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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Polygenic risk alters the" (30 stories)

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Polygenic risk alters the penetrance of monogenic kidney disease
Lead StoryNaturegeneral
Dec 14, 2023

Polygenic risk alters the penetrance of monogenic kidney disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBPMW9MTlZXeElLb0VZRmhoc2huNEdBNkFQb1dTWHUxSTdJckhocjFsdmNvdU9mNFdlT3ZHaUZfaUlTcy1wTFYxWjNZRlJXNlhWaVFxMEV4Tk9JOU5IeWJv?oc=5" target="_blank">Polygenic risk alters the penetrance of monogenic kidney disease</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Polygenic risk alters the"

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29 stories displayed
Polygenic risk and rare variants in endotypes of idiopathic pulmonary fibrosis: a genetic analysis of population-based and case–control cohorts
The Lancetgeneral

Polygenic risk and rare variants in endotypes of idiopathic pulmonary fibrosis: a genetic analysis of population-based and case–control cohorts

<a href="https://news.google.com/rss/articles/CBMiiwFBVV95cUxPOE4zckthUTlKcTlMQWtCeFJxajJ3aFNnR0tMNzd4RE1XeUozX2g0NG1CN1Z3YVFydllKSkZXbkkwRnpMalVYQmFfOVJHdGZmZ1dZUjI2ZnNGQ0kybTFjNFEwS2lod3BLMzRWNnZQU1lKZXR3SXhRR2dsQXZOMDVhWHkxdm9ndVJKQS1n?oc=5" target="_blank">Polygenic risk and rare variants in endotypes of idiopathic pulmonary fibrosis: a genetic analysis of population-based and case–control cohorts</a>  <font color="#6f6f6f">The Lancet</font>

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Polygenic Background Alters Risk of Cardiomyopathy
European Medical Journalworld

Polygenic Background Alters Risk of Cardiomyopathy

<a href="https://news.google.com/rss/articles/CBMimgFBVV95cUxOZ3dtMWZRYlZldHdoSEZlemlTWHlQU3prTTV3ZkdjUXZWbW9LMDNZdG9UTXRBVmUzZi16c1lFT0pma2czdTRXd3k0WnItbTd4cU1xVWNWR2tqTkN5UnB0VEFDcl9pVXNSeGtJVkllbGJaaGt5UVZ1R3hsN0ZYSXFqclltX1BwOE8xN0k4aUNxREdjbDF4MWVIdk9R?oc=5" target="_blank">Polygenic Background Alters Risk of Cardiomyopathy</a>  <font color="#6f6f6f">European Medical Journal</font>

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Genetic Insights Shape Personalized Breast Cancer Management, Yet Variant Classification Uncertainty Persists
The American Journal of Managed Caretech

Genetic Insights Shape Personalized Breast Cancer Management, Yet Variant Classification Uncertainty Persists

<a href="https://news.google.com/rss/articles/CBMizwFBVV95cUxPLWQ1WW5OU1FCSmx4ZTZtS1FPRzJxVjVocHkzaGFPbUQ1QldEQ0dmSEw0Snl6UTZpRWJ6WnBaVVV4YzFFUkZtZHFZcnJmeHdoclVCZDVlMmhsRGo4WXBERmk0d0VGZUdxazk0eFhHNzZQc19RdmE1NW8tdGRxcFpQUlZvMDc4T3pXZzRkS0Z0aWpOajdLSVpKQS01ekZ5S1ZGNUVsRjk4MXExVjBGNkJScFExSGpXMV9aUWtET2tBdnFtNE1iajlOY3gwMmlUZTQ?oc=5" target="_blank">Genetic Insights Shape Personalized Breast Cancer Management, Yet Variant Classification Uncertainty Persists</a>  <font color="#6f6f6f">The American Journal of Managed Care</font>

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Somatic loss of the Y chromosome complements polygenic risk scores for type 2 diabetes risk prediction
Naturegeneral

Somatic loss of the Y chromosome complements polygenic risk scores for type 2 diabetes risk prediction

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5QNDZsTVBIUy1RbWpuNG42WnNPc3dlZWxCeFhPYXBNTW9EdmxicTdUNEE4SmI4Vkk3cFhQNUFla0ZzbVdnRnF2LUNXSDZOUzJ2cUhPd2Jud2ZoNjdOMlpN?oc=5" target="_blank">Somatic loss of the Y chromosome complements polygenic risk scores for type 2 diabetes risk prediction</a>  <font color="#6f6f6f">Nature</font>

