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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Signaling Drives Mitochon" (30 stories)

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Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging
Lead StoryNaturegeneral
Aug 28

Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4xaGUxS0ZaeW5uUWRVX0lpb0NkZXRBUEdXRjg2TGIxcE1NdGNWOENJanVDcWsxRERDWGRZZ054VkRvNHJSa09sTUlOcENCNHByQXVjTFR2aTRoX3J1eUU4?oc=5" target="_blank">Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Signaling Drives Mitochon"

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29 stories displayed
Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats
American Heart Association Journalsworld

Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats

<a href="https://news.google.com/rss/articles/CBMic0FVX3lxTFA2cUhNVGRJa2VhWHpMM0hDN09Ya3RaeWl5YjBvQjRkZGxtOGFIMl9IdS16ZlVmQ1pqVncxeVA4VHJXNGdHVk5hWC13RWRycC10QTdCeVFjcTYwbzQtOE11NExzRjNCYXo2S21wOXJUZjZyQlk?oc=5" target="_blank">Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats</a>  <font color="#6f6f6f">American Heart Association Journals</font>

The mitochondrial logic of inflammaging: how energy imbalance drives fibroblast SASP and tissue-specific aging
Frontiersgeneral

The mitochondrial logic of inflammaging: how energy imbalance drives fibroblast SASP and tissue-specific aging

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPMi03enVBcmk3d0oxTjF4QlRJb21wcS1RbDhELTgySmhCYk01Y1VUMkVkclBmTlpMX19ZVExqOFl4dHZLb3VIQk13Smx6Qy1WaDA1ZGhrcm1FdzNuRnlMVHUzbG9hdThiaWVnaUphLUlCREw4QTJSeDdsVy1odWNzT3lFUFFJWVdiMnNWY2VYc0JuQQ?oc=5" target="_blank">The mitochondrial logic of inflammaging: how energy imbalance drives fibroblast SASP and tissue-specific aging</a>  <font color="#6f6f6f">Frontiers</font>

Nitrate-Sialin2 axis couples ER-mitochondrial calcium signaling with fatty acid metabolism to drive white adipose browning
Naturegeneral

Nitrate-Sialin2 axis couples ER-mitochondrial calcium signaling with fatty acid metabolism to drive white adipose browning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE91QV9RMEktSG9WdEoyR3ZYUTRZRk50TmlHTzVUbFFiWC1JeXpDZmxYNjFyRkNYWWdXTTliZ1hFTmxHZDVMWEVtZHE1Z1JfSjNIZTB6RzhsbE5hdU80SUs0?oc=5" target="_blank">Nitrate-Sialin2 axis couples ER-mitochondrial calcium signaling with fatty acid metabolism to drive white adipose browning</a>  <font color="#6f6f6f">Nature</font>

ROS–Jak2/Stat3 signaling drives HBV-induced liver inflammation
EurekAlert! Science News Releasesgeneral

ROS–Jak2/Stat3 signaling drives HBV-induced liver inflammation

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE95eTc1VHRZYUxpazczRTlVUkJldFF5Ym9ETEV3MmhVT1RYN295Y1BVUFVKNDhUQ3FoV2NBRnMyX21MOTh6cncxU3lJNW9CLVo1NnZabDRJSmxPM09Z?oc=5" target="_blank">ROS–Jak2/Stat3 signaling drives HBV-induced liver inflammation</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

Leaked mitochondrial DNA triggers cGAS-STING signaling, accelerating ovarian aging in oocytes
Bioengineer.orggeneral

Leaked mitochondrial DNA triggers cGAS-STING signaling, accelerating ovarian aging in oocytes

<a href="https://news.google.com/rss/articles/CBMiuAFBVV95cUxQTHZRc2NnQ3Z4NHdodk95YXFRWkpsSEhaN3FlVllEaXJSYzB2dW43eVk1bHlyVHp6SHRvN2xkS1E4RnE5SXkzLWF2bUVGWk5wNWphZE9VZ3hoNlRpQUVDRlg5ZXM3ODRmZW43VHhBMnU0a21DV3hqMXgtYXJhNjlXdG82N0cyYTRBSEhqLWRZZ0RuV0hyQmtsZGJ0QzhSSW1UNjBrTDVoMWh5VmRRVE42X3RQRlVib2sw?oc=5" target="_blank">Leaked mitochondrial DNA triggers cGAS-STING signaling, accelerating ovarian aging in oocytes</a>  <font color="#6f6f6f">Bioengineer.org</font>

