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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Leveraging functional gen" (30 stories)

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Cross-species gene redesign leveraging ortholog information and generative modeling
Lead StoryNaturegeneral
Mar 3

Cross-species gene redesign leveraging ortholog information and generative modeling

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9KcEVpQ3p0c01HRDBZcHBSbzZkMl9jdTBPYmxDVGNqZDEtVFV0Ymh1VzJnckVYWmxwamFKbGZSZ25LODNsY0dicVhsakxDN2NDckxnWGctdWpsa0hEYWFB?oc=5" target="_blank">Cross-species gene redesign leveraging ortholog information and generative modeling</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Leveraging functional gen"

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29 stories displayed
From growth to function: Gene helps human heart cells decide when to mature
Medical Xpressworld

From growth to function: Gene helps human heart cells decide when to mature

<a href="https://news.google.com/rss/articles/CBMiggFBVV95cUxQS1BheEg5NDQ2clhyeEYxQlc0Y2xkWGhHZlljSzNhNklYWWhqRDlkT25GSlV1MDYwZGNTckFjdWgtbE9BOWNsWTRLVGlQUlQxX2QyTHNYM09Ua21Bdk1Gcmc1NWlSZ2dvSjR0LWx4VXhsX2hiS0NtaDBoUEUwRnNsWkpn?oc=5" target="_blank">From growth to function: Gene helps human heart cells decide when to mature</a>  <font color="#6f6f6f">Medical Xpress</font>

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Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain
Naturetech

Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1QQ01kSGhGYlFBM2tnX1BTaFR0VmRIc19mX2JqSm1vek9hcE4wY3JZdkdPVjF3Zlhaam9FdEdrTGY5ZGt2R1p0RzJnQWk2U2Uzci1SRFQwVmhOcjFRcHRV?oc=5" target="_blank">Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain</a>  <font color="#6f6f6f">Nature</font>

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From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases
Frontiersworld

From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases

<a href="https://news.google.com/rss/articles/CBMijAFBVV95cUxQYmc1U3BsQnM5dkdDcFpfYWNTQ2ZTZGhQdG5Sa24xWVJkMVVFRzJzbzFPUHR0aE1xZTlTTFB1dFEteVRPemtnd0VjZk4tcWN6MDFabUc3MlJJNmxFZ29VUTNtdUw1V1BnN3Z3c0IteW43UllFZmZMazd5c2U0Q0ZNbVhrZDczZU1tOEU3MQ?oc=5" target="_blank">From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases</a>  <font color="#6f6f6f">Frontiers</font>

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Leveraging genomic large language models to enhance causal genotype-brain-clinical pathways in Alzheimer’s disease
medRxivtech

Leveraging genomic large language models to enhance causal genotype-brain-clinical pathways in Alzheimer’s disease

<a href="https://news.google.com/rss/articles/CBMie0FVX3lxTE4wOEFLaC1zZGl3dXZwZldVMjdsMUhRNjE2MTRyYVpOdEt2b0wwU1RUWHBmMEVMbzFnU2ZZR1lERW01b3dEc2xnTlN0eUI2TzBfdHhmd3ZRcFJSS3ZsTUs3MC1wZEN0UE0zNUFENzloVlVkajAyWmZVN093UQ?oc=5" target="_blank">Leveraging genomic large language models to enhance causal genotype-brain-clinical pathways in Alzheimer’s disease</a>  <font color="#6f6f6f">medRxiv</font>

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Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co-pathologies, and sex differences
Wiley & Sonsgeneral

Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co-pathologies, and sex differences

<a href="https://news.google.com/rss/articles/CBMidEFVX3lxTE4tZmdqajlWVUgzVThrRDE4c2dEeG1pbDVHU1JhcjJiSjRYdGVIQnlQcjV4VkJRTURWV1Y5N05mS3FTQ3JKVWo4WlhPNmlDQjR3THBhbFEtaXN0eGUzLTRZTFdwRHE3SmUwa3lPRUxKZlFud2to?oc=5" target="_blank">Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co-pathologies, and sex differences</a>  <font color="#6f6f6f">Wiley & Sons</font>

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Semantic design of functional de novo genes from a genomic language model
Natureworld

Semantic design of functional de novo genes from a genomic language model

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9oUjF0Vk9DdHpfX2ZkcEdlLVdhMHNqU2JCOURialdmVXFHRUZSVXRWcVNkbHpBMjZNUVcwaEdWbDF4N1dNNGpKSWw0TGJhNk1zYnZ0eFUwdm9ZazBvcG5Z?oc=5" target="_blank">Semantic design of functional de novo genes from a genomic language model</a>  <font color="#6f6f6f">Nature</font>

