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<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAyb09vM3B4NDNyNFVfSzhlLTFNTDZkTkxCZ0lLVmVJWnFnNkhfenN0MjByNl84V1oyQjZVbU4zUk1PX3Q1b2FXYVVXUmJWZldwS0I5MjBGYkF0Y01wOS00?oc=5" target="_blank">Small-molecule binding-site discovery using silyl ether-enabled chemoproteomics</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
Selma Blair arrested for biting flight attendant, trying to open plane door
Al Nassr Asian Champions League clash in doubt over Riyadh security situation
Kyle Busch’s Widow Samantha Calls His Death ‘Unfair’ After ‘Emotional’ Celebration for Beloved NASCAR Star
Minnesota Poll: Flanagan holds narrow lead over Tafoya in U.S. Senate race
Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News
<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE9ldGN4VmFDSWY0RmFNNUVKX3FhZktrZGY1aTJLdmJpUkZhTVdWSGV1YVVoS0JrTkdIcGZHd0xDWG9RdmZHUzM3Q1F5eDBvQWRoMWRCUmFlMVV1NTRO?oc=5" target="_blank">Unified protein–small molecule graph neural networks for binding site prediction</a>&nbsp;&nbsp;<font color="#6f6f6f">PNAS</font>
<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTFA0clZmaVFTcjQtbWtWZ2pGNko3TDFGNllRVjZQQnFqLUdWM3llSzVRS1F5dGRVdW5Vck9iVk9DUTItZ2RqV19iUlpnakg3TFVvR0lTVVZUQXRKNDVobGw4aw?oc=5" target="_blank">De novo design of small molecule–regulated protein oligomers</a>&nbsp;&nbsp;<font color="#6f6f6f">Science | AAAS</font>
<a href="https://news.google.com/rss/articles/CBMiZ0FVX3lxTE03VWJCRUlNdVRucU8tdFE0YWloSEtRdEFZdkdyS2FCdHA0SE5wd3BTMFlBTHVVS1R6RHo3UDRoN0ppTWJPRE5iWVFPaXdxQUFRako0M1BqVjY1S0wzY3FhMnRIS1pNWTQ?oc=5" target="_blank">SOLiD-MaP: A Photoproximity Labeling Platform for Small Molecule Binding Site Mapping on RNA</a>&nbsp;&nbsp;<font color="#6f6f6f">Wiley Online Library</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5RWkllX1RNQTIzaWNnRng4aUJiT1pZaHdnY3pSZXEtT2lENC1pLW5sd2F5Z1M4WUMzbmxfYkhCY0VyazlNeW9rTzBCRGxseHQ0QjRsblo5ZDFKR3pXNHJN?oc=5" target="_blank">Small-molecule binding and sensing with a designed protein family</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMi0wFBVV95cUxQR0NkdnF2WU9wY2NPVlBtS2FZQWI5MktTc3VkUmM3YVItNEJSSlBfYXdsbWh3VXRWTXFiZEZPUm1XOWJPbFp6NjRRay1SeXRhWUx3enJBeGZ6aTE3R2xIbEZNQ1dLQjF5eER4R0poMm0yNEN1Qi13WGxBckFWOVRvOUk4UkZ3NHBTUVAzYWp3Mzk1c1VUUzFab3RFczduLW5FeEJIR2QydFVHMUtzenJBMVZnSGw4UEJsVVhUdGNNWi1nZGc5NUhTOFRyUG1PLWstU3pR?oc=5" target="_blank">AI tool dramatically reduces computing power needed to find protein-binding molecules</a>&nbsp;&nbsp;<font color="#6f6f6f">Chemistry World</font>
