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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Identification of E3 ligase su" (30 stories)

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Identification of an allosteric site on the E3 ligase adapter cereblon
Lead StoryNaturegeneral
Jan 21

Identification of an allosteric site on the E3 ligase adapter cereblon

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBJZllrQ3M4M0FVaENWa3hrVi04aW9EbTdrVlkzVnlkN09kNmdvS1ZLSWtyT05pbGlwNkNmUjBJU2xFdWFlNEJqaGlyZjRabXZmTHVqSFlybXFBOFMzS3o4?oc=5" target="_blank">Identification of an allosteric site on the E3 ligase adapter cereblon</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Identification of E3 ligase su"

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29 stories displayed
The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction
Natureworld

The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9hLUtBcmdTQVd3WjNma3o1MnRKVzVGNUoxQWJJZGdJVkJxdThRbEg0clFqX3N4VVJaUHVlakpCTTZXV2M2UXB4UC1VUUJHNnl4R0xpaGNiMXA1ZXNyWFhZ?oc=5" target="_blank">The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction</a>  <font color="#6f6f6f">Nature</font>

RNF126 is a peroxisomal fate switch enabling redifferentiation therapy in hepatocellular carcinoma
PNASgeneral

RNF126 is a peroxisomal fate switch enabling redifferentiation therapy in hepatocellular carcinoma

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1pNlE2ZTNpa08xUndheTVxMjV5T0dXRElDUXZ6U0xUTWpGUFdOM3VJOEhkRU4wMWljbm1pSWVubndkOXVKRkE5N2ZMY1haWGdXY3N1WkJMcy0ySG80?oc=5" target="_blank">RNF126 is a peroxisomal fate switch enabling redifferentiation therapy in hepatocellular carcinoma</a>  <font color="#6f6f6f">PNAS</font>

E3 ubiquitin ligases in bone homeostasis: from regulatory mechanisms to skeletal diseases and therapeutic targeting
Frontiersgeneral

E3 ubiquitin ligases in bone homeostasis: from regulatory mechanisms to skeletal diseases and therapeutic targeting

<a href="https://news.google.com/rss/articles/CBMirAFBVV95cUxPN1V0NlZ5TDhVSFU0RXE3SG9KMXIwalo5UTJrWmpyNDdOOVdSU05yRll1OE8xZ1JrRGJiTUY0QXpWdk5iTFNOX0toQVVVVHNiV2pRY1lMRTNtanY2M1VILV8zQUowOE1fdXdXWElkV2ZLLTRoXzdld0V5U3o0eGdYYXRodFBZN2VrbzVZcHRLMnlUUmJ0ZXFVQWE3NXhrVllrRGRWNUZLS0lYX0FQ?oc=5" target="_blank">E3 ubiquitin ligases in bone homeostasis: from regulatory mechanisms to skeletal diseases and therapeutic targeting</a>  <font color="#6f6f6f">Frontiers</font>

SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
Science | AAASgeneral

SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1NN0FzVjYzZm9wQXYyT05LWE43NmthWm5DbEhFRW9TWklvcGpJQmRqNEdRNHE5SWNFZWVPM2lXR1luTXNPOEhwOVVUWDlNcmpOT0x4VXNjQ3NFMXhsSHh3?oc=5" target="_blank">SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome</a>  <font color="#6f6f6f">Science | AAAS</font>

Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy
American Heart Association Journalsgeneral

Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy

<a href="https://news.google.com/rss/articles/CBMibkFVX3lxTE9PNVEyd2FmUm5zdWRyRkZHamhlZXJQME1lMWQyMVZUVUh3OVNfakhnV0VJWUxoQ3QwSmVmSzByNDlnXzZzUmlxT2hGMXhMYnJDOWE1WHpnamZLVlcxazJ3NDFzOUN5b3QyS1lBQnpn?oc=5" target="_blank">Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy</a>  <font color="#6f6f6f">American Heart Association Journals</font>