Mitochondrial metabolism and epigenetic crosstalk drive SASP
Naturegeneral

Mitochondrial metabolism and epigenetic crosstalk drive SASP

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE44T09zNzFDNlptNUJqaHk2VWNwOEpzanpwMENqOFBNbjBfYXJ2aEwtQm1SS2NqWWlyZ1E3bXVEckVKallHZkpRWjhyR2loTER5UjNTM2pEMjZEQVcxVHVz?oc=5" target="_blank">Mitochondrial metabolism and epigenetic crosstalk drive SASP</a>  <font color="#6f6f6f">Nature</font>

Mitophagy and Ubiquitination Coordinate Context-Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion
Wiley & Sonsgeneral

Mitophagy and Ubiquitination Coordinate Context-Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTFBpS2taV1ZyR0w1cGhLNDhfU1BCLUFZeF8zTlJLUjNXdUYwbUJUdE4wR0NWN1RTTm5vRGRnTjltNU9WSzQ0Q0d6N2J6LXNGMXQtZ0JkSHd0a05JUllxTVlPUldGWWpCNGJPMEo1bHN6TmEzODlkU0E?oc=5" target="_blank">Mitophagy and Ubiquitination Coordinate Context-Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion</a>  <font color="#6f6f6f">Wiley & Sons</font>

Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses
American Heart Association Journalsgeneral

Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses

<a href="https://news.google.com/rss/articles/CBMibkFVX3lxTE5HNjJ6VkpQVE84MEUzTEtfU0xzVHF2MmkxeHpDeW1CbjJrbVB4aUQ4Mk9FbklWT2QtQjdsWkhhZHpmTDl0X2hiLTZycFB1bGJ2VTY5M1I4TlVKR1o5aWliMTAyT0M0eTNzcHEwcklR?oc=5" target="_blank">Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses</a>  <font color="#6f6f6f">American Heart Association Journals</font>

TRPC6 loss triggers mitochondrial dysfunction that drives white adipose tissue vulnerability to obesity and insulin resistance
Natureworld

TRPC6 loss triggers mitochondrial dysfunction that drives white adipose tissue vulnerability to obesity and insulin resistance

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE82Z1RfMnI4c1VyOGdnbnh2c0pZS2gtREp6OHdkdFdKTTlRMnFCdDhDV0w5NGJHQkx1UmVKMzRlX3dnMi1yUEJINTAxbnFyZFRHX0NuejRmWDZha3l6cC1v?oc=5" target="_blank">TRPC6 loss triggers mitochondrial dysfunction that drives white adipose tissue vulnerability to obesity and insulin resistance</a>  <font color="#6f6f6f">Nature</font>

Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia
Naturetech

Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5CRi1kc3I5OEJKMmJoZ1E1eUg2Q044eTI4dTh6bzI3RkRLOTRxV2dfTHY5WG96blMtZFRWa1NwUXUyQVFzc2ZoSFlMcTVQZkhDRGxCbFh6M2FTMDFqb2VF?oc=5" target="_blank">Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia</a>  <font color="#6f6f6f">Nature</font>

Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation
Natureworld

Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5peGhsVF9uNmxCRC00ZjQ3c2pNRDdUQnpmZklMV1FnT0VOLXBISVE5RkI5aGg0cHlYOWJPOC1jMEVEckx5VElFOWRiWTh3MlFIUW41VlNHVkk0OGNjRVF3?oc=5" target="_blank">Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation</a>  <font color="#6f6f6f">Nature</font>

Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure
Naturetech

Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5iSm40WE5rbXU2MEVZclpCYU1FQ1pWdm9hcmxhQXVjcWxVQ2s5REtOVXh4RDVadjVjeHVKVzVRN0ctRHJiblpaTUlRbmhVQUxYTWN2S1BkNVNscjVfUk5R?oc=5" target="_blank">Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure</a>  <font color="#6f6f6f">Nature</font>

CPT1A drives cisplatin resistance via acetylation‑dependent activation of DRP1 and mitochondrial fission in small cell lung cancer
Natureworld

