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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Mitochondrial TCA cycle m" (30 stories)

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Mitochondrial TCA cycle metabolites control physiology and disease
Lead StoryNaturegeneral
Jan 3, 2020

Mitochondrial TCA cycle metabolites control physiology and disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFByVEZ3WE9GRG5oanNZR09ENmtuVVJVVDV2NXh4MEdGQTJHd25pT0RfZzhoWk1vS2QwSzA5c0dsd3VDLUlucVF2MUJkbkVMbEU0Y2ZheDdFamJPREtreEp3?oc=5" target="_blank">Mitochondrial TCA cycle metabolites control physiology and disease</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Mitochondrial TCA cycle m"

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29 stories displayed
Emerging role of the TCA cycle and its metabolites in lung disease
Frontiersworld

Emerging role of the TCA cycle and its metabolites in lung disease

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPVWVYeEJPai1jMG1KaTRLdjdUNkFnY25vWGlWWkJ0bUQ2WU8xajNGX014ZTlRekFpZkY3LWdFSXgtNXRjTnZGc3VGbEtYSWViQjV4S3hRWlpUVFJnTGdpWmRyS3FIX1JkWWptSXVVTWJfRTVpWnJ3THFyN3NlanBOSnUyY2FjZzdfV1lscWoxZ3JJQQ?oc=5" target="_blank">Emerging role of the TCA cycle and its metabolites in lung disease</a>  <font color="#6f6f6f">Frontiers</font>

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Thioredoxin, a master regulator of the tricarboxylic acid cycle in plant mitochondria
PNASgeneral

Thioredoxin, a master regulator of the tricarboxylic acid cycle in plant mitochondria

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE9YZXhjcXZ3cUFHdkJJWnpCTGNnb2RnZkhnMnFXeHBXSkRuYzh5Zzk1RDBSQW1aZHBnMDJCWFJSdVVZMUttb2FEcUV5VjF6SVNSVTVmNGNob0tOMEgx?oc=5" target="_blank">Thioredoxin, a master regulator of the tricarboxylic acid cycle in plant mitochondria</a>  <font color="#6f6f6f">PNAS</font>

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An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice
Naturegeneral

An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1jRlpSNjRNUV9ueld6TG9vZ2wya0lRYTctVENPbFZDUXFob1NkUVFDTGk4WTdpUTRTVEY1YW5tQ0hiU0tjR0ktQWdPVlpqQlZSam0tRHVKZFVQbFlaNkxr?oc=5" target="_blank">An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice</a>  <font color="#6f6f6f">Nature</font>

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Operation of a TCA cycle subnetwork in the mammalian nucleus
Science | AAASgeneral

Operation of a TCA cycle subnetwork in the mammalian nucleus

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9tNDI0VEdtY0RteUU5ZkJPVk02M1JGckdVbVlUTTEzSnNEUDRISUJyUlI3Zy1YejlkVDBWYjBYNFd3eHVkcjhLeXJNc1JCX1l4ZHBBemRkNTJpU2dvTlJv?oc=5" target="_blank">Operation of a TCA cycle subnetwork in the mammalian nucleus</a>  <font color="#6f6f6f">Science | AAAS</font>

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Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression
Frontiersgeneral

Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxQVThCdDJJMWJod1FZVzhhXy1jY0RwVzd3X3lTenpiVkVKblVWWE95NEZBcURCdERpVVhfdkw5bEF4OEJqTnVISExvSk5MbTB2ajZDdXNkamNPMmRsSGkxVVRtSEdfdGxmOFRXN3gyUEZ0S0FBUGpnXzREYjU3UmRuYm5wbzBBSzBfQ1VXSVJHNUVjdGtRZUJlZ2daUjJVdw?oc=5" target="_blank">Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression</a>  <font color="#6f6f6f">Frontiers</font>

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Lactate transported by MCT1 plays an active role in promoting mitochondrial biogenesis and enhancing TCA flux in skeletal muscle
Science | AAASgeneral

Lactate transported by MCT1 plays an active role in promoting mitochondrial biogenesis and enhancing TCA flux in skeletal muscle

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9fQVpkMHJ1YV9YMW9HX1JWcUF3amw4ODhkcWxjVlBFTTMxU0tpOF95ZmNxQWd5R25UcURLWXFlWXlSMExmcGdEcWpud3BjQXBrN21MNHI0UDI3Yl9qYVVr?oc=5" target="_blank">Lactate transported by MCT1 plays an active role in promoting mitochondrial biogenesis and enhancing TCA flux in skeletal muscle</a>  <font color="#6f6f6f">Science | AAAS</font>

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Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation
Naturegeneral

Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5Kd29YXzFka1pYeFcweDR6MUc5N2YxQ0VOZWxBb2x3NC1UaUg4ZnhHeG1sMXB3NGJLWC1hc0paTjAtZWtGaktQYzk0YzhYbGpuNEFHQW1SNFpaclNUT2NB?oc=5" target="_blank">Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation</a>  <font color="#6f6f6f">Nature</font>

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Role of amino acid metabolism in mitochondrial homeostasis
Frontiersgeneral

Role of amino acid metabolism in mitochondrial homeostasis

<a href="https://news.google.com/rss/articles/CBMirAFBVV95cUxOY0dUS0FOcDJ2SUlMM24xdHo2Nk5MUXR2QlhaSDRDWUdZT29vQllmaUdlTWtSdHU2RDU3bmRtdnZWcUNJTENkaHh6Q0Nhb2x3MVNqMTNTejhNRVZ2UVNmOTA0QzNRZDdjYi11SHlycWl3U2NlNXZFOHN4c0twTnFoSzZfVGx5RlpYNXFPazRjVDFjZkVtSDBQcDZSLU9jMGVFeklWblZMVnZVclRG?oc=5" target="_blank">Role of amino acid metabolism in mitochondrial homeostasis</a>  <font color="#6f6f6f">Frontiers</font>

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Light shed on a non-canonical TCA cycle: cell state regulation beyond mitochondrial energy production
Naturegeneral

Light shed on a non-canonical TCA cycle: cell state regulation beyond mitochondrial energy production

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5uUUUyUjdpSVlPYUVZMVY4RnVsaFVneVdnZDExbGd6XzRmajlEUThVbXhQa2J1bVNSWWtxVW5ud20wX3JqWDZwekZ1NGtkaWl0VmVud09QbG51Y1kwYkhB?oc=5" target="_blank">Light shed on a non-canonical TCA cycle: cell state regulation beyond mitochondrial energy production</a>  <font color="#6f6f6f">Nature</font>

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Mitochondrial dysfunction-mediated metabolic remodeling of TCA cycle promotes Parkinson’s disease through inhibition of H3K4me3 demethylation
Natureworld

Mitochondrial dysfunction-mediated metabolic remodeling of TCA cycle promotes Parkinson’s disease through inhibition of H3K4me3 demethylation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE56dXJPdjJyT1ZSdHJsSHY4WG5WbVBJTHlyZXFsckxVUWhaMzNsWXFGMlloLW9RYnVwcUducWJrcVY3QUZIMU51MTBXVVhtZzZ0NW96UDZtWElySGt6blBR?oc=5" target="_blank">Mitochondrial dysfunction-mediated metabolic remodeling of TCA cycle promotes Parkinson’s disease through inhibition of H3K4me3 demethylation</a>  <font color="#6f6f6f">Nature</font>

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Investigating the relationship between ATP synthase and the TCA cycle by crosslinking mass spectrometry
Naturegeneral

Investigating the relationship between ATP synthase and the TCA cycle by crosslinking mass spectrometry

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE13T2Y3Ym8tbm92TUlnM0tlZUlKVVkzT1NGYlJvSnJDZ0xqWjI1dDNSdmllTGtsbUx1bmFyakZXX3dqZEQ0VzVkYnhuME9oRFRVZ2FXMlJBYUh5c1lKZWo4?oc=5" target="_blank">Investigating the relationship between ATP synthase and the TCA cycle by crosslinking mass spectrometry</a>  <font color="#6f6f6f">Nature</font>

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Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions
Naturegeneral

Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5wbkNGdXpsOHFuNW1tc2VqRWN3MkNzSGV2NUkzaHUtUlNsMHo3cXRuSmNJa0h1MkNKNUVITS1zQnRRSjBOR05DQU1hcDRvWlhOTGFUNk9TYV9YQkJsQmEw?oc=5" target="_blank">Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions</a>  <font color="#6f6f6f">Nature</font>

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Mitochondrial complex I promotes kidney cancer metastasis
Naturegeneral

Mitochondrial complex I promotes kidney cancer metastasis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1pbXlYZGRUcEhhS08yZ1QtNjZqMXNkR1VmYjdBc2wyVzkwR0FDQ3p5SXVCdEQ1YnlweVVmdEoyUlg3TTFzNHprYnVVSGFhMmtMU3p3b1ZHZzQ4RmpBR2c4?oc=5" target="_blank">Mitochondrial complex I promotes kidney cancer metastasis</a>  <font color="#6f6f6f">Nature</font>

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Association of the malate dehydrogenase-citrate synthase metabolon is modulated by intermediates of the Krebs tricarboxylic acid cycle
Naturegeneral

Association of the malate dehydrogenase-citrate synthase metabolon is modulated by intermediates of the Krebs tricarboxylic acid cycle

