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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Spatially clustered loci" (30 stories)

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Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration
Lead StoryNaturegeneral
Sep 6, 2019

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1HVUlFSTRvWDVraVNtdHVTN1NSekppdFFYVk9ETkhPYmZfRHVhZ3NIN1FKdGhsUHAzQnh5eEtPUS0ycExwcmpjVkR0VkU0ZUlpMkZwNnppY0taTDR3XzZR?oc=5" target="_blank">Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Spatially clustered loci"

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29 stories displayed
Spatially decoding genotype-associated epigenetic landscapes in human lymphoma FFPE tissues via epi-Patho-DBiT
Naturegeneral

Spatially decoding genotype-associated epigenetic landscapes in human lymphoma FFPE tissues via epi-Patho-DBiT

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE40eWw1aGtMWVI5RzNJcGtSd2RWdGRpMklTU1lTWXo0dktWRGlHTFROWlo5UHU3dVBNSXBMc1I2YXpITjgzMUhVZ1BPbExzX1piTVhpUkVYU2lIYXpMWDZr?oc=5" target="_blank">Spatially decoding genotype-associated epigenetic landscapes in human lymphoma FFPE tissues via epi-Patho-DBiT</a>  <font color="#6f6f6f">Nature</font>

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An experimentally-informed polymer model reveals high resolution organization of genomic loci
Naturegeneral

An experimentally-informed polymer model reveals high resolution organization of genomic loci

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4taTc4MElmMnVoYkFlSVdFNEFsaTJ3SFVoeXJFMkVVSk1iQXY4ODBCa0NHRjlYa3I3VzQyZllzVGhZZktjcXVEWHVTWk9QQnEtV2JsTEZ4NWt2a0ZiR0VV?oc=5" target="_blank">An experimentally-informed polymer model reveals high resolution organization of genomic loci</a>  <font color="#6f6f6f">Nature</font>

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Roles for Non-coding RNAs in Spatial Genome Organization
Frontiersgeneral

Roles for Non-coding RNAs in Spatial Genome Organization

<a href="https://news.google.com/rss/articles/CBMiqgFBVV95cUxObGFZdlZ4cXg2dE9UdDJ1V29EVXF2UnhmQTcwcHZIR08tTlJSWWVGMFAzMXRuNFRsTF9ZNEgzNkN4cGZ2bG8zMk1DQW1xaG9IWThPNjNPLTJybmZsWWtodHp3ZGFFbndGaVlic0FhU2k5dmtrVmd2al8zOUVWT0ZqVk5rWDNsa2V1YzVwbGRkcWFMN3N3TFdCM01FS29hMjFzcEdoSUx2Ym4xQQ?oc=5" target="_blank">Roles for Non-coding RNAs in Spatial Genome Organization</a>  <font color="#6f6f6f">Frontiers</font>

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Spatial-temporal genome analysis and its application for the prediction of functional systems in bacteria and archaea
ASM Journalsworld

Spatial-temporal genome analysis and its application for the prediction of functional systems in bacteria and archaea

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1mRkFzZDkxMm5zakxHeFNVOU9ydnhNeDAxZFBLcmdwcFVPa2xUbWNpbG9ZSjV0SHpSS1BNeVI3YlQxdjJ3YzV2Ml9WeUt3ekhmQW4wX1VhT0I2OFFWVHFn?oc=5" target="_blank">Spatial-temporal genome analysis and its application for the prediction of functional systems in bacteria and archaea</a>  <font color="#6f6f6f">ASM Journals</font>

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Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states
PNASgeneral

Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE4wQmozVFdpQVQ0MFU3aElsSUZqYkJTRXg3TFJmSXVBSi1fZXpBZVVvbFZTLURQMzU3WjlTYmwzRVRQRHo0MmhvM25JS3JORWlRclVnWGNPMTVBYXFq?oc=5" target="_blank">Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states</a>  <font color="#6f6f6f">PNAS</font>

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Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs
Natureworld

Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBhRUpWbldfSkVaWVZvWDhyQnowLURKZTFRVXNMT0JlNE5iQVhyWDhWSlJUdlFnZmlfOU1zOXlHYlo1MDcxZ0s5OHJIZEFzWndYemVieFpqd3A4NDl0cGRJ?oc=5" target="_blank">Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs</a>  <font color="#6f6f6f">Nature</font>