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Silicon Valley sets its sights on building the perfect baby
Fortunegeneral

Silicon Valley sets its sights on building the perfect baby

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTE5SbjRWTzFSOE8xX252S0xfdFV0OVJVSUNfc0dHWVBBSUUyVUlDV0I4bXJqZWRCY0ZUalN3X1FPYk1yQTB1SG1ZMVRxZDkxZG9EX0ZLNTlwOXNHWlVtM19GT2dGRldsb3dqMjBqU0dQR3FzOC01VkE?oc=5" target="_blank">Silicon Valley sets its sights on building the perfect baby</a>  <font color="#6f6f6f">Fortune</font>

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Weighing scale lies: New study finds Indians face higher genetic obesity risk, but early action can reverse it
The South Firstgeneral

Weighing scale lies: New study finds Indians face higher genetic obesity risk, but early action can reverse it

<a href="https://news.google.com/rss/articles/CBMi1wFBVV95cUxOOV80V19ZcHhvdjFScm9JbE16WVgxcXFyUkpDcTJRNVYtU2VFZkgySzlGRXZkOVhPYlJmck9Ham1PS0U1UG1QX3pyeUpBU21lME5SdGhnSDlKT2dzcmh4c3Atdk1ZLVl0cFRIay1Ma1BGQW1iYVNrdzJrZGRxRW9UQjdoWVNfNzR5U1JObHlfVFlpWXpxaV84ZThlSGNtX1dPNTkzczI3bmlCME1WZWt4SVNXMFF4NGwzekZrREJaNUJPMVJDdVVCN1ZtdW5uNU5lLWpLdUstTQ?oc=5" target="_blank">Weighing scale lies: New study finds Indians face higher genetic obesity risk, but early action can reverse it</a>  <font color="#6f6f6f">The South First</font>

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What a Polygenic Risk Score Can and Can’t Tell You
Harvard Medicine Magazinegeneral

What a Polygenic Risk Score Can and Can’t Tell You

<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxOeTZoT3lrd2ZhYlRVQWNYOUsxeTVlcVBiQmkyMzZySmc2LW9JU0tDR3JiS2YyVFlxODNMR3pjM0drZkgzNkliRjJHODBBRFpZU0tZR3ljUHhXUXB4OXJEeVNYUWtYeHV5T3dKWWUzUUc0RU1tRTJOMUlISzhuckNheVZ1Yy1WN2tGRHVMYy0zQXUzVWc?oc=5" target="_blank">What a Polygenic Risk Score Can and Can’t Tell You</a>  <font color="#6f6f6f">Harvard Medicine Magazine</font>

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Maternal type 1 diabetes may protect children from developing the disease
News-Medicalgeneral

Maternal type 1 diabetes may protect children from developing the disease

<a href="https://news.google.com/rss/articles/CBMivgFBVV95cUxQN3ZPUi1NYVdfUDRSM2puaUppeEdoUE0tQzdqZldOcTFxMWZiYXFOM05jMjVWRU9pZnJ5Q2ZTSGFlZGJaS3hpdVdjMjFjeTlWd0pJV0hvb2dSbkEwRV9jenNEWTdZWWVqUVo0VmtKNTBCWFozT0FOU3p4WVNOZ3pKdFR2QWlPYzBaMlFJM000V2JZdlBTWmdPdVJaa1JNRVRuY0NVOEhyUVRlZHJVZ1hFOE9PU3hhc19JbkQxdHJR?oc=5" target="_blank">Maternal type 1 diabetes may protect children from developing the disease</a>  <font color="#6f6f6f">News-Medical</font>

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From Polygenic Risk Scores to Methylation Risk Scores: What are the Clinical Applications?
Centers for Disease Control and Prevention | CDC (.gov)general

From Polygenic Risk Scores to Methylation Risk Scores: What are the Clinical Applications?