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBIcEsyUkNBRDFmaHRxZng0MDJmSTIxZ3MxRTV1YTB0OGhQVnlrcEluVUwyVjREV3F6Tkk2Y0pPS2lMTklFeHpLSU1SUkhiem1SQzVlVlE2anYycTl2cldz?oc=5" target="_blank">Association of the malate dehydrogenase-citrate synthase metabolon is modulated by intermediates of the Krebs tricarboxylic acid cycle</a>  <font color="#6f6f6f">Nature</font>

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Mitochondrial metabolic reprogramming in diabetic kidney disease
Naturegeneral

Mitochondrial metabolic reprogramming in diabetic kidney disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1VLVNzQmIxTG5PQ29IcEkxNVk3Q2p2SWIyZmpaNHllenI0OXp5eW5SQU1WUWllSmltV2JRV1JJbi1kUjkxY0FRMFRKbmRpQ0ZjcU1TMmJsdlE5MkJkX3pF?oc=5" target="_blank">Mitochondrial metabolic reprogramming in diabetic kidney disease</a>  <font color="#6f6f6f">Nature</font>

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Bioenergetic biomarkers as predictive indicators and their relationship with cognitive function in newly diagnosed, drug-naïve patients with bipolar disorder
Natureworld

Bioenergetic biomarkers as predictive indicators and their relationship with cognitive function in newly diagnosed, drug-naïve patients with bipolar disorder

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE11dl9McmlIdGs4Sk05X2JFU0pmODRabVVBN1V4eVcxWk81dmZidkRWQUgwdUh1cU5Pekp2dkV6aHJyNEE1VDd2LVVuMFJTSHJXQ2xlM3lOR2R2eXN4WTdn?oc=5" target="_blank">Bioenergetic biomarkers as predictive indicators and their relationship with cognitive function in newly diagnosed, drug-naïve patients with bipolar disorder</a>  <font color="#6f6f6f">Nature</font>

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Dysregulation of mitochondrial α-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson’s disease models
Naturegeneral

Dysregulation of mitochondrial α-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson’s disease models

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1XQlZyUU9ocGVEbzJfY09FWWo1R2w2M25zVHB2R2EtOE0tYkxMajhiNVpRb1E0ci1xYUhCX1p3ZmJMeUxPY0h6Slh0aHVRQmJOODd1bWVNZTktQnR3Q1hV?oc=5" target="_blank">Dysregulation of mitochondrial α-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson’s disease models</a>  <font color="#6f6f6f">Nature</font>

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Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation
Naturegeneral

Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5pQVh0X1ByQlA5eFdtNE5DOUxKSnZoTlUwaU1YV3l2N0s2S2c4aURuNHJpbkdDQ3RCWWpqdUd1a3hsMmdnbTNxQXFiUGw2d2ZFb1Q3ck4wa3NzYXRsY21R?oc=5" target="_blank">Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation</a>  <font color="#6f6f6f">Nature</font>

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Inhibition of HDAC6 alters fumarate hydratase activity and mitochondrial structure
Naturegeneral

Inhibition of HDAC6 alters fumarate hydratase activity and mitochondrial structure

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE15UUozN1RkdktxdW9CSjFqWWtKMkE4dE1nUmlGamg1aWhPMThKVHllVWtLMVJ5c2FCbDR0Z3FGTnZuekxiM3IyRGt0NXRRd0I2RHdpNm9DZXFuOFUyWWhv?oc=5" target="_blank">Inhibition of HDAC6 alters fumarate hydratase activity and mitochondrial structure</a>  <font color="#6f6f6f">Nature</font>

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Nuclear translocation of mitochondrial dehydrogenases as an adaptive cardioprotective mechanism
Naturegeneral

Nuclear translocation of mitochondrial dehydrogenases as an adaptive cardioprotective mechanism

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9icFVjSzlPZGpmUXpscXlNeG4tQ2NwME1SUmdGTElBN3BzMk5pV2NCWmh3MXV1aEZJSTl6Ml9tTG42UEc2eG1MSE5NS0h0UkVwWC13ZDI0OUVOZzRsU3lN?oc=5" target="_blank">Nuclear translocation of mitochondrial dehydrogenases as an adaptive cardioprotective mechanism</a>  <font color="#6f6f6f">Nature</font>

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Regulation of plant glycolysis and the tricarboxylic acid cycle by posttranslational modifications
Wiley Online Librarygeneral

Regulation of plant glycolysis and the tricarboxylic acid cycle by posttranslational modifications

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE9QbU9Oem4zZGkyaHFfLXo4ZXJHNWN0R3lSZXV0MmdveDMtMHFiVmRyeVBobzdFZS1CRThEVm0yTlM5TmJCNF95dW5ILXd0RGJQU1psQzRrYnV1QnBIOGNGYzlCMG9QdVgtc2c?oc=5" target="_blank">Regulation of plant glycolysis and the tricarboxylic acid cycle by posttranslational modifications</a>  <font color="#6f6f6f">Wiley Online Library</font>

