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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Somatic mutations disting" (30 stories)

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Somatic mutations distinguish melanocyte subpopulations in human skin
Lead StoryNaturegeneral
Apr 27

Somatic mutations distinguish melanocyte subpopulations in human skin

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE93ck8tVjA2WjZqSmVVdXhPS0NMdGl2MUxoUWxPMldaT0huUHRxczN5RmhaSW1EMmhxWkRLSjNnYVF4d040LTZUODAyTndhQWJCM282R2ctLTdSNnA3SVhF?oc=5" target="_blank">Somatic mutations distinguish melanocyte subpopulations in human skin</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Somatic mutations disting"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
A New Way To Think About Age and Cancer Genetics
Harvard Medical Schoolgeneral

A New Way To Think About Age and Cancer Genetics

<a href="https://news.google.com/rss/articles/CBMid0FVX3lxTE80d25lNzJIYTBiQ1g2WlhtOUR0ZUFiQWVJT3BUa2NXWUJLZVlYNGxkby1iWHNXRHZIb0J3RHJCNXdnMlgwTGZKSThtQWw3TlRMWkZ6TUExbVctc193eDBvU093VmZGQlNuQTU4QXJJYy1LTnRLSXNJ?oc=5" target="_blank">A New Way To Think About Age and Cancer Genetics</a>  <font color="#6f6f6f">Harvard Medical School</font>

Age distinguishes selection from causation in cancer genomes
Naturepolitics

Age distinguishes selection from causation in cancer genomes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4tWGdmRGFyQUplY041R2ZqWi1VWEpVbUFEdWFzU2dQZVVhMDd0U0JGcE1zc2FseG41UmV6RVZtak41bnBWSmVJTGw3d2tQV1dpNGw3OW9wYTFNZVFXUkFV?oc=5" target="_blank">Age distinguishes selection from causation in cancer genomes</a>  <font color="#6f6f6f">Nature</font>

Germline vs. Somatic RNF43 Loss-of-Function Mutations: Distinct Colorectal Cancer Risks and Phenotypes in Population-Based Cohorts
Vera Healthworld

Germline vs. Somatic RNF43 Loss-of-Function Mutations: Distinct Colorectal Cancer Risks and Phenotypes in Population-Based Cohorts

<a href="https://news.google.com/rss/articles/CBMiekFVX3lxTE1HaDFJMDRTelRGSzkyaThJUC01anJNSktXdTdLOUczZlhIaUxLN2ZKT2thejNRZXBsOVktNkdkemJXbjNCSU9WblU5R0s3cGtzYVhQU0VSbHZ3TmtJcGFuMmViaEh2SlpzQ18zU3FJbm1VWW14RjRzSkJn?oc=5" target="_blank">Germline vs. Somatic RNF43 Loss-of-Function Mutations: Distinct Colorectal Cancer Risks and Phenotypes in Population-Based Cohorts</a>  <font color="#6f6f6f">Vera Health</font>

Shared inheritance reveals landscape of somatic and germline cancer risk in TP53
medRxivgeneral

Shared inheritance reveals landscape of somatic and germline cancer risk in TP53

<a href="https://news.google.com/rss/articles/CBMifEFVX3lxTE51NDdaYkhFSnBVZVJfeW9USkNOcEFsLVJhdXVKWHNBUUVGcWlFR1ZLYjBnV1V5ZlJEdFFMVEZ4ZmhldTJkZVZFWXRmbHVOLWo0M25iVkk3cTBSS1l3WFRxVkZGRS1QNllyMmJyNnR6SkJBYS05UlJoaE1BOXI?oc=5" target="_blank">Shared inheritance reveals landscape of somatic and germline cancer risk in TP53</a>  <font color="#6f6f6f">medRxiv</font>

Cancer-driving mutations are enriched in genic regions intolerant to germline variation
Science | AAASgeneral

Cancer-driving mutations are enriched in genic regions intolerant to germline variation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE80aDFfaFJweXcxRnRHQVoxXzhPeUVtMWRZNlRqNXd0QWkza2lvb2l5aXJ0SDRhQ0liOV9WUlJCaGpNVV9ibVJ5LUxzbFN0ZzBUX0pDSDlTdVVyanRLMzN3?oc=5" target="_blank">Cancer-driving mutations are enriched in genic regions intolerant to germline variation</a>  <font color="#6f6f6f">Science | AAAS</font>

Blurring the Lines Between Germline and Somatic Mutations in Cancer
OncLivegeneral