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Spatially clustered type I interferon responses at injury borderzones
Naturegeneral

Spatially clustered type I interferon responses at injury borderzones

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBxc0plRmo1WFdvbVliZ0ZzTjI5ZTRJQ053SGc2T1Y3SERjSFB3TjBLWE5RS1Z1ZGM2Q2ViT05sWktxcml4Zmw5OFZ6eVN6THBLdmZVM0plZDdodnNRUElr?oc=5" target="_blank">Spatially clustered type I interferon responses at injury borderzones</a>  <font color="#6f6f6f">Nature</font>

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Spatial joint profiling of DNA methylome and transcriptome in tissues
Naturegeneral

Spatial joint profiling of DNA methylome and transcriptome in tissues

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1COVJ2dktQQUV3YUt3VUE0UFpMTl9pYWxYTmhEeFZ5ZnNPMGtJbkNOYTQyUzc3YmZWbmc5S21VMTdGcHB6YlhvOFJYaE5CaDh1MjVlRnl1YWF5VGFObFNZ?oc=5" target="_blank">Spatial joint profiling of DNA methylome and transcriptome in tissues</a>  <font color="#6f6f6f">Nature</font>

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Spatially resolved mapping of cells associated with human complex traits
Naturetech

Spatially resolved mapping of cells associated with human complex traits

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE41U05Fc0tzWkJvZ0xYODZnanludlAxS0Z1X0NsYnZGbUE1UmJNVWRROU56VzRrZFdhTy1tVXFBZm5nclhNQXphLVhJdG9fUkhiWE9BcFNfTldlaVlpUTdF?oc=5" target="_blank">Spatially resolved mapping of cells associated with human complex traits</a>  <font color="#6f6f6f">Nature</font>

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Solid-phase capture and profiling of open chromatin by spatial ATAC
Naturegeneral

Solid-phase capture and profiling of open chromatin by spatial ATAC

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE10eDN0YWliak1VZno1RkFCTkRpblNxb09jRHRxU3Z3Rjh4dU9DME5pZGVjVzRrTXZySUZFUHg0MGxoZlU0UF9uMDg4T1JNVm1NZmxySVRIckNqRGdWS0xV?oc=5" target="_blank">Solid-phase capture and profiling of open chromatin by spatial ATAC</a>  <font color="#6f6f6f">Nature</font>

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A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH
Naturegeneral

A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1nVTQ2VFRwYklfdGwtTGpOQ2ttWl9oeGktajhyb05yTVFUZmVsOGdweFM1VEwtOU0zaFRLZDZRU1NULVhKS1RuRmFYYnRxeWpKLVY5MWlIR1Z1dXJseXI0?oc=5" target="_blank">A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH</a>  <font color="#6f6f6f">Nature</font>

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Spatial profiling of chromatin accessibility in mouse and human tissues
Naturegeneral

Spatial profiling of chromatin accessibility in mouse and human tissues

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1QakRoMkFDUjRBY1JnWDkxN05Zb1UzSHNRQmlwNzA4SU5ZX2RvMURHd29nZmh4b3JkYmk2V29tMjhtamZEZk5CdXZQbFVpVTlIcDdESlZBRlF1NHdUc0kw?oc=5" target="_blank">Spatial profiling of chromatin accessibility in mouse and human tissues</a>  <font color="#6f6f6f">Nature</font>

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Inter- chromosomal contacts demarcate genome topology along a spatial gradient
Naturegeneral

Inter- chromosomal contacts demarcate genome topology along a spatial gradient

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1pUmE4OVlVRS1oSmFzYUtMQ1B1cEQ3TTFhNXpVVGNmai1LdnplY3JFcXE0UWJndmkwQXVUU0MwSmJmOGZOLUlCMTFJaUN2RU9wMW9FTk03U3JkbnFaQWpn?oc=5" target="_blank">Inter- chromosomal contacts demarcate genome topology along a spatial gradient</a>  <font color="#6f6f6f">Nature</font>

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Divergent combinations of enhancers encode spatial gene expression
Naturegeneral

