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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Receptor allostery promot" (30 stories)

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Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development
Lead StoryNaturegeneral
Jul 24

Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5pNGxienpnLXpIX3hiMndEZVA0NFd0NzVYTDZNRDFHclFmYlZfWjNVWnB5XzV2Sk5OQk1rQWU5ODl5WElQVTRHbUxPbmpwbTBxOWpSbTZFZWJmampNV3dn?oc=5" target="_blank">Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Receptor allostery promot"

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29 stories displayed
Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2
Science | AAASworld

Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTE91MTZ2c2pDWnB0cDFZTFlFWHJNTkdiQnhqN2hPWG1xRjlaZVB3WnFGLXA4ZFdib1V6OFV0MHR2ZjdsdGQyQnhaWi1wd0R5bUxkZUtSb0kyT0k0SlJ4ZGdHdkIybw?oc=5" target="_blank">Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2</a>  <font color="#6f6f6f">Science | AAAS</font>

Molecular mechanism of allosteric modulation of opioid receptors
Naturegeneral

Molecular mechanism of allosteric modulation of opioid receptors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1Pd0QxUThteVpOS29Vem5qc1B6bFZoSV9hYllIQUFnTHB1RGZOd0J4dGFabGpSYzJBaXpoeWxYQU5FQ0g2ZmpBZ1haQ2stSDNvblZ1STRfQjB6MV94RVBz?oc=5" target="_blank">Molecular mechanism of allosteric modulation of opioid receptors</a>  <font color="#6f6f6f">Nature</font>

Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor
Science Tokyoworld

Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE9xMW41T3ZwdnVVREEtYWF4YlRCdkVtVkRxaVY0VGFGSE0xUFNwbXM3amJualNxUFlPV2xPQXZaOXBVNmd5M2FpQUlJdEd1cl9aM1A0Q0d3?oc=5" target="_blank">Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor</a>  <font color="#6f6f6f">Science Tokyo</font>

Allosteric modulation of G protein-coupled receptor signaling
Frontiersgeneral

Allosteric modulation of G protein-coupled receptor signaling

<a href="https://news.google.com/rss/articles/CBMilgFBVV95cUxQR1NGUHc1ajJVZ0NaRnB3MEF3WDl1QjQtMjJCTTJhUGs4V3BlLUs0SU9VME1HZ2RFdzJRZkpDYkRFVkhnS0NQTVRveVNMb1FZcDk3eFNEcDRoN01RSDFxTy1sSGxpVGFIY1RkRF9nWGtRS0l2MmMtTXlLWTNaM1JmYTViWDZDa0RIWmFBbVdtMlNIdU5aOEE?oc=5" target="_blank">Allosteric modulation of G protein-coupled receptor signaling</a>  <font color="#6f6f6f">Frontiers</font>

Positive allosteric modulation of a GPCR ternary complex
Science | AAASgeneral

Positive allosteric modulation of a GPCR ternary complex

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBwME5za0d5Y3FhOTRJWkZrY0JMemdTVzk0Z2ZFV1ZqUzVOclFpelRwd29hOU9ENVk3NzJpZjJWamlZckJEV3lNaGgwNVI0TUpqLWhkTTVKbUZSaW5PTEFN?oc=5" target="_blank">Positive allosteric modulation of a GPCR ternary complex</a>  <font color="#6f6f6f">Science | AAAS</font>

Structural basis for positive allosteric regulation of CB2 receptor
Naturegeneral

Structural basis for positive allosteric regulation of CB2 receptor

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBsS3RUTWJlTG50VDJ3cFNNUVZBY19zTjdUcmVoSTRNazZNcXZnTXBBM2VueUN1dGxXOHVOSHhoOGgwaHFWZHpyWWw5bHBNVGI3dzlpeC1pZF9Vekwyd1Zv?oc=5" target="_blank">Structural basis for positive allosteric regulation of CB2 receptor</a>  <font color="#6f6f6f">Nature</font>

Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks
Naturegeneral

Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB1NnR6Q1F3eUxLdEpFZzZ3N3ZMbV9MVU5aNFAxTjE4aF9vc19xTUY4b2FfeEROZXFGc0doVEVtanItNjJhNFE1d0N2dmwxSnFEN0dMazZEbTgxaVloeXVn?oc=5" target="_blank">Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks</a>  <font color="#6f6f6f">Nature</font>

Functional and structural basis of a negative allostery within GABA
Natureworld

Functional and structural basis of a negative allostery within GABA

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1vbWxTZ0l1aGxPNGpzLWhHbmtEZmtFVWxKZ1ZIOWNHR2ItQU0wY1hDMG40azR1Ri10M2IwZVo5eW00VWY5S2s2RHIzd2ZIcmNoMlBjOEdNM19obTRkczNj?oc=5" target="_blank">Functional and structural basis of a negative allostery within GABA</a>  <font color="#6f6f6f">Nature</font>

Allosteric modulation and biased signalling at free fatty acid receptor 2
Naturegeneral

Allosteric modulation and biased signalling at free fatty acid receptor 2

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9EdWZpLWRGcDA4M3pVc0VmU0RqRjhxNkEwQ2VNNWxhY1hucEZFbU9HRGQtQ0ZUeS16WTlFMGlYUTFCUk9jOXRpejd1bW5IUDN6QWJQWXBLbU9tSjVoMTB3?oc=5" target="_blank">Allosteric modulation and biased signalling at free fatty acid receptor 2</a>  <font color="#6f6f6f">Nature</font>

Designing allosteric modulators to change GPCR G protein subtype selectivity
Naturegeneral

Designing allosteric modulators to change GPCR G protein subtype selectivity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5RSUZGcVVuMkllV0RkcVJDTkluUXhaam9aS3FUbjlPcEZrR01UTWg5QzloeFJfVE02R3hjb0lFMkdUdGZqZ0U2aFdIRjVLcE54OTk2ZXMyWnNobFJ4VjdR?oc=5" target="_blank">Designing allosteric modulators to change GPCR G protein subtype selectivity</a>  <font color="#6f6f6f">Nature</font>

Structural and mechanistic insights into gating and allosteric modulation of GluN1–GluN3A NMDA receptors
Natureworld

Structural and mechanistic insights into gating and allosteric modulation of GluN1–GluN3A NMDA receptors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1iZ3JMVjh0bkxEd1hGdXBxNHJLbk9CNzBLbnNERGtpZFc0MGlMM1ZYYldhZEE1N0VpQ3B5UkVuSVdpcWR2cmdwNDF6eEpJTDU2T2ZJc3IwZWtBV2lGWHJr?oc=5" target="_blank">Structural and mechanistic insights into gating and allosteric modulation of GluN1–GluN3A NMDA receptors</a>  <font color="#6f6f6f">Nature</font>

Computational design of G Protein-Coupled Receptor allosteric signal transductions
Naturegeneral

Computational design of G Protein-Coupled Receptor allosteric signal transductions

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE9UNVhqME9UaHotbjJRUkh0MHRVSi1EUWI3eE8yaHgwZ1JkTEJRYzJqUkY3VW1sSkdiM1ZuVFNEcWVlNzd4ZTU2TG95OHNfbmpRRk0yZmVYei1LMDY1aFE?oc=5" target="_blank">Computational design of G Protein-Coupled Receptor allosteric signal transductions</a>  <font color="#6f6f6f">Nature</font>

Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor
Naturegeneral

Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1KNEItbHdPLWlOZUVINWNwYlV4a2kyWWVEMGY0TG1MV3dPQ0lrcmcwc1JUNjh0MkEzdWQ3UWxRZnd4M3I2Z0RTUlVuS1dXbmR4aHRqY19fQUJCYlJIYnlB?oc=5" target="_blank">Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor</a>  <font color="#6f6f6f">Nature</font>

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication | Scientific Reports
Naturegeneral

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication | Scientific Reports

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9BUjZUTU14UDhOQS0wbGxieUo5NkJHa2xvTlFVY3JFa1RjdTdKbFZ2dTlBNV81ZXVKYXplRUdkQUpGblJEeWpRWEtCRTVSdXk1c0h2Z2F2NzEzMHVSS2hN?oc=5" target="_blank">Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication | Scientific Reports</a>  <font color="#6f6f6f">Nature</font>