<a href="https://news.google.com/rss/articles/CBMilwFBVV95cUxOVGxnbWJZZUpzbXJLcUtPcGFYaE1sUEFXMGdPQWxfVGFXWmg2dng3MkduR1dNX0hyMkhsb2E1aE9jdDA0alR2NUF3Rmh2ekpWS18xOHBDYWFCRDRtaXd2bDlXbGNKZ1ZFT0ZxbGZMcExjLU5RcDFJNmNKV3ZrY2dET3VoeVRWVVRoZ1BIbno4N2w0Nld0bEk0?oc=5" target="_blank">UCLA research improves molecular probe for drug discovery</a>&nbsp;&nbsp;<font color="#6f6f6f">Newsroom | UCLA</font>
<a href="https://news.google.com/rss/articles/CBMitAFBVV95cUxNOFAxaFc3OUk0RDBFQ1JGek5pdjVtS05nNXZ4M0NlZi14Y2xTa1VJTzNQODVPYy1lRmUzVlo1T3dkeGtQZGh5WHhUQUltR2xEM2gxUUNDbzAyZ1FtV2RmQVQ0dXVSN0VvOUIwT2lmcGVESnZua1o4VWRWV3VUREl5bzkyNlVvV1ZRX2xHSnY0RGZqR01QaEdwaHNYMFhqTTU1bnZQTXJCSEtuaFNmVElEeXFYYzU?oc=5" target="_blank">RNA-targeting small molecules: a new frontier of drug discovery</a>&nbsp;&nbsp;<font color="#6f6f6f">Pharmaceutical Technology</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4wQWZXLWp0LVhJMFUxZ1llYVB6Vm1sMWN6TzBSRVZCNjVXOVZMN3lGRUNpeWl1Ym9aUl9HMkI1NXVJUDFOX3BsV043VGFPOVd5aVdJNUxfOHlPZU1fWVhr?oc=5" target="_blank">AF2BIND: predicting small-molecule binding sites using the pair representation of AlphaFold2</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiYkFVX3lxTE82bG1aNVAzN3RPZ2tXTEZjWGtHOGpNWmFIS281UllZNjBiS0duRzN0SEg5bjBDSWlNVHBxY3BKdlpxbVhBdGVzOUJJcnAwdmpFUUlhdlRycHFvb0R3cnBzdmZR?oc=5" target="_blank">Canonical EDS1/PAD4 small-molecule binding sites are required for LRR-RP-mediated pattern-triggered immunity</a>&nbsp;&nbsp;<font color="#6f6f6f">PNAS</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1OOUxjOGItQlVRQVl0dzlZZHFISU9HaG1OS2s4cFpndmhYcUdHVmVndEFKU0FFU1ZtcXhOa29USlRONndEMUxWVzZLVUtzOURmVFNpZGk2MmpkcnJOcHFz?oc=5" target="_blank">Zero-shot design of drug-binding proteins via neural iterative selection−expansion</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBhMl9kTlQ4ZFY0ZmRFWGlLTzJMQzkwY2k3THhOOU1zOGtCRndGeW4tN0lCSGJUUWxJTVFjYk5uN0VRRkkwSEoxTWRJYXNrSEhPUDVlMGFxQnJlZUVLaFJj?oc=5" target="_blank">Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ST2ZwekRJcVdqYXk2dFFSZUg3d3IwY3dJREQtOUtTc1NVLURSWXcyUGFTTDBTZjEyR3oyZGVWam16UVVybUhneXlDZU9yUmhKTGc0OGFtaHlVZnE3Z19Z?oc=5" target="_blank">Molecular driving force of a small molecule-induced protein disorder-order transition</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5KWlduZWtJN1dwaUZ1LVVrWE41SFk3TU9CZUdJVXJ0amxvcHJZNmtKQzdobzM0ckJDbE8tVXpGbjRmeWlwMzRQbml6dlo1X1FSMU1NbzF6TWNXTFdKd3Yw?oc=5" target="_blank">Systematic identification of variant-specific RNA structure-small molecule interactions exemplified by RNA G-quadruplexes</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE83NV9oTGZkT1luSFZfR3dPaW9YcU5sUThNODhzalRyREJVdWRSVzJSaUtMTXl2YlNyLUlfcFdfR0pKQi1Jdm1TMF9oTHFkOUI5em5ORkhNS1RObndCcHJB?oc=5" target="_blank">Structure-based