Divergent combinations of enhancers encode spatial gene expression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0yRVZTZE41MXdZQ3I0TF9fZWJ1MUEyWW8yZDdGNFIxTUZISU00ZHBFUXoxR2VybFJTU1dNUnNhZnBVSm9ZOUJZMl9ZeTN0WmN3M2x2UktVajRFM3FPTkNV?oc=5" target="_blank">Divergent combinations of enhancers encode spatial gene expression</a>  <font color="#6f6f6f">Nature</font>

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Multi-omic spatial effects on high-resolution AI-derived retinal thickness
Naturetech

Multi-omic spatial effects on high-resolution AI-derived retinal thickness

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBLWS1Yb3BzeWdHZ1RRR2RHek5VQk1vdy1wbVZXVTlGUExJZnlDYVFVX0dHQm54MWRHV0s3TW1xNEZ2aTV3WEJTblYwcklNbEtJYkVvWDRhbWNqMXNIb1RZ?oc=5" target="_blank">Multi-omic spatial effects on high-resolution AI-derived retinal thickness</a>  <font color="#6f6f6f">Nature</font>

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Spatial profiling of chromatin accessibility in formalin-fixed paraffin-embedded tissues
Naturegeneral

Spatial profiling of chromatin accessibility in formalin-fixed paraffin-embedded tissues

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5IOEtZYTFHa2drZ2hzZ01NNng1WVZ1ZlAxcmpMR0FOU0pqVVhuODMxd3NhUUs2SUpfb2hCX2ZMTlcwQkJNYlJHWmpjVHRVbGFld3duRnowQjZuMGVhSjI4?oc=5" target="_blank">Spatial profiling of chromatin accessibility in formalin-fixed paraffin-embedded tissues</a>  <font color="#6f6f6f">Nature</font>

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Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities
Naturetech

Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5YcHBHNXdJTW9LaWhRTjkybjY3S3Q1MDI4cjJReVM0WEN5Y0piR1NnTTU3TXp0TmdtMlpXY1h0UlIyVWRoXzU5WjFpTGRwQVk0TG96U2tseGVfT0dZaTVJ?oc=5" target="_blank">Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities</a>  <font color="#6f6f6f">Nature</font>

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An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus
Naturegeneral

An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE05dzVyQXdYS3VZWkFvb3NSYkRWaFI4RC1kNWp6cElYek1UVUtkZjQ1RjFaZ01yODAyVjVGaUVTT1Q0b3VUWVBMdDU2eEg3bFN5Ti10cWFIa0tnbFN1cGg4?oc=5" target="_blank">An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus</a>  <font color="#6f6f6f">Nature</font>

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Modulating gene regulation function by chemically controlled transcription factor clustering
Natureworld

Modulating gene regulation function by chemically controlled transcription factor clustering

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBERVBqdWFyVW9sRG1yeG5jdXRPRWZXdE52YUxMdmhRSGs2Q1RlLV95dllKRWZwZGxHYUFQSGJFRVVZaVp5QjlCVFNVNHJkTVVITDhSTVRwaENTYkFKYWMw?oc=5" target="_blank">Modulating gene regulation function by chemically controlled transcription factor clustering</a>  <font color="#6f6f6f">Nature</font>

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Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology
Naturegeneral

Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1jcTJVY0twUHF6eGVDczhXX09rVHBUd21PMzdKdHdGZEVWdUp0MTRJbVZvUDdGY3k2U2k5VFZxVUZuNWFnZ1Boel9qRU5MVkVfR0thd1BwczFpdF93R0E4?oc=5" target="_blank">Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology</a>  <font color="#6f6f6f">Nature</font>

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Genomic rearrangements and the evolution of clusters of locally adaptive loci
PNASgeneral

Genomic rearrangements and the evolution of clusters of locally adaptive loci

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1TVEtJNTZTaWRLZDI5dzU3emFtVldvdjVlRFhEUDFLeW9uYUZRU25QNThtUnpTVXJpd1ZMME1SaVdBd2ZXSmRvbkkxXzFQNUJ2UU8wT0pGS1QtSU9F?oc=5" target="_blank">Genomic rearrangements and the evolution of clusters of locally adaptive loci</a>  <font color="#6f6f6f">PNAS</font>

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Chromatin alternates between A and B compartments at kilobase scale for subgenic organization
Naturegeneral

Chromatin alternates between A and B compartments at kilobase scale for subgenic organization

