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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Single-nucleus DNA sequen" (30 stories)

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Single-nucleus DNA sequencing delves into the varied genomic evolution of pancreatic cancer
Lead StoryNaturegeneral
Feb 2

Single-nucleus DNA sequencing delves into the varied genomic evolution of pancreatic cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5rQjJodnEyR0k3blVGcVMtVHViUDNWbEZYUng5ZWwzTmN5dFdTSUIwN2ZMY2kxSnhXU3pLSnQxTEFRUnNHTEgyNjQ4dmpkaEVWM0gtRXIybHRsU0QtZlpj?oc=5" target="_blank">Single-nucleus DNA sequencing delves into the varied genomic evolution of pancreatic cancer</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Single-nucleus DNA sequen"

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29 stories displayed
Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation
Naturegeneral

Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9ibXo2TjJxNzB0c2JsZTM5ajUzRmdnRTJhNVY0TGJkdERGVnFuZFpMYm4yaUNNYnh3dE9XN0liOUViejBadWEyY2MyWl8zM1pRdENJREZ4REhxa1ZpcWVv?oc=5" target="_blank">Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation</a>  <font color="#6f6f6f">Nature</font>

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Genomic evolution of pancreatic cancer at single-cell resolution
Naturegeneral

Genomic evolution of pancreatic cancer at single-cell resolution

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1FckR5c0s5b2RwdmZ2SlhwLUZ2Z3Z2cjFkaVZzTmNRNHhfbnNpeVdlazFJT1hDdUNJbkp0QmRHbGlOSHdfVGFTTWd2WGhBcUQyVnFWWDY3enZIQWUtQ3lr?oc=5" target="_blank">Genomic evolution of pancreatic cancer at single-cell resolution</a>  <font color="#6f6f6f">Nature</font>

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Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
Science | AAASgeneral

Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE8wbmdIUGRfbFVQNW43X1NEd0Zzb2U4ckFnTVpnZ1FyeFdCV0d3N1N4RS1QYzF1ZXpHaU1sY0I0ZDRvbkVWUFRjbVcyWGVndG05bGhWdmd5dFRiaFIzUmx3NA?oc=5" target="_blank">Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation</a>  <font color="#6f6f6f">Science | AAAS</font>

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Integrating single-nucleus barcoding with spatial transcriptomics via Stamp-seq to reveal immunotherapy response-enhancing functional modules in NSCLC | Cell Discovery
Natureworld

Integrating single-nucleus barcoding with spatial transcriptomics via Stamp-seq to reveal immunotherapy response-enhancing functional modules in NSCLC | Cell Discovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBoY3Y2MV90R2NfRWxLelNJT3VhLWk2TnNkT0QwZkxWdmRwaUlZUGozNEEyYWlSY1dRbk1mSEUtblByMjJsdjJvbnpNSTAwaFd4WFhXLWtCM0M2Nm9ScGVV?oc=5" target="_blank">Integrating single-nucleus barcoding with spatial transcriptomics via Stamp-seq to reveal immunotherapy response-enhancing functional modules in NSCLC | Cell Discovery</a>  <font color="#6f6f6f">Nature</font>

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scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors
Science | AAASgeneral

scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1HZ0R3OEU3eXRvdzdZTTdHRVQyUHRCMHViS3VoMzB4MUE0MFlyTkdKXzJISjJXTHpSSVhDRkR2WXVtMXJCa1VFd3h3TEJRdmdOYUtEQ0pUQkF6ZTFWZ0ZR?oc=5" target="_blank">scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors</a>  <font color="#6f6f6f">Science | AAAS</font>

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Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs
Natureworld

Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5Vbjl0YURYMzNxSnI5RUxhMjdxdGE1aW1nM01kYW5ZTHlOYUIxRW15N1JVNi13QWdveUtobnZEcG5kOVJWZEZHNVlzbG8yRVg5RWZZcVI0TC1kV3ZndTF3?oc=5" target="_blank">Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs</a>  <font color="#6f6f6f">Nature</font>

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Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer
Naturegeneral

Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBYTUFPS0NqVlBrYVhHbHVQRDh3WFNjYU4tRGpNeWhzUGE0V2UyckVwemdsb3F2M2JlcEhnb1QxcHJkS0h4S2R5Q0VmWlRsWFJBTkZoRENlUmpoSVVsRzVN?oc=5" target="_blank">Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer</a>  <font color="#6f6f6f">Nature</font>

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An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics
Naturegeneral

An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBEUGdWQ09MTlFSTmxqajBZV2ZmX0hsS04zM2xfUGE0a2JrUDFrTjVrbl9rR05TQnZYSzBJRWhBbFdaVTFSeG9WUFpLYll1Q3lUMWF2ZjFiZWpwY1cxRVBn?oc=5" target="_blank">An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics</a>  <font color="#6f6f6f">Nature</font>

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Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations
Naturegeneral

Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE11RUtLT01temVMbUFtMjZGbmlrb1hyQ3llUndRVkN0Y1pLeld3NnhoaExsbnpiZGxzdG83dnNPOVU0ZHRDRUtqMEw2Rk10ZS1JQ01RLTRnbEVsOHVVSU9n?oc=5" target="_blank">Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations</a>  <font color="#6f6f6f">Nature</font>

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Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
Naturegeneral

Slide-tags enables single-nucleus barcoding for multimodal spatial genomics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE90OFJGdU9fUHhUTjdXN3JSNk5HQ2lCbFZXLXdVQ0g4WVpfX0xnOG13YXpjRmZybnU5aHl3OWxxWnRvMUxjQmdZVUwycVJXbU5PRkI2X216dEJwbFRBWWpz?oc=5" target="_blank">Slide-tags enables single-nucleus barcoding for multimodal spatial genomics</a>  <font color="#6f6f6f">Nature</font>

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A simplified preparation method for single-nucleus RNA-sequencing using long-term frozen brain tumor tissues
Naturetech

A simplified preparation method for single-nucleus RNA-sequencing using long-term frozen brain tumor tissues

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1UU0ZzVmNNeUszU3dTUjRxZmplWWpVXzVLRlQ2cXBHUXI0SHlxbjFRQmFoMTJNandmSHlPOTlQcWJ3ZWxSc0phcUN4T1JtUkNrQXgtRXgwa1U4akRyQW9v?oc=5" target="_blank">A simplified preparation method for single-nucleus RNA-sequencing using long-term frozen brain tumor tissues</a>  <font color="#6f6f6f">Nature</font>

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High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq
Naturegeneral

High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPZHhsQUcxQkFselp4aHNUcDhLYkZuaUZvOFBwZncwM1dkRC15THJqR0o1eDBuZXhmaEhVdTVJS05QbTdaLXIyZHBtWnJOalozekdiQW1Yak9FWXBXdkdR?oc=5" target="_blank">High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq</a>  <font color="#6f6f6f">Nature</font>

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Single cell long read whole genome sequencing reveals somatic transposon activity in human brain
Naturetech

Single cell long read whole genome sequencing reveals somatic transposon activity in human brain

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPZmVFWmNFc0FaN2RSWHAxU19wMFJWMFlValh0bHdVaU0zTkxJeFVqRGxKQzczMG82Nnl1eWRPeEZfMW9sN01QN1d5azU3ZURNOGkzYmlIc0xPUWp5TkpN?oc=5" target="_blank">Single cell long read whole genome sequencing reveals somatic transposon activity in human brain</a>  <font color="#6f6f6f">Nature</font>

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Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain
Naturetech

Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1DYS0wMlJRNWRDdE02UjlZX0NVX2hNWncxdTM4ekVhTGlIRUt2R09aVDNjRWhjWkI3cUtORFJTT0FGS0VjVG00S1RHVUVlSEc2b0l6YV9ycVZveG56eVJv?oc=5" target="_blank">Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain</a>  <font color="#6f6f6f">Nature</font>

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Single-nucleus sequencing dissects the malignant change of early lung adenocarcinoma: SMAD3 suppresses antitumor T cell immunity via ICAM1
Natureworld

