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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Inhibition of EZH2 induce" (30 stories)

Top Headline Story

EZH2 inhibition via GSK-126 mitigates EndMT and atherosclerosis in diabetes: A translational epigenetic approach
Lead StoryScience | AAASgeneral
Jun 22

EZH2 inhibition via GSK-126 mitigates EndMT and atherosclerosis in diabetes: A translational epigenetic approach

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA1UmwtUkdJd21pdUpKcW91V205Y0piVWF0UFJDRWVTV0l3LXhzYU9LeUZNeGd5WXJxcmNGTUV1aHVZVHVvVDBjTkdGRDVsODRFUkp1QUpiaUV2bUNxT1ZZ?oc=5" target="_blank">EZH2 inhibition via GSK-126 mitigates EndMT and atherosclerosis in diabetes: A translational epigenetic approach</a>  <font color="#6f6f6f">Science | AAAS</font>

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Search Results for "Inhibition of EZH2 induce"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion
Naturegeneral

RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBoUUdLRTdPb0otMHk4Z0YtWFFobVBLWDQyMVlLM0Q3cktacmlOcEh5cmdlUEtWZ2FLb090LXBPYkM3eU1QVl90cThycWJ4UHpoQnVwbzdvRWFXdlRhT1hV?oc=5" target="_blank">RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion</a>  <font color="#6f6f6f">Nature</font>

Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells
PNASgeneral

Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE9abFVDQ0ptYTd0ZGk2S09SeThhclg0NVpQdXBxWnRacXRpcDF1U1VxaTQ3UHphT3FZRWxuRndPM0s5Y0lwQVdoWTZhTmlaT3VtTFZMdWdOZjBVUjRR?oc=5" target="_blank">Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells</a>  <font color="#6f6f6f">PNAS</font>

Inhibition of EZH2 alleviates SAHA-induced senescence-associated secretion phenotype in small cell lung cancer cells
Natureworld

Inhibition of EZH2 alleviates SAHA-induced senescence-associated secretion phenotype in small cell lung cancer cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE13a2FnVXNCd3BreXZ5Rkc3R3ZUa2tUakpkeFpUSDBhMjNSdTJIbV9tZ2M1ZF9VUUZnWi1DNzRfc1Nzclo2MFBjUzR4V1p3bU1YNTIyU2NhNDBROWRmRS13?oc=5" target="_blank">Inhibition of EZH2 alleviates SAHA-induced senescence-associated secretion phenotype in small cell lung cancer cells</a>  <font color="#6f6f6f">Nature</font>

Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma
Science | AAASworld

Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9mRXF3MEs5QlVVYWhjSW11TGxZRjBVcTM1bVo0NnV2VXlZdTM3aVU4VV9QcWhncXF2ZnBoWVc1cGg1TlQ3X1Q5SHo3R0hPY29KRkQxOWUwR2QzYUxYb19v?oc=5" target="_blank">Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma</a>  <font color="#6f6f6f">Science | AAAS</font>

Combining EZH2 inhibition with senescence induction helps immune cells fight pancreatic cancer
Natureworld

Combining EZH2 inhibition with senescence induction helps immune cells fight pancreatic cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBvb293UzRqTjg4T2w0UDhSOVUtUm5CUWo2Q3BtRkg3LWNFWG1MblRFamFRdmhOTHVuVWN0UDgySVNocms5SDBNaTZYNU1sNlc4TTdZWi1GSkE0U2tGamhZ?oc=5" target="_blank">Combining EZH2 inhibition with senescence induction helps immune cells fight pancreatic cancer</a>  <font color="#6f6f6f">Nature</font>

Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein
Naturegeneral

Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE16SVZDR3M1Qzh4QmMyTW5XOG5odEJfT0NLaGQzdEZpYTc0U0cwMFFVVmRqa0RBT0NmQmVKVVZMY2w0aEtFSmFNSVhnOGlLY0EycnBHOUR2bmZNcFlvOGNJ?oc=5" target="_blank">Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein</a>  <font color="#6f6f6f">Nature</font>

