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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "How conformational change" (30 stories)

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How conformational changes near the F pocket of MHC class I proteins mediate chaperone assisted peptide loading
Lead StoryFrontiersgeneral
Nov 25, 2025

How conformational changes near the F pocket of MHC class I proteins mediate chaperone assisted peptide loading

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxOanpYV3U5UnNBeVlLTmZ3X0ZuaHVrQ1MzMEhfbXpnTWk0aFRlelgwSlN5N1FhSnFwWnZOYjQ4bXVqUWN6ZzIyMkVTSUZlLUhnLWtLV2ZFRm9SOXFtUzFENVB1MTIzeGpIQnptejVERTBxdjBjM0N4MVRKX0hWdkc4cFZ6NWFNdFJISnJiWFhFRlRJdw?oc=5" target="_blank">How conformational changes near the F pocket of MHC class I proteins mediate chaperone assisted peptide loading</a>  <font color="#6f6f6f">Frontiers</font>

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Search Results for "How conformational change"

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29 stories displayed
Conformational switch upon substrate binding informs the rational design of CCoAOMT enzymes
Naturegeneral

Conformational switch upon substrate binding informs the rational design of CCoAOMT enzymes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5hQms0bUJqamIyOUtpYWhrMWN6LWlQZ2NFWUNiekIxcVZUYTFybWxGcjBRaXlXQ1M1NE84T3pOa2ZhT3FoY0V2Z0l4Vi03NGF5d2N2TmFHMUhPZk9TUS04?oc=5" target="_blank">Conformational switch upon substrate binding informs the rational design of CCoAOMT enzymes</a>  <font color="#6f6f6f">Nature</font>

Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit
PNASpolitics

Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1mQi1jMnJMemtuUzRaWDRScFV4MWJyTm1fMFdIdkp0VVpzWEM1NWFoNHNyZDh4MThldGlKZVZUZ3MyOTdla3FyajJ3M1BtSUxwaG1ZaXFrRTh5RlBq?oc=5" target="_blank">Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit</a>  <font color="#6f6f6f">PNAS</font>

Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping
Rockefeller University Pressgeneral

Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxOOExIandhZC1nQjNOVmZPUHROUHZ0NmtBWlhWMld6MEhSU0VmSzFzUklGcm15QVc1ajJEOU5HaUFGa0tRZFBZQTlPRU02UWRHUEZTeHp4Rm41THVIYkpmeFVrSVBEQ0o4UWFXVmZQclFMMzk2NzdZQ0E4a1VLRm5pSFVYMlB3MS1oUzdFSTAyMjlRLTJkYUFBemFxOTVKZw?oc=5" target="_blank">Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping</a>  <font color="#6f6f6f">Rockefeller University Press</font>

Concerted conformational changes control metabotropic glutamate receptor activity
Science | AAASgeneral

Concerted conformational changes control metabotropic glutamate receptor activity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5iRkV6dkNXTEFvNk9BbnBNZ09qeFlLc2YzaE1vT0d1bmItOFBmdWZyOWZPX0NQQkF0TV9WcGFLZFl2cnprMGZLNThiMkVtQ0dGZXNzR2o3RWppa3RFZU40?oc=5" target="_blank">Concerted conformational changes control metabotropic glutamate receptor activity</a>  <font color="#6f6f6f">Science | AAAS</font>

Ligand-specific conformational change drives interdomain allostery in Pin1
Naturetech

Ligand-specific conformational change drives interdomain allostery in Pin1

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBZUllJS3NUYXpUakcxczVFM2RCeGlJYTc3dk40X3FjTGhlSXNJWkd3cldsYmZhQXMwWkVXZmxYU041ci1VU01WZ2ZzcFVEQWRMNGhsN1VBVmFuZkN4VS1Z?oc=5" target="_blank">Ligand-specific conformational change drives interdomain allostery in Pin1</a>  <font color="#6f6f6f">Nature</font>

Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit
PNASworld

Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1kN25HMjR6cWxVYzFnSjNEaUNaR2I2blVLS2xIaHBnQTg2SmdxM01ZUHROMGFQc0FJVUZ6YkJQOWRlQlkyTndpOXJmM0d0RzRLekRJdmpEX2xESGI4?oc=5" target="_blank">Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit</a>  <font color="#6f6f6f">PNAS</font>