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Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries
Naturetech

Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBCQVU0ZFFoakdPcmFPR2hnZmR3WV9rTGZQdkJobmZQaVVnZWpqcHo5U3M4bGI5Q1VwemlvektlcVZDUFdCLVlJNGJOdWNCX2JIVWtidjJZa3pHUFpwU2pz?oc=5" target="_blank">Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries</a>  <font color="#6f6f6f">Nature</font>

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FANTASIA leverages language models to decode the functional dark proteome across the animal tree of life
Natureworld

FANTASIA leverages language models to decode the functional dark proteome across the animal tree of life

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA2UkRLTEUyMzU5RjJMcTh5cms4STFfWS1kQXVQd1RibFlxb24tc2ZVa2JNOW9ZUG96WEM4WklTdGp6RlhZUkZsdEpZT3FJSHZpb0lOY3pidFRYSWJ3UW9r?oc=5" target="_blank">FANTASIA leverages language models to decode the functional dark proteome across the animal tree of life</a>  <font color="#6f6f6f">Nature</font>

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Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs
Natureworld

Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBMR2FwRXg2dzFNNWtjNkRlaHdTUHpkZ0I2WWgwSi1WMllmTTF2cElCOWE0c3NMUDFodzN0ekMtQXMwN2czS3FJeGE0eUdNVzZyVW1SQ2dNMzBYU3d3NVNz?oc=5" target="_blank">Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs</a>  <font color="#6f6f6f">Nature</font>

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Predicting genome-wide functional constraints with GPN-Star
Naturetech

Predicting genome-wide functional constraints with GPN-Star

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1SeURMczIzcDNlclNUeUxDX29RZENPSTV1WWdOWENrbHlWRFlSMDRNcGk2d1A2UUJoNG1TRXBPQ2RCZHRPR25rVFpHbkRmODZiMkpMMDlqMDA2UUZLTFJB?oc=5" target="_blank">Predicting genome-wide functional constraints with GPN-Star</a>  <font color="#6f6f6f">Nature</font>

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Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia
Naturegeneral

Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8xV3VuVGY2VzM1UjVUVkFwYkhlYm5yWkctd1J4dlRCbC0tNGhxMktrT3IxWmYzYjZwUVFDZnduWlktbEVhVkZ2eHc2dXJRWnpBTkczdEU1VFhNVl9rNjJz?oc=5" target="_blank">Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia</a>  <font color="#6f6f6f">Nature</font>

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Leveraging CRISPR gene editing technology to optimize the efficacy, safety and accessibility of CAR T-cell therapy
Naturetech

Leveraging CRISPR gene editing technology to optimize the efficacy, safety and accessibility of CAR T-cell therapy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBSaVNjZFZvT2lBVTYxOVhwbEh0ejExd01LbW5TSmtoTmpnR2ZEOGtfd0tNSEVsRC1nOWxjaVRpZHVXQzJkX01FcnZjNi1ZRS1FVjQ0bW1SLVpuUVBrQUFF?oc=5" target="_blank">Leveraging CRISPR gene editing technology to optimize the efficacy, safety and accessibility of CAR T-cell therapy</a>  <font color="#6f6f6f">Nature</font>

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Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets
Natureworld

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE12LXpvWHJpTFlmOXlkU2NNT1BmWUF2aDJJQllwTXlOY0l2NFRCbVFHRGVwQWdjMGd3Vm90eTliYTVNc21KT1B5MnFPTEpJRUtJTmp0dGdMVlFvZnNxWnFn?oc=5" target="_blank">Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets</a>  <font color="#6f6f6f">Nature</font>

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Leveraging a phased pangenome for haplotype design of hybrid potato
Naturegeneral

Leveraging a phased pangenome for haplotype design of hybrid potato

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE84ck9mcXI0MXNHNl9fVlZicWtNdTdLVG1SZWxRR0xwa2pzNld3anVTa0pSbG9WWUF4dUo5MXBqb21Kci1EZTVqTGltMjJlZVZTcG5QVVZDR2UtUWtzbHJR?oc=5" target="_blank">Leveraging a phased pangenome for haplotype design of hybrid potato</a>  <font color="#6f6f6f">Nature</font>

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Leveraging cell-type specificity and similarity improves single-cell eQTL fine-mapping
Naturegeneral

Leveraging cell-type specificity and similarity improves single-cell eQTL fine-mapping