The vaccinia virus protein, C16, promotes the ubiquitylation and relocalization of the antiviral E3 ubiquitin-ligase, TRIM25
ASM Journalsgeneral

The vaccinia virus protein, C16, promotes the ubiquitylation and relocalization of the antiviral E3 ubiquitin-ligase, TRIM25

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTFBvblJGSEcwVEt0NzdPVHV6ZTY4dkt2N2VvOU45V0gyUWVMRHVIblluV0Z2Q2ZvX0pCSUNnZl9jTzAwRDlGVDN1UVlSTlBSTnFOYnlTNVlXRDZ1ckVhVThBVmZ0NA?oc=5" target="_blank">The vaccinia virus protein, C16, promotes the ubiquitylation and relocalization of the antiviral E3 ubiquitin-ligase, TRIM25</a>  <font color="#6f6f6f">ASM Journals</font>

Identification of MKRN1 as a key modulator of the p53-MDM2 feedback loop | Cell Death & Differentiation
Naturegeneral

Identification of MKRN1 as a key modulator of the p53-MDM2 feedback loop | Cell Death & Differentiation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1WVWRBZFJoMllsRjZWZktzNHdnVC1CN191UGZNUkZxWUFRcWh4Q19XejMyXzk5cEpfbmRYRWU5Ti1sMzE2YTctUHNFZ2hMUGhOZzE2Y3VkcXUwTUNaOEJr?oc=5" target="_blank">Identification of MKRN1 as a key modulator of the p53-MDM2 feedback loop | Cell Death & Differentiation</a>  <font color="#6f6f6f">Nature</font>

DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift
PNASworld

DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE43UUdSb05WMGxRQ3FxZWFBRkZTSE5WbW02QlpEZ3ljQkN5VzRVbEJRSnNBN1FFRTNSWkREcjRFMkpIeTBGS0oxLVh4ZTRmR2NfUFI2Vy1NNXNaLVpP?oc=5" target="_blank">DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift</a>  <font color="#6f6f6f">PNAS</font>

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy
Science | AAASgeneral

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE82YVVwVlFwLWRfLVFwVmRLbW5WaE81c2xJdzV2YmJZOVFjSGV5OERpOEw4RzNYVk5mNHJfRklTZm5HNHFkaUtzaW9DcWVUX1FKb05fYW9QYVlrMERGc2FRMw?oc=5" target="_blank">Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy</a>  <font color="#6f6f6f">Science | AAAS</font>

Ubiquitination in plant nutrient utilization
Frontiersgeneral

Ubiquitination in plant nutrient utilization

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPekxPT2tMNHowbTBpSjQ0YVl4NVFuRGdQQ2R0LTd0aU5tOG9SdmZBNFpYbHRVVVhPS0ppX04zcUtPamJ1MVlHbVAycFIyejZfZ3JqbUdGLWhYallLQ1JyU3RWWkc0dGcxRkRXRlRvNnJ2d0hVdjdISGo5MldzTFkteXRaelVJNG9ROEZJNFBDeGtxQQ?oc=5" target="_blank">Ubiquitination in plant nutrient utilization</a>  <font color="#6f6f6f">Frontiers</font>

Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates
Naturegeneral

Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE52Vnc4ZHRfb2hCcG1YYWlhN1p1NEhMbFRZeGNkeFQweDBUUENCUTFWS3M5bFllcTIySHhwa3BvNWFzQnk3YVp6SWJBeW9IR01YU0J1bmpzVDE3UDNiV0Q0?oc=5" target="_blank">Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates</a>  <font color="#6f6f6f">Nature</font>