Illumination of a progressive allosteric mechanism mediating the glycine receptor activation
Naturegeneral

Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA0MW1Od3hicGpIbzM2YnVpTWRrNHUwNWhpendHTjR3LUVVZ0txemh0YV8zUjFjNVFiS09DbGR4Y3k2a0FTQ2tSbERHNjFLQm5RWEtzUzhyZUJXblVIZjRn?oc=5" target="_blank">Illumination of a progressive allosteric mechanism mediating the glycine receptor activation</a>  <font color="#6f6f6f">Nature</font>

Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator
Naturegeneral

Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5qbDB6cUpNR25TNGJBd01mMFlXMzJBREpBRTdzOWhjZm1GczZVQmkwZW5sajBqeWdiM05HYnB1TklseXhhaXdWZVVFa05qcG5lcm14VjM2V0g4SjlkLURJ?oc=5" target="_blank">Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator</a>  <font color="#6f6f6f">Nature</font>

muscarinic receptors enhance acetylcholine efficacy and decrease locomotor activity and turning behaviors in zebrafish
Naturegeneral

muscarinic receptors enhance acetylcholine efficacy and decrease locomotor activity and turning behaviors in zebrafish

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5rU0dqQU8tdUZESFFEWkdrc1JZVHFROHVOSU5hYVdQZ2tfbjdTQzNOZjQ5M2FyU3pBQTZ4NFptWXdwRGdfaFJraDJGRW00YjdUcTJ6aHpIaWFvNzBjb0Qw?oc=5" target="_blank">muscarinic receptors enhance acetylcholine efficacy and decrease locomotor activity and turning behaviors in zebrafish</a>  <font color="#6f6f6f">Nature</font>

Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors
Naturegeneral

Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE10UGVwd3ExSV80Y0dXRlJoVGVXMGtmTUF0TmJHd0FGQks5RzdrRXlYM0NLVE4xRUh4NTl6R0ZyS19iMHdfbUJBQjFjWVVUV0pkZm5F?oc=5" target="_blank">Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors</a>  <font color="#6f6f6f">Nature</font>

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design
Natureworld

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5LVDFqSTlDZm16cF83SkFLa2xmQ0tpQ05OaV9nRm1VdWVZdUxRTEJ1NWprV21zQW1ZTnI3cGdsbGs2X3BGQ2hZT3Q1Y211SnpNY3BoNXNKX3UwVHRXZm1n?oc=5" target="_blank">Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design</a>  <font color="#6f6f6f">Nature</font>

Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor
EurekAlert! Science News Releasesworld

Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE11VjBwcm1DS0xHbTQwaXdTUlppbHJBenpnc21XRGVGMXhxZ2pUN1V2N25UdGNQU2ZlWkdUQlhsbEdBMmlCZXo4Z29YU0pjdFFwOThTYUF0aGJhb2Ny?oc=5" target="_blank">Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

adenosine G protein-coupled receptor by physiological cations
Naturegeneral

adenosine G protein-coupled receptor by physiological cations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5VU3ZBS0tvXy1Hd2lLckFVODFBZjUzZ0FWaTdRUW9nVmhBa283Q0ptSWc3bHotcGN5cWF5OWJzdEtyME9DLWpFUkEwV1ZNaUpDaXN0R2tHNWwwUllpanE4?oc=5" target="_blank">adenosine G protein-coupled receptor by physiological cations</a>  <font color="#6f6f6f">Nature</font>

Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor
Naturegeneral

Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBBZ0ZmdE1LbWZMWjFDUEpwTjAyaTM1RW9fMXVJa252bHlXOEV5MjJfNk9DOGRCY2VPZ0lfVmhnbzV2Yk9XWXVlQXFVNFNqREtTanRGM1VqaHhxaDNXVGJ3?oc=5" target="_blank">Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor</a>  <font color="#6f6f6f">Nature</font>

Dynamic Allostery in T Cell Receptor Specificity: A Role for Peptides and MHC Polymorphisms in Allosterically Tuning Immune Recognition
Wiley Online Libraryworld

