZ6Vi10aXBBZ3I4X1JKOFA1TThVbk9sbERhXzJpMDJqZHI1a25ST0xLY1FRblJaWk5V?oc=5" target="_blank">Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors | Communications Biology</a>  <font color="#6f6f6f">Nature</font>

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RNA structure modulates Cas13 activity and enables mismatch detection
Naturegeneral

RNA structure modulates Cas13 activity and enables mismatch detection

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1Xc0ZCWWh3UFVncTZqa3pOMWRPdHpobjE3eWlfMFpnNG05Sy11RlVKdGt6UmZpMVB2eGRMZVB3ZHJsRTRFeEtmYlJkZHNfa1dHRE1yRWlSdXViNFFiYVRj?oc=5" target="_blank">RNA structure modulates Cas13 activity and enables mismatch detection</a>  <font color="#6f6f6f">Nature</font>

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Large-scale analysis of small molecule-RNA interactions using multiplexed RNA structure libraries
Naturegeneral

Large-scale analysis of small molecule-RNA interactions using multiplexed RNA structure libraries

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1YaTEtODZTREFjT2RxNEFZS05PTWp0ekViUEtlSG5jZ28xX1pCY0huRElBM1NzakhUNVUwS1lLYVMzM2R1YUFhcmROWWxVMTFySGZFQVluOTRyY1N2eHZj?oc=5" target="_blank">Large-scale analysis of small molecule-RNA interactions using multiplexed RNA structure libraries</a>  <font color="#6f6f6f">Nature</font>

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Designing small molecules targeting a cryptic RNA binding site through base displacement
Naturegeneral

Designing small molecules targeting a cryptic RNA binding site through base displacement

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA5Um5FX2dNMHc3d0owcXM4a0xuSHpVdTZRSV9jbHFqNm9xOGtLWkRIelZPb3F6aER3YjhqM3NKNjNobkZhWmV2dUJxSEsxTVpWSVVrblJkY29pNXQzTUI4?oc=5" target="_blank">Designing small molecules targeting a cryptic RNA binding site through base displacement</a>  <font color="#6f6f6f">Nature</font>

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A strategy for small-molecule RNA degraders
Naturegeneral

A strategy for small-molecule RNA degraders

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE03VXhPWi0tcTcwV0NDRFJTai1xd0tJR2U3cVRScjVEWk9JUFZYLW44cHI4Y1FBS3dHSXU1VGthZEhsZWJVNnNkRE11ODdsSVBXWHZ0ZGdIbTNJVkE2WXA4?oc=5" target="_blank">A strategy for small-molecule RNA degraders</a>  <font color="#6f6f6f">Nature</font>

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Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes
Naturegeneral

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE92QUJGd0lRdU8xa29BZVpsQVozUjlqZnlMUjhidkpscmVCTHRLMkhMTGY4UnoxMmJzT0hFS3BEdkdSbXlVc0gtRVA2Q29LV2hzMEE3dzY0M0RNel9QM2ln?oc=5" target="_blank">Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes</a>  <font color="#6f6f6f">Nature</font>

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Targeting Xist with compounds that disrupt RNA structure and X inactivation
Natureworld

Targeting Xist with compounds that disrupt RNA structure and X inactivation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ad3hmb2I5RVcta0VpeHBJM1cyQTB3Wk9vRG5IT09wbTlBQXQ4Y1V4OFR3X0k3U3lwWmtrT2x5bnlNakNmUlBoWmNSV1VyaEI2RTJjTDI5WGNsaGlkbDRr?oc=5" target="_blank">Targeting Xist with compounds that disrupt RNA structure and X inactivation</a>  <font color="#6f6f6f">Nature</font>

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Structural basis of a small molecule targeting RNA for a specific splicing correction
Naturegeneral

Structural basis of a small molecule targeting RNA for a specific splicing correction

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTFBpLTE1S0JpRVpXUjEtTURwSE1RX3EtYXdvVnlMQllubHR3WTFjN2ZGNkxBNlZhY1I4aHE3bjUtcUxMTm9POUZuUDhPRmo1eEdiRHRtRm5pNlhjNHNYMlE?oc=5" target="_blank">Structural basis of a small molecule targeting RNA for a specific splicing correction</a>  <font color="#6f6f6f">Nature</font>

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Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures
Science | AAASgeneral

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9UcktEclQyZ3JvcU9ZTUpPLXh1aVFzRlk5alVFWXo5MHNqNlRjY2o5SEo5Slk0emRjSlRDSFRZUGJheFgwTVlTSUE4U0ktUG5ZVE9Hay1uejRPNHpDQWFr?oc=5" target="_blank">Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures</a>  <font color="#6f6f6f">Science | AAAS</font>

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Small Molecule Conjugates Unlock Targeted RNA Degradation
Genetic Engineering and Biotechnology Newsworld

