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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Rational optimization of" (30 stories)

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Rational optimization of a transcription factor activation domain inhibitor
Lead StoryNaturetech
Dec 4, 2023

Rational optimization of a transcription factor activation domain inhibitor

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE03OEN5amttOHZfS2IyejNob3I4ZmlZTTVxRmJJYjFnLVU2TW83T3FaYVNKOWh3bHd0NEs3eGxQNVI0bm1mN1ZheF9aUVJESEVod3p0MEdOUk11VEkxUWNB?oc=5" target="_blank">Rational optimization of a transcription factor activation domain inhibitor</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Rational optimization of"

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29 stories displayed
Rational and Multidimensional Optimization of Nanozyme Catalytic Performance - Xu - 2026 - Small
Wiley Online Librarygeneral

Rational and Multidimensional Optimization of Nanozyme Catalytic Performance - Xu - 2026 - Small

<a href="https://news.google.com/rss/articles/CBMia0FVX3lxTE1raGhwYkFfZkxCeFJhcGQ0dF9tTWd1NnV0THY0MFBmaS0wNy1Pa0hpOWU3Z3MzTlNaRjRNc29mUnlSbVNGWGRPczVZbEFMYklVRjUzdW9NNGdjM2hfbTlrd1Q5WXdnMUVhb2hj?oc=5" target="_blank">Rational and Multidimensional Optimization of Nanozyme Catalytic Performance - Xu - 2026 - Small</a>  <font color="#6f6f6f">Wiley Online Library</font>

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Advances in adsorption processes driven by machine learning
EurekAlert!general

Advances in adsorption processes driven by machine learning

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE8wYnl1LUZWY0ZLOUxiWEwyV050R0lnZW9qUEptM0ZzUUhuMWlOaWYtelVkSGx4OENpcG5PSjhwUXNzcEpjczQwQTlCRUd1YV9Ta3A3MTR1em5hTHBo?oc=5" target="_blank">Advances in adsorption processes driven by machine learning</a>  <font color="#6f6f6f">EurekAlert!</font>

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Multiscale insights enable rational design of solvent-free dry electrode processing for advanced battery electrode fabrication | Communications Materials
Natureworld

Multiscale insights enable rational design of solvent-free dry electrode processing for advanced battery electrode fabrication | Communications Materials

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5uRGlTY0RNMFJjZWR4NG5DVmhXQjkybjcwTmZoei1JeVMzc0dsNVVqRVZEbU9UQnNMemFwRUJCeWxqRnI0Z2cxNmFRTmM1UV9la0ZSZ1A4ZkZtX1JzbDk0?oc=5" target="_blank">Multiscale insights enable rational design of solvent-free dry electrode processing for advanced battery electrode fabrication | Communications Materials</a>  <font color="#6f6f6f">Nature</font>

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Rational design 2.0: transitioning from static structural biology to computational prioritization and iterative vaccine optimization for RSV
Frontiersgeneral

Rational design 2.0: transitioning from static structural biology to computational prioritization and iterative vaccine optimization for RSV

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPeER6d0FBb0Y1Yy1qaEs0b3lyTGd2aE9ON2NUREVZMzJVOTVwYlUtcllSZW5SU2xzdWFjMUxYZWU2YktlTjhYQlFlZXdkSmNWSUNLa0RaQ0xiaHcyYzNVTEdHS1lCUGJYajgtTkp3WHFOMkxUVEV2TDBVdzNOQWd6N2h0bzktM001aG9RSjdJdERfQQ?oc=5" target="_blank">Rational design 2.0: transitioning from static structural biology to computational prioritization and iterative vaccine optimization for RSV</a>  <font color="#6f6f6f">Frontiers</font>

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Contested Logistics | AI, Optimization, and Rational Thought (A Mathematician’s Lament)
Army.miltech

Contested Logistics | AI, Optimization, and Rational Thought (A Mathematician’s Lament)

<a href="https://news.google.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?oc=5" target="_blank">Contested Logistics | AI, Optimization, and Rational Thought (A Mathematician’s Lament)</a>  <font color="#6f6f6f">Army.mil</font>