CPT1A drives cisplatin resistance via acetylation‑dependent activation of DRP1 and mitochondrial fission in small cell lung cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1Ld2xnSERIRklrZ3EyeWNhZjk3ZkZqdk9uTXM4UDBxVjJvVDZrQ1pxWEJ0S0Q5SV9PZlJYV0F3Nnk3UXU5bUNOX3ZOREFmZXlHc3BuLXlRUWJkMzJRbXpn?oc=5" target="_blank">CPT1A drives cisplatin resistance via acetylation‑dependent activation of DRP1 and mitochondrial fission in small cell lung cancer</a>  <font color="#6f6f6f">Nature</font>

Mitochondrial RNA cytosolic leakage drives the SASP
Naturegeneral

Mitochondrial RNA cytosolic leakage drives the SASP

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9fZ3UyU1dVQzBlX0xMQnZzb0dPNEtaQXJubGtmZC1uS2s3RlNZM1lZSkxuMElvQ1h2MXpULU9PZUxSaE0tcGlrZ25kb2tHTjlBeEQ5bVp4QlFRZ0tFRm5F?oc=5" target="_blank">Mitochondrial RNA cytosolic leakage drives the SASP</a>  <font color="#6f6f6f">Nature</font>

Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations
Naturegeneral

Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE02MlVyVTBZWDRKelI4dGlVaW1vemdHakxFcEdOakQtdEZnRjBQUTJtNnhsbWJUakV5OFZHSTlHNkl5ODNBckhUMjRpUUdqazhkeGhNd0dTTV9RamlwN2xv?oc=5" target="_blank">Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations</a>  <font color="#6f6f6f">Nature</font>

Mitochondrial dysfunction in cellular senescence: a bridge to neurodegenerative disease | npj Aging
Natureworld

Mitochondrial dysfunction in cellular senescence: a bridge to neurodegenerative disease | npj Aging

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPeW9VQWMxMjFjN3dZN1ktbDlidUNIYVZ0V2tkZnFrMTVITWlZeXBxMDFvQUhxZG5sZWtVSmw3TGZsWUVOQlNPclE1ZmdfdTIzYll5VXRSVzExMmE3aFVv?oc=5" target="_blank">Mitochondrial dysfunction in cellular senescence: a bridge to neurodegenerative disease | npj Aging</a>  <font color="#6f6f6f">Nature</font>

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L
Naturegeneral

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE5nNV9SM3dmSnhObjdPTzJfcGoxVEhPdUdwRnBqcUdXVXF1Wi0wdVpGS2dET1lQSExhYi0takRPRDFHSDhRblBrZnB4amFEUEU5ZmkyNmpkb0RWUUpNMEE?oc=5" target="_blank">Lipid signalling drives proteolytic rewiring of mitochondria by YME1L</a>  <font color="#6f6f6f">Nature</font>

Ribonucleotide incorporation into mitochondrial DNA drives inflammation
Naturegeneral

Ribonucleotide incorporation into mitochondrial DNA drives inflammation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9wYnpyT1pTUEtUNjQ4NG9MZzdGR09SZ2dzVUVwZjd6MmY0dlhXdWRkUUJKY055UEgzQkZDWDZKU050cWZyOXVDUkl3T1hjVmF5a0lIYnBBbUUydlFEcTRn?oc=5" target="_blank">Ribonucleotide incorporation into mitochondrial DNA drives inflammation</a>  <font color="#6f6f6f">Nature</font>

Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution
Naturegeneral

Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5BQ04wTmdrSXNUbno2YmY4dVd0M1F4UXpSOFZZTjk0SW5uYll6YmphMlZoRHZGQ19GRlpxYkJ5RWtVX0RaOEgwbU4zT2RVek1WSzJtRzU5VFpKcGI3ZnM0?oc=5" target="_blank">Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution</a>  <font color="#6f6f6f">Nature</font>

Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction
Natureworld

Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBsNU1ISFl3dFA1NTNNZ0FmbkN5Mkc4R1hGNWkwQ1ZLT3MxTFp4WldnNEdLNWxxX0p0YzUzRjZPNHFzWHFsRHhpUHp0cVBmQzl3SzdsRFk2a0dsN3hNR2Zn?oc=5" target="_blank">Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction</a>  <font color="#6f6f6f">Nature</font>

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
Science | AAASworld

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

<a href="https://news.google.com/rss/articles/CBMiZEFVX3lxTE9aU3gxd3Z5UXNfWFVyN19VdGsxbkZIa21DSnNaV2Y0MHlPSllBNEFhcmlUV19pWW1JMnY5RUlKQ2MteE5RLTc5TjF2YzZjbEF1SlpWTFRYak8xTkV0Z3U3cjc4QWw?oc=5" target="_blank">Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity</a>  <font color="#6f6f6f">Science | AAAS</font>

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease
Naturegeneral

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5xdFpYbm9mVTJYMnhlR21PdEw1ckZJRVF4WWM2cW9YcTY3bjBqb2ZCWGZDT1BfN2hHSzJKMEwwNU84VThEcUU1VmpHd1NVTVNMRFgxSHQ2Z0tOLWQ4aG1Z?oc=5" target="_blank">Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease</a>  <font color="#6f6f6f">Nature</font>

Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overload
Naturegeneral

Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overload

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1mbkk2bkxDRTdwZXJpYTFIVGxNcGY2M0RXVi1Rdjhsc29ESmNUZHh2cWQ3cktPWElfeVgzdXFoRHZkVjVFeEJ6RkdCMVRvRU5hWTl4Vk51NGNodHRzZzhz?oc=5" target="_blank">Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overload</a>  <font color="#6f6f6f">Nature</font>

α -Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron–microglia communication
Natureworld

α -Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron–microglia communication

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9TUVZLT0FBSmVaYjgtc1pNVHlES0VBYmw2dHVCSERJaFd2UU05ajJnMjhkY09tcGZKQktEeGdoQ1VCQVUwaHV4c1U4bEk1TndSeWgzbDJCYTd0Zm5wVWtn?oc=5" target="_blank">α -Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron–microglia communication</a>  <font color="#6f6f6f">Nature</font>

The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence
Natureworld

The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE84OElxR01CcG5Pd2xUX2gyYkRSSFFWXzQ2Y3N1SVFRRE9kdmQwNkRYZmw2MVJMbGhPOWZWTEhlcG9heGQyYnNvQzJEZEVWQXcxMWNNWVlUaDJ6akN5S1NZ?oc=5" target="_blank">The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence</a>  <font color="#6f6f6f">Nature</font>

Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4
Naturegeneral

Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBlQmNkQ0g3MEFncU82azBzb0dOY3lFTGpGRWtkOGdyNUlQWXpnSmR6amRyZVhUa3o2RnZTZmNCTGl6cll3TS1BT2dnTTRyZnlQNkVnRTlsZzdGNkR5ZUkw?oc=5" target="_blank">Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4</a>  <font color="#6f6f6f">Nature</font>

Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGFβ1-mediated tumor progression
Naturegeneral

Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGFβ1-mediated tumor progression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5vU2pGT0JSUkZzVmpVTGNnbDNjZkpjSTFmMm9ZOFpkWlRtT0M4aHJmN1VxWjJyQk1hZjNuM01odGJVU0x0NXFxemg2TG9scVFjczA4enNFQkdtR3pWQkxJ?oc=5" target="_blank">Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGFβ1-mediated tumor progression</a>  <font color="#6f6f6f">Nature</font>

A druggable copper-signalling pathway that drives inflammation
Naturegeneral

A druggable copper-signalling pathway that drives inflammation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ycnlIckhrNl9GMDdZSzBTemFScm9IcDNLY1BCcUZ6OUgwSmx1SlNwcnEzWlhKZUc5dmhidEtGbmFWbXNwaEc5M21Rdk54ZkRlWlhjd0dxbjl6RnNuRFVJ?oc=5" target="_blank">A druggable copper-signalling pathway that drives inflammation</a>  <font color="#6f6f6f">Nature</font>

Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence
Naturegeneral

Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9IOUVTZ0l1akhVWU0zVFhnVU8yY3hjVlFlb1BSV1J3NWo3QWdKQ3dsbjhtamNBMHdMZzBSTmRfZkZRZTZxUE42azlYXzRNejV2bkl2bUdsRmdrN3ZvS3lj?oc=5" target="_blank">Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence</a>  <font color="#6f6f6f">Nature</font>

"Signaling Drives Mitochon" — Live Google News Trends & Headlines