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution
Naturegeneral

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE05WjhURE80WjJkbnk1M0xWSUlPUEtOQkJfdXJsMVZHMFk3MFJZN1RFNEcxVHNSLTBBRXJIeGMtVDJ6M3kzaGtIelp5ZXJSTnNkMFJBQ3N1cWZXbkFoR1Jr?oc=5" target="_blank">AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution</a>  <font color="#6f6f6f">Nature</font>

Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis
Naturegeneral

Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9qcllwbExjMTVpRnd1TEJrLVBhTTNscFE2YmJtODE4VVZsT29KNGJEMWVFT0J2UFlVRVh0ZWVyTEZiTndrTUNDSzlvS2NvUkR5ZVdkamxpc3FHN2V1N2hz?oc=5" target="_blank">Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis</a>  <font color="#6f6f6f">Nature</font>

Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer
Naturegeneral

Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE9FM1FwYV9mVGpWdzFHS2tRemJ5WVVmR0doc0dBM0k5Yk5wNkJ4eV8wUkRRdF9Ba1dIdlk0bXU3Rm5mWnVZVG1LdFBSd0p2MGtYdzJJ?oc=5" target="_blank">Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer</a>  <font color="#6f6f6f">Nature</font>

Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer
Naturegeneral

Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTFBPaUs4el9TWlYzUnJrUm5OQVNpSXFOOVA1UWpaQUdrUFZVam9KdlRldDFBcE1qcVFEaWhmVzNSQ1JPVTRnUzZuSmw2cC1mcXRmRzd4SXRNVG5qNXhmY1E?oc=5" target="_blank">Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer</a>  <font color="#6f6f6f">Nature</font>

RETRACTED ARTICLE: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer
Naturegeneral

RETRACTED ARTICLE: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9IRF9DV2ZVWkZMXzB6YkFpQUlhZ1I0SFVaVGZpWlRtRTVmME5HVVJSVGZNbTZvVEhBbmtCTEZlVkJLX0hQSElmalloQndJbVFRVnVZQktsV0lCUTNVNkFz?oc=5" target="_blank">RETRACTED ARTICLE: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer</a>  <font color="#6f6f6f">Nature</font>

Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma
Naturetech

Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8wVFMzRWJpcDFLelM2R3FCeGJ3bWV0QkhhdzN4MERzNFJ5ZVR4ZU1mMnJrdFNSSGMzNkZxQzFIVURWcnBKZzRZTEdYcFZHMXMzdzdEYWh1MFJuTGljVUo4?oc=5" target="_blank">Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma</a>  <font color="#6f6f6f">Nature</font>

EZH2 serves as a viable therapeutic target for myeloma-induced osteolytic bone destruction
Naturegeneral

EZH2 serves as a viable therapeutic target for myeloma-induced osteolytic bone destruction

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE05UFQzbTBYWjE5WHBNbDZNZnQ2UFprR0o5Y1VCcnBVUzgxaE82ZlptNHdERmtWNzFEMDdSRTZmSGpGXzhscnAyblR1bGp5bldXZEI3UHFEN0x5QVh5eVpB?oc=5" target="_blank">EZH2 serves as a viable therapeutic target for myeloma-induced osteolytic bone destruction</a>  <font color="#6f6f6f">Nature</font>

Activation of FXR and inhibition of EZH2 synergistically inhibit colorectal cancer through cooperatively accelerating FXR nuclear location and upregulating CDX2 expression
Naturegeneral

Activation of FXR and inhibition of EZH2 synergistically inhibit colorectal cancer through cooperatively accelerating FXR nuclear location and upregulating CDX2 expression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5UTWpiZG9RTEhINmIxR0xzSGFZTm5ORmNpN2JCbE5uTy1tb1pVSXdqdWdxUXdUa1NYU0xDaVh2UVlmcHFCZnctMmRWUy1aYUVmeXAyTmp6blZGSF93Y0Zj?oc=5" target="_blank">Activation of FXR and inhibition of EZH2 synergistically inhibit colorectal cancer through cooperatively accelerating FXR nuclear location and upregulating CDX2 expression</a>  <font color="#6f6f6f">Nature</font>

EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells
Naturegeneral

EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4taDRDQ0IyVlJUM2lQZjVnczVIUE44S3dDeHdwdGZuMFQtdTJhMjRrZ1RZeTFQc21rT0hWR3lCbHN2aTM0emF4T24zUlVZWXFYcFRQUmhuY3JlNnNNZnY0?oc=5" target="_blank">EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells</a>  <font color="#6f6f6f">Nature</font>

EZH2 inhibition sensitizes retinoic acid-driven senescence in synovial sarcoma | Cell Death & Disease
Naturegeneral

EZH2 inhibition sensitizes retinoic acid-driven senescence in synovial sarcoma | Cell Death & Disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE94QVpmQmpsLV9TWW5FSjNRYTBVSFI5d0NxWERsMDlRVTFtdmhSMklqbmhLbV9xNmljU0VXVWdSRUJDaHRQZG1ONGNfRGRsZjJFTExkYktnYTd1ajg0MzdV?oc=5" target="_blank">EZH2 inhibition sensitizes retinoic acid-driven senescence in synovial sarcoma | Cell Death & Disease</a>  <font color="#6f6f6f">Nature</font>

Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer
Naturegeneral

Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE14dkZ5ZTc2dG1oTUNGUGdiUlJadGpzNVprTUJfbnJsb2JaM1dTRUtfdmFjeGZLSmxQRFpXcVRFalVFYk9lMVczWFZka3VfQ3M5VG4zaVNQRnJrWEZSRk8w?oc=5" target="_blank">Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer</a>  <font color="#6f6f6f">Nature</font>

Enzyme-independent role of EZH2 in regulating cell cycle progression via the SKP2-KIP/CIP pathway
Naturegeneral

Enzyme-independent role of EZH2 in regulating cell cycle progression via the SKP2-KIP/CIP pathway

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE81YUVaTWhrbkNVR21pbVRrdWxaLWtwRXRDTFo4Y2gtdWFfNkNfVTFOUmZvUnlYVWg5eVE0ZGY0Vm9LcV8xODlPSUg5QVVoOTRVSDlQb3ZjWWFhbERnTnNR?oc=5" target="_blank">Enzyme-independent role of EZH2 in regulating cell cycle progression via the SKP2-KIP/CIP pathway</a>  <font color="#6f6f6f">Nature</font>

EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition
Naturegeneral

EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9ydUZxVmJFM096SHk2OUY2eEhzMzl4c0s3MVFEb3dvZFRjbVdsTVFJV2JMZnVCdWxPalhYYzBFY241MVRxTUhKeGtBbnM0MFZQYWFqY0FudV9JbGFpZDFZ?oc=5" target="_blank">EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition</a>  <font color="#6f6f6f">Nature</font>

p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis
Naturegeneral

p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5Cc0k3cWJnUVlJZjFfelJ3enRSYkpzaGJETldLZEo5U2ZEYXNZTHdJdHpWMzRuOWpCUW5XSnRGcUFBSDRGVVM1eFFILUFNS3ZOQ2VRRjY0cUNEbFlpTHRN?oc=5" target="_blank">p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis</a>  <font color="#6f6f6f">Nature</font>

Combining EZH2 and HDAC inhibitors to target castration-resistant prostate cancers
PLOSgeneral

Combining EZH2 and HDAC inhibitors to target castration-resistant prostate cancers

<a href="https://news.google.com/rss/articles/CBMigwFBVV95cUxOQWpsSVdCX1NhcHNWdzFrSjl2eGFyaVJURkgxZDZvZHNhX1FuV0hJMzJBTzNtNE1KOEYtbmZwMXVYUWZOMDcwZldNaTdaN0s4TmV3X1RjNzZBaG5zSVRuRVktN1dvX29DRXNQcElwTGdDaVJnNzJMVC1ESXZrcDFjWFl6MA?oc=5" target="_blank">Combining EZH2 and HDAC inhibitors to target castration-resistant prostate cancers</a>  <font color="#6f6f6f">PLOS</font>

EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors
Natureworld

EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9zdW50RnJfYkpLNURFTkNyQk1fOGpVTGdmZ0hKVHdMR1FkdW1UWGxGWk1hU3hBd3BYV1FhT0dGbzI1WFFrcjdibVd2UjB3N1FxSXFpeEVUSDZJTXBWdnM4?oc=5" target="_blank">EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors</a>  <font color="#6f6f6f">Nature</font>

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
Natureworld

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5yN1YtSjRYVmF5VTZ0TXZuRzAxZDZuUHBOMXFHNENEUzdlUV9tSVZQU0p6ZzMyLVlVSlg3QWE5Y2xtODEtYU1laHk3aWlTd1BLTGZKM3lqVHdrci1MV2ZN?oc=5" target="_blank">EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma</a>  <font color="#6f6f6f">Nature</font>

EZH2 presents a therapeutic target for neuroendocrine tumors of the small intestine
Naturegeneral

EZH2 presents a therapeutic target for neuroendocrine tumors of the small intestine

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAwY3lST2tEdWp0Q2JTc1pKejZnMlQ5WlRJemZUcWlNUk4zZ0VlM0t1elYzVHE4Qlo3MWVvQzF0WXpSMDZjQkkzLUtROUt1LWRMby1nQ3ZGQ25hVWZYNEJz?oc=5" target="_blank">EZH2 presents a therapeutic target for neuroendocrine tumors of the small intestine</a>  <font color="#6f6f6f">Nature</font>

The inhibition of EZH2 ameliorates osteoarthritis development through the Wnt/β-catenin pathway
Naturegeneral

The inhibition of EZH2 ameliorates osteoarthritis development through the Wnt/β-catenin pathway

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE1zamlZb1g2enA0ci1ZTGhId240ZmNuWXMtc0h0eFdoZlVDU0trZ3ZhVmFTcDk2bGU5bDNSYmFGMXZ5dExtVmpWcEdrM1B1bXE4b0hj?oc=5" target="_blank">The inhibition of EZH2 ameliorates osteoarthritis development through the Wnt/β-catenin pathway</a>  <font color="#6f6f6f">Nature</font>

Combined inhibition of PARP and EZH2 for cancer treatment: Current status, opportunities, and challenges
Frontiersworld

Combined inhibition of PARP and EZH2 for cancer treatment: Current status, opportunities, and challenges

<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxQSkFFMTR0VnFtOU5hZ1hra2ZyQkhqemh2dlJrdXFnTHBGZ25yRFFQbXRzNTZvQWxKa2NGeXkyVDlDdUYxNFVIeWRYdzc4Q1I4MVZmams5VHczTVpmQTR4cE9ZWjhrSzlQM2s0SU5PVWNPY1RfV1FGcS1oSUk1XzUzcHBGNDNfUlRBSWZjeWxBU0kwMjg?oc=5" target="_blank">Combined inhibition of PARP and EZH2 for cancer treatment: Current status, opportunities, and challenges</a>  <font color="#6f6f6f">Frontiers</font>

EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis
Naturetech

EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5GZmY1cUltM1cteTNtSW9FS3FCQzFWX0hrcFBUeGliVUdHVmF6NDczc2xUQm9CVklkTjI2TnYyQXhaSzAxeDhLYnY2VW56Q21iajljSk9ZbFk1TklwYzRz?oc=5" target="_blank">EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis</a>  <font color="#6f6f6f">Nature</font>

Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer
Natureworld

Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE90UTJQb19vQzdCcDA3eHNITFVRLUpWSjJ6THFLM1BDTlRpNW9pMVpEaFhoV240R211d0lfVEdla2ZtSmxRWElET193RmtubTNKYUFhS3ZtNi0yb2pCQWsw?oc=5" target="_blank">Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer</a>  <font color="#6f6f6f">Nature</font>

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways
Naturegeneral

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE02MjdocUNJelQ3T1lUdWVnTC1RSl84S0VoeExMdUxTNWVWcm1lMFBnU3lLRmwwcFY5ZFl4eUZhZkI4LUdscE1sdk85OUZUTHRTbFNtMmtBQ3ZGRkJYeGNz?oc=5" target="_blank">Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways</a>  <font color="#6f6f6f">Nature</font>

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