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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Methyltransferase METTL1" (26 stories)

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Methyltransferase METTL1 regulates MSC mRNA stability via m7G modification in acute pancreatitis
Lead StoryNaturegeneral
Jun 23

Methyltransferase METTL1 regulates MSC mRNA stability via m7G modification in acute pancreatitis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5DYk9kZHIwempsNTQzWnVKa0ladzlCcXN5eHFnZy1uNFZCbUs0NUFjaHlEelVia19tek9ISHQ2dThJMnVwdFlaSmpXX2I0dWpiVEI5amZBalk0WW9XZlpv?oc=5" target="_blank">Methyltransferase METTL1 regulates MSC mRNA stability via m7G modification in acute pancreatitis</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Methyltransferase METTL1"

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25 stories displayed
Substrate selectivity of the human RNA m5C methyltransferase NSUN2
Natureworld

Substrate selectivity of the human RNA m5C methyltransferase NSUN2

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9VY0JmVzBsVm9yR0tIT05lMkZrZXUwS3c1UF9BUTZXeVhDSW9jTUhLNy1vQVgxLWN1TlJLNjkzVkRQSlJOM0NfMjYtTl9oX254QmJGcWlzMFMtRnduZVEw?oc=5" target="_blank">Substrate selectivity of the human RNA m5C methyltransferase NSUN2</a>  <font color="#6f6f6f">Nature</font>

Upregulated m7G methyltransferase METTL1 is a potential biomarker and tumor promoter in skin cutaneous melanoma
Frontiersgeneral

Upregulated m7G methyltransferase METTL1 is a potential biomarker and tumor promoter in skin cutaneous melanoma

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxOWW5HLWVObzlHbG9hTDJFLVE1U2ZqQ0JDNU9qSGJKZDV5UjVoS2R1R0U5VWJXZy16Z2hfN29FUHk0bzNMUlpoTTVTMmxvdHA3Vmd0X0RqVlRqY3V3VkdEWXhqU05wendPcmswZlFNdkdUR3RKdG5YN1p5TzdMdENkWDZxa1NnRHJ3bUxScVQ2dzZNZw?oc=5" target="_blank">Upregulated m7G methyltransferase METTL1 is a potential biomarker and tumor promoter in skin cutaneous melanoma</a>  <font color="#6f6f6f">Frontiers</font>

The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4
Wiley & Sonsgeneral

The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTFBGUkwzVVE1NVZMeER2M2ozX0FrTVVER0p0SkxCajYyRmtrckh5eHRSZVkzd0VKelV6VHFxNmhBX29MM1VxRkIyVVl5alp6TEc3SmhlaWh2VnFkNElqNVl1MGl6SFNNRmIwSnhhcHJ0cWsyVzlsQ0E?oc=5" target="_blank">The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4</a>  <font color="#6f6f6f">Wiley & Sons</font>

The tRNA methyltransferase Mettl1 governs ketogenesis through translational regulation and drives metabolic reprogramming in cardiomyocyte maturation
Naturegeneral

The tRNA methyltransferase Mettl1 governs ketogenesis through translational regulation and drives metabolic reprogramming in cardiomyocyte maturation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5TQ3cxOUJlWWZ0cThfdEE1UFYxZmhMcnZqQ1VfTkdRTDNsbHpKS20zNzRSU1BxS21XY3JxcF9rTDdnbGVBMzY1RlBHWkZOLURGbnd3SklfQkdJRjJwTU9B?oc=5" target="_blank">The tRNA methyltransferase Mettl1 governs ketogenesis through translational regulation and drives metabolic reprogramming in cardiomyocyte maturation</a>  <font color="#6f6f6f">Nature</font>

METTL1 in human cancers: recognition of their functions, mechanisms and therapeutic value
Frontiersworld

METTL1 in human cancers: recognition of their functions, mechanisms and therapeutic value

<a href="https://news.google.com/rss/articles/CBMilgFBVV95cUxOT0pfeG1FLVJhMDJfQTd2TEVld1BsSFZIRGNwM2hZZWFfOHVSVmJXY1ZWVE96MjJiam93NHpNeS1KX1E2T3hQdmRzUlB5ZTd4c2hoTWE5OWJkOXp2b0lEdDdqOW10aWNzai1KZ2N5X2EtTjhnX1Z5elBiYVNVNkRGUFVnRDNDQzdiMjN1ZGFhUTBidkRZVlE?oc=5" target="_blank">METTL1 in human cancers: recognition of their functions, mechanisms and therapeutic value</a>  <font color="#6f6f6f">Frontiers</font>