Single-nucleus sequencing dissects the malignant change of early lung adenocarcinoma: SMAD3 suppresses antitumor T cell immunity via ICAM1

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE04QkprSlFiTlItWk1oaHBvV1Z5ZlhOdlliUHdmNzB5S3EtWklzY1ZodXRyQnU3cDk2YU4zRWEwcWhjc1Nlcll3VmR1VUVwVWN5QUtyZ2VjdFl5QmtHeTMw?oc=5" target="_blank">Single-nucleus sequencing dissects the malignant change of early lung adenocarcinoma: SMAD3 suppresses antitumor T cell immunity via ICAM1</a>  <font color="#6f6f6f">Nature</font>

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Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics
Naturegeneral

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9VS0lfUU5mMWNuSmhfSmNtbnJjYkRCOXUxcndnR0cxYjN0bmY1SHlHUnJiMFJRM1dydTBEcGRMQW1YbDNjaWlfN2dISWhjUHB1RFF6VHc1VkQwQWptWlgw?oc=5" target="_blank">Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics</a>  <font color="#6f6f6f">Nature</font>

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Single-cell nascent RNA sequencing unveils coordinated global transcription
Natureworld

Single-cell nascent RNA sequencing unveils coordinated global transcription

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5CSDZyeUF0VEJSY3RZUkx2SnFLNE1yT05IcmtqaVhjbmVKbWtYV0tNcHlzZ3dtakdHaC1fSUY4d01MUElLMDdvdzZCTk45dVN5THFnb0gxaHVjNTBJdndF?oc=5" target="_blank">Single-cell nascent RNA sequencing unveils coordinated global transcription</a>  <font color="#6f6f6f">Nature</font>

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Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia
Naturetech

Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5EZEYtWWVUaGpNeDRFdm9LT21fTG5ER211VUt6THZWS3RjQVdCUDZJdHpCaGFrRDBEanZkMmZ2c3lHcHJCUkVaT3dXQUpUQm5VSWd5QWoyRlQwVkcyMVZn?oc=5" target="_blank">Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia</a>  <font color="#6f6f6f">Nature</font>

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A versatile and efficient method to isolate nuclei from low-input cryopreserved tissues for single-nuclei transcriptomics
Naturegeneral

A versatile and efficient method to isolate nuclei from low-input cryopreserved tissues for single-nuclei transcriptomics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ISGZpLVNDa2JXN01MN2hSNHJRUUZLdGtqMnRrZTNJenJxMGdKWVg0amVRN01Eb0JaQUdNZUFhUllLalYySkZoMWRCbkpLTHQ5akVhVENXNTU0cFFNcV8w?oc=5" target="_blank">A versatile and efficient method to isolate nuclei from low-input cryopreserved tissues for single-nuclei transcriptomics</a>  <font color="#6f6f6f">Nature</font>

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The multilayered transcriptional architecture of glioblastoma ecosystems
Naturegeneral

The multilayered transcriptional architecture of glioblastoma ecosystems

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5aNDlCa2x3X3JlNWxQSmNNT2xLZ0I0YmI5Y3NUeWhCbG9wUEJfcGgtcmRfWWhwRWFyWWpTZndxZ2ZmNlJvZURmQnMzWWMta2tvWkUxQVBIdUdFSmNYN1hZ?oc=5" target="_blank">The multilayered transcriptional architecture of glioblastoma ecosystems</a>  <font color="#6f6f6f">Nature</font>

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Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue
Naturegeneral

Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB3WnJyb1pDZy1jTzZfUHBTMmdzeHFEenBOQXBYVUpSU21pMmoxZzNVYkV0cHpuVERyQml4czhwMkgyVHdGVk5JbjQ5czRpNVVBQk1Eb1VYUm9lV3RJc0tV?oc=5" target="_blank">Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue</a>  <font color="#6f6f6f">Nature</font>

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Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance
Naturetech

Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE41RUphQjd5OFJRM1lVTTdvb2s4TU9FeGhEZmJ1UnFNNnh4SFpNYzN5eHNmaG5wdHhCblhYaGcxdFpNRlVuMFFpdk1RTWZkeHQzMFZmbm80eHRDbWQ5VFJF?oc=5" target="_blank">Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance</a>  <font color="#6f6f6f">Nature</font>

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Nuclei multiplexing with barcoded antibodies for single-nucleus genomics
Naturegeneral

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ZRmgwQnVCTVgwczRQbnZZSmtMc3R1SDVpMnNfcHRXSW16ZThXclpnVDFlOWFLUVhxZTJNWHE5Y3hlOGl6dzRZTTNlT2RXUnp6Tm5oZzVCaEl0eVlfZFhn?oc=5" target="_blank">Nuclei multiplexing with barcoded antibodies for single-nucleus genomics</a>  <font color="#6f6f6f">Nature</font>

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Single nucleus sequencing reveals spermatid chromosome fragmentation as a possible cause of maize haploid induction
Naturetech

Single nucleus sequencing reveals spermatid chromosome fragmentation as a possible cause of maize haploid induction

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE81Nmh4a1JaYVNLNTB5eVhnQS1mSnhKX0Q3bGEwS0xOeUNpMzBEZmhVLWQ0NFZUb2I3OXFjQXBVdm4wVkVRbG40Q3FkVHVNWktIbFFyU0IyUWc2T3lIRG5B?oc=5" target="_blank">Single nucleus sequencing reveals spermatid chromosome fragmentation as a possible cause of maize haploid induction</a>  <font color="#6f6f6f">Nature</font>

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Transcriptional linkage analysis with in vivo AAV-Perturb-seq
Naturegeneral

Transcriptional linkage analysis with in vivo AAV-Perturb-seq

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBYZFdEdEFXYnoydnZ1d3dYRkFVS2RKVFd5VURuUjB6N3Zjd2tCdzhhYy1Xc0cxWTNzVGRtUXp2VW1TTGxhLW9wYkRsa0FSOTNaczFSZWVremhGMG84WEln?oc=5" target="_blank">Transcriptional linkage analysis with in vivo AAV-Perturb-seq</a>  <font color="#6f6f6f">Nature</font>

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Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes
Naturegeneral

Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1CVmVzX3ZNckFScVZOalBCRHhsWXctRFZ0aWlWNHJ4ejVTWDdwdzlZbFNxRk1UbHg5TWpnb1JHUzJUb2Exa2haR09vNXNzSkN4bFZKczREbFBXS3dWVk84?oc=5" target="_blank">Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes</a>  <font color="#6f6f6f">Nature</font>

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Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes
Naturegeneral

Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ka20wUUlJbG9EMVFaaDROZ3cxQkx1RGRLN09ZLWNlR1c3Z2xRcjVZVkstZUJkTHI2UjFZSnV1Z2lGazlVX00zM3IxbjNBZ01CM2FlbWxISG5uYUpWTlJn?oc=5" target="_blank">Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes</a>  <font color="#6f6f6f">Nature</font>

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High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors
Naturegeneral

High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1nMGs3MlA1ZXBvNWc3VkVVb0syNWFNdXVrbEZtaTNHUkhzRTYwUnBuV3ZNQ3UtX3ZxNXY4OENIbFBDN1hEa2x0MW9WS0tmUjhQc1Q0WUpxb0dCODNidGlR?oc=5" target="_blank">High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors</a>  <font color="#6f6f6f">Nature</font>

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Single-cell transcriptomic and genomic changes in the ageing human brain
Naturetech

Single-cell transcriptomic and genomic changes in the ageing human brain

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4tTkxuaENKakdvV1Q0UE5wSV80SkZyVmV2a29pZ2VXNHNPUVhvRnZpckVvQWpTWEo3ZmhVRnZKVFl6aXVYTDhCdUVpMHNIZURFbEl2N2NBM2ZFX2laR3Fr?oc=5" target="_blank">Single-cell transcriptomic and genomic changes in the ageing human brain</a>  <font color="#6f6f6f">Nature</font>

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