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBycGNIa3BweGFiaFd6MElsN0dtX2hPQnpXYWMyWF8waWxxajNxTllrQXRGZHRTajRiSTJEWWY1YkkySXN1R3c2R09BX2QzZmN6V2dDS3NXRk9CNXRCVnkw?oc=5" target="_blank">Leveraging cell-type specificity and similarity improves single-cell eQTL fine-mapping</a>  <font color="#6f6f6f">Nature</font>

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Leveraging pleiotropy for the improved treatment of psychiatric disorders | Molecular Psychiatry
Naturegeneral

Leveraging pleiotropy for the improved treatment of psychiatric disorders | Molecular Psychiatry

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE96dHk4UjVFNFNVVUdNS3ZGbDAyeTNhblloYzduRnFGdjB5SF9kT1FyRGdwYXFZekJqMHpYeTV1YktTT09SOEd1VjdSMGxFQzRmTHJ0YmJYcmcyU2c3WEl3?oc=5" target="_blank">Leveraging pleiotropy for the improved treatment of psychiatric disorders | Molecular Psychiatry</a>  <font color="#6f6f6f">Nature</font>

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Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
Naturemarkets

Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9YYkVkTHdweUpxNjBkRUU2a3JfTXJnaE9SVmhnWUsyM3FhTXV3QkRmQWVlMzRPME0xT25pUGh3bDVDTFJHSFNHV2k4VV8wX3U5SWh2X0I3eC1nQWJzNlU4?oc=5" target="_blank">Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets</a>  <font color="#6f6f6f">Nature</font>

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Rare variant effect estimation and polygenic risk prediction
Naturegeneral

Rare variant effect estimation and polygenic risk prediction

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8xSjVpdzdfLXlld3BNT2JjM0pFZ0ZSZXQxYlFxOV83SFdaU3lEc1pqdGJGeTZUUEZYUTIxaURnVHYySFFWMldtWDQ5RlF1MGVMZmFkMTlsNDdxY1pHRHVF?oc=5" target="_blank">Rare variant effect estimation and polygenic risk prediction</a>  <font color="#6f6f6f">Nature</font>

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Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types
Naturetech

Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBMd1h4WTlTTXJJaUtzOGZybHpUWXlyc09QNW5majJNRW96UzdWUDJNNGhjWE9iSzBXaWtvUEhKalBBNXVwY0dpRXNPWHFlNGRQbUhQU2EzTGlaVlhfQV9J?oc=5" target="_blank">Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types</a>  <font color="#6f6f6f">Nature</font>

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AI agent improves accuracy of gene set analysis by leveraging expert-curated databases
Phys.orgtech

AI agent improves accuracy of gene set analysis by leveraging expert-curated databases

<a href="https://news.google.com/rss/articles/CBMidEFVX3lxTE44VW9CWjdDLVFYMVdsU05YMDg3Mi1pUTViZjdPSFBHUkVhaTF4OTBkOXdyMlVfV0IxRWFaUTFET2d6RjhGX0RMSkpYanFNTGVDWWxVb0tuQWhPY1g0YkRQMVY0WEk5T09BVW91cmlQMklFdFZI?oc=5" target="_blank">AI agent improves accuracy of gene set analysis by leveraging expert-curated databases</a>  <font color="#6f6f6f">Phys.org</font>

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Exploiting pleiotropy to enhance variant discovery with functional false discovery rates
Natureworld

Exploiting pleiotropy to enhance variant discovery with functional false discovery rates

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0zaGdoVWdrOHR2c3luYXB4RUljWHJKb1VqNndzODlSQjBfYVdKQks3WGItbFVrM2JiT0ZQUVNGUnNIMkVFaTlZNk1PMVkyT0N2UUR5NzdFYjl2Q2NYdjBr?oc=5" target="_blank">Exploiting pleiotropy to enhance variant discovery with functional false discovery rates</a>  <font color="#6f6f6f">Nature</font>

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Leveraging genomics to understand the broader role of fungal small secreted proteins in niche colonization and nutrition
Natureworld

Leveraging genomics to understand the broader role of fungal small secreted proteins in niche colonization and nutrition

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE16ejY5T0U5NVFhYXVobHBBSm12bGZublJ6cmdQX0RpUWZ6a2llQ2poNTQxZ2tiVjdTcERrb25BbnFGVE51T3VEWGs3NDR1MHk5Q04taGpHNGhiQjRXNmRz?oc=5" target="_blank">Leveraging genomics to understand the broader role of fungal small secreted proteins in niche colonization and nutrition</a>  <font color="#6f6f6f">Nature</font>

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Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program
Naturetech

Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9jOGd2NWh0UzVsLVlwMTVmS182aWpEZ3FpUFhIelhuQWs5dzl6eDVCUFJ5VnZvWFVRQjJuWTBHQ2xxOTY4YmJKb0VZSl96QnlBcy1mWkt4M2RGMWsxcjNz?oc=5" target="_blank">Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program</a>  <font color="#6f6f6f">Nature</font>

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OTTERS: a powerful TWAS framework leveraging summary-level reference data
Naturegeneral

OTTERS: a powerful TWAS framework leveraging summary-level reference data

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1QX3VydHV3SmdWWkpFRlV2YlRSUGNpeVBBQXg0MEhEaG4tUWEyaXhXX05vY0lWTnA0dGdqZnVEUFgweDJMYkpfbG1ma2U5ZlBjRVhDWlRQQzROWV9wRVpR?oc=5" target="_blank">OTTERS: a powerful TWAS framework leveraging summary-level reference data</a>  <font color="#6f6f6f">Nature</font>

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A foundational large language model for edible plant genomes - Communications Biology
Natureworld

A foundational large language model for edible plant genomes - Communications Biology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ONkpEYUt1dk1IVVl0SFRISFdfRjVrUld3RklWUEltVDlxMzBXbTZHYVdvb1Bab2E4Q2hkTHJGMFJIOUdNX1pseDkzYVZpMlhURmpjdXFRV1psX2hwQ0NF?oc=5" target="_blank">A foundational large language model for edible plant genomes - Communications Biology</a>  <font color="#6f6f6f">Nature</font>

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Implicating candidate genes at GWAS signals by leveraging topologically associating domains
Naturetech

Implicating candidate genes at GWAS signals by leveraging topologically associating domains

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTFBZcGJDalZZMlUwRGJ5eU5CMjZDZGVwRGx6dWpKLUlIRmNJUlByX2l4WjJ2ejNsRTdIVU52ZHB4QjlyZ21nVVJEc0dpbWRLX1BmSndGT0FB?oc=5" target="_blank">Implicating candidate genes at GWAS signals by leveraging topologically associating domains</a>  <font color="#6f6f6f">Nature</font>

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Leveraging data-driven self-consistency for high-fidelity gene expression recovery
Naturegeneral

Leveraging data-driven self-consistency for high-fidelity gene expression recovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAyWHdmRFVseFNhV2JoRG5RTE13ZGdsNlJWcEMyM2RmOGtXMDI5VGprNEp0cjZkQjZ6VkkxbjlUR0JkWXNMTmtvM0JHV1hfeDRTMXRhdncxXzZsV2xFSXJr?oc=5" target="_blank">Leveraging data-driven self-consistency for high-fidelity gene expression recovery</a>  <font color="#6f6f6f">Nature</font>

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Using Genomics to Develop Personalized Cardiovascular Treatments
American Heart Association Journalsgeneral

Using Genomics to Develop Personalized Cardiovascular Treatments

<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxPNjRqel93MnZwUFNiN2s4N0paQmJKUXJ2eXBOM3NuWkQ1WjlDTXpxOHBpTDVSVXhYYmhyTGIzUkp3eUtlQW82dEtXWElvRUpOR1RJVVFkWl9McnprVU5DaGItZXVrVnpPaXZXQV9JaGxHWXZDQ1FBVWFmTGc4eUhhYmdtZ0l4NGVPMUxPeUIxazVSTWs?oc=5" target="_blank">Using Genomics to Develop Personalized Cardiovascular Treatments</a>  <font color="#6f6f6f">American Heart Association Journals</font>

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Scientists Leverage Genomics to Save Endangered Frogs from a Deadly Fungus
The Scientistworld

Scientists Leverage Genomics to Save Endangered Frogs from a Deadly Fungus

<a href="https://news.google.com/rss/articles/CBMirwFBVV95cUxOdjFhVHlCaDRFSGRPNUphWTJPOUszX2l0V1FMa0Iwd0llM19aZS1ka3FxODJYUHhkNk9Tc1FUSmE0VW00ZkNuajlLUDFBMDN6R3ZaZXlUb19rQkZrOERRQ0h5ZFZ4dTgyam1vSklEbTM1M2VVUVd3Wk95S1A4MzN6aVoxZ21YMnI1VVpVd3o1clZmcGFtbEFHTDhSbWVrQkpKWVFVemd0TnRDTlBiZFRB?oc=5" target="_blank">Scientists Leverage Genomics to Save Endangered Frogs from a Deadly Fungus</a>  <font color="#6f6f6f">The Scientist</font>

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