Dynamic Allostery in T Cell Receptor Specificity: A Role for Peptides and MHC Polymorphisms in Allosterically Tuning Immune Recognition

<a href="https://news.google.com/rss/articles/CBMia0FVX3lxTFBfNVJNaU1WbkM5RWE1RzlpN2lXWlBjNkdtcGVGOTBGakpMaFIzV2dRbmEwZ0hkSEJWNDBURlJpWVFWWGdBZnNNTXpqTHMtem84ZF9oaUlmY1dsVC1yTk1FdXkyeHdKekV3M3hn?oc=5" target="_blank">Dynamic Allostery in T Cell Receptor Specificity: A Role for Peptides and MHC Polymorphisms in Allosterically Tuning Immune Recognition</a>  <font color="#6f6f6f">Wiley Online Library</font>

Allosteric competition and inhibition in AMPA receptors
Naturegeneral

Allosteric competition and inhibition in AMPA receptors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0xeXBmTEFHczJlX01mekNvd1JKbWNndWxVSHpZVTRVNFFKRTgybHBSanRUaDIyeDJVanBaSnBnbTRVOUJ2MnY0TnBiTkhPZkkwYml1RkwwWnZZbURySkVR?oc=5" target="_blank">Allosteric competition and inhibition in AMPA receptors</a>  <font color="#6f6f6f">Nature</font>

G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery
Naturegeneral

G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAtZlpfXy1KMzVvT296XzRoSUpsVEROZ0ZzYTFYY19Xb01rN3RyVGpNTWtoNl91YTZFU0xHOGJtLTRzVEdPRFdic05Nb3pvOVBKNHduTzRFOGhuOVZFYW9J?oc=5" target="_blank">G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery</a>  <font color="#6f6f6f">Nature</font>

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role
Naturetech

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTFBwS0JZSHNqSGlkeEJIRmh5RncwNlp3OHpQaWNndzF0M2piU3FxN0tSSWdJTzlwM3JDaDNkSWY4eUFTSjV5NTNtV1N2b0tTT191bFBNX1VR?oc=5" target="_blank">An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role</a>  <font color="#6f6f6f">Nature</font>

SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor
PNASgeneral

SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFA4aXhJUnl0QUh4Z0V2dVV2TGVtNzZFb1kwd2QwSDBiR0l6c1pIQ0pRMlJ0OFR6N0lRSDNqbGI4TWxXdFc2UDlMWXprY3A3NVNqQW9JM2I4cWZSaXRS?oc=5" target="_blank">SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor</a>  <font color="#6f6f6f">PNAS</font>

Cryo-EM reveals an extrahelical allosteric binding site at the M
Naturegeneral

Cryo-EM reveals an extrahelical allosteric binding site at the M

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9uZkF0TmFPNUhtcU1PTFd6aFFhX08wdmhmUHFRay1IUWhodE1JNmoyVm9VTWtRMWNFdmZQMW1XbXdEUlhfLTdsX1NxSkNFNFNJMzh4QkdkcVNNdDhHay00?oc=5" target="_blank">Cryo-EM reveals an extrahelical allosteric binding site at the M</a>  <font color="#6f6f6f">Nature</font>

Allosteric Modulators of Sigma-1 Receptor: A Review
Frontiersgeneral

Allosteric Modulators of Sigma-1 Receptor: A Review

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxNeS11c1ctSm1raWtfRWtwVmFQTmN3VnRFYzhZTDdKMjB4OWM4TWhPMkk2bW0ySm9DQUh3dWlfbXBpLW5qdTgwcVR0YzZOc0JUVVEwOXljZnQ3ZUhFQjlubnVRbzNvWk4ySVlnSzNNa1JOZW1FVnljQndzTW1zSEJ2Mi04c2Rjbzg0eHkyd1d3RExFQQ?oc=5" target="_blank">Allosteric Modulators of Sigma-1 Receptor: A Review</a>  <font color="#6f6f6f">Frontiers</font>

"Receptor allostery promot" — Live Google News Trends & Headlines