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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "DICER1 hotspot mutation i" (23 stories)

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Human DICER1 hotspot mutation induces both loss and gain of miRNA function
Lead StoryNaturetech
Nov 4, 2025

Human DICER1 hotspot mutation induces both loss and gain of miRNA function

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5hX1hzUnNlTGdmTWtybXdMR2JqVlpvOHc2QmhKLXFFTWlxSWVnaWtKaTJfWHF0R3BiM1pWYjdYLTVTUkowVkowR3B1TUE4NkxFRFdZYlAzdFdMZGNoX2JR?oc=5" target="_blank">Human DICER1 hotspot mutation induces both loss and gain of miRNA function</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "DICER1 hotspot mutation i"

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22 stories displayed
Case Report: DICER1-mutant primary intracranial sarcoma with concurrent TP53, PDGFRA, and KEAP1 somatic mutations in a 5.5-year-old boy
Frontiersgeneral

Case Report: DICER1-mutant primary intracranial sarcoma with concurrent TP53, PDGFRA, and KEAP1 somatic mutations in a 5.5-year-old boy

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxQSVdDMVZ6VUpNYWtMdGRwaG5UamtLT0tlQmNwT1JUbVpaSW9NeDhCNjZmTjFnekU2OHYwcUdiS0JianlvTmFEUUNneElxdC1MeTdsRWtYTy0zSGhEYnJXeUJLdTdENXZ0ZW53cVg4dGsxbEhBRXRqemRrYm1GWVFsa3Z3ZWgwaTJWdm16YlVR?oc=5" target="_blank">Case Report: DICER1-mutant primary intracranial sarcoma with concurrent TP53, PDGFRA, and KEAP1 somatic mutations in a 5.5-year-old boy</a>  <font color="#6f6f6f">Frontiers</font>

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DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switch
Naturetech

DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switch

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9RQURGYlFRRlN5cHJZam9YNE8xZ1l0QVdrSHd5UHVSSFpQTXVtOG0wZ0ZHMnJ4dV9fY0N4S3RUODJkakVWRjVERUd1dGRnM2UwNElHdlJQT3hFdFNwbVdj?oc=5" target="_blank">DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switch</a>  <font color="#6f6f6f">Nature</font>

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DICER1 -related tumour predisposition mutations increase 3p-miRNA function and HERVH activity
Natureworld

DICER1 -related tumour predisposition mutations increase 3p-miRNA function and HERVH activity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE04aEl1V1dzQVpNWEUxdkZ4ejB2S1EyVzFFQVdRcG9sZ2VBT2s0cmIyYU9DU21kaUdQQTJ3cG9TQ0labkJHbkpZcW94akNudmFPSDJuUHZVVWl0ZXFBQU44?oc=5" target="_blank">DICER1 -related tumour predisposition mutations increase 3p-miRNA function and HERVH activity</a>  <font color="#6f6f6f">Nature</font>

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Somatic DICER1 mutations in adult-onset pulmonary blastoma - ERS
European Respiratory Societygeneral

Somatic DICER1 mutations in adult-onset pulmonary blastoma - ERS

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTE95LW5ndnFsQS1tbG9Zd1RZXzhwaGhabmtka2VzX241R1k4ZEIwZGJzTzlKMTVOVGV1bVE1bllMZ2xzRHRTdXRVR0k5OEU0b3p6WjNvaWRBWm9BdEVCejlZdnVBNA?oc=5" target="_blank">Somatic DICER1 mutations in adult-onset pulmonary blastoma</a>  <font color="#6f6f6f">ERS - European Respiratory Society</font>

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Thyroid nodules with DICER1 mutation or PTEN alteration: A comparative cytologic, clinical, and molecular study of 117 FNA cases
Wiley & Sonsgeneral

Thyroid nodules with DICER1 mutation or PTEN alteration: A comparative cytologic, clinical, and molecular study of 117 FNA cases

<a href="https://news.google.com/rss/articles/CBMie0FVX3lxTE1QRm1pVmRDbzhEWDEwSGRSVXNySHg4WVVOVk1mcEw0S1RWdU5kb1JFRTI0MzhBZjkyYmtpRURIMUdDT1pjTGpVWFVHTXFOc2JzODd1QUVBX0NONDVPTWlUM0tseV9vOTRYaU5nOW5WWnU3UG94T2hVRDRKYw?oc=5" target="_blank">Thyroid nodules with DICER1 mutation or PTEN alteration: A comparative cytologic, clinical, and molecular study of 117 FNA cases</a>  <font color="#6f6f6f">Wiley & Sons</font>

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DICER1 Mutation-Associated Follicular Thyroid Tumor With Bizarre and Pleomorphic Nuclei
Cureusgeneral

DICER1 Mutation-Associated Follicular Thyroid Tumor With Bizarre and Pleomorphic Nuclei