Large-Scale Conformational Changes and Protein Function: Breaking the in silico Barrier
Frontiersworld

Large-Scale Conformational Changes and Protein Function: Breaking the in silico Barrier

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxPQUdmMTRCX091alZITXRLLTZxUmdWUnJDU244ZGI2M0RaMFdEMlhRSHpBeGktUThMS0ZLcHdvYVFGR3FmQ0EzT0hPU25Qd2hSWU44RGwzZGRITU9mc0VTZ25LUGhhenVjSE1OckNNd3Z0a3VnY3QwNEdiQXdaNFUybnF6V3BSY3ByTDF0UDdqN2RRNHdlWEhfVVVwaUVmZw?oc=5" target="_blank">Large-Scale Conformational Changes and Protein Function: Breaking the in silico Barrier</a>  <font color="#6f6f6f">Frontiers</font>

Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin
Rockefeller University Pressworld

Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin

<a href="https://news.google.com/rss/articles/CBMiqAFBVV95cUxQWWhkNHUxRWZzYWo1MWxFdlp4Z0g0NFctY3BxZjNaQXI5YXNSTlktcHZSenN1XzQ2OXlqZEFZYW9NVkdFNTREQ3QwWXVNSUxRbjc4MGZSalRRUE4tZndlUmZ0VXlpaDdLYmE1YUY1YTl4Y1pYOHlqY28xX3JKNDgxalh1ZERYX3RXekVRUC1PQlpzWFlBbElqc2ktc21JZmFXeG83ZWRrWEo?oc=5" target="_blank">Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin</a>  <font color="#6f6f6f">Rockefeller University Press</font>

Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry
Naturegeneral

Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBhUXI4bUNUZ2lYbFBGaXpYaDFsUDlSLTR3dXB0c1NydkN1N1NscWpEenZOMTJuWEptS18tVWNZZnVvZy1JNmhiU0VfZUkzSVJSSzlRWUF2OG44YVdKMXE4?oc=5" target="_blank">Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry</a>  <font color="#6f6f6f">Nature</font>

Ligand-induced conformational changes observed in single RNA molecules
PNASgeneral

Ligand-induced conformational changes observed in single RNA molecules

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFBtbnBvTlpNLUduV0E3QWdOQmtlQmF5cVlySWZjeGpKM3pKVElSLU8xVVQyTHVaMGtkTVA1RUJmbDZqcXlJZ3lFMEFSTjl3SW9MNGJwMElNRU1rOF81?oc=5" target="_blank">Ligand-induced conformational changes observed in single RNA molecules</a>  <font color="#6f6f6f">PNAS</font>

Monitoring protein conformational changes using fluorescent nanoantennas
Naturegeneral

Monitoring protein conformational changes using fluorescent nanoantennas

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5zQTFXXzVhUWZ3VDRpaUhJWmZGNXZnOEZMQ1ZGZE14dUw2YnhkZWlrX0s2U2toT08wWWNiZDBuSXppZUhYSDhSNGp6dDlaUlhMaUhfaUxfczc0TzhaOU5j?oc=5" target="_blank">Monitoring protein conformational changes using fluorescent nanoantennas</a>  <font color="#6f6f6f">Nature</font>

Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer
PNASgeneral

Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE5BMjZSMkhjcllrNzBmNkl6a3JRZHZsZnBRNC1fUjdMdUJRTW1DUU9CWmdfNmxDQ1pQWGtQZE9mV0N4SW9SQ0Y2TW02MXhLd0RvcEV4ZjhkS3g3eHEy?oc=5" target="_blank">Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer</a>  <font color="#6f6f6f">PNAS</font>

Structural mechanism of a drug-binding process involving a large conformational change of the protein target
Naturegeneral

Structural mechanism of a drug-binding process involving a large conformational change of the protein target

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9hQVVJb0Zyc3p3VnhmSzI2OW9Mdi00V00tVWUyMVRfRFJvcUdKZ2JDRWc1aGduWjE4VndXa0ZRRlFMT2UyVVlxWkxKZHFIa251a1JxWmJ6R0VEOWpQZVkw?oc=5" target="_blank">Structural mechanism of a drug-binding process involving a large conformational change of the protein target</a>  <font color="#6f6f6f">Nature</font>