virtual screening identifies novel small-molecule inhibitors targeting the endonuclease active site of APE1</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8yMXRUMV9waWh1UkZudnJtNldWQ2xMa0V2enlKS21GTnZYZXoyR1I4SHV6MzRaeVhFRWxHOElLa1lXMGg0ZlJPNHB0WTFtbGl4Qnh1SE1TbTQ3ZEtiTmxR?oc=5" target="_blank">In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBJUXJtelZsTVNBaTRlb2thYUJKZkxYX25nRkZGUkVaVHQ5MHJ3MVFtaWcteTJQSFhSZFktMnZmRzA3eEtLWGtRN1lGUjBBQndkNVFtOHFtTVNfT0NJZkdz?oc=5" target="_blank">Small-molecule modulation of β-arrestins</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9hUmN3MzFMeVB6VnY1Wl9YdzRoQlJ4YjhSdzAwVTVNT2FYaE0xYXBtZjl5eGJuemdVa3RwMTZjVV9UX0tKdDJPQnJ0b2hGT3hYelM4dVBNanVaX2U0UTlJ?oc=5" target="_blank">In Silico identification of inhalable small-molecule IL-33/ST2 antagonists for severe type-2-high asthma endotypes</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5GVkUtQlgycVZCaWplT2NBajlsVUZuOG5LM0ZhS2ZVcTJOU0p6XzMyNERtS0o2cDhHMjhFVHBBZlp4bVd6UE1CaTlnN3lka1ZjaGsyMFpmSUNfaWpjZXhr?oc=5" target="_blank">Discovery of thiadiazole-based small-molecule inhibitors of SARS-CoV-2 spike-ACE2 interaction through integrated computational prediction and experimental validation</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMioAFBVV95cUxPU296dUFFeWl2UlJ2ZmwyTzBxbThBc1FhQ3ZBdDc3N2Z0ZzZwOVMyZWZ2U2k3NDVLYTVPcEhmekJXLWtoc0hvbFg3Y241WGRxLWNIci15eHFfaTRjMmtkUmRWQXlBel9DNnBtSkxQNEh1dWpKaHo0WEF0dGJseWJiMUZORWdfRllkMzRhT181ZUNmdVVKU1ZxWExqM0d2SGxO?oc=5" target="_blank">RNP interfaces as regulatory “active sites”: a repurposing strategy for small molecules targeting viral 5′-untranslated regions</a>&nbsp;&nbsp;<font color="#6f6f6f">Frontiers</font>
<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTFBadE5adGx5MGNuS0pqTFlDZFdHZXUzTHQ2RUhoSk53a1FTRENZUkNqVzE1M1UyQmY1aHRMRDZhNzVUZWRvbENpdFdORmx3UGtjdTNB?oc=5" target="_blank">AI-Driven De Novo Design of Diverse Small Molecule-Binding Proteins: Korean Team Finds Proteins to Selectively Recognize Stress Hormones</a>&nbsp;&nbsp;<font color="#6f6f6f">36Kr</font>
<a href="https://news.google.com/rss/articles/CBMigAFBVV95cUxOY28zbUFKbE1XcTRqdWxzNy0zazBNbVpzWjl3ZGZlVXY2Smh3NDBfQ2k5STE0WGVOUXRGcXpWcGVza0wxZTlnSUFJay1lTUtDSm1YZmpsV2lsZEY3NGdmbmxOSUpVdnBYNmRWUnpkUF9KUEcwdDF5dklzbi0wZVdMSg?oc=5" target="_blank">Targeting RNA with small molecules</a>&nbsp;&nbsp;<font color="#6f6f6f">News-Medical</font>