<a href="https://news.google.com/rss/articles/CBMixAFBVV95cUxNTWg5QlR3aDgxbmlwVVQ1dndIMUc1cnoyS2xYOWN0eml3LTdrYWpGSGVObjRwOUVIZjc4ZHNkRXFFRXFYNmpDNDMyUjNQbVI2blFUdndTdjRHZ05adzUxR3NmVk9qMWMtV1hmaXFsd0NlOS1hV3ByMi1iN1JhTURVNGYwdWNnTXpkaDNaMXJMV0ZJeklMYnRzbXNXOVZBY1dQd29vanlzeXNoWUdfbHBQdU5qLUpqcGZxQ3Z3QklmMXJXUGpJ?oc=5" target="_blank">DICER1 Mutation-Associated Follicular Thyroid Tumor With Bizarre and Pleomorphic Nuclei</a>  <font color="#6f6f6f">Cureus</font>

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DICER1‐mutated rhabdomyosarcoma of the ovary with teratoid features
Wiley Online Librarygeneral

DICER1‐mutated rhabdomyosarcoma of the ovary with teratoid features

<a href="https://news.google.com/rss/articles/CBMiakFVX3lxTE1CVzZyR2dvV1ZkTHlGVUptNFJ2OUhRcnpEejl5SzRMMHpueVBGb2Zwc21qR2RaRWs3M3NKSHhSQUY2Q1BsRlZfOU1fRWpoSms5SjczUlJtN3Z3QmpnWW1uLXEyM081U2dvTUE?oc=5" target="_blank">DICER1‐mutated rhabdomyosarcoma of the ovary with teratoid features</a>  <font color="#6f6f6f">Wiley Online Library</font>

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Congenital midline spinal hamartoma in an infant with DICER1 syndrome: A case report
Frontiersgeneral

Congenital midline spinal hamartoma in an infant with DICER1 syndrome: A case report

<a href="https://news.google.com/rss/articles/CBMijAFBVV95cUxOWXVWUDBiRWhqM1Jjb09kU051cjdaT3V5X3VwWU9GR2tkQ1JTVVA3SzZHZTVWU013RDU0OGJfeDhkbXEwTnV2b3JuRWd3T2RGOGxvaEhVUHkxVzFJZjVjS0RvZXlJR0lGdnpockVjeHFUdUVzUVNVOWNPQzNmOEFzN29YRWo1NmhsOGxfSg?oc=5" target="_blank">Congenital midline spinal hamartoma in an infant with DICER1 syndrome: A case report</a>  <font color="#6f6f6f">Frontiers</font>

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Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis
Naturetech

Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBOdzUyRVRMZDI3dnBKMnU0bmNkd2tJbzJXYUZCVTVpNzRaUnlqenNSR3lrbFh0LXdwd2kzZndQZE1fckdGY19LM0luOXRBWFpBY2pwMmRUcVFsZjZ4ZWhF?oc=5" target="_blank">Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis</a>  <font color="#6f6f6f">Nature</font>

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Primary central nervous system sarcoma with DICER1 mutation—treatment results of a novel molecular entity in pediatric Peruvian patients
Wiley & Sonsgeneral

Primary central nervous system sarcoma with DICER1 mutation—treatment results of a novel molecular entity in pediatric Peruvian patients

<a href="https://news.google.com/rss/articles/CBMie0FVX3lxTE1JbUNaSlZUVUd3dDFrWlJvMmZzV2RDajBBRG01cGFXcEJyZ2dDY3RqcmU4cTZYZlBSR0R5NE45YVlGOWRQNnE4R2o4NnhFQi05aU52RG9oNHM5SURSbHFRX192RC16MTdMVUprVE8wQ0NUN2tfUTJhckQydw?oc=5" target="_blank">Primary central nervous system sarcoma with DICER1 mutation—treatment results of a novel molecular entity in pediatric Peruvian patients</a>  <font color="#6f6f6f">Wiley & Sons</font>

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A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors
Naturegeneral

A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1ZOVhqVXBTajNwNnp3VzhHbG4zUUFaM3phYTl1Y3JjZVh2NXBHTWJoR3NFNDQ2NWJibUtqYXpHQllndXdKS3hONUpxZnpvZWVSb3JNb1NnLWMtSFZL?oc=5" target="_blank">A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors</a>  <font color="#6f6f6f">Nature</font>

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Thyroblastoma in Pregnancy: Expanding the Cytomorphological Spectrum of a Novel DICER1 ‐Associated Entity, a Case Report and Literature Review - Razack - 2025 - Diagnostic Cytopathology
Wiley Online Librarygeneral

Thyroblastoma in Pregnancy: Expanding the Cytomorphological Spectrum of a Novel DICER1 ‐Associated Entity, a Case Report and Literature Review - Razack - 2025 - Diagnostic Cytopathology

<a href="https://news.google.com/rss/articles/CBMiaEFVX3lxTE16YXV3NmYxcVhmYUpXVWNoaGlwSGJoc2JLcXhtaUVoc1FXYWpRVUdGbllsbWtoN2RWYnBTS1NtdXVYS19qaVBxd3hHZE1ISFJRSjlMTk5CR2xlZ2pZMy1YVFdJamZYdUxS?oc=5" target="_blank">Thyroblastoma in Pregnancy: Expanding the Cytomorphological Spectrum of a Novel DICER1 ‐Associated Entity, a Case Report and Literature Review - Razack - 2025 - Diagnostic Cytopathology</a>  <font color="#6f6f6f">Wiley Online Library</font>

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DICER1 hotspot mutations