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5abEphVlhlbHJ6YklUUTloRkRULVdkRGlIR3hXQk82WW9mRjJMbG9sVmFXQVhGQWFtNnIzWkdJZWFOdnJUQ1VZRWtBSUNVblFLUkxpM2FzMXR4VFU3c0NF?oc=5" target="_blank">Chromatin alternates between A and B compartments at kilobase scale for subgenic organization</a>  <font color="#6f6f6f">Nature</font>

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A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci
Naturetech

A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5FXzg3ZV9VeVkxVDB1cWJmMXdRcmpwZy1rZmY5ZVB6TlNRQ1BFRUdEY3FHZ09EemdNd3ZPdDRqOWVoUHpiMDUwc1hYcWhmVW9ZZ0h6Z2lySDZBRXZzU0pV?oc=5" target="_blank">A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci</a>  <font color="#6f6f6f">Nature</font>

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Super-enhancers in immune system regulation: mechanisms, pathological reprogramming, and therapeutic opportunities
Frontiersworld

Super-enhancers in immune system regulation: mechanisms, pathological reprogramming, and therapeutic opportunities

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPdW9fSHVBRUJQUmt4ZGEyVXFTLWNaN0x6ZUJtNnc0RVhYS1U1VVJRZmhoa3FmeWtoYTUycC15a3hZdkFMdGMyMmJKVC1JWWRwLW1Ec2VaOUprVDFsT0JGT3pIU0FyODRoajJOOWZBd21MQ25JZU5MMmk4ZUhYdG9kSnVTbm13eGYtd0NFRlRTX2ZCZw?oc=5" target="_blank">Super-enhancers in immune system regulation: mechanisms, pathological reprogramming, and therapeutic opportunities</a>  <font color="#6f6f6f">Frontiers</font>

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Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers
Naturegeneral

Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA3NHMwX0YtZXJLV3ZyWnBKRUhMVS0tczVmVkRqcjg3UGptWEl4aC03UllFR1lfOTloT01oTklmaWJBRXdZVXFzWmF4M2dZeHlsdkZzWDNlRXMtSUZSLUxV?oc=5" target="_blank">Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers</a>  <font color="#6f6f6f">Nature</font>

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3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes
Naturegeneral

3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE8xRmo5THd3OHJ2dWpqYzJ1Wk80Uk5MYW1GcU9wazQzdHZfamJpZjMyYWtMYzlxSWp4ZjBDbDlNMElMQ2JWVmdOaVN0WlZPeW9uQW9vVg?oc=5" target="_blank">3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes</a>  <font color="#6f6f6f">Nature</font>

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MATES: a deep learning-based model for locus-specific quantification of transposable elements in single cell
Naturegeneral

MATES: a deep learning-based model for locus-specific quantification of transposable elements in single cell

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5LdUI2ZkJZdUZhUEd3V0MxQV94WGV0WW9CeUlWUy1tOHNSTEtIcjBGWTlKRW5JWWU3V0JFNTlHbm55dk1wMlFQQ3d6QkVQTE5zaXdiMHY1eW9SSy1YN1Vr?oc=5" target="_blank">MATES: a deep learning-based model for locus-specific quantification of transposable elements in single cell</a>  <font color="#6f6f6f">Nature</font>

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Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer’s risk gene mutation | Molecular Psychiatry
Naturegeneral

Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer’s risk gene mutation | Molecular Psychiatry

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE83V3AxMy04LThZclNuYlc3ZFhfaDRUTVRGMUpBdDZHQldoX3JxVzMxTDVnYlkxaGxHVGk3UVlta3BFcFZLckMwNUx4eWhFZEVBdWlESXgtSWNEdDZqdHhZ?oc=5" target="_blank">Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer’s risk gene mutation | Molecular Psychiatry</a>  <font color="#6f6f6f">Nature</font>

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Cajal bodies are linked to genome conformation
Naturegeneral

Cajal bodies are linked to genome conformation

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE1IRTdYbHY3YXJUM0dWeUVIU3haYnZEUlBoYnR3RFRLZ0lCUUhBemRoUEFSSS1UTHpDWHNsWlp4SnRPX216RnhfbzZmZ2hYTmZxZUJqMjln?oc=5" target="_blank">Cajal bodies are linked to genome conformation</a>  <font color="#6f6f6f">Nature</font>

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"Spatially clustered loci" — Live Google News Trends & Headlines