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Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response
Natureworld

Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBoRTdKYk02WFhxOGI5ekJraEZHT1dPaTVFLXo4ejRlX2MzTFFobFc1QVRQS2tnVTJqd3h6alhoS1NodUVBengtWFZncHNUVVQ5TW13R2VqWXA0V1BWTkNJ?oc=5" target="_blank">Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response</a>  <font color="#6f6f6f">Nature</font>

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O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth
Naturegeneral

O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA4aW1aMmNsLTd2WHROSHRlQnRQWHZwWmJqaDBIaGl3SExabDRKZE1LT3dSNmxqc1Ftbm1LUlFFdnkyLWxxc3JhTnQ3V3p2R2E1TDFUUUo3WXI1QUliZ3Rr?oc=5" target="_blank">O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth</a>  <font color="#6f6f6f">Nature</font>

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Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity
American Physiological Society Journalgeneral

Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTFBBSGRXT1AwMTlaa2FoaXVnUGFKNWFEamtsaW1SMVU5NVNHU18ya2d3YWtxMWVINGRPcFlmdndqOGwtMVpwd0g2b0ktLTVhVG1CdmdyUnVQV0o0OFNMTXpZT1pZQ1VyOFJtU0NCclhJUzMtd2NBemc?oc=5" target="_blank">Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity</a>  <font color="#6f6f6f">American Physiological Society Journal</font>

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Hepatic Mitochondrial Oxidative Metabolism and Lipogenesis Synergistically Adapt to Mediate Healthy Embryonic-to-Neonatal Transition in Chicken
Naturescience

Hepatic Mitochondrial Oxidative Metabolism and Lipogenesis Synergistically Adapt to Mediate Healthy Embryonic-to-Neonatal Transition in Chicken

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE00UHM0cnZoOVZVSmluYVhYRElvODFWeUdjbGgxdjdmdVV1dG9DbXpiOF9vSExVM0RpZVdlOUJUbVVGcEUxdkN0YXJZekxneFJLVEcyQlZ6THdVZ2txVFV3?oc=5" target="_blank">Hepatic Mitochondrial Oxidative Metabolism and Lipogenesis Synergistically Adapt to Mediate Healthy Embryonic-to-Neonatal Transition in Chicken</a>  <font color="#6f6f6f">Nature</font>

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Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner
Naturegeneral

Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBuVFJqMXhrZmpKMVFjU0dKWGdiMGFkNVBvZXh2cXRZVlBCZVZRdms0ekxTeFQwaVVUOFdpUER2aTd4WEJpaEttMDVoaHMxRlR2QURTT19PaXY5ckRBcmM0?oc=5" target="_blank">Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner</a>  <font color="#6f6f6f">Nature</font>

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Cadmium induces ferroptosis in mouse spermatocytes by activating the ROS–TCA pathway
Naturegeneral

Cadmium induces ferroptosis in mouse spermatocytes by activating the ROS–TCA pathway

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBIN1ZRLWZlZDE2NmFXOFlCOS1weGtnTjhQdkUwMk9SVk9HZTQzU0x6QXFldkt4Y1Q2c0dZTGtkRG5EeE54QnBrUlN0d2FNTDM4UmN0dlpxTHdOQkJxU2c4?oc=5" target="_blank">Cadmium induces ferroptosis in mouse spermatocytes by activating the ROS–TCA pathway</a>  <font color="#6f6f6f">Nature</font>

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GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression
Natureworld

GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5mXzFibWZYZ2ZvUkV6N1hjeDhNS3lZRmExMXczLWNWTF9SaThybjFVUThsc2dYS01zYWVDS2hUMmxIRnluQUFIQ2NPSWU1RGlGb29LWDBXUy1yNWJJUk53?oc=5" target="_blank">GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression</a>  <font color="#6f6f6f">Nature</font>

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Mitochondrial metabolic determinants of multiple myeloma growth, survival, and therapy efficacy
Frontiersgeneral

Mitochondrial metabolic determinants of multiple myeloma growth, survival, and therapy efficacy

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxOMGItQ0R2RjZfVFBxMzB1RmlOczh3REtSbGZ2NDRCaEx4U0NlVlZYUUxkQko4eVhKdVpZU2tWSkFFNVVFQjRqWXNtTU5NM1pvcnpuczFXSVVYT1BYaENHaWczLXFaVWxRbFBqSU9KRUpRaXBoa3dueHJMaFJBM2t3aGJJMDJweDZRTDE2eWZB?oc=5" target="_blank">Mitochondrial metabolic determinants of multiple myeloma growth, survival, and therapy efficacy</a>  <font color="#6f6f6f">Frontiers</font>

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"Mitochondrial TCA cycle m" — Live Google News Trends & Headlines