Small Molecule Conjugates Unlock Targeted RNA Degradation

<a href="https://news.google.com/rss/articles/CBMirAFBVV95cUxNenZXZlM3empkMVVZc3Ytc053YnlnRUVZaWE3LWhDd0hSWFJpU0FCT2twbzRxSWs2aGEtYUhtUHUxQm91QW9jOEtackczMEFiN2xKVUVULXBsdnhOdjlHdm0tdmQ0OHlWbHMxRld1cW9MNERFbWdGWk9XNlozYlFYMHRxMkZELVZKemUzTnkyRHNMQ1hGaUtNdUctc0V6V0VxdndZaDBhTHZ4cDhR?oc=5" target="_blank">Small Molecule Conjugates Unlock Targeted RNA Degradation</a>  <font color="#6f6f6f">Genetic Engineering and Biotechnology News</font>

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Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN
Naturegeneral

Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9zUVhHR1NKRTZlaFdEelhGSE5Da3I1cmlDcEJCdHI2MXZsXzNUX05Hd3ZBT09vaDNfdU55clBFUUNIQmdFMVVNMlFSTGR3X01ka0hwZGlIcGVUZnN6MkFv?oc=5" target="_blank">Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN</a>  <font color="#6f6f6f">Nature</font>

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Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin
Naturetech

Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE04X0RJc3JndEJzbExqOTM5Z1ZmN3EzaFdQQzRmWlZNY3NBLVhNMWZlMXRNRV9pWE9fSWhoRERUcExTdWdUclB4TTdMZTVIdmppVXNiOS1XcFhfNzRHOWVn?oc=5" target="_blank">Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin</a>  <font color="#6f6f6f">Nature</font>

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RNP interfaces as regulatory “active sites”: a repurposing strategy for small molecules targeting viral 5′-untranslated regions
Frontiersworld

RNP interfaces as regulatory “active sites”: a repurposing strategy for small molecules targeting viral 5′-untranslated regions

<a href="https://news.google.com/rss/articles/CBMioAFBVV95cUxPU296dUFFeWl2UlJ2ZmwyTzBxbThBc1FhQ3ZBdDc3N2Z0ZzZwOVMyZWZ2U2k3NDVLYTVPcEhmekJXLWtoc0hvbFg3Y241WGRxLWNIci15eHFfaTRjMmtkUmRWQXlBel9DNnBtSkxQNEh1dWpKaHo0WEF0dGJseWJiMUZORWdfRllkMzRhT181ZUNmdVVKU1ZxWExqM0d2SGxO?oc=5" target="_blank">RNP interfaces as regulatory “active sites”: a repurposing strategy for small molecules targeting viral 5′-untranslated regions</a>  <font color="#6f6f6f">Frontiers</font>

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Programming inactive RNA-binding small molecules into bioactive degraders
Naturegeneral

Programming inactive RNA-binding small molecules into bioactive degraders

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9Ja19ENTlPcy1JQ25mVk9raUVrZU1wNVk2emM0WEZzRUF0Zkg5QkRVOGdmZnJEalNtdU50MWJlTVRWc0dVX3lrY0dLVHJEX2R4UTJFRWExcGNGOW1TM1lv?oc=5" target="_blank">Programming inactive RNA-binding small molecules into bioactive degraders</a>  <font color="#6f6f6f">Nature</font>

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A general fragment-based approach to identify and optimize bioactive ligands targeting RNA
PNASgeneral

A general fragment-based approach to identify and optimize bioactive ligands targeting RNA

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE80OTVFbTIxMFFlZlpOUzVsVG9ZdFQwTG9YN3hhN1lJdGQ0bnk0cFpmdkZQR0NZUkIyVmU0dTVJcDFuS0hFekpMclRpc1pQdkdJV0dCQWR6cWJFVjNa?oc=5" target="_blank">A general fragment-based approach to identify and optimize bioactive ligands targeting RNA</a>  <font color="#6f6f6f">PNAS</font>

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Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2
Naturegeneral

Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1nWk9GVGl2WFNRMmFUb3Jfc2hZU2NWNXlBM09qdzRpTEdiT05mSEllODFXVldNX2FIVktTTGo4b1pGQjhaWFdIM3Brb3BPVmdzb0Fnd1FlOFRpTDNzcXk0?oc=5" target="_blank">Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2</a>  <font color="#6f6f6f">Nature</font>

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RNAmigos2: accelerated structure-based RNA virtual screening with deep graph learning
Naturegeneral

RNAmigos2: accelerated structure-based RNA virtual screening with deep graph learning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBXc0NVakZYY1RtZFNsWXZtcVROeXVTalM0eWxCVlUwWVBnckkzZWpMNG1xT3k4V3lpaUNWeVZXb3ZIYllxNl9JOExkME1XX0R3X2JaZF9jdERtR3Foc2xV?oc=5" target="_blank">RNAmigos2: accelerated structure-based RNA virtual screening with deep graph learning</a>  <font color="#6f6f6f">Nature</font>

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Accurate RNA 3D structure prediction using a language model-based deep learning approach
Naturegeneral

Accurate RNA 3D structure prediction using a language model-based deep learning approach

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9NTDFEbzA5YVZVbnJabkhDWGp4LVJ3Z1Fob3ZJZzVJRVZxN0E2dUZGSTFkZ2RPU3VMLWtYNTZwOTlBUjZ0azgzVXBoSzZaQ0FyZG9mbzkwRVFlUUtzc2Nn?oc=5" target="_blank">Accurate RNA 3D structure prediction using a language model-based deep learning approach</a>  <font color="#6f6f6f">Nature</font>

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"Targeting RNA structure i" — Live Google News Trends & Headlines