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Rational assembly of 3D network materials and electronics through tensile buckling
Science | AAASgeneral

Rational assembly of 3D network materials and electronics through tensile buckling

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE10aWtFVG5SU3o2SEhUdlJvaHpqamRNWDgwbnlJdThqd0Q0UThQOC16MHpHNDIxWEh0RWhOUXNFaFdkS1VYYzEtQ3liMjd1QVltdWRMbV9lXzlzUjFEWGdB?oc=5" target="_blank">Rational assembly of 3D network materials and electronics through tensile buckling</a>  <font color="#6f6f6f">Science | AAAS</font>

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Machine learning-assisted kinetic matching model for rational electrode design in aqueous zinc-ion batteries
Naturegeneral

Machine learning-assisted kinetic matching model for rational electrode design in aqueous zinc-ion batteries

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9SUWhBY2p0ODhaQUFjbnpQVnFTZFhBVjZZOU9QTDVnWnlCWHFHekc1Um1vQUJPRUE5a1FubEN4SVBKYWZrZ09JZWdPNTZCTEU3LUNYdmVBaGhwVHFEbms4?oc=5" target="_blank">Machine learning-assisted kinetic matching model for rational electrode design in aqueous zinc-ion batteries</a>  <font color="#6f6f6f">Nature</font>

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Rational design of mRNA nanovaccine for cancer immunotherapy
EurekAlert! Science News Releasesworld

Rational design of mRNA nanovaccine for cancer immunotherapy

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE5GNUZVUEpnRFhLWXhxdlNoR1E3c09mbExJbG1QVjlRY0Y4RHZPTnpuZkcxYjN4UUpoTUFtNDFPUHJyQ0ZqeTlrNi1QNHljajdYdld6RWNyLVpqY0dk?oc=5" target="_blank">Rational design of mRNA nanovaccine for cancer immunotherapy</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

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Rational design of thrombin-derived VFR12 analogs with enhanced antimicrobial, antibiofilm, and anti-inflammatory properties
Naturegeneral

Rational design of thrombin-derived VFR12 analogs with enhanced antimicrobial, antibiofilm, and anti-inflammatory properties

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5mY2dGZmZRYzA2NnJwMkdPSXhxVXBmNFF6Q3g3ZklZZW1ROHliT1VlY1Q4QURaa3MyQllQR21sVTdrSllnZzhUNFN6T2Zpc1VUVkFZV1JZT3lyNS1VQkdR?oc=5" target="_blank">Rational design of thrombin-derived VFR12 analogs with enhanced antimicrobial, antibiofilm, and anti-inflammatory properties</a>  <font color="#6f6f6f">Nature</font>

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Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces
Naturegeneral

Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE02VGY0bnVUN1k4NDFLdlBwb2I2UWsxZEUtYVVJUFRMcHA0VE1ObUNPaVY1RHlscmk0Z3dLblNUXzFjYlVXa2ZLWmJTV2ZXNDNaMzdn?oc=5" target="_blank">Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces</a>  <font color="#6f6f6f">Nature</font>

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Data-driven surrogates of rational design enable antimicrobial peptide optimization
Naturegeneral

Data-driven surrogates of rational design enable antimicrobial peptide optimization

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9GaU0tX1NQc3J5UzdialFMT1hoOVNybHJ3OG5nRG00QnRlVndKc2hfcHZxLUZMbGcxenlfZFNDSl9OcUhqWHJ6d0RiNGVjbUJyZUJVbnRZTEJQSWhmSVln?oc=5" target="_blank">Data-driven surrogates of rational design enable antimicrobial peptide optimization</a>  <font color="#6f6f6f">Nature</font>

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Rational strategies for improving the efficiency of design and discovery of nanomedicines
Naturegeneral

Rational strategies for improving the efficiency of design and discovery of nanomedicines