Mapping temperature-dependent conformational change in the voltage-sensing domain of an engineered heat-activated K+ channel
PNAStech

Mapping temperature-dependent conformational change in the voltage-sensing domain of an engineered heat-activated K+ channel

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFBpeHNDZHBZYU1GZUNBTjF6TGFWNkZobm4wNWpqSWZmRVpUcDFrNkxZVWJRMjRVZ3dzMGNPTWo1cjAzdTJmVEEyc092Z1pFTVZNQlp6LTNZdGg0NXly?oc=5" target="_blank">Mapping temperature-dependent conformational change in the voltage-sensing domain of an engineered heat-activated K+ channel</a>  <font color="#6f6f6f">PNAS</font>

Conformational changes in the motor ATPase CpaF facilitate a rotary mechanism of Tad pilus assembly
Naturegeneral

Conformational changes in the motor ATPase CpaF facilitate a rotary mechanism of Tad pilus assembly

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBfQXFRUkpsVU1NV19UaFVtckIzTmtEXzg4UE53WWxLNlhkWUtTM2hQTnFuQkk0ZGZ0ei1QT01QbEJZNWVmbnpPOTJrc2xobUlhTW51eDNreC1rd2V2TDBz?oc=5" target="_blank">Conformational changes in the motor ATPase CpaF facilitate a rotary mechanism of Tad pilus assembly</a>  <font color="#6f6f6f">Nature</font>

Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release
Naturegeneral

Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1ucUJhNlh5ZDdiNzFrbkhVOEdYUHRoSXJuYjRJczB2WHpaUjk3bl95SHVKMkdvLVg1WEpEaU5wUGc2OXBLMmEwSm1rc2lLdXV1VGtBS1BlcDRCWFg1TnlR?oc=5" target="_blank">Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release</a>  <font color="#6f6f6f">Nature</font>

Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome
Naturemarkets

Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE55Smp2LWttTVZEd3JaTlRnZVhpYUd4MGg4aGJUMURRVTVYWEpubkJxMVAtRmJzS08tWG9kVmlwa01nRFVuWHNmNDdVTnYzaE56N0ZEQTRORUVRWk1VT0xv?oc=5" target="_blank">Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome</a>  <font color="#6f6f6f">Nature</font>

Ligand-driven conformational changes of MurD visualized by paramagnetic NMR
Naturegeneral

Ligand-driven conformational changes of MurD visualized by paramagnetic NMR

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE5OWGd3WTJOMHhzR2JxemZxMV96dzM2c290aEkyMFk2SHVpbkhnYi1LNW9yVVFvV19mNTUtV3JCaWxDOEs5TjE5ZktZdHN6cy1ING1n?oc=5" target="_blank">Ligand-driven conformational changes of MurD visualized by paramagnetic NMR</a>  <font color="#6f6f6f">Nature</font>

Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains
Naturetech

Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE1Zc2kwMWFPNFNZRlluWkVVaDdlZUhadWRHWndWUUg0bDg2RWsxVVpLdDEwdzRfWjlqVW5ybkJnSkF3ejFCdFp5ZHdRRjBURlNqME5j?oc=5" target="_blank">Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains</a>  <font color="#6f6f6f">Nature</font>

Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation
Naturegeneral

Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9sZWdMUWQxSUVrRW8yZ0xqc01NaUlfRUhWS3d4bjFqNVRkM3hGbkM1RGNPWGpONTk1bGlNT003Q1FFVWhxWkc0WDVaSzJqMmlVVWFTT1BrLU52Q3pWYUdZ?oc=5" target="_blank">Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation</a>  <font color="#6f6f6f">Nature</font>

Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding
Naturegeneral

Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE9CTngzbDdZekJJbUZiOEVpWDJJUFF0QVFtbWJ3UVIzT0Q0eUY4WUZXU2dYSkxhZUdWbXE2eG1iQWp5NDRaSERiZHA4S0pCVW9JdnFZWHFR?oc=5" target="_blank">Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding</a>  <font color="#6f6f6f">Nature</font>

Adsorption and reversible conformational change of a thiophene based molecule on Au(111)
Naturegeneral