<a href="https://news.google.com/rss/articles/CBMid0FVX3lxTE5vQkI3bTlsSFZKTnRtN0JiWWg3ZE5mSGpsQjJZNWlyRzR1S3Q4WWQ1em8wR0R2b2Zyc3V5SGE1Yk9NNEE4dUFqdnBqd091cGYtZXhIT1ZKVmhUU004M0RRMmFZcWpTMFkwX293em5DdXViSHBDeHNJ?oc=5" target="_blank">From Polygenic Risk Scores to Methylation Risk Scores: What are the Clinical Applications?</a>  <font color="#6f6f6f">Centers for Disease Control and Prevention | CDC (.gov)</font>

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Genetic variations interact with polybrominated diphenyl ether exposure to alter lipid homeostasis
Naturegeneral

Genetic variations interact with polybrominated diphenyl ether exposure to alter lipid homeostasis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE56N2JPb1dpbFJjSnU4YU5TaC1IZ2M1TllZVnlTWXFYVlI3eDNvS29OUC0xQ2ZkeXRoWG0wRHJfT0tPQ0pJV2E3T1VKbnR3cDJrVXdTRlFBT0pnQWRtWTBF?oc=5" target="_blank">Genetic variations interact with polybrominated diphenyl ether exposure to alter lipid homeostasis</a>  <font color="#6f6f6f">Nature</font>

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Plasma GDF15 affects long-term dementia risk and alters neuroimmune signaling
Science | AAASworld

Plasma GDF15 affects long-term dementia risk and alters neuroimmune signaling

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1nX3I5Sk5oYy1QeExRQy1QWjBiM1E3TlE0UXpESVVhVmpMaGMwQl9WRDhZWXE1bWpLdmczUVRfV29NemlFVTJfRkJMVXhrakpZYnNjXzhiMHNzTjU2c2h3?oc=5" target="_blank">Plasma GDF15 affects long-term dementia risk and alters neuroimmune signaling</a>  <font color="#6f6f6f">Science | AAAS</font>

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"Normal Genetic Test, But Still at Risk?" Brugada Syndrome's Silent Threat
3billiongeneral

"Normal Genetic Test, But Still at Risk?" Brugada Syndrome's Silent Threat

<a href="https://news.google.com/rss/articles/CBMibEFVX3lxTE5wUmdxb2I5NXphaGg1M0hZc0s3SDhTejlwNDJadTB0M1BQbXZUakhiUW9pMXpKNHBhUkVBV2thNEM4SnZpQ1dFRGZPZkZaVGVHd2NnZkZTM1V3SG8yWF9PVEw4V3N6Yk94Z3FQcw?oc=5" target="_blank">"Normal Genetic Test, But Still at Risk?" Brugada Syndrome's Silent Threat</a>  <font color="#6f6f6f">3billion</font>

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Common genetic variants modify disease risk and clinical presentation in monogenic diabetes
Naturegeneral

Common genetic variants modify disease risk and clinical presentation in monogenic diabetes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9idWhmVVhqVW0tcnZZMlkwdDQ1dXB2RkRPa0VScXdrendFR3FUNnZpOGwzWjViOS1zTG5uTnZWQ0dEZWJ5djNUTjEwVTI3ZGpkOE1sM1JhdWw0bjdrQ2E4?oc=5" target="_blank">Common genetic variants modify disease risk and clinical presentation in monogenic diabetes</a>  <font color="#6f6f6f">Nature</font>

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Instability of high polygenic risk classification and mitigation by integrative scoring
Naturegeneral

Instability of high polygenic risk classification and mitigation by integrative scoring

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ldUxhdmtEMUhOMXdKalNqX0tUcFFsRExST1BVblBoaW1pV2kzLVZ3MWlQNkdPbzh4bXFSaFRPUGRic3ppb0QwUk92aEtzMDRqS3YtZmwzYVFoekZCU0Z3?oc=5" target="_blank">Instability of high polygenic risk classification and mitigation by integrative scoring</a>  <font color="#6f6f6f">Nature</font>

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Heritable polygenic editing: the next frontier in genomic medicine?
Naturegeneral

Heritable polygenic editing: the next frontier in genomic medicine?

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBKb0F3NGFHaEdvY0t2RURqR19yby1UTHl2c2xzcmtXUGJCZ0thS0trbG5fREF5MVM2dUQ0Si0ybXQxX1NVblRGb25DUGthVWx0TzJFMEZuTUVZZDJWdHUw?oc=5" target="_blank">Heritable polygenic editing: the next frontier in genomic medicine?</a>  <font color="#6f6f6f">Nature</font>

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The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Naturegeneral

The role of polygenic risk and susceptibility genes in breast cancer over the course of life

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB5U3Bwemt0NWNZQmdiTUxkSnVIZ21scml4R2dObktzazJwRlFUWjVhMW5LQ09rY01ndTVNc25IZGh4YTFTNF8tbDJYa1V5VDJRQ0dqYTEtaVFKZDdmbThJ?oc=5" target="_blank">The role of polygenic risk and susceptibility genes in breast cancer over the course of life</a>  <font color="#6f6f6f">Nature</font>

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Gene-gene interactions between a LMNA variant and common polymorphisms drive early-onset atrial fibrillation
Naturegeneral

Gene-gene interactions between a LMNA variant and common polymorphisms drive early-onset atrial fibrillation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ZNlR6OXIwcGUwcThfNEV6cmFFaWFEcE1nS0xDVFBQZ3FFN0ZGc1hQZ0ItYmUxRXhEc3UwbXk0c0d0VHRZb2h6U1M2c0cxd1ZqdkprR3I5SV9JbDdLeHow?oc=5" target="_blank">Gene-gene interactions between a LMNA variant and common polymorphisms drive early-onset atrial fibrillation</a>  <font color="#6f6f6f">Nature</font>

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Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics
Naturegeneral

Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9idWZPMmQxdGFPenNzTklJdHh6bmtSbkE5TkZzS0wxVzZud2RPUFpEV1hjeGRaaXBiSVVKSy1GNmRwVEIyVlo4R1JRcnlUb3EzdVhKaHdncVl3dmtFdFUw?oc=5" target="_blank">Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics</a>  <font color="#6f6f6f">Nature</font>

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Analyzing complex traits and diseases using GxE PRS: genotype-environment interaction in polygenic risk score models
Naturetech

Analyzing complex traits and diseases using GxE PRS: genotype-environment interaction in polygenic risk score models

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5BSzRDTjJ6MldsODV6SUNjd1FEdld6V2daWk04Y1cyangyOUUyemplQ1FKX2lPMWFuTXlXT0VzdFltWHlGVWpSVW8tOTkzS0JFRFNTWU9PSjU0elZ6bUFz?oc=5" target="_blank">Analyzing complex traits and diseases using GxE PRS: genotype-environment interaction in polygenic risk score models</a>  <font color="#6f6f6f">Nature</font>

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Associations of Polygenic Risk Score for Late-Onset Alzheimer's Disease With Biomarkers
Frontiersgeneral

Associations of Polygenic Risk Score for Late-Onset Alzheimer's Disease With Biomarkers

<a href="https://news.google.com/rss/articles/CBMimwFBVV95cUxNRk1Kcy0wdGNHcnpOZW5qUnZ0VEJNRUxnS2tjdnBMWmpBdjYwWWdlZlVxOVZ1d3lFODU5bElIaEs1ZzBMUjBnWG5FMUQyZUNOb05ISHFaNVhVczNWQ000dm55WGh3ajlLYzNkYlhrSzE5amNVWDNfR2dMV3ZnU2dZTDNZNmFicUUwN3l2eWgxcVI0VzVjeENTYnNKTQ?oc=5" target="_blank">Associations of Polygenic Risk Score for Late-Onset Alzheimer's Disease With Biomarkers</a>  <font color="#6f6f6f">Frontiers</font>

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Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications
Frontiersgeneral

Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications

<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxOX0RwczlRWnBzQkRvanRuUXBBVDM1N3NkRFY0LTRxN0JYQ1FlZGZVbkFfSDgwVGMtWnN1RVQwaXhYRXM0enhpVkVsdFVaQlJxcVlhVmZzZTBsRG55aGI0TFg2WjFHQ29VOE9vLTFEZG5JdUNubHpkTElsVld4MVRVZC15bnZkTHJ1QVNRX3o4d2VJWk0?oc=5" target="_blank">Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications</a>  <font color="#6f6f6f">Frontiers</font>

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Genetic Susceptibility Modifies Relationships Between Air Pollutants and Stroke Risk: A Large Cohort Study
American Heart Association Journalstech

Genetic Susceptibility Modifies Relationships Between Air Pollutants and Stroke Risk: A Large Cohort Study

<a href="https://news.google.com/rss/articles/CBMickFVX3lxTE5ZVDJtaDNadmlmRkpYdkdWTnRYRVFlRVVmWDBqZEl5TE1hb3lSWXQzTTZ4endKUkoxZDBBUVZ1NTBjS0hEaUdaMEhWUjR0bm9uZlI5VzVUTjVoTnhJWVdLNi14anZmU2FweHI5U2JuUE9MZw?oc=5" target="_blank">Genetic Susceptibility Modifies Relationships Between Air Pollutants and Stroke Risk: A Large Cohort Study</a>  <font color="#6f6f6f">American Heart Association Journals</font>