Nanomole Scale Screening of Fluorescent RNA-Methyltransferase Probes Enables the Discovery of METTL1 Inhibitors
Wiley Online Librarygeneral

Nanomole Scale Screening of Fluorescent RNA-Methyltransferase Probes Enables the Discovery of METTL1 Inhibitors

<a href="https://news.google.com/rss/articles/CBMicEFVX3lxTE9nRmxXay1aVmpXeHktZWVxWlFYVW1EY1ZJdlEzZUFLVmdUWWJ1NExoc0d5SWNjOWt4UkZtN0IxLURKYS1XQ0N0SDJzZGhKalFNaGlVcG80ektkWFdYN1dhNWpGdDFDQzhJZ01NdFFELUw?oc=5" target="_blank">Nanomole Scale Screening of Fluorescent RNA-Methyltransferase Probes Enables the Discovery of METTL1 Inhibitors</a>  <font color="#6f6f6f">Wiley Online Library</font>

Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1
Naturegeneral

Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8tLWpRbDV4MEZadTktZFdEVU5vSURRaUZqYnowNFNNWEhneDEyUmVzZHN0cGt1NW9WTlFLSGppNDNiQi1ERERaUE9YR1ZoUDZOcVctRnZqOHVYTmZfZi1n?oc=5" target="_blank">Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1</a>  <font color="#6f6f6f">Nature</font>

METTL1 coordinates cutaneous squamous cell carcinoma progression via the m7G modification of the ATF4 mRNA
Naturegeneral

METTL1 coordinates cutaneous squamous cell carcinoma progression via the m7G modification of the ATF4 mRNA

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBIeXh0V1RJX3F3Z19oT1JHQW9LYTRGa1NMSGtCQWVoWnB1bVJqaGx0QjJPcnRlNy1ab3pJWmZPZENfbzNWNml6bXRndDlwbm12cm14c0J3TTBzcXFjTDJV?oc=5" target="_blank">METTL1 coordinates cutaneous squamous cell carcinoma progression via the m7G modification of the ATF4 mRNA</a>  <font color="#6f6f6f">Nature</font>

METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α | Cell Death & Disease
Naturegeneral

METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α | Cell Death & Disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9JaXF0ZlFnUXUxYkU3VFM0VWpBSi10Q0p0a3pnLThfZjBwRTFXTmM5ZUI5bTZzVGVZN09kTVhYa3pZZmVnUnltbFdzd01LWEkzLVF1WmF6ZHJUc09VckFN?oc=5" target="_blank">METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α | Cell Death & Disease</a>  <font color="#6f6f6f">Nature</font>

Identification of novel small molecule inhibitors targeting multiple methyltransferase like proteins against hepatocellular carcinoma
Naturetech

Identification of novel small molecule inhibitors targeting multiple methyltransferase like proteins against hepatocellular carcinoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAyS0RLQzhQMG5GNm84U2xNMUY5UVU4VFBCMFdja2FPLU1zVnFxQm0xeUtudXVUa3ZsbDlrY0c0S0EwZ1pSek1vaDRibm45cjBjY3dVOE1WaXJVczhaczRZ?oc=5" target="_blank">Identification of novel small molecule inhibitors targeting multiple methyltransferase like proteins against hepatocellular carcinoma</a>  <font color="#6f6f6f">Nature</font>

miR-193a-5p–mediated Inhibition of the METTL1/COX-2 axis is critical for Astragalin-induced apoptosis in cervical cancer | Scientific Reports
Naturegeneral

miR-193a-5p–mediated Inhibition of the METTL1/COX-2 axis is critical for Astragalin-induced apoptosis in cervical cancer | Scientific Reports

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBxdVhhOWVZUzFnaXNsRnVkV3pucnZJNUh6X2xBTEwtZU55bTZJc0FNS2gxaEU3bDRjSi01RnFrM0lvLVVWdVlDLU4tUXM4VFY2bk9xSzd1Rng3YTByZ0JF?oc=5" target="_blank">miR-193a-5p–mediated Inhibition of the METTL1/COX-2 axis is critical for Astragalin-induced apoptosis in cervical cancer | Scientific Reports</a>  <font color="#6f6f6f">Nature</font>

Integrative bioinformatics analysis identifies METTL1 as a regulator of immune infiltration and prognosis in breast cancer
Natureworld

