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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Inhibition of demethylase" (30 stories)

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Inhibition of demethylase by IOX1 modulates chromatin accessibility to enhance NSCLC radiation sensitivity through attenuated PIF1
Lead StoryNaturegeneral
Dec 12, 2023

Inhibition of demethylase by IOX1 modulates chromatin accessibility to enhance NSCLC radiation sensitivity through attenuated PIF1

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE91OFJiU0VxMnhzZkxJTUVKaHN1VDB3WndGaHNtWDhYdmxUcFdWYXZYLWxyVld5TXoteU5nOHBVbGxzdlJqYnlHZF9wUXVGcTJQZnNWaXd0WFc2RkZURTM0?oc=5" target="_blank">Inhibition of demethylase by IOX1 modulates chromatin accessibility to enhance NSCLC radiation sensitivity through attenuated PIF1</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Inhibition of demethylase"

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29 stories displayed
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms
Rockefeller University Presstech

Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

<a href="https://news.google.com/rss/articles/CBMiqAFBVV95cUxON0N2LVFESjR5TkRRRlJHQVZBVGhLUEtIOEwxODk5V0xIY1FsYjJLMFJzbUZxVDRqWk43cHdpZDBtNnRoMGNVNk9DeUw5WFJlOG12U2hXMDA1LXg2TlVtLVhLOWxVMWJSZThrazQwN3NkU2Z2bU1YZDZsT2pqRkpPY1B3UVhsMTVYTnhHQ3psdDR5cHRaVzdncy1xRUlyV2tQN2NBZU5wdnA?oc=5" target="_blank">Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms</a>  <font color="#6f6f6f">Rockefeller University Press</font>

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Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers
Frontiersgeneral

Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxOajhpR0F1U25aYnRmS1d0OEYya3oza1ZvYW81Z1NaTUVoUE1XQlVkQUVtSklHZU1LQnZSQktYQmZwVjl4OF9tdmpacXhkMHN1NEd2eEd6V1VLSmgxNUhkUjhlRHRtRHJBLUZFWmZJdjBIbk00TXN4SnZWQ1lIQXhhcEpvUHRkcmJmUEZMVWpB?oc=5" target="_blank">Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers</a>  <font color="#6f6f6f">Frontiers</font>

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Discovery of natural apigenin analogues as lysine-specific demethylase 1 inhibitors against tumoral testicular germ cells
Naturetech

Discovery of natural apigenin analogues as lysine-specific demethylase 1 inhibitors against tumoral testicular germ cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5oblF0QVowMGV0QkRJOE9xeWF6LW95SFJlWWJxSTVIWDZrZFFJQng3LWdhbVdUdGhBOURKOUhCNzlnLVZnRkRFRlBaNnpLc0szdEtHZTFMaEhLTFE2eXZV?oc=5" target="_blank">Discovery of natural apigenin analogues as lysine-specific demethylase 1 inhibitors against tumoral testicular germ cells</a>  <font color="#6f6f6f">Nature</font>

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Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma
Naturegeneral

Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1TMnBIVC1rQ3RyQnYwSmxIdGRsZERGcXRhSi1TeTNUOUhPQzVidUZ1a0sxdkNaM3dHOGttWWtPTjFlLXYtYVd2TnkzSjdjdkxYaGhSRUNGV1RTTTJLb2tv?oc=5" target="_blank">Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma</a>  <font color="#6f6f6f">Nature</font>

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Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma
Natureworld

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5iM2ZTSE1CRjVqTVlhZEpla01ESnBPd3JETlV0RHBBXzU5dzBhVzR1MEo1ampXZ3lYem9hcWFxcFU3NnNGZndmN2tHcWtVX2VtakEzZ1l6Ym9vLUlWOGp3?oc=5" target="_blank">Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma</a>  <font color="#6f6f6f">Nature</font>

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Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance
Natureworld

Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1oSjJTMng2TG5JdWlqTTl1dk1zQmpyRG5KVEtoMHhGYzczTDNZdFF4QmkzNXBZMDFoV0RHWDg2R0hoZGdDYTFVLXNzTzdPMV9majIxRS1qa2hMRTRTNHFr?oc=5" target="_blank">Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance</a>  <font color="#6f6f6f">Nature</font>

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Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth
Naturegeneral

Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5yY2tXSTVNRDQ0YUVDeW5NTW1lcGlTLWNYTkNuOXpiT1hFelJyVmdwZDhOekhNdG1iQ0FWOVBzX0VxOGZ4WFdTNmxsS19HNXI2cGh2amxaU2dxYllkeHNr?oc=5" target="_blank">Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth</a>  <font color="#6f6f6f">Nature</font>

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Histone demethylase inhibitor KDM5-C70 regulates metabolomic and lipidomic programming during an astrocyte differentiation of rat neural stem cell
Naturegeneral

Histone demethylase inhibitor KDM5-C70 regulates metabolomic and lipidomic programming during an astrocyte differentiation of rat neural stem cell

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ESFhDTXNFcUJuTzZWNF8xUEFRUmx5TzBDbGpEa0VCS0NISzBralpMX1hQelZOYXUwRWVTbE13R2xIZnBwVTd6TV81VHpqX2xTdWpfdndFSDlOTWxYbE5Z?oc=5" target="_blank">Histone demethylase inhibitor KDM5-C70 regulates metabolomic and lipidomic programming during an astrocyte differentiation of rat neural stem cell</a>  <font color="#6f6f6f">Nature</font>

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Abacavir enhances the efficacy of doxorubicin via inhibition of histone demethylase KDM5B in breast cancer
Naturegeneral

Abacavir enhances the efficacy of doxorubicin via inhibition of histone demethylase KDM5B in breast cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1Da3dQbDlaNHhUeVdSZTFUVUF0Q0JtTGV6VVdER3Z6UnpRZDdISE5LTEVQWTFYckNWd3B2RDZxTzZUUm1uU1dSOGF1azV1SXdHZFlDM2daRXNxbW4tQTB3?oc=5" target="_blank">Abacavir enhances the efficacy of doxorubicin via inhibition of histone demethylase KDM5B in breast cancer</a>  <font color="#6f6f6f">Nature</font>

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Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease
Naturegeneral

Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE0tYUFJY1pvc3BIdzZkMVJ6Vm9YSGFfMWhMd2ZzTDZUTG5uVkhVTGZYTHkxdFhQRmVuQ3lFNkxNTTVwdGZWbE0xSl90cGl1T1BIRFZsbU9GdTlPSVU5N0ZJ?oc=5" target="_blank">Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease</a>  <font color="#6f6f6f">Nature</font>

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Jumonji histone demethylases are therapeutic targets in small cell lung cancer
Natureworld

Jumonji histone demethylases are therapeutic targets in small cell lung cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5sMEN0R2thTnlodFNiSTlvb3ZIUHgwX1NkOVFxU3ROcG9jUmtyM3FSRjZUNnRUNFA0NTI3b19JRUVDVlU4aUt0cWhmOGZJcmlpa2xUdC1WcVFUa2U0M00w?oc=5" target="_blank">Jumonji histone demethylases are therapeutic targets in small cell lung cancer</a>  <font color="#6f6f6f">Nature</font>

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LSD1: more than demethylation of histone lysine residues
Naturegeneral

LSD1: more than demethylation of histone lysine residues

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE10SXl1cnRmQUdkc3ZaeWJuczF0Wk1wdDJCWWdfVlZoaE9YakVyWG5QQTZNeWRlbFBRYUhtamlEU0M4QS11QVZfWHJuT2ZOTXplTlBTdHIxY3gzWGZTNkhn?oc=5" target="_blank">LSD1: more than demethylation of histone lysine residues</a>  <font color="#6f6f6f">Nature</font>

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Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition
Naturegeneral

Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE83V3preUkyVjhQME9aSlNadlV3NXhGOGZJeXpKMVZzVkozVlE5ZWMtNkNHZC1LaTNLWWQ3ZEt6YmpLRDcxbHVaWm5rUWc0OHBBR2p1NTd5ZzFkQURsbUJB?oc=5" target="_blank">Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition</a>  <font color="#6f6f6f">Nature</font>

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Histone demethylase KDM4D inhibition suppresses renal cancer progression and angiogenesis through JAG1 signaling | Cell Death Discovery
Naturegeneral

