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Category:All Headlines World & Geopolitics Markets & Economy Tech & AI PoliticsSearch results for: "Structure-guided discover" (30 stories)

Structure-guided discovery and engineering of miniature CRISPR–Cas12m for epigenome editing

Lead StoryNaturegeneral

Sep 16

Structure-guided discovery and engineering of miniature CRISPR–Cas12m for epigenome editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9hTWVkVDRUbnk5cUMtbldhejJYZjlWRlphTU9wRzdFcENGcmU0NzJaeW9sckJWd3JsZXJSUFVfRWV2RHVkV0FWZTJ3V2cyNzdqNGJxTG9ReGI1TTBwQ2Rz?oc=5" target="_blank">Structure-guided discovery and engineering of miniature CRISPR–Cas12m for epigenome editing</a>&nbsp;&nbsp;Nature

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Search Results for "Structure-guided discover"

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Thermo Fisher's South San Francisco cryo-EM center offers drug developers a proving ground for structure-guided discovery

R&D Worldworld

May 20

Thermo Fisher's South San Francisco cryo-EM center offers drug developers a proving ground for structure-guided discovery

<a href="https://news.google.com/rss/articles/CBMi5gFBVV95cUxPdWtpTFJ2M3o2T2xqVktTMVhuNHpsQUtOdFRHYmxQVWN3b3ZnNnp1dGZORHBkR3FrR2lQeThsdWtaMHR4eUh6SHhkMkR4REJPMkxLMlU4V0tYb3dqcjdocTNjMzBtMFRwcmxrUll2NGxwQ20yRTNxQWlUOGlLbXN6S0RyY3FGX3JOVUxEdGIya05XUF9lQ2tDYVdURFJ5cGRINWYwc0JoUGhFZlB3ajdtV193bGxJSEdkOHhGMHo1MXRfZEVCbnlBT0p0cW1USF94dVE4S2NkUHIwbXU0OE14T0JjX0tiUQ?oc=5" target="_blank">Thermo Fisher's South San Francisco cryo-EM center offers drug developers a proving ground for structure-guided discovery</a>&nbsp;&nbsp;R&D World

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Structure-guided discovery and engineering of miniature CRISPR–Cas12m for epigenome editing

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Search Results for "Structure-guided discover"

Thermo Fisher's South San Francisco cryo-EM center offers drug developers a proving ground for structure-guided discovery

Beyond one drug–one target: AI-guided discovery of multi-target antiviral therapeutics

Breaking the Myb–KIX Alliance: Structure-Guided Discovery of Biaryl Hydroxy-Naphthamides as Disruptors of the c-Myb–CBP/p300 KIX Protein–Protein Interaction

Prioritizing neuroactive ligands using motif-guided virtual discovery and zebrafish profiling

Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases

Structure-guided discovery reveals ancient clade of Cas13 ribonucleases

Cross-protective human antibodies against the Mpox virus discovered through structure-guided screening

Structure-guided discovery of a single-domain antibody agonist against human apelin receptor

Structure-guided identification and biological evaluation of reversible EGFR C797S inhibitors

Structure‐Guided Discovery of a Potent Inhibitor of the Ferric Citrate Binding Protein FecB in Vibrio Bacteria

Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface

Language model-guided anticipation and discovery of mammalian metabolites

Navigating structure-based drug discovery with emerging innovations in physics- and knowledge-based approaches

Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence

Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin

Structure-guided discovery of anti-CRISPR and anti-phage defense proteins

Structure-guided phage display discovery of antibodies for (S)Tn-glycans in protein context

Structure-guided Discovery of Dual-recognition Chemibodies

Developments and challenges in hit progression within fragment-based drug discovery

Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism

Scientists Design Molecules “Backward” to Speed up Discovery

Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin–neuraminidase inhibitors

Structure-guided design of partial agonists at an opioid receptor

Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity

CryoSeek: A strategy for bioentity discovery using cryoelectron microscopy

Protein-structure-guided discovery of functional mutations across 19 cancer types

Structure-guided drug repurposing identifies aristospan as a potential inhibitor of β-lactamase: insights from virtual screening and molecular dynamics simulations

WRN structural flexibility showcased through fragment-based lead discovery of inhibitors

Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells