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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Mutations that enhance ev" (30 stories)

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Computational frameworks for enhanced extracellular vesicle biomarker discovery
Lead StoryNaturegeneral
Jan 14

Computational frameworks for enhanced extracellular vesicle biomarker discovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5LS0xYbFBCY2RBNEY0WmFncDB5bDByMmJ4aGh2aDhLZklYX2t6VUMwOGs0OFBGNkRQejdzVFROUWNTdjNmZlZwYkYybFZuVVB2WGZaV2FPbi00MFBydTU4?oc=5" target="_blank">Computational frameworks for enhanced extracellular vesicle biomarker discovery</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Mutations that enhance ev"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
Rapid directed evolution guided by protein language models and epistatic interactions
Science | AAASgeneral

Rapid directed evolution guided by protein language models and epistatic interactions

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTFBocHZMalZmd1dBOVJjYlVkMGZvbUxRQVBGdjIyVlVhVFlnZ0UtUFVKSFdYQVI1UzBvN1NQN2MxeUNNY1I3RFdiN2RyTlRCUTd5SnBiRGhSRlFQSnZZMlFRRA?oc=5" target="_blank">Rapid directed evolution guided by protein language models and epistatic interactions</a>  <font color="#6f6f6f">Science | AAAS</font>

Super mitochondria-enriched extracellular vesicles enable enhanced mitochondria transfer
Naturegeneral

Super mitochondria-enriched extracellular vesicles enable enhanced mitochondria transfer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5FZ05LTm9lbEtoY0tBYjFFblVHUnI4YkpSRFBkM3FxUUJGR3VKOEtNM3ZtRExWbHdLejJPZFkxTXZWVlpZT1AyVUZxQTFfQ2Q5UkxLMkVNU0V5dzFyU1hz?oc=5" target="_blank">Super mitochondria-enriched extracellular vesicles enable enhanced mitochondria transfer</a>  <font color="#6f6f6f">Nature</font>

Advances in extracellular vesicle (EV) biomarkers for precision diagnosis and therapeutic in colorectal cancer
Frontiersgeneral

Advances in extracellular vesicle (EV) biomarkers for precision diagnosis and therapeutic in colorectal cancer

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxPSDU0UGtRNi1RdjVjbWhZYkJGcGl2dFJxTVgtZ0VxSUw0Z2dpbG5kTEpTdmVhNGZVcElCWHhMOThyM3FZTm00TG9jbGpnRlZFTW1POU5hYXE0dlJaV0k4bmE5bW1fUE5UbEtEOVNHNno5U29oeUF3VC1KV2FONU9tSlNQU1h4MHJzcE1EWGp3?oc=5" target="_blank">Advances in extracellular vesicle (EV) biomarkers for precision diagnosis and therapeutic in colorectal cancer</a>  <font color="#6f6f6f">Frontiers</font>

Enhanced cGAS-STING–dependent interferon signaling associated with mutations in ATAD3A
Rockefeller University Pressgeneral

Enhanced cGAS-STING–dependent interferon signaling associated with mutations in ATAD3A

<a href="https://news.google.com/rss/articles/CBMiqgFBVV95cUxNMEtNbUM2Y19xRmJXa0xnZ2lzal9FT25uTloxWmhCWk9YM2xRZExOZmwydDNhYW5CY1VIUVZ5eUkzallqdVdMTllIZE5talpOUERiUlNKWDQ1TkZMRHp5QVJZRjI0YTJ5bUw3X3dLU2Nuc0tjY1dQOUU2elJUZnN0QTl2eGdhTzVQQVNrUWxuZzY0RGdybVlBXzNTd2wwSzlQMlI0LUw1c1RPdw?oc=5" target="_blank">Enhanced cGAS-STING–dependent interferon signaling associated with mutations in ATAD3A</a>  <font color="#6f6f6f">Rockefeller University Press</font>

Decoding IGLL5 Mutation-Mediated BCR Signaling: A Novel Mechanism of CD8
Wiley & Sonsgeneral

Decoding IGLL5 Mutation-Mediated BCR Signaling: A Novel Mechanism of CD8

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTFBtNUFjYTdROGxuYXVLa3BEQ2ZVVGxsNm4zSDM4RWUtbmppYTdjM3hFbUx1cWl2OWwzV1B5azBDbkwxMGsxX3B6amJRc2VrUVZacEwwc2pwUkg2YnNjYXlzN01mVjZJNlk1NW5qSUYxMXZyOE52Y1E?oc=5" target="_blank">Decoding IGLL5 Mutation-Mediated BCR Signaling: A Novel Mechanism of CD8</a>  <font color="#6f6f6f">Wiley & Sons</font>

Ribosome-engineered Lacticaseibacillus rhamnosus GG with enhanced adhesion and immune activation via surface moonlighting proteins | Microbiology Spectrum
ASM Journalsworld

Ribosome-engineered Lacticaseibacillus rhamnosus GG with enhanced adhesion and immune activation via surface moonlighting proteins | Microbiology Spectrum

<a href="https://news.google.com/rss/articles/CBMiZEFVX3lxTE01ckxSYXpzeDNpMzFJeGM1YXdNM1NXM1paZndiTGZGNXVFdE1XVUJaYy1xOUtlQnJPdXktWEVPcXB6WWh0V2UyazhLQ1E1SWt0MlhXUVg3aU5qMVVKQXp1bDY4YzE?oc=5" target="_blank">Ribosome-engineered Lacticaseibacillus rhamnosus GG with enhanced adhesion and immune activation via surface moonlighting proteins | Microbiology Spectrum</a>  <font color="#6f6f6f">ASM Journals</font>

A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease
Science | AAASgeneral

A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTFBtTFpYRERxZjFsRWZ3bnU4R3RpMWhmYllDZjRuY2RkeHVzdExxMVdvM0ZMRVlEc25PQzlWTWMyRWczOHNvVVF4WTNZcThQNzBaaW45MERpYVRKUlhmejdfejhYUQ?oc=5" target="_blank">A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease</a>  <font color="#6f6f6f">Science | AAAS</font>

Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients
Naturegeneral

Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ucDUtbXhSTGVxMGJCT1R6cWhKclJQSGFtX1BvODcyS3pqY2E5aW1GZDQyZFNfNWNrcVREQkFrZHRNaGY3bFE4TU1EaVlDbWhUaV9LWmNhTEF3ckFoY3U0?oc=5" target="_blank">Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients</a>  <font color="#6f6f6f">Nature</font>

Gain-of-function mutations in the catalytic domain of DOT1L promote lung cancer malignant phenotypes via the MAPK/ERK signaling pathway
Science | AAAStech

Gain-of-function mutations in the catalytic domain of DOT1L promote lung cancer malignant phenotypes via the MAPK/ERK signaling pathway

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBMVUkydXpZeTUwUHJaTFlSRmRkekhhT2dMakRUbXpHWUZVdm93RUUyeHRvNm1aLWVaSm5tS1EtZkJLbE9oaWFCSUdfRmQzVDM0bkM3MWY5VWl2Z19zTjJJ?oc=5" target="_blank">Gain-of-function mutations in the catalytic domain of DOT1L promote lung cancer malignant phenotypes via the MAPK/ERK signaling pathway</a>  <font color="#6f6f6f">Science | AAAS</font>

Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release
Naturegeneral

Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE82YThTN09udjFneTRRTHAwX1VVUWt6UmdzeTBaWVU5d05iZFh1bjNod0FqYUJFc2tOS2hCOWdWUWh5a1A0ckVDbGhlNlBWNHJ1WGJ2MXVkbGxMOTA3d3pr?oc=5" target="_blank">Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release</a>  <font color="#6f6f6f">Nature</font>

MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis
Naturegeneral

MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBNWEZHYWpzZ2dhTDJSRDJnbkpUaWtTY3FNbmhoc2ZBNkRhRmN4Ti1oTUFNY0RLY2hKOUVXQWY4STBUZnZIRDEtUHZmMHBoeUd5elRNUEYwU0tIVFFFUXd3?oc=5" target="_blank">MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis</a>  <font color="#6f6f6f">Nature</font>

Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
Naturegeneral

Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8yQWZLYUM1czhabnR6T3N2NXBBdTFHWi1xUHE5OWhzOElQSVZXbWwzTlNweWJtWmZfdnR6WURYREEzbHk4SGFETER0ODFJQ1ZpUjRVcmJKSjg3U19HRVJN?oc=5" target="_blank">Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform</a>  <font color="#6f6f6f">Nature</font>

Simultaneous enhancement of multiple functional properties using evolution-informed protein design
Natureworld

Simultaneous enhancement of multiple functional properties using evolution-informed protein design

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1WTlV3bzhzSktIbENXd0NFenVaQTdJLW1RTG9TMWk5SUhWVm5sQ2swX3FpZDlZZnEzV0ptN3cwdTBYd09tRjVzbFVfWVJzcVBfaUp3SlZxZm1QTzNhSjdn?oc=5" target="_blank">Simultaneous enhancement of multiple functional properties using evolution-informed protein design</a>  <font color="#6f6f6f">Nature</font>

Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species
Naturemarkets

Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9pZjk3V21IYUFMRlJEcnZXZG9FRWhzcENVX1drN2V5V29MdHdmN3RDMDBLZ24wUEhNS0xjdjhubERwMjVNZ1VHMkZkNEpBVTd3aDNRMzRwc0o4RHNkWmZJ?oc=5" target="_blank">Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species</a>  <font color="#6f6f6f">Nature</font>

Immune evasion through mitochondrial transfer in the tumour microenvironment
Natureworld

Immune evasion through mitochondrial transfer in the tumour microenvironment

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5FaWpkVkhJMzBnUEk3SnlTbzl3MlVUY21yY0tmeDF0alJWV0tSanIyWjFyNEsyMkRlX0NKZ0VKbTBYY1lXeVRFUHQzR0FmNWtTaXpMaFhkRWVIcnlHbGtz?oc=5" target="_blank">Immune evasion through mitochondrial transfer in the tumour microenvironment</a>  <font color="#6f6f6f">Nature</font>

A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans
Naturegeneral

A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE9iRzNNekVjLUpuVi1SMFc2cUozQlB5aFlzRkRSYUNhRXBPSVFDeUdVS203VmE4eVBJZ0ZBRk5mV3g0MFVEcEZhUzNBRjJRWXdaaVFV?oc=5" target="_blank">A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans</a>  <font color="#6f6f6f">Nature</font>

Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer
Naturegeneral

Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ySGFPSVQwTkxKYmtuRXpJc3ZJdTY3Z0YwQ0drS1d0Ym9ET2hHNEVJd2o1cTNwcERCeW9tR1NmQ3ZwOEIyOUxpMHVvYl9PUWJZN1UwUWhWNGxpZ0pmcGc0?oc=5" target="_blank">Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer</a>  <font color="#6f6f6f">Nature</font>

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
Naturegeneral

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBXaEc2QmE0VmY4SUNTaEkySEFXbnl6ME00cnFrdGhGNE9FVXB0cXZPSGVGUGh3MnZMX3pRYWZFMk82YV9rYkc1c1NRUTRfcnhPc1pkZ0czNzE5dFZwaEdv?oc=5" target="_blank">Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation</a>  <font color="#6f6f6f">Nature</font>

New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene
Naturegeneral

New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1USlRCUGtWNFdId3BEdEFjNEVNMkFxSi1xQXNPZ3hHMm5URnRhX0VIRmwtM2o1Y2Raa1BtWmc1OE9Rc1AxaHNvaUZpbmI2aUYwSHhTbUJPT09GMmxLUnpn?oc=5" target="_blank">New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene</a>  <font color="#6f6f6f">Nature</font>

CADPS functional mutations in patients with bipolar disorder increase the sensitivity to stress
Natureworld

CADPS functional mutations in patients with bipolar disorder increase the sensitivity to stress

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0xSnE2bU9mTlY2MUFCU0JQbWNjZnJNcUxpdVBTRFk3a2lzYjNwZXFBdVFsVVlleFZCUDVVOEFSbC1ndDJMc18yS2ZUMk5pdGk1QUxHcVBEaV81bUh0a1Y0?oc=5" target="_blank">CADPS functional mutations in patients with bipolar disorder increase the sensitivity to stress</a>  <font color="#6f6f6f">Nature</font>

Small RNA Toxin-Assisted Evolution of GC-Preferred ErCas12a for Enhanced Genome Targeting Range
Wiley & Sonsgeneral

Small RNA Toxin-Assisted Evolution of GC-Preferred ErCas12a for Enhanced Genome Targeting Range

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTE4tQlpGUVFGdnBGcWZvTDBjZUFwbnVqRlBCNUd2VG1lYlQ2dDdLazZRVWRfWU5aaFdLZWJ2RWxVVDVnRUowWlVWWTNpVTdrQTJ3bXdaZnJ4aVRUZlFvSmRNMDZEQWs0ZjZWazdfaDJ1Nnh0M1pPR2c?oc=5" target="_blank">Small RNA Toxin-Assisted Evolution of GC-Preferred ErCas12a for Enhanced Genome Targeting Range</a>  <font color="#6f6f6f">Wiley & Sons</font>

Null mutants of a tomato Rho of plants exhibit enhanced water use efficiency without a penalty to yield
PNASgeneral

Null mutants of a tomato Rho of plants exhibit enhanced water use efficiency without a penalty to yield

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1hQkNYNHBPS0k5RkJ6aWJpaGYwU3dmUFZnVGxOR2dCYnU0WDlYcHZxOURNaW10N0tyZWNCNW03eDB4QnRwRFFTbWVXa0tRbnNoemhHVFExWVlPOGpi?oc=5" target="_blank">Null mutants of a tomato Rho of plants exhibit enhanced water use efficiency without a penalty to yield</a>  <font color="#6f6f6f">PNAS</font>

Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacity
Naturetech

Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBUeko1SmlMYnBkOS1HMWVNakRGNkFoVHQ2NU9DU0M2V2xtT2Q2YTdnWnpTcnZhN2ktcXgwSEhVSFJ6M0xmb25BejNmVk1yVmp6amtESV90cXVkQTdOSGln?oc=5" target="_blank">Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacity</a>  <font color="#6f6f6f">Nature</font>

An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack K
Journal of Neurosciencegeneral

An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack K

<a href="https://news.google.com/rss/articles/CBMiV0FVX3lxTFBVejREWWNvcWVDYWI4S0JOcGFjeGhEQWFXT3ZDMjVNMUpUX2FDSXdONThmLUhuVWdYaXNDZGVqcXQwR1RURWMwYnEwajF4ZllrZXNOUWVEQQ?oc=5" target="_blank">An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack K</a>  <font color="#6f6f6f">Journal of Neuroscience</font>

Chloroplast genome editing of Rubisco boosts photosynthesis and plant growth
Naturegeneral

Chloroplast genome editing of Rubisco boosts photosynthesis and plant growth

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBfX3RYcmIwaUJvTUwzZ0J3eVdma2U2Q0VSLUtvTF9fUy0xYzJwWEJsWkdqNVVHNDFZVUpxbUcyR3BTNUJYN3Y1dnFjRVlJNU5yc3RHZm9HczJTMHVRX3Rz?oc=5" target="_blank">Chloroplast genome editing of Rubisco boosts photosynthesis and plant growth</a>  <font color="#6f6f6f">Nature</font>

Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria
PNASgeneral

Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFA0dWI0czdCbk4tQl9jRFFyR2F4R2oxRFBxSlVpckoyT2JSeHgwOHh5X040ZU9VTEItOHJ0S1Vnd180TjgwQVRQWHdwaFdORm5rS2JvUjNsRWpERGxa?oc=5" target="_blank">Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria</a>  <font color="#6f6f6f">PNAS</font>

Autoactive CNGC15 enhances root endosymbiosis in legume and wheat
Naturegeneral

Autoactive CNGC15 enhances root endosymbiosis in legume and wheat

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5VbEd2cXF6VmxzaXZndWoySUYyMk9aZ3RDZUpDckQzZm9xVVloZ29iQ2tXal9QSEdjUUZsNDhoNnpmVjZyVmx3a2c3Mi1qQmVYeWxFdk5QdlhhVGh0TEQ0?oc=5" target="_blank">Autoactive CNGC15 enhances root endosymbiosis in legume and wheat</a>  <font color="#6f6f6f">Nature</font>

Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
Naturegeneral

Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1EQlpPMjFRNmJ5SlN3QkNvQm9tR2l5bGxQalRCWkxUdkxtbWFUZ2o3ODNfRVg3Y05KVnp2WG42ZzRiS01BN054eGNoaGF1aDRrN25HcFJyQzFWVEg3RjRN?oc=5" target="_blank">Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations</a>  <font color="#6f6f6f">Nature</font>

S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia
Journal of Neurosciencegeneral

S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia

<a href="https://news.google.com/rss/articles/CBMiV0FVX3lxTE9Ma3BVOTQ3c2N0Q2JycGtXR3RYMjFjTzhmRWJpOHFVVi1xb081U2F1OWw0ajU3bS0tUkhQWFE1ZDN3cG1YVjlNQldmMXVzZmtVVlZ1TnBQcw?oc=5" target="_blank">S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia</a>  <font color="#6f6f6f">Journal of Neuroscience</font>

"Mutations that enhance ev" — Live Google News Trends & Headlines