RING Zinc Finger Proteins in Plant Abiotic Stress Tolerance
Frontiersgeneral

RING Zinc Finger Proteins in Plant Abiotic Stress Tolerance

<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxOTWdTOW9leVZqckVJejNyVFpudXA2MW80OEJac2JlanYwU3ZuVktQb055cVZZbHRaRTktLS0tdHN5VWRfQ2MydzFFbXV3dUZ3WnFyZmZYaEFsWGNpZWRMZ1dTeW96MGZqeGhTNVVVMUdDRnFST0twQm5xMlNockNGRkd1cXBOVHhGMWVXek14dmRaOTA?oc=5" target="_blank">RING Zinc Finger Proteins in Plant Abiotic Stress Tolerance</a>  <font color="#6f6f6f">Frontiers</font>

Identification of RING E3 pseudoligases in the TRIM protein family
Naturegeneral

Identification of RING E3 pseudoligases in the TRIM protein family

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5GdFlmNVRHMkpqRnBBUktvY2pOQk43Y2VacjJtNnVYVC01TDRGcUhYT0ZHV2hBVWRrNWhXZUI4c1VXejVqSjh0eHVqbEdxZzVoNDFBWUpSQVN0Nm1PbndR?oc=5" target="_blank">Identification of RING E3 pseudoligases in the TRIM protein family</a>  <font color="#6f6f6f">Nature</font>

Genome-wide analysis of the U-box E3 ubiquitin ligase enzyme gene family in tomato
Naturegeneral

Genome-wide analysis of the U-box E3 ubiquitin ligase enzyme gene family in tomato

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5tcGxTdmdULU5XeG9Ua1BOU1p5dVF0bThPeXpFLVF4Umd6YTFlZm01MEV4eGJ5cFF1NFREcjRGdlFiQ2trTkt0RC1ZVGhFTm5Ma21rWmpkOTJtbTNMMkU4?oc=5" target="_blank">Genome-wide analysis of the U-box E3 ubiquitin ligase enzyme gene family in tomato</a>  <font color="#6f6f6f">Nature</font>

Inhibition of HECT E3 ligases as potential therapy for COVID-19 - Cell Death & Disease
Naturegeneral

Inhibition of HECT E3 ligases as potential therapy for COVID-19 - Cell Death & Disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBNQ2ZCdzdvZzJKU2liajNDWThKRkZGZFJiMjVFWjFoSTBPVjNNR2QzcHM4dFRNMUFxSXQ1U0sxcDlMT1Mybi1DS0FaTWFFdHlLcDhYSTNzb21vTmFpeTcw?oc=5" target="_blank">Inhibition of HECT E3 ligases as potential therapy for COVID-19 - Cell Death & Disease</a>  <font color="#6f6f6f">Nature</font>

The E3 ubiquitin ligase TRIM56 promotes aggregation and activation of Src protein through Lys63-linked polyubiquitination in hepatocellular carcinoma
Naturegeneral

The E3 ubiquitin ligase TRIM56 promotes aggregation and activation of Src protein through Lys63-linked polyubiquitination in hepatocellular carcinoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9jU2diOXVnVzNEbDFkRXNJMXloU090UTJpNVV2cFNndk9sWk9HaVB0VHZVSlpPaldvTUh6bFMyelQ3N3hSN09FaHAyZ0NJcmYzQl9FZ01GQWg5RlM5YzFr?oc=5" target="_blank">The E3 ubiquitin ligase TRIM56 promotes aggregation and activation of Src protein through Lys63-linked polyubiquitination in hepatocellular carcinoma</a>  <font color="#6f6f6f">Nature</font>

Protein neddylation and its role in health and diseases | Signal Transduction and Targeted Therapy
Naturescience

Protein neddylation and its role in health and diseases | Signal Transduction and Targeted Therapy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5taXIzU08tSXVZSHZqcUVST1JxLVdaWGZTV0VPUDlGQUx5V0hEQ3N4SGZtVUU4Rm8zM182SU9CbHhybThvbjNlZmg5T1ItU2xlM1BJWGpaVk4tbFZJREZZ?oc=5" target="_blank">Protein neddylation and its role in health and diseases | Signal Transduction and Targeted Therapy</a>  <font color="#6f6f6f">Nature</font>