<a href="https://news.google.com/rss/articles/CBMioAFBVV95cUxQWjdzbTVQSTd3eW5ORC1wU29YNVMyNG9tX0tXUVJscXNYQTNZUnpiQzNtVmoyeXRYWWpRYmpVZlh6d0JkWHFPM3hLRXlxRUhINTJHdWRkQjhITnNIOUlJa0xxS3M2NWx2YXV1YUJrUFRBaTFLd2JsOWQ2V3kwVjFUM256QVpfdTBUbENkc2ZEaGFGcE40dXIzaHJyV0gtZld1?oc=5" target="_blank">Accelerating small molecule discovery for RNA drug targets</a>&nbsp;&nbsp;<font color="#6f6f6f">News-Medical</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBIamxlYVZJald3N0xlU2tzb3JLODk5SlNTNzk3QWdiVWotZWY1MlpXcHR1aFVtLW5oeEdETWswLWpYWnRkMkFUTWNhVnNmZXNyQnNpMFozak80d1paRF9Z?oc=5" target="_blank">Enhanced mapping of small-molecule binding sites in cells</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiowFBVV95cUxPSXZNRzRzYzYxTUdrcllZMjFxMnMxZkduWjVPQTEySEpmTXZKX01md1FPXzViQXd2aDRWdmpqUElnVVkzUFc1cExFb2JyQ2R1TFlpVHlObjU5V2ZkT3RNbzNPVE9uZ2tmNlRXaGROc3d0TzU0Ql9iMGMzNjFxR01WMDJoSXh1SzB5YW01Nk8yVjhvMlFuMUhhNjNtLWtMb042U2g0?oc=5" target="_blank">The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold</a>&nbsp;&nbsp;<font color="#6f6f6f">Isomorphic Labs</font>
<a href="https://news.google.com/rss/articles/CBMilgFBVV95cUxPTWQ4THBzZ3h5bWpXQVRGeUlDb0NYaTcxYWlYcm1TMTk4c1htR1o4RWpzLUFzVmFjWEt3Smc5NXBHZGVaWXVObURoQXdHeGs1aTl4cTNUTUdfUXpPZjZFSmhsc2k0YnI5OHllX0VNTmg3TjJSSEhXN2JTWUliT2lpeVl2TWhGSHRGU0RZV3BvcjBaaWY3QUE?oc=5" target="_blank">Discovering Small-Molecule Targets via Silyl Ether Chemoproteomics</a>&nbsp;&nbsp;<font color="#6f6f6f">Bioengineer.org</font>
<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE1YZFRReHlCOTRhbVM4M3FsYUtCSkZGOUQ3bmlkbkl0czhYUm93SDlMUElFRGN2dHZzaEFDcVlwS3EzVUduVTBjaW9uVDdSZTBlb0t4LTFzOVR2R3RuNUExMg?oc=5" target="_blank">Binding to RNA is not enough—changing its shape is what makes a drug work, study reveals</a>&nbsp;&nbsp;<font color="#6f6f6f">Phys.org</font>
<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE1DQ0VXZDRORlZILTFYNWlLeEZ0Q1B6X3hsNk8wSERpTnRicDhDRjhNVm5Da09rVVBRM3VxY1ZFa0I0cFJ0YWh2cWhuUFg4aG80Y21XQjVTZVVTLWhZcHBGYw?oc=5" target="_blank">Binding and sensing diverse small molecules using shape-complementary pseudocycles</a>&nbsp;&nbsp;<font color="#6f6f6f">Science | AAAS</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9vR05adXhpNzVsdmN5RGd5cW43UWpueVJNVXlYd2llUnlZZWxSR0NJSkhScTlPN2FlMEFkVUFoaEQ2MWZuMDNpNFRKU1JHQlhlVnJkLVVWTWs5M3VFc0pZ?oc=5" target="_blank">Predicting the binding residues of four small molecule ligands by utilizing ensemble algorithms with additional correlation features</a>&nbsp;&nbsp;<font color="#6f6f6f">Nature</font>
<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9DLTU4bEtGNXZ0WV8wS0YycEZsakVWZ2VBSWJGdEJRelhHSDBmYVlfYmlUYjhwNzV4UkpueHplQ0tsMlNNQXpacG43TE5KNE5HbkpRaXhJbFJRVlhzdzFR?oc=5" target="_blank">Qiangfeng Cliff Zhang and collaborators achieve breakthrough: Predicting small molecule–RNA interactions without RNA tertiary structures-Tsinghua University</a>&nbsp;&nbsp;<font color="#6f6f6f">清华大学</font>