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE12a0pCWGNNUUh2TXFWeFBGdTVVR25aMDE4SEgtbEVlWHAyeFBLMzZHeXoyWS1RRGE3d2txdVQyQm5GLWdqUlk5dTJob0lmZGhEZVdDbjNSNWtEVUFzdWdF?oc=5" target="_blank">Rational strategies for improving the efficiency of design and discovery of nanomedicines</a>  <font color="#6f6f6f">Nature</font>

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Rational dsRNA design, scalable production and nanodelivery to enhance spray-induced gene silencing
Naturegeneral

Rational dsRNA design, scalable production and nanodelivery to enhance spray-induced gene silencing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE45ZnRyNUhMSHc0NmIzd0syeHRfQXZFTkJ6Nld1TkpVajE4LU5sUTNiS1ZEUTZudlBfbFN3Z2txYlRwVkFLOUo0NnlfVXpaZUVYNFZUNW5uM3hlcWJvaGFN?oc=5" target="_blank">Rational dsRNA design, scalable production and nanodelivery to enhance spray-induced gene silencing</a>  <font color="#6f6f6f">Nature</font>

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Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity
Naturetech

Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5UUWkyZTktc0VJSzltRWQtREFEYlEyR0xUNjN2aFl1RnFSWHd1MVZNamFNZ2xMeTI2WThzeGpZLURHc3FXcDNuYnRsblBBX09teHR4UnM2QWVPa3JmU0JJ?oc=5" target="_blank">Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity</a>  <font color="#6f6f6f">Nature</font>

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Deep learning–guided engineering of SpuFz1 and rational miniaturization of ωRNA enables efficient genome editing
Naturegeneral

Deep learning–guided engineering of SpuFz1 and rational miniaturization of ωRNA enables efficient genome editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0wY1llLWFJNVhNVW1rb3ZJS04wQV84OFFyaHU2NTRfN3hxTjhqdDFUUUMxalNtWmhIRGJTSndyakNJTkZhRU5HbE83bDZfZkVVdkp4T1pKdHlGS0x0LVlN?oc=5" target="_blank">Deep learning–guided engineering of SpuFz1 and rational miniaturization of ωRNA enables efficient genome editing</a>  <font color="#6f6f6f">Nature</font>

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Towards rational design and optimization of near-field enhancement and spectral tunability of hybrid core-shell plasmonic nanoprobes
Natureworld

Towards rational design and optimization of near-field enhancement and spectral tunability of hybrid core-shell plasmonic nanoprobes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBjSHhpUGtaamNzd1Q1aWZmNnZ3aXpOdDYweVV3NDB4MU04Y0RVbUtGMzc2cDhzVy1SU3hzQU5RTkJSMW1qeFFEak1ORkVwMF9xdmUzNVNrOHlhZWpGYndj?oc=5" target="_blank">Towards rational design and optimization of near-field enhancement and spectral tunability of hybrid core-shell plasmonic nanoprobes</a>  <font color="#6f6f6f">Nature</font>

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Rational cell culture optimization enhances experimental reproducibility in cancer cells
Naturegeneral

Rational cell culture optimization enhances experimental reproducibility in cancer cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAzRUpJd0t2NzBsNFlwMVpmU2ZiUXhRS2U1XzVYc3RKcERSUmJzeG81NnI2WlhpcTNuTWl3VHY1MFpEYUpyTlNHdDNBTWxsWW1TbF9nOFVMWHl6S3ByYmRF?oc=5" target="_blank">Rational cell culture optimization enhances experimental reproducibility in cancer cells</a>  <font color="#6f6f6f">Nature</font>

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AI fragmentation-based optimization of Sorafenib derivatives targeting VEGFR2 for angiogenesis-related pathologies: a structure-based in-silico study
Naturetech

AI fragmentation-based optimization of Sorafenib derivatives targeting VEGFR2 for angiogenesis-related pathologies: a structure-based in-silico study