Integrative bioinformatics analysis identifies METTL1 as a regulator of immune infiltration and prognosis in breast cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4yc3kwZUFoODZlMGVnWTk1YlFSU2pBTlplb1ZCaUZ0RnRHQVRZbWNFTmp2YTBTd2tUZUV3WmFwYmpmQ1dIX3NaM1p5amZwWm9xYVRGUG4xN3YzUWcxMUhz?oc=5" target="_blank">Integrative bioinformatics analysis identifies METTL1 as a regulator of immune infiltration and prognosis in breast cancer</a>  <font color="#6f6f6f">Nature</font>

G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster
Naturetech

G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1aNWpQMDV1UlMwdWFnUXRvWV9CZVFMMktfc2VNM29uM2ZmU2JTcDBERTlTYzI5MXp5Nl9CR2oyd2wzQ2xyRXJNREJDc1h0Q3NXSE5TNkk4ZnowR2NRVTRR?oc=5" target="_blank">G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster</a>  <font color="#6f6f6f">Nature</font>

METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m
Naturegeneral

METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1hY3dyQlAxMGRVUXNtaE5oNkYyVkxYOW13R3NBSGJwWm1xNmVEQW9KcHBObm1rUHRoVFh4bEhBQWJfNVJYeU5RZzNoMHBYQjlvNmt1SzR0XzNobU9rY2ZN?oc=5" target="_blank">METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m</a>  <font color="#6f6f6f">Nature</font>

RNA m7G methylation regulators and targets significantly contribute to chronic obstructive pulmonary disease
Naturegeneral

RNA m7G methylation regulators and targets significantly contribute to chronic obstructive pulmonary disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9iaWoyR2p3aDFIdUVhSkV3UjlpbVczX3A5MGY3QTUtYnlnN1JMWUtnd2JocFRYbnJyQ1NyQkFKcl9qLUREYnFaYmRrVW8wUWlwRlNTdXBseVJqcGt0cXZZ?oc=5" target="_blank">RNA m7G methylation regulators and targets significantly contribute to chronic obstructive pulmonary disease</a>  <font color="#6f6f6f">Nature</font>

Multi-omics integration of methyltransferase-like protein family reveals clinical outcomes and functional signatures in human cancer
Natureworld

Multi-omics integration of methyltransferase-like protein family reveals clinical outcomes and functional signatures in human cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9aRE1pX1BTSjFreklTV3k5Y2pRNVlVQnhFMkRkRUx0STFRNmxlQVZSNXpsQktrTWZLai15REV3a2YtdmduSkhRVV9NQTdsWDBiNExQeldlOHlDTWQ5cFVZ?oc=5" target="_blank">Multi-omics integration of methyltransferase-like protein family reveals clinical outcomes and functional signatures in human cancer</a>  <font color="#6f6f6f">Nature</font>

METTL1‐m7G‐EGFR/EFEMP1 axis promotes the bladder cancer development
Wiley Online Librarygeneral

METTL1‐m7G‐EGFR/EFEMP1 axis promotes the bladder cancer development

<a href="https://news.google.com/rss/articles/CBMiaEFVX3lxTE83bF9keHJxWGhSWDNieDgtVEVoS0hZQkZTWW5lOW85eVBJYkh0dlAzZDNUNnRJejlSWmNzcHlKV1JmQjh5ZG5uVXhlWGVDbDlETV9QSEdJcWltcjY2dGNDWnRhSUlGY1hf?oc=5" target="_blank">METTL1‐m7G‐EGFR/EFEMP1 axis promotes the bladder cancer development</a>  <font color="#6f6f6f">Wiley Online Library</font>

Targeting hyperactive tRNA modification improves anti-PD1 efficacy
Naturegeneral

Targeting hyperactive tRNA modification improves anti-PD1 efficacy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE15VTlqdGs5alY1eVlNdkxCOHVyRXNkOUw3UElQdjFabWlnZEZzRUNqaE1GTHdFNjZES0tiMFRock9YNUhNdTZhcXktUXFpbEY5Zjg2TEdjUUpnY1lqdXFN?oc=5" target="_blank">Targeting hyperactive tRNA modification improves anti-PD1 efficacy</a>  <font color="#6f6f6f">Nature</font>

IGF2BP3 promotes mRNA degradation through internal m
Naturegeneral

IGF2BP3 promotes mRNA degradation through internal m

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE82OFAzSXlQYTVuc19USlhlM1lMQ3ZIVUFNMEtlVTRGWERjMEtoRVFZVlZEZV9mSUFueEtQUTVWMXp4WVlLRWl0ZjNRd2hUSlNnT1FENTNmNmFlRVpIM0Qw?oc=5" target="_blank">IGF2BP3 promotes mRNA degradation through internal m</a>  <font color="#6f6f6f">Nature</font>