Blurring the Lines Between Germline and Somatic Mutations in Cancer

<a href="https://news.google.com/rss/articles/CBMinAFBVV95cUxNX3pzLWpkMkpVQUFQZjVuVk1ZamVvQ3ZESVUxdUFDaUdqNHdRSXFRZnk4enkyRkpOdG1oYlctOVlCV3ZRbGltSjhsV1BtSFpsT0lzLUlyd2RUMUxuNVNGUmRSVnB5dUwzZDFBdThJd3JDcC1LdFk0aWxVN3lKS1VxV1ZIcnE1R3NyYnZDaWtTQnBnX01tWXNXWEJhREM?oc=5" target="_blank">Blurring the Lines Between Germline and Somatic Mutations in Cancer</a>  <font color="#6f6f6f">OncLive</font>

Distinct gene mutation profiles among multiple and single primary lung adenocarcinoma
Frontiersworld

Distinct gene mutation profiles among multiple and single primary lung adenocarcinoma

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxORG5EMl9YT3U3dHVjcUVLczQtVHJBTW5VT0dROHFSQXBWNTY0SWk5R0hkVXRzbExYaXpEZFlaQVBmYmt6VUEwd3ZKdUh1azRyZzY1SjdBRzZmTWxJenBZb1JORVJMOEdkSVZKX0R1VHNhNV9pang2VS1OZ05nblNMRGJ2TmFsbWliY1NwVWJB?oc=5" target="_blank">Distinct gene mutation profiles among multiple and single primary lung adenocarcinoma</a>  <font color="#6f6f6f">Frontiers</font>

Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity
Naturegeneral

Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5LVUVhTmJwQURDRkdkM3N2R2V1a3dOdzZKdmx3LWV5RzNNcjc3Vm9VOGcxMVNtVWh5SUtoN0RuTmZiSnFyeU1OWXJoOFRsX3hKWktlS0pZSy1iTkRCWnpr?oc=5" target="_blank">Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity</a>  <font color="#6f6f6f">Nature</font>

Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis
Naturepolitics

Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5QVkdtcVlLX0FfSFRmQUp3R0lrYTR4eXUyb2E0dDNNVFZvbjJUMlRWQU9qemVMUG1jenVRd3ZwV3g5blJZNms2QzJxMk4yRi1ua1RhajZoWEg5N1dqWGdJ?oc=5" target="_blank">Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis</a>  <font color="#6f6f6f">Nature</font>

Prolonged persistence of mutagenic DNA lesions in somatic cells
Naturegeneral

Prolonged persistence of mutagenic DNA lesions in somatic cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1LS3hmYUxsWTFPN0c2X3lBUjg4V3RoQ2xveTZYR1FrVC1FRE9sb19jQmplS1gyVVdiNTIzR2k4bFdyZEU4aUhZOHltNGp4Z0pvM29kV0JtUFhrV3VEamZJ?oc=5" target="_blank">Prolonged persistence of mutagenic DNA lesions in somatic cells</a>  <font color="#6f6f6f">Nature</font>

Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
Naturegeneral

Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE42YmZMYmFpUXVwb0JGaUFLUzBxY0dyOGJWenZoRzV3UFNscnV0WWFPTFdfdWpJUEZlMGs1ME1Ob2E3S3RMWEdIbGRwejBMcC1DcDh3UTlnTWFueDdkWklj?oc=5" target="_blank">Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome</a>  <font color="#6f6f6f">Nature</font>

Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance
Naturegeneral

Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBwTnFGblZ4bHBZbW1Pa2dPUkNsOU5ERjBVRlZmaGJSWWhZOTg0ZFhDY0dULXJobElvM090X1hrWEZERTVxT0JyWkdjTnR6YnZfdUZLNDgxRnpvSDdCLW9z?oc=5" target="_blank">Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance</a>  <font color="#6f6f6f">Nature</font>

Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma
Naturegeneral

Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB2Vl8zN2hOZEFKVUZpdWVnaDBQbnVZNHo0ZWZyZ2JhSFhBNVBubDltWHgyR2FkZ1Q3bzByWm1pTEdYX3YxMVRmdm5kckcxVHBELXBPcjhXNm1WejZpVUVv?oc=5" target="_blank">Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma</a>  <font color="#6f6f6f">Nature</font>

Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer
Naturegeneral

Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1JSTNUM3VDYm8xX2xEazk0b3lVa0lBRlFYMmduTUU3VWgyQ3lDQVdmREtRSjVXZEVCeEhsRVlWUi14alE5emlqRVFUeU5JLWV6Z3RzcElkckNwd3hEQ21r?oc=5" target="_blank">Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer</a>  <font color="#6f6f6f">Nature</font>

Inflammatory leiomyosarcoma is a distinct tumor characterized by near-haploidization, few somatic mutations, and a primitive myogenic gene expression signature
Naturegeneral

Inflammatory leiomyosarcoma is a distinct tumor characterized by near-haploidization, few somatic mutations, and a primitive myogenic gene expression signature