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8wZHA0YVl4aUNfZFVjVS1uN1RZRTdxLTB3dnJ4cEZnaEY1elBHTUIzbXhvU0ViYVN6alZ1RjhXamhXcUh3T24tYTNDWUYwaktOY094SUMwczZLU3U4TUpz?oc=5" target="_blank">AI fragmentation-based optimization of Sorafenib derivatives targeting VEGFR2 for angiogenesis-related pathologies: a structure-based in-silico study</a>  <font color="#6f6f6f">Nature</font>

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Hierarchical resource rationality explains human reading behaviour
Naturetech

Hierarchical resource rationality explains human reading behaviour

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5wNFBqcXVwZjdwV09zX3lXWC04YkwyTUx3Smk5Y2xlcHQyRldxOV84QlQyTTBvcFl2VDdwRE1GNFNDVkt1SEJvTlBrM0o5dTFmWDZpbG5naDROZEdYS3l3?oc=5" target="_blank">Hierarchical resource rationality explains human reading behaviour</a>  <font color="#6f6f6f">Nature</font>

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Rational synthesis of dual-atom catalysts for optimized thermochemical CO
Naturegeneral

Rational synthesis of dual-atom catalysts for optimized thermochemical CO

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9DYWpnazJwOURpbE1KWjN6RUYydFpSYmVQOGg5bWZEdWs5SzJNU0tlcklLY2hHUlY2MGxpeEVUSmE2NkloWnJGaTJhbjJ1dUp5SjRHTi10VG9vTUxNdnhV?oc=5" target="_blank">Rational synthesis of dual-atom catalysts for optimized thermochemical CO</a>  <font color="#6f6f6f">Nature</font>

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Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery
Naturegeneral

Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9pbUhoYW9uMDBUc0theVFNcnlDTXFpdVVTekQyaG9SaG13WmVVVkpKSFIwV3hLOUNPUlRONHZveVhmMkZpdWJJR1JlVUxzUHFQMEY0Q19XRmlXRENfMXF3?oc=5" target="_blank">Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery</a>  <font color="#6f6f6f">Nature</font>

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Rational Design of Type‐I Photodynamic Agents - Teng - 2025 - Angewandte Chemie International Edition
Wiley Online Librarygeneral

Rational Design of Type‐I Photodynamic Agents - Teng - 2025 - Angewandte Chemie International Edition

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE5OXzBtT3VJcVU1ajFydngxWEJjc0tvb24ySTlFQW9oLXlBQlJvbEM2RHFhRE5jZWdWWGFsMUdERVN0ejBPd0IwaEYxTHFvU2pMbDdUZWVJS1JELTM4RTJTc2M1VjBZT3JoNUE?oc=5" target="_blank">Rational Design of Type‐I Photodynamic Agents - Teng - 2025 - Angewandte Chemie International Edition</a>  <font color="#6f6f6f">Wiley Online Library</font>

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Rational design and modular synthesis of biodegradable ionizable lipids via the Passerini reaction for mRNA delivery
PNASgeneral

Rational design and modular synthesis of biodegradable ionizable lipids via the Passerini reaction for mRNA delivery

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE8yQzV1alEtaUFRc0hPRjlDUld0VXgyTnExLXlVeGVsWklTWVBGMXJKZHRnN084OVl4eDRqN3BwNUVKenlmSExMNVpqWnNURzRCLUgzNlpBc1VEWGF0?oc=5" target="_blank">Rational design and modular synthesis of biodegradable ionizable lipids via the Passerini reaction for mRNA delivery</a>  <font color="#6f6f6f">PNAS</font>

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Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b
Naturegeneral

Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1nR2FNYTh3QXcwNjU2Z0NCWEE0VXpmMkhGQVpFQnBNNzlTMFZpRkROVldmQXZyU1pkX2luVVkwdXZWUnA0SmVKU3Q3c0tDWTRUb3hmNTFvY1dHZUNJMk1j?oc=5" target="_blank">Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b</a>  <font color="#6f6f6f">Nature</font>

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The optimization of microbial functions through rational environmental manipulations
Wiley Online Libraryworld

The optimization of microbial functions through rational environmental manipulations