Histone demethylase KDM4D inhibition suppresses renal cancer progression and angiogenesis through JAG1 signaling | Cell Death Discovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4zVHBqSVkwUjd0bExSMkhoTTJFWEdXT0k0TDBRRHhBLVVKLXJtNlIxbGtlM19YcVBNOVNtZ1Ftb2NDbGttc0c1R1dXWnVYcTgtLVRPR3dNMkNjU2RKYk9j?oc=5" target="_blank">Histone demethylase KDM4D inhibition suppresses renal cancer progression and angiogenesis through JAG1 signaling | Cell Death Discovery</a>  <font color="#6f6f6f">Nature</font>

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Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
Naturegeneral

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTFA0anlMUzVXMVBNWTN2MXVBVTNhcjQ0UmN6TFFrUnJVSVI3X1MtMkZTcExwWlRycmhhTkE1NTBwWFhmZjhZTDBrV3lfY2N4Ul9LOWZsdndB?oc=5" target="_blank">Highly selective inhibition of histone demethylases by de novo macrocyclic peptides</a>  <font color="#6f6f6f">Nature</font>

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Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch
Naturegeneral

Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTFBrd1pQNHNfckFUSUQ1RGJUUElpS1M4SUM2dFJZVTJkQ1Jodk1xeUhGVXlBYzdiUjh6aTdKZVdoMFJfdzFqSkY2SUtsSDg1dEp6aEdn?oc=5" target="_blank">Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch</a>  <font color="#6f6f6f">Nature</font>

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Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activity
Naturegeneral

Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1IRWNzZmdVcWduVERybUNNSkdxTkJqTlJEcEJ6YzJEdVlYLVdfN1UzRmdudEQ5ZEEyRUJablhBN1FKZng0eWVUQi1Xa19Qb1R2aVp3dG9XbHI1VE1DUmdF?oc=5" target="_blank">Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activity</a>  <font color="#6f6f6f">Nature</font>

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Lysine-specific demethylase 1 inhibition enhances autophagy and attenuates early-stage post-spinal cord injury apoptosis
Naturegeneral

Lysine-specific demethylase 1 inhibition enhances autophagy and attenuates early-stage post-spinal cord injury apoptosis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1oZUdna2lENDRGLUdsd1QtR3Z3azVzTnpBaldYalM1b2VpU1U0bXVwcDZDTnRqQWRTV05GRW56RzlSeWhMNXFQVzhCcVVCRDQ0TEtCdVVsSFVFZlZIX04w?oc=5" target="_blank">Lysine-specific demethylase 1 inhibition enhances autophagy and attenuates early-stage post-spinal cord injury apoptosis</a>  <font color="#6f6f6f">Nature</font>

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JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway
Naturegeneral

JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBEWk44aWtuQnFLcmM1cVN2bThzM3Fjd3RpOFJTZkxucTBwbzMzci0zM3ZoSWJsSm9TMm5JdVlNakJUZlg5ZVhtLVdrV2dpQnlVeDNJY21hR3JRV0RKNW1z?oc=5" target="_blank">JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway</a>  <font color="#6f6f6f">Nature</font>

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Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia
Frontiersgeneral

Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia

<a href="https://news.google.com/rss/articles/CBMiiwFBVV95cUxOcVdLa2w2RlNMNVdYTkdUSzY4VFBKblVBa205MGRQTXhYeHJnZGpabFVDTnJLRUh6cHBYTHlQSlF3cmJKS2wySzczT1czNl9iVXN2YnVQM2pHMDhlaENCWTc0c2JkZ19FMFFWMklDMFFxcHQ4UFdiMDNpVUU5M2xKNVNDekJJamJjcjRF?oc=5" target="_blank">Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia</a>  <font color="#6f6f6f">Frontiers</font>

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Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study
Naturegeneral

Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5NNFZza29yRVVPWGxURDlhel9TTS0tN0hwN0hxeEQxdFJfSkpfYnRfWjBMUE4wc3BxRGlpWTlkdjlkWjdiWE5zaU5jbmNyM2hYSW0wSG1rZ0EtSEVCUnVR?oc=5" target="_blank">Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study</a>  <font color="#6f6f6f">Nature</font>

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Histone demethylases in the regulation of immunity and inflammation - Cell Death Discovery
Natureworld