Adsorption and reversible conformational change of a thiophene based molecule on Au(111)

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBtQnNjUHV1Sjc2WU54NWhmZEI4alpiclB6R0ZUV1REay1YZEd0X3BFVTNyNDRuQU9JT1R3YzgzTkZ4TWF6UTd0NzctYkcyZ0QxWHRsTXJKNnFhWmpRM0dV?oc=5" target="_blank">Adsorption and reversible conformational change of a thiophene based molecule on Au(111)</a>  <font color="#6f6f6f">Nature</font>

Phosphorylation-mediated conformational change regulates human SLFN11
Naturegeneral

Phosphorylation-mediated conformational change regulates human SLFN11

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5Qd2Mta2ktb0JpeHpiSTY3TmR5VU5uZzZhVzRxYWI3WXJaVWc3WlFpaldxQ1lRcXlDSjFVZndwams0WURncEtxalJWOVJveExCYVBhMEliTVZXeTBweEVF?oc=5" target="_blank">Phosphorylation-mediated conformational change regulates human SLFN11</a>  <font color="#6f6f6f">Nature</font>

Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space
Naturescience

Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1CaFdqT2FxNnRONGF5UEVWUHNMUjM0YW5TQ01vQjNBak1zZkotb2VmbnY0Qm1RRHlEb2p0QnkwTEp1OGZuM2JnTVg3NG10akE0VU1TTFhLZV8yTU9OQ0pr?oc=5" target="_blank">Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space</a>  <font color="#6f6f6f">Nature</font>

Actomyosin forces trigger a conformational change in desmoplakin within desmosomes
Naturegeneral

Actomyosin forces trigger a conformational change in desmoplakin within desmosomes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFAzdTEwY1NVMDc3T3dHNzlwZ1J4dURZOVR4RWs4SHl6Q1ZqY3FzZENwblJTREI3RklXQXhOTWx4cWhSYWxxS2N6RTVua1BuTjg4VEFHemNLTkxnQmRIaTZZ?oc=5" target="_blank">Actomyosin forces trigger a conformational change in desmoplakin within desmosomes</a>  <font color="#6f6f6f">Nature</font>

The bright and dark sides of protein conformational switches and the unifying forces of infections
Natureworld

The bright and dark sides of protein conformational switches and the unifying forces of infections

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE5mVlJqR1F5bEtZZTlTeFBxUHFLSGdFWlExVURwUlpjbmpDVGN3RlV2NVd0dmw2UFlWR2dfNmI0a2RlR29hWUVUdXFCLVFNUV8zQVFzMWlNWEt2VFZvVXc?oc=5" target="_blank">The bright and dark sides of protein conformational switches and the unifying forces of infections</a>  <font color="#6f6f6f">Nature</font>

Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes
Naturegeneral

Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE85NzU2cl9oSzQ3RE12OU5yZWczSlRHWk5CX01zUVFkLXZSYmx1anZKSEVNUUxCWkFrS3g5TnAxVXJMTG1tdVRQZTEwNG5ad0dQTktaNUp2T3V3TF9VM2c?oc=5" target="_blank">Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes</a>  <font color="#6f6f6f">Nature</font>

A large conformational change of the translocation ATPase SecA
PNASgeneral

A large conformational change of the translocation ATPase SecA

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE5tdmpBdGFCVmdpMFBtSlFIS0dCdHRzcV9iSTYzYWgwOEhKaGo1Qkd0LUhPamctWWFmanVkM0t4QXcxYU5aaG90Y21pZGxJakRSdkhfazFBbkpoYmZn?oc=5" target="_blank">A large conformational change of the translocation ATPase SecA</a>  <font color="#6f6f6f">PNAS</font>

WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction
Science | AAASgeneral

WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTE5ubHRaSTFOTGlGSi1BYjNON25KVXJSMFV0ekRDaXB6WTR1cWNLVEpnWGdrQ0VVZWFzX1Z2Q2dPSnUzcWZSSXRZNGw2TFFzWVMzYVZaRXRRX0FQOFlCSnhFVEJ4Zw?oc=5" target="_blank">WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction</a>  <font color="#6f6f6f">Science | AAAS</font>

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