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE1ONWc4S2lpUTFmckNmUTVvZ0ptVWdfTnhHRS03bVJtbW9CRE9IYzJKc0dsRDVrcHlySFoyRHo5aUhhM0k4UWJ0NW4xMWJQM2dVWVh4NWwzcWs4Z3htVXIyZjhPQUVjUW84bEE?oc=5" target="_blank">The optimization of microbial functions through rational environmental manipulations</a>  <font color="#6f6f6f">Wiley Online Library</font>

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Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Wiley & Sonsworld

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTE5ianVJN1g0amtoZFRRX0h2eHBGalZhWW8yMUNhbkJYWHR5YThEMndvUjZEYkx4VUFKallxTFhiaWdyWGVlZFVDbHI5aWVWUDdzYTF5Sk9pTi1WampIMDBQSDhQOFFWdHBZZV8wZ29tUkpBSDFWSmc?oc=5" target="_blank">Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery</a>  <font color="#6f6f6f">Wiley & Sons</font>

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Ventus Therapeutics Announces Publication in Nature’s Communications Chemistry Describing the Structure-based Optimization of a New Series of cGAS Inhibitors
Ventus Therapeuticsworld

Ventus Therapeutics Announces Publication in Nature’s Communications Chemistry Describing the Structure-based Optimization of a New Series of cGAS Inhibitors

<a href="https://news.google.com/rss/articles/CBMijgJBVV95cUxOUHptNlgyOE5BZ2tiV3RGWnNEeG5EQ0tWTExPWnFvbXp1X18wdHlDdmpWNS1qOHFpeE83VkxjZWJFNWduQVRJZTZqdzRCdUtDWFdvNERab1U2aktvVndack9Hc2drYUZxbGZldjhMbUNLS0NlSVFsVjIyTW5PRmpzam9tUG84TzF5aGNQUDdJQ2VLZlotTkVrcjVjMTYyY1NVcEx3a0xwR3lLcnVnUXVlYU91cEFDbk9ZT0NIZVBodkpUR0x0RGdxajhFekoteTBxNjQtZXlnQUhfc3dNaEtsX1IxLXFBc3ZFUHpMMXp0cGpveFpTLVNkRE5yZ2JQOVVNZGN5YVo3aUdMZ05iY3c?oc=5" target="_blank">Ventus Therapeutics Announces Publication in Nature’s Communications Chemistry Describing the Structure-based Optimization of a New Series of cGAS Inhibitors</a>  <font color="#6f6f6f">Ventus Therapeutics</font>

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New insights into a classic membrane fabrication technique: an advanced NIPS theory empowers the design of energy storage membranes
EurekAlert! Science News Releasestech

New insights into a classic membrane fabrication technique: an advanced NIPS theory empowers the design of energy storage membranes

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFAwckxKeVMxcjU3YURuQ0lfZnZBMWxkWmptU2paQzlxbllCV2VrTFk5alhSd0pHUkJLVnJodGltdnBzekNONmxNZ1JnV2ctUTVmRzRLODNnRndzT3pG?oc=5" target="_blank">New insights into a classic membrane fabrication technique: an advanced NIPS theory empowers the design of energy storage membranes</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

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Rational engineering of Escherichia coli strain for stable and enhanced biosynthesis of pinene
Frontierstech

Rational engineering of Escherichia coli strain for stable and enhanced biosynthesis of pinene

<a href="https://news.google.com/rss/articles/CBMilAFBVV95cUxQNGpQZTN2WTNCM3NmcGVjYUN2RGM0WTFkTUNQbUhrdElWdWo1bmFlMGlVYjlLVDZWd2cwelo4cmNTckxha0VPVEdkX1lLTmRkVjdic3o5M0ZtTklkS3RmRnlZUXBoOHhUMW90X2NoV3B3RTdkZVBvVHhPdWRwREhIMUZIa1RicjE4emJQc3JqT19nMWFT?oc=5" target="_blank">Rational engineering of Escherichia coli strain for stable and enhanced biosynthesis of pinene</a>  <font color="#6f6f6f">Frontiers</font>

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