The ubiquitin ligase RNF181 stabilizes ERα and modulates breast cancer progression
Naturegeneral

The ubiquitin ligase RNF181 stabilizes ERα and modulates breast cancer progression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5TaFdqaG5VQm52UnRYMWFvS3ZPY0owRjdKMElRci1YbC1fTVE4Z0xMOHJLYjYtNzNQNDNPak5BRTQ0ckpBN0lfaUZKMXhwQlN1YXkzcVNEVDRqN2xfbU9r?oc=5" target="_blank">The ubiquitin ligase RNF181 stabilizes ERα and modulates breast cancer progression</a>  <font color="#6f6f6f">Nature</font>

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency
Wiley & Sonsworld

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

<a href="https://news.google.com/rss/articles/CBMiaEFVX3lxTE1CQVlUTXEzSm9DdlNZTUtxLVlpeGVJQl9hMWYyMm9CUnpsNU5QYzZ4RU1qWGlwbWhjQ2U1MkR2WGhodmlqeU5uaGxYZlNyY1Jld2hLdUdJTXdGMzNMTlFDOHFnLUpKZ1dK?oc=5" target="_blank">Loss of E3 ligase HvST1 function substantially increases distal crossover frequency</a>  <font color="#6f6f6f">Wiley & Sons</font>

Neddylation, an Emerging Mechanism Regulating Cardiac Development and Function
Frontiersworld

Neddylation, an Emerging Mechanism Regulating Cardiac Development and Function

<a href="https://news.google.com/rss/articles/CBMikAFBVV95cUxPSG1iLS1CaGZycEszMTQ2RzlLMExOTFlQRUVuckI0T2NLSzl6aXQtS29TMVNfZ2RVTEVkYUpTOW1aU19hRGxSeDJHdkMtM2pMcTJjSE9od283LW1TUlI4Y2VmdUtrOS1yakhUZTBlNjN4Q29VaGE0YlpubkNDdFhSVDFaSnBjbHBKTi1KWGxRU0w?oc=5" target="_blank">Neddylation, an Emerging Mechanism Regulating Cardiac Development and Function</a>  <font color="#6f6f6f">Frontiers</font>

Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
Wiley Online Libraryscience

Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE5fbDRkdjZ4RFlla080YmhXSVVmNEM5ZXlCeS02aUxvSGVIN3JxODRqX3ZjTE0wNHBTVGZ0U3NUM19QV2w2SWxiOC1NWFJTT3V4STJyZ3N6RW1xb1l3SExJSnktMVYyNHlFdEE?oc=5" target="_blank">Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space</a>  <font color="#6f6f6f">Wiley Online Library</font>

E3-ligase knock down revealed differential titin degradation by autophagy and the ubiquitin proteasome system
Naturegeneral

E3-ligase knock down revealed differential titin degradation by autophagy and the ubiquitin proteasome system

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE56Rk9FaXpfZ0FBRU0tQTUwc0EtcTRxVlJNTU9sM0ptdFJvU3FuTVc2WVRYUnRObGVyY2dNQzRfbTBteE9JZmFYQ2FPQmFzNXJnV1JQWEI5MnBKemxSNHF3?oc=5" target="_blank">E3-ligase knock down revealed differential titin degradation by autophagy and the ubiquitin proteasome system</a>  <font color="#6f6f6f">Nature</font>

The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression
Naturegeneral

The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9uRGxWRDIweVRMdVNkRWl6aURKNmJhRURUV0trNWI2WHBxb3pxeVVKX1pFZndQeTJfcFBXSF9WeUFZRnZaUEIwQjhGTnJBY1lpSXZSMEwya0lxZVlDTzZF?oc=5" target="_blank">The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression</a>  <font color="#6f6f6f">Nature</font>

