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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "One substrate many enzyme" (30 stories)

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One enzyme, many sugars: How a single protein builds a medicinal plant’s chemical arsenal
Lead StoryEurekAlert!general
Sep 5

One enzyme, many sugars: How a single protein builds a medicinal plant’s chemical arsenal

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1DTzU4OXFrby04X2tCQlJjN1JPNjdWVElOOEh3aGdoTURpLW5UdENOYTJkU0l6bWVUQnZtM2xxVUFnWGtmQmN5U2UwcWgyU0htODRoUzJjU0k0dk9O?oc=5" target="_blank">One enzyme, many sugars: How a single protein builds a medicinal plant’s chemical arsenal</a>  <font color="#6f6f6f">EurekAlert!</font>

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Search Results for "One substrate many enzyme"

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29 stories displayed
Decoding the substrate specificity landscape of a promiscuous enzyme through multi-substrate mutational scanning
Naturegeneral

Decoding the substrate specificity landscape of a promiscuous enzyme through multi-substrate mutational scanning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4temg3UVNlNjdLWC05VE9KWnhVczhyOEdsbEVNaEFxU2Q0VlozSkZDT243dmZhUlRFSFR0RnlrMlFCQjZMMU53NGplV0lmUTBvNk9HWjJyaVFhUzVSWmVZ?oc=5" target="_blank">Decoding the substrate specificity landscape of a promiscuous enzyme through multi-substrate mutational scanning</a>  <font color="#6f6f6f">Nature</font>

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One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse
Natureworld

One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBNQkhlY2pDdmphbVBhZ3hneUN4VlBSZU5nR3BuRk9fVjI3YVZ6RzZDMG5KdjZCS05FR0NnVjBIRTdZbDlKVW5uTWZWLXhWLTQxMnpwSGI4RjN4MXR5blhF?oc=5" target="_blank">One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse</a>  <font color="#6f6f6f">Nature</font>

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Single experiment can measure enzymatic kinetics for over 200,000 possible substrates
Phys.orggeneral

Single experiment can measure enzymatic kinetics for over 200,000 possible substrates

<a href="https://news.google.com/rss/articles/CBMickFVX3lxTE5WazYtNk10WkQ2c05JWC1jSWxiWmcyOGFUeVZjeW5BTU5CVG5RRG5qNFJQY2g3R1VmN0dwTXcyY1ZLWjBFTWw3Sk0wSjJTWk9jQnFib0NieG5rcFJkNnlka0laOUcwcWJvRjUzY19WVEN4dw?oc=5" target="_blank">Single experiment can measure enzymatic kinetics for over 200,000 possible substrates</a>  <font color="#6f6f6f">Phys.org</font>

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A substrate-multiplexed platform for profiling enzymatic potential of plant family 1 glycosyltransferases
Naturegeneral

A substrate-multiplexed platform for profiling enzymatic potential of plant family 1 glycosyltransferases

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5EbFBPMTJncG1QUlp3SXlCWVc4dEZzZThOaEgwcUhoLU9rV281N0lWZFdlLVZsNnVtXzNKazNEZml2R3Rpc2NpVGJuRXNES3hSNXE1VnVzbjQwMUZPVVJr?oc=5" target="_blank">A substrate-multiplexed platform for profiling enzymatic potential of plant family 1 glycosyltransferases</a>  <font color="#6f6f6f">Nature</font>

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A general model to predict small molecule substrates of enzymes based on machine and deep learning
Naturegeneral

A general model to predict small molecule substrates of enzymes based on machine and deep learning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5lcmx5d05BaVZQUEU0LVBVNmJXUkxOY2NXdmVIZ2wtdmYySi05ZmwyY01tY3F0d0E5QWt1RG9jOW1IeF9mV21TVkxlVUQwWW40djVuSmxudXdXSnN1Vkhr?oc=5" target="_blank">A general model to predict small molecule substrates of enzymes based on machine and deep learning</a>  <font color="#6f6f6f">Nature</font>

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Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis
Naturegeneral

Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBQbHYybnZGdGJXejcyaFRMdlRkQldtdTZON3Q3cXN5VFlFZmFQMFZMU3BzUkxjRU5UQWgzYVdpVUpJR3Y2TmY1RUNEb0JuQlZzdzVMLWF1NTkyRzJxN3dB?oc=5" target="_blank">Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis</a>  <font color="#6f6f6f">Nature</font>

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A structure-oriented kinetics dataset of enzyme-substrate interactions
Naturegeneral

A structure-oriented kinetics dataset of enzyme-substrate interactions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9HS0hyc0lVMVFUSUhuUDBVaWVJT1RSS0lFc2p3bVJPZlpUTDNJTmE0YzBJMllObGQxdFZFVTVtUDBtQk54WVZoVXdjUFo0SFdLNWlkNGhFWEp4cWQtOWFR?oc=5" target="_blank">A structure-oriented kinetics dataset of enzyme-substrate interactions</a>  <font color="#6f6f6f">Nature</font>

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Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages
Naturegeneral

Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9xd3djdFJRVF9kdFNZM3FhRHJXWXkzUy0yVlBPR2ZLeUZhNVkyeWhfTExlNlBZNUt2NkNBbXlFbzRjQzQ1YlFwc1NCSFF4akg2M1RpaHRVdF80ODMtWkVj?oc=5" target="_blank">Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages</a>  <font color="#6f6f6f">Nature</font>

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Accelerated enzyme engineering by machine-learning guided cell-free expression
Naturegeneral

Accelerated enzyme engineering by machine-learning guided cell-free expression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9jZUhGQzlmMDFpbzJjU3dubld2RHRLcDVYdmhFVVg1T1BKaEdadVFfR2M1bTZmVEt1RFVqdmJWVXpUTE1rZGQ3NmJ5czF5aWZxR2QzaDZ2MENOcWQyazdF?oc=5" target="_blank">Accelerated enzyme engineering by machine-learning guided cell-free expression</a>  <font color="#6f6f6f">Nature</font>

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Robust enzyme discovery and engineering with deep learning using CataPro
Naturegeneral

Robust enzyme discovery and engineering with deep learning using CataPro

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5nREY1UmY2d0M0eFBFQ2dvNmRfd1pZelVldHd5SEoyeHJRSmVCN0dRTGZsc0Z1Y0tVMmdaWG9fVllUWXd6QnNjM283ZkJSQkdCQ0lFeUM1YlIwcGR2N01Z?oc=5" target="_blank">Robust enzyme discovery and engineering with deep learning using CataPro</a>  <font color="#6f6f6f">Nature</font>

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Connecting chemical and protein sequence space to predict biocatalytic reactions
Naturescience

Connecting chemical and protein sequence space to predict biocatalytic reactions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5WQ1hQUjE2N01rRFlnbjJxX3hRclQwUHM0VTdnNEQwT2hkVXFYMEhva05aRGt5UnFNZnZnRGNYX0RoV0VxLXRWV0p4anpiR1g2bmk1ZkVRcTFCcEZ3bVZ3?oc=5" target="_blank">Connecting chemical and protein sequence space to predict biocatalytic reactions</a>  <font color="#6f6f6f">Nature</font>

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β-Carotene alleviates substrate inhibition caused by asymmetric cooperativity
Naturegeneral

β-Carotene alleviates substrate inhibition caused by asymmetric cooperativity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB2MndXRFhhSHBrcmg3MjY1eDRwaW9mZDB2Q0RTYVRfMXI0b1pmWmRQWE1Jb2VPTkRqb2xMNldGTkdjb01SeUZzMDRPYzY1T3hKN1pTMmlDUWloX0RncGtZ?oc=5" target="_blank">β-Carotene alleviates substrate inhibition caused by asymmetric cooperativity</a>  <font color="#6f6f6f">Nature</font>

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Nanozymes expanding the boundaries of biocatalysis
Natureworld

Nanozymes expanding the boundaries of biocatalysis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBUTlRkRW5UNzJYd09XcTF2T1ZHR3ZRelJHM2tBaEs1eUNKd0dvQVEwa3Iza1dTTWRQTkMtX3B4a1AwQzZMa2dWdUttVG9KRHk5T0ZMc2F4eGN6eVQzYzQw?oc=5" target="_blank">Nanozymes expanding the boundaries of biocatalysis</a>  <font color="#6f6f6f">Nature</font>

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Thermodynamic principle to enhance enzymatic activity using the substrate affinity
Naturegeneral

Thermodynamic principle to enhance enzymatic activity using the substrate affinity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAzdGUzdUtPaFNRX1lKVmc1YXBkNmhsVTNxMmtGWndSYW0xeExrVkUxS0dYRHFvUXhKMlh4RzNKbTE4R1B3Smwta2RGcXkwYlRQbkpSUk1hWTlSaDROOTNr?oc=5" target="_blank">Thermodynamic principle to enhance enzymatic activity using the substrate affinity</a>  <font color="#6f6f6f">Nature</font>

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Deep learning-based kcat prediction enables improved enzyme-constrained model reconstruction | Nature Catalysis
Naturetech

Deep learning-based kcat prediction enables improved enzyme-constrained model reconstruction | Nature Catalysis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1GMGtuNTRYRkItNXJpTXRRWkZTZFNueHhSSXNYQTBjVnBLQ3RnZUlneWdsdzY1b0pXRHlzaFlhR1g2OV9fWmdoLS1oMTVOODlxZzBrMTNrZFdHNHdmeE9R?oc=5" target="_blank">Deep learning-based kcat prediction enables improved enzyme-constrained model reconstruction | Nature Catalysis</a>  <font color="#6f6f6f">Nature</font>

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Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions
Naturegeneral

Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBGNEttb3cxNlMzM3E3WWYtckRtTlRzX1RmQlpoTC1kRmx4Z3Zua0ZvQlpFYktlMEF2UGNWVUdVd3luVFlPMHAxb2Nib21MbG9wYlhBbWtXcGRRamlkZVdB?oc=5" target="_blank">Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions</a>  <font color="#6f6f6f">Nature</font>

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Substrate scope expansion of 4-phenol oxidases by rational enzyme selection and sequence-function relations
Naturepolitics

Substrate scope expansion of 4-phenol oxidases by rational enzyme selection and sequence-function relations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9JYlBaTm1FZDBtSGl4Ti1PekJQRVRvbEc5cHlub040ZkMxQ3lzb1Q3aTVJTTFERlNObXc0aWR6TEh4UW0waVQ1MTEwWC0tT0U4Nk5ueWI0Z0g5b2JGN3d3?oc=5" target="_blank">Substrate scope expansion of 4-phenol oxidases by rational enzyme selection and sequence-function relations</a>  <font color="#6f6f6f">Nature</font>

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System-wide identification and prioritization of enzyme substrates by thermal analysis
Naturegeneral

System-wide identification and prioritization of enzyme substrates by thermal analysis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9ZN3kzZ2VMMjNxdEZjOW5VelRWSWZkTG5UcXEzSXg0bTBWZ1pxbkY2Y0t5WTlhU09fbjlPRHUzQXE2emFzb3l1NkMxSzJ5Tl83UFA1bUl2MmNmTXAzVTVB?oc=5" target="_blank">System-wide identification and prioritization of enzyme substrates by thermal analysis</a>  <font color="#6f6f6f">Nature</font>

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Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release
Naturegeneral

Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE82YThTN09udjFneTRRTHAwX1VVUWt6UmdzeTBaWVU5d05iZFh1bjNod0FqYUJFc2tOS2hCOWdWUWh5a1A0ckVDbGhlNlBWNHJ1WGJ2MXVkbGxMOTA3d3pr?oc=5" target="_blank">Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release</a>  <font color="#6f6f6f">Nature</font>

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Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration
Naturegeneral

Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5VOThtZmtwRXRhOXFvdDZiZERLN1pWTktxaHZsWm96T0djNXpHUkgzUkNGM2lZSkdVX1ZyM2lEQ0Jaa1ZvUW5GU2FnNWlUOFl2MFlNOV9nQ3MxX1FMT1Vr?oc=5" target="_blank">Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration</a>  <font color="#6f6f6f">Nature</font>

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Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family
Naturegeneral

Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBEQUNLZDY2T1N1bllEdVl6dUZDZk5xWENueVVFZGs5YW1vSXd0MWwtbm5lei1QVHB3c1lOMXZlUmVJMm1GbjFWeXVCVW93WnVNTUR1U0cxbDF0SjliVXFv?oc=5" target="_blank">Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family</a>  <font color="#6f6f6f">Nature</font>

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UniKP: a unified framework for the prediction of enzyme kinetic parameters
Natureworld

UniKP: a unified framework for the prediction of enzyme kinetic parameters

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9Xcng1cnViM1JxdUwtRXpIY01DMWwyZHRlRXdrcTRXLVliQjZfaXVzLW5VdEhfYVotN2ZYVUVXZXB5X3FVUVhLdXZLVzVmYjJSaUJKV0RHd3d6ZXpLZ1BB?oc=5" target="_blank">UniKP: a unified framework for the prediction of enzyme kinetic parameters</a>  <font color="#6f6f6f">Nature</font>

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Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars
Naturegeneral

Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBjYkkzc3V5dWlKU0p2YzBZbUhoVTlYdEN5SllwdUdxZW8xWTFEZHg0MEQ4UmlYcFpBcmxZN2U0eDdvdU1icGM0cGhMaGVXUnJkb0taYTA2azZlWHV1aXhj?oc=5" target="_blank">Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars</a>  <font color="#6f6f6f">Nature</font>

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Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded
Naturegeneral

Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE5CWjRGd1ZCb2N4ZkVFWkE0T1UxeVJlM1VKVDlKM2Y2ZzktdWRfcmdhbndXWXlFMmJEclFTcHRHRUxNZlBnd1QzdDhkTm03OWNJc1VhWHZB?oc=5" target="_blank">Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded</a>  <font color="#6f6f6f">Nature</font>

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Modular multi-enzyme cascades enable green and sustainable synthesis of non-canonical amino acids from glycerol
Naturetech

Modular multi-enzyme cascades enable green and sustainable synthesis of non-canonical amino acids from glycerol

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5oV19nZ3AwOXdxTU41VDdHYVlOSlVWb04tYU5Mc29yR2wySW1FemF2ZHFpWEtEMHFQTWNTZGFIOVZuSk9VTHpQM2JqdmFwTGc1V0FsY0pMUXhjUG9RdXVj?oc=5" target="_blank">Modular multi-enzyme cascades enable green and sustainable synthesis of non-canonical amino acids from glycerol</a>  <font color="#6f6f6f">Nature</font>

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Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches
Naturegeneral

Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9KdmFDc1EwZXRHOG40eWxQWUhjSFVIRHdTT0ZzWmdERDh0WlRNeFpyWEE2TjhfV2FiNkZaRHpwdnZ6MG9KRmtWVnRtUHduUjYtajNrbVRVZ2VWdlZRMmVn?oc=5" target="_blank">Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches</a>  <font color="#6f6f6f">Nature</font>

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Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations
Naturegeneral

Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5jcWJ1M2VuSjh5UDUxeEhsLVNmb1l4NkdZUzdyUlZwT1dJYTNhZW1JT0VnaFRMakw3bGM2VFlZdnE4Q1hrS21xdmRnZi1vWkxibnA3TV9YeTZ5NmFEdGNJ?oc=5" target="_blank">Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations</a>  <font color="#6f6f6f">Nature</font>

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Energy Landscape Topography Reveals the Underlying Link Between Binding Specificity and Activity of Enzymes
Natureworld

Energy Landscape Topography Reveals the Underlying Link Between Binding Specificity and Activity of Enzymes

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE9rSzFoSnEyS0dkVU1sSG1JTDRnQjJvZnd3bmUwc05Cak92NEoxUzZ2cG5FSDdIaElfUTg3RWQ2aW5Xa3FITGhrcTdmR2NqeDRVTkI0?oc=5" target="_blank">Energy Landscape Topography Reveals the Underlying Link Between Binding Specificity and Activity of Enzymes</a>  <font color="#6f6f6f">Nature</font>

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Endoglycosidase assay using enzymatically synthesized fluorophore-labeled glycans as substrates to uncover enzyme substrate specificities
Natureworld

Endoglycosidase assay using enzymatically synthesized fluorophore-labeled glycans as substrates to uncover enzyme substrate specificities

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBxQW1HeHlJMmZzVW9xM1gxN2hOZGtPaVF1SExmOWNJVUVlZEViQlNPRk82eVBJUXZtMHNrRFFBTDN6QzljMWNiYnlmaGpJUVlmanNXbktBeEtoNWxxSk1v?oc=5" target="_blank">Endoglycosidase assay using enzymatically synthesized fluorophore-labeled glycans as substrates to uncover enzyme substrate specificities</a>  <font color="#6f6f6f">Nature</font>

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"One substrate many enzyme" — Live Google News Trends & Headlines