Dysregulation of tRNA methylation in cancer: Mechanisms and targeting therapeutic strategies
Naturegeneral

Dysregulation of tRNA methylation in cancer: Mechanisms and targeting therapeutic strategies

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5yM1NSZnpkYmFIcGhNNDJIbHdMMU14NzRQbS01QXRBaEpNNVNReXI0cVNKRDVqc3BRLUZRNlpuMnhRZUM2amZ6NlFKbmRSNGNXbVFYeDNlOWdvZWJYUld3?oc=5" target="_blank">Dysregulation of tRNA methylation in cancer: Mechanisms and targeting therapeutic strategies</a>  <font color="#6f6f6f">Nature</font>

METTL1 promotes colorectal cancer cell proliferation by attenuating CHEK2-induced G1/S phase arrest
ScienceDirect.comgeneral

METTL1 promotes colorectal cancer cell proliferation by attenuating CHEK2-induced G1/S phase arrest

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTE9UWVBNb2V5a2pCVUxSR0VVbE5kZ0ZRODlISnFxbUY2dGFnLVU3MW1CM2hORVpoWk5GZ0dKOXVWQlhPYUthZ2hJR1N0S3pjcnhZa01kZFBPQXZ3aklsMXAxc2lRSjNsSno1dXA0aFBDbGhrcEtxbkE?oc=5" target="_blank">METTL1 promotes colorectal cancer cell proliferation by attenuating CHEK2-induced G1/S phase arrest</a>  <font color="#6f6f6f">ScienceDirect.com</font>

Checks and balances
UT Southwesterngeneral

Checks and balances

<a href="https://news.google.com/rss/articles/CBMif0FVX3lxTE45T3lVUDlvWlBZMm1za2ticy1TVWxtT1luTEN2MU9VN1VvUzZnQW5lTHg5RjFyc25HYW9uck8yNDRBX0ZMMUEyNUZYN2s3cUtkdWFUak05a0lYZ2FvV1BnMDhtd1pwTWh3Zk9fTXlmVUgwdVB6SE50dE01MGFqMVE?oc=5" target="_blank">Checks and balances</a>  <font color="#6f6f6f">UT Southwestern</font>

Methylations in dilated cardiomyopathy and heart failure
Frontierstech

Methylations in dilated cardiomyopathy and heart failure

<a href="https://news.google.com/rss/articles/CBMiogFBVV95cUxNdk5qRU5KMWZhN3pXNFQ2alIwTEhqRm5vSnNDRzB2YUNMY0tOcTdvbmFtRjBXTkVoakpkVTQxUEhybDhrcHMyNGpkYmlDanhUQWR6elR5b1pCMDdFYkhXeDBUdE5ZTmJoUlUzMDhBcVZIbXBRSVV1UmRzWUxBMk9HdENDYURNN2hfcmRNWTRpWTcydFNSOTBqbUt6a0RRNEc5c0E?oc=5" target="_blank">Methylations in dilated cardiomyopathy and heart failure</a>  <font color="#6f6f6f">Frontiers</font>

RNA modification: Mechanisms and therapeutic targets
EurekAlert! Science News Releasesgeneral

RNA modification: Mechanisms and therapeutic targets

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE53WE5OWEtjWnJaTHpCUWJ6bEV3YTI3dmNKYVZGc3lPOTk5TW8yUE5PNENnelNVSms3LXlFVzFlQ2c5TUdQM3RYeFIxaWd1dDh3T3RDOVFPUWFkX3Bu?oc=5" target="_blank">RNA modification: Mechanisms and therapeutic targets</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

Prof. Kuang Ming's team and Prof. Lin Shuibin's team co-published an article on intrahepatic cholangiocarcinoma immunotherapy
中山大学SUN YAT-SEN UNIVERSITYworld

Prof. Kuang Ming's team and Prof. Lin Shuibin's team co-published an article on intrahepatic cholangiocarcinoma immunotherapy

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE5QcWN2MDFLWXktNW9fcExaQXRHa3ZuWDdMMkJpdEw5OGJWSzhCeDBEVnNSN3AzRnBoOFNfLVBBa3l2Rm9tUU9DT1hHN2l6aDFPVVlCSU5ieXBJVmtQeS1EZg?oc=5" target="_blank">Prof. Kuang Ming's team and Prof. Lin Shuibin's team co-published an article on intrahepatic cholangiocarcinoma immunotherapy</a>  <font color="#6f6f6f">中山大学SUN YAT-SEN UNIVERSITY</font>

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