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Genetic susceptibility modifies the association of long-term air pollution exposure on Parkinson’s disease
Naturetech

Genetic susceptibility modifies the association of long-term air pollution exposure on Parkinson’s disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5lSFpYeHZWTlI4WWlzMUdJZ0M4R1NFTnlvak03MlhQbm1ydU9DX0xDSW9qXzZxSXdodnM2eU8zZloxbVBfQ0t3dEdXalBKdnVvOGVuWjlFR19ObVU5Rmpv?oc=5" target="_blank">Genetic susceptibility modifies the association of long-term air pollution exposure on Parkinson’s disease</a>  <font color="#6f6f6f">Nature</font>

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Genetic and environmental risk factors of asthma: a narrative review
Frontiersgeneral

Genetic and environmental risk factors of asthma: a narrative review

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPYk5EU2puLVhyaEhEUXJTU3BORmxXM0VoNnNkRGNYcEpLdkRBMnBMa0R5cmIwUHFYOGg1dG1FdG9BOFVpV3hJRDd0Tm5wTWRFNkVRRUNkaHJDWV92VVpoMy1tQTd2NFo5SklmcUdqdDM0cGZIMHFfVzVJNnc3YUVYdUViSm0yOWVzWndRQllUOHVvQQ?oc=5" target="_blank">Genetic and environmental risk factors of asthma: a narrative review</a>  <font color="#6f6f6f">Frontiers</font>

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Biological aging and generational shifts in early-onset cancer risk
Naturegeneral

Biological aging and generational shifts in early-onset cancer risk

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBLcXFKN2NoVV9CZWVVckJBc0VodTQ1UGpVc3dQS2RvY2p1NEJXeVBxZXh3UXV5V0VCcml4dVR1a1FjZ1BxTVNMRlI3OHMzM3Q1dzVFbWN5emtSVXpPbEpn?oc=5" target="_blank">Biological aging and generational shifts in early-onset cancer risk</a>  <font color="#6f6f6f">Nature</font>

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Impact of gene-environment interactions on atrial fibrillation and cardiac structure
Naturegeneral

Impact of gene-environment interactions on atrial fibrillation and cardiac structure

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBMQWtXWS05N1c4dzhOSVRUanhJdTl5Zzlqcl84VlR5Z2YyNmpGaTJWajRCNEJHNE5PcldqZ0R6QkNPRmVTOGxaNll1V2pDQ2xtWVZtNTByWXdSVndrTEVB?oc=5" target="_blank">Impact of gene-environment interactions on atrial fibrillation and cardiac structure</a>  <font color="#6f6f6f">Nature</font>

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Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life
Naturetech

Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBQa3cyZ2Z1WGxoMjlwMTUxendfd0hwM244TEo1VmtWU05USmVHY21DOEFyeFBGMjhFaVAyUkJ6WlZkaVlfWHFiTWFOdFJRSm5KeThaVVQtS2pMOEQwRlQ4?oc=5" target="_blank">Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life</a>  <font color="#6f6f6f">Nature</font>

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Genetic modifiers of rare variants in monogenic developmental disorder loci
Naturegeneral

Genetic modifiers of rare variants in monogenic developmental disorder loci

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE16ekRJdDIwQlJBUWlheTdGSWh0NWk5eUFEaDJzaW82NmRHdnY1LW5OVEhMaUI4WW9NcEplUnNkeF9iUlF1X19VQjJiUmN1SEQtcWZ0Q3pwWnAtZDdSaU9J?oc=5" target="_blank">Genetic modifiers of rare variants in monogenic developmental disorder loci</a>  <font color="#6f6f6f">Nature</font>

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The therapy-conditioned host: a state-transition framework for second primary cancer evolution
Frontiersgeneral

The therapy-conditioned host: a state-transition framework for second primary cancer evolution

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxPNS00U1lTUERQZzFrWmxEbTJTS1ctSjIxVGJEZkpFejRCbnd6OFFWZWdVNVlETnozZXZKQlhZNFFaSzZSY3RLV1lCSW9xWlNDR3dzc3VkQWNIMHZxdlZ4MzdTeWdvemR5d3FLNlNESS1CM1BVNFAycmxEcDNCbnY3TGtRZ3k3RjRMdk5OQ1Jn?oc=5" target="_blank">The therapy-conditioned host: a state-transition framework for second primary cancer evolution</a>  <font color="#6f6f6f">Frontiers</font>

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