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFBFWXhTanFGcGFqTTZKSHBDcVNyUy1lNkJ3ZmlEdS1TZmJZUlN1QUVTZGoweU14Y3E0NWhJd0l4MXk0ZkR6VTZYMGRfSUVodzVtUi0ta1JZZVdzc3FB?oc=5" target="_blank">Inflammatory leiomyosarcoma is a distinct tumor characterized by near-haploidization, few somatic mutations, and a primitive myogenic gene expression signature</a>  <font color="#6f6f6f">Nature</font>

Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs
Naturegeneral

Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE1rLVFzR0tKWUdmOUtDa0h2Y0VmTjFwNVNhaU95dEhqMDlfWGNpNDhfSC1iTGl2NkQySGtKbFdSUk9vUmtyQ0R2aVNYTmFnSlQ0ajBod1Rn?oc=5" target="_blank">Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs</a>  <font color="#6f6f6f">Nature</font>

Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer | npj Precision Oncology
Naturegeneral

Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer | npj Precision Oncology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE50dWJnekxDcTctbTdWOFpKZ2hwWlFiYVJfdDR6WHRvNktZRmhRd2g0elZQZmxmMHM3TzNKQ0lRb0VYUHpjcW9TZ2NqRkJHOEphaHI0MnpFWE9wcDk4SGln?oc=5" target="_blank">Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer | npj Precision Oncology</a>  <font color="#6f6f6f">Nature</font>

A genotype-first approach identifies high incidence of NF1 pathogenic variants with distinct disease associations
Naturegeneral

A genotype-first approach identifies high incidence of NF1 pathogenic variants with distinct disease associations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5rWHRrV1pSUVpQRFBSam1teTItTVo5VFpZb0xTTlp4emhycEJjOWgyMkg5ZzY3RFgzMkJjaG5LOUNpc0FJZXIycm5SbXJEMF93ZFE2YXFFdHN4LTFaTEM0?oc=5" target="_blank">A genotype-first approach identifies high incidence of NF1 pathogenic variants with distinct disease associations</a>  <font color="#6f6f6f">Nature</font>

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups
Naturegeneral

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE83YVdrZ2pCRmFYWkZ1N1ZWUTc2WExoT2Jjd3dVRjJNSDJ3Z0lOX0FzRkJ0Tl9hMUZoRnNNWjVwN04xd2NFa2hRa1Z3NkFwal9vemdSXzJyUFRSaHhmNlE?oc=5" target="_blank">TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups</a>  <font color="#6f6f6f">Nature</font>

Predicting high confidence ctDNA somatic variants with ensemble machine learning models
Naturegeneral

Predicting high confidence ctDNA somatic variants with ensemble machine learning models

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE02aDlLbzRtNWdseWVuVmRnYzVNTDZkTlFDbkJSWkU4LVV4OUlFWDJxOWw4NGJKaVVvZWxnSzdKZTlURXFQSWllUEEzWXNGM0tLZkZfWWhCSGR3LTZOQ1kw?oc=5" target="_blank">Predicting high confidence ctDNA somatic variants with ensemble machine learning models</a>  <font color="#6f6f6f">Nature</font>

Distinct mutation accumulation rates among tissues determine the variation in cancer risk
Naturegeneral

Distinct mutation accumulation rates among tissues determine the variation in cancer risk

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE9LSExKWTZTYW5IMGFPN2FfTmtoTVVYOE5YQUk0YTVMSThDVHRYRWZoTnpJTE0yUXotTUFta3MxMS1EdlhpdlI5aXRaYVJyWDhWQnJr?oc=5" target="_blank">Distinct mutation accumulation rates among tissues determine the variation in cancer risk</a>  <font color="#6f6f6f">Nature</font>

Lymphoid clonal hematopoiesis: implications for malignancy, immunity, and treatment | Blood Cancer Journal
Natureworld

Lymphoid clonal hematopoiesis: implications for malignancy, immunity, and treatment | Blood Cancer Journal

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA0YnMyOWFsTWdRRmNENk9wbHNLNTAtSTNsYXY5elJEWUFhZjdtdG94QkhKUEhCMlh0Y1l0ZW84MlBZZzdkdjlEUVJzbm5jQWlvNHhDckpmNXV3c3ViTEww?oc=5" target="_blank">Lymphoid clonal hematopoiesis: implications for malignancy, immunity, and treatment | Blood Cancer Journal</a>  <font color="#6f6f6f">Nature</font>

Distinct mutational backgrounds and clonal architectures implicated prognostic discrepancies in small-cell carcinomas of the esophagus and lung
Natureworld

Distinct mutational backgrounds and clonal architectures implicated prognostic discrepancies in small-cell carcinomas of the esophagus and lung