Discovery and characterization of noncanonical E2-conjugating enzymes
Science | AAASgeneral

Discovery and characterization of noncanonical E2-conjugating enzymes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAxQm5WOWxDUXphRE1sY2N6U2J6NVEyeUloTXNSbjh2U2hzVW1UUjhGUjdLQ1RmNGN0Zk9URmZLc1VUSmZiOU1oMHNFaVRlSERncHdHQ3pvQVhDT2dwZmh3?oc=5" target="_blank">Discovery and characterization of noncanonical E2-conjugating enzymes</a>  <font color="#6f6f6f">Science | AAAS</font>

LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism
Naturegeneral

LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1jSzNYeVhFVUc5RzdaOEVsdmUxRHpuOWdYSkVudi1SNG1GZS0tU1FhVFNxZm1jRW9oYUY3UWNLZ1ZEWU9lR0Y2cFF4Q3I5dW9DZEdZZ0oyTmhxOHB0Szhz?oc=5" target="_blank">LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism</a>  <font color="#6f6f6f">Nature</font>

CRISPR-Cas9 screening reveals G2E3 as a novel ubiquitin-linked factor controlling autophagosome-lysosome fusion and cancer cell progression
Naturegeneral

CRISPR-Cas9 screening reveals G2E3 as a novel ubiquitin-linked factor controlling autophagosome-lysosome fusion and cancer cell progression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAtRlJITm1pTml1WFkwdmVSN3MyWTZtRktOOTJlR01jbVB2WUhWaXU5TGRYM2xzRWtRSmRyWmxJdmlmUjZYUTVmdmtmM3hzWkx4TlpkZkZDQUk5SmlITWtB?oc=5" target="_blank">CRISPR-Cas9 screening reveals G2E3 as a novel ubiquitin-linked factor controlling autophagosome-lysosome fusion and cancer cell progression</a>  <font color="#6f6f6f">Nature</font>

E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis
Naturegeneral

E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1WZ2s3ZzgzNjRyLWkyVjFkZUljWHRyS0poalU1MXRRU3lELW1tNVNOcHhaTU0yQ05JODEyM2JjZG45ck5qUFdWVDh3TW5zSmxOc2JvbVpwcTVHbHlMN3p3?oc=5" target="_blank">E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis</a>  <font color="#6f6f6f">Nature</font>

Linker-free PROTACs efficiently induce the degradation of oncoproteins
Naturegeneral

Linker-free PROTACs efficiently induce the degradation of oncoproteins

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFByZkk1bHB6ZnBaLTV2N1hMVklJbnRvNjhxWG00NXNzeE1FOUdGRFNtUFVmeVVzQmJBdW1NV3FZSXd5MXF0bTdOQkFnYVF3ZW1zOXg0ai1yazVEY3l2aXB3?oc=5" target="_blank">Linker-free PROTACs efficiently induce the degradation of oncoproteins</a>  <font color="#6f6f6f">Nature</font>

Deciphering the mechanism of E3 ubiquitin ligases in plant responses to abiotic and biotic stresses and perspectives on PROTACs for crop resistance
Wiley Online Librarygeneral

Deciphering the mechanism of E3 ubiquitin ligases in plant responses to abiotic and biotic stresses and perspectives on PROTACs for crop resistance

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE9FeWJib19zNE5NYUdPQVc3V0xaZ29PeGlVb3gzNURnODhSTENXaDBET2YyRVBUaXRXQnlZOGJSYWgxeGJlQUVoNS1RekJMWnh1dEFaX201YVk3M2lDb3pUOUEyd3RZQ21zY2c?oc=5" target="_blank">Deciphering the mechanism of E3 ubiquitin ligases in plant responses to abiotic and biotic stresses and perspectives on PROTACs for crop resistance</a>  <font color="#6f6f6f">Wiley Online Library</font>

"Identification of E3 ligase su" — Live Google News Trends & Headlines