Histone demethylases in the regulation of immunity and inflammation - Cell Death Discovery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1zb3U0czVWbFBVRHFzYm1JbWQzX2MzRzJ0RnQxcVJCSHJ3RV9uYllHZi1XaWpyVGJ4T1Jzdm9SQ2Eycms0ZzAtM3kwQ3RqU2pObXJ1ZnZDNUM1cENMdXpn?oc=5" target="_blank">Histone demethylases in the regulation of immunity and inflammation - Cell Death Discovery</a>  <font color="#6f6f6f">Nature</font>

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Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
Naturegeneral

Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5BLWE1alduaWtaU09SYnpvZHZ5RkFQeFhCLUZqS3JWRDVTYWVFbVVqQWNjS2lGN2NJTzg0LU5MVVVQemIwV2NGN1VGZDlrOGloaFlnV0d4V1V4ZVc1RFZV?oc=5" target="_blank">Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis</a>  <font color="#6f6f6f">Nature</font>

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The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression
Frontiersgeneral

The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression

<a href="https://news.google.com/rss/articles/CBMiqwFBVV95cUxQcDJiVmZ4dGltU0xuRUNrUUVmcTNoSkNWZV9LNm03UDAwT3dzeXpyRkF0dTF4LVN0QjJVUVZiTDhqRVhkOWl3QnJWVjFid0tEdDJreEEwdlQ3SG80aFBQSjdLQ2FlQ1lIQ09PRjNOT21WVHI4dEFDNWc5a1dnZmhUOE9YUUVjSWNxZnhXbDdMSTdQU0p2SmZPeHNYYXN2YzJXOFFKd1hIR2p0UlE?oc=5" target="_blank">The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression</a>  <font color="#6f6f6f">Frontiers</font>

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Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome
Naturegeneral

Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE40UUZZMlZIT1lNcWQyX3dITmJXYlNMMmtTbHdITHJ5UmRLcHNJSUUtUm1wTmQ2d0NkTUlQTjY2VG9yQlA5YWN0T2FPdG01a2tDVlJ0QllwdV8xd3FvSVFV?oc=5" target="_blank">Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome</a>  <font color="#6f6f6f">Nature</font>

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Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair
Naturetech

Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5QZ09FekpsVXZDeXJCOGFyWUpabnpSQzFHekxXcnA1U2k0b1J6SmZYd2pQbURQWktPd0pFTXk0QzEtdTlad3p2RTgtZ19IRHltUVVRSXVyb0kwNzJuVGNv?oc=5" target="_blank">Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair</a>  <font color="#6f6f6f">Nature</font>

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Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma
Science | AAASgeneral

Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma

<a href="https://news.google.com/rss/articles/CBMiZ0FVX3lxTE9MOE41XzhHMUd2VjlteXVadkptQzExVWdnUl84X1VLdzl0Tnl5a2dzd0l2NUQ3bmszcWpOaUFpUHoyZE9ZWDc3dzk2TmppNjcxbHZFWXZxdVNOeTIwajhGZFA3TXF3bTQ?oc=5" target="_blank">Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma</a>  <font color="#6f6f6f">Science | AAAS</font>

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Structural analysis of human KDM5B guides histone demethylase inhibitor development
Naturegeneral

Structural analysis of human KDM5B guides histone demethylase inhibitor development

<a href="https://news.google.com/rss/articles/CBMiWEFVX3lxTE1ldUlHV01pdFQzYUhPMDR1cU53alh3enE5VEtuY0xrUmtWX0d3OV9KRnBTdHVHcE9LNG5IUE42eElwV0tLdk94elZrWjRJRmZEWC1NdTRzUjA?oc=5" target="_blank">Structural analysis of human KDM5B guides histone demethylase inhibitor development</a>  <font color="#6f6f6f">Nature</font>

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Targeting lysine demethylase 5 (KDM5) in mantle cell lymphoma - Blood Cancer Journal
Naturegeneral

Targeting lysine demethylase 5 (KDM5) in mantle cell lymphoma - Blood Cancer Journal

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5VR2ZCOThKSDhSODVqM0hVVTAtaEdiYWNpV041QU9JZnJJOHN4bXEzbEE3OXl5VE5rTFg2V0RUTmxMaFpENHhnSDhsT0pUdjA3aS10Q3hXbVlvMlNQRDU0?oc=5" target="_blank">Targeting lysine demethylase 5 (KDM5) in mantle cell lymphoma - Blood Cancer Journal</a>  <font color="#6f6f6f">Nature</font>

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"Inhibition of demethylase" — Live Google News Trends & Headlines