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1saXJLZGloUW1kNUkwdE40RE9KS0FIZmtfSWVidjBiclJkU1JUeWpBZDNXcFowMngzRkRpRkhfQzhJSGd3Z1BsRFZnNzRWWEtHYmVSNDJIc0JPeWhjM2tB?oc=5" target="_blank">Distinct mutational backgrounds and clonal architectures implicated prognostic discrepancies in small-cell carcinomas of the esophagus and lung</a>  <font color="#6f6f6f">Nature</font>

Distinct molecular profiles drive multifaceted characteristics of colorectal cancer metastatic seeds
Rockefeller University Pressgeneral

Distinct molecular profiles drive multifaceted characteristics of colorectal cancer metastatic seeds

<a href="https://news.google.com/rss/articles/CBMiowFBVV95cUxQZ3I0am5mNkRMN3p1VXlQUWcyMWNfS2tZMGN2eU41RFNwZGplMWRDRnJxQnBfNHFWclF6enZESUpxU1psN05nSHNrUnVWTlhwZkNxX2s1RUdTMEdyM0w2d0ZfYThWVklkYjc5enZzZUtBV1dlV05WNkhTWmw2akp2c2ZUd1hPZG1oYTMyR0tzUUJSTGVwVXJ2RXJYUWZTUm9CUjhZ?oc=5" target="_blank">Distinct molecular profiles drive multifaceted characteristics of colorectal cancer metastatic seeds</a>  <font color="#6f6f6f">Rockefeller University Press</font>

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
Natureworld

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE50OVR5R182WnZ4SFQ5aDRSQjdKaFVxb054VHhUeVdNalgyYTlhT05Bb29PRXpxbnh0Y2tWQ1FhczAydng1NTF1YThOa1I4bU9NUDNjUE9B?oc=5" target="_blank">Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets</a>  <font color="#6f6f6f">Nature</font>

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract
Wiley Online Librarygeneral

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract

<a href="https://news.google.com/rss/articles/CBMia0FVX3lxTFBhU2M5QmhGUF9aQTZiZWs5NExmNm1RUTB2ZnNtU29EZ3RpSG91dTB4NzNXRjh1VnNjczJZMW8tUFJidGJYaTJxMDFfVzZCZ2lVM0dhcm5rZWdVTkEyLWRlSjR6U2xXOVplZmxZ?oc=5" target="_blank">Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract</a>  <font color="#6f6f6f">Wiley Online Library</font>

Thyroid nodules with DICER1 mutation or PTEN alteration: A comparative cytologic, clinical, and molecular study of 117 FNA cases
Wiley & Sonsgeneral

Thyroid nodules with DICER1 mutation or PTEN alteration: A comparative cytologic, clinical, and molecular study of 117 FNA cases

<a href="https://news.google.com/rss/articles/CBMie0FVX3lxTE1QRm1pVmRDbzhEWDEwSGRSVXNySHg4WVVOVk1mcEw0S1RWdU5kb1JFRTI0MzhBZjkyYmtpRURIMUdDT1pjTGpVWFVHTXFOc2JzODd1QUVBX0NONDVPTWlUM0tseV9vOTRYaU5nOW5WWnU3UG94T2hVRDRKYw?oc=5" target="_blank">Thyroid nodules with DICER1 mutation or PTEN alteration: A comparative cytologic, clinical, and molecular study of 117 FNA cases</a>  <font color="#6f6f6f">Wiley & Sons</font>

Clonal selection confers distinct evolutionary trajectories in BRAF -driven cancers
Naturepolitics

Clonal selection confers distinct evolutionary trajectories in BRAF -driven cancers

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5CS01WU0lETVhjWVRoREZFVGt0TFNiRnpza2VyRzB4QTRiTURmZXVNRUFySmJkNGV3S0NlRjFNMHpibkh0TWt2YXU3MUZERXJjNXNsNk9ac1IyTFRGSEJN?oc=5" target="_blank">Clonal selection confers distinct evolutionary trajectories in BRAF -driven cancers</a>  <font color="#6f6f6f">Nature</font>

Divergent mutational processes distinguish hypoxic and normoxic tumours
Naturegeneral

Divergent mutational processes distinguish hypoxic and normoxic tumours

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1FSFItY1FnNTNJQUhKZU5JWno2bFRrUHo2dUhIbWpIRVhZaGVpeUN6U3VnWFROcHpRTkxKcUJtWDQtMHMtLU1OSlUwRTY0UlVqUnRkX0RXdERWdjFrWE1F?oc=5" target="_blank">Divergent mutational processes distinguish hypoxic and normoxic tumours</a>  <font color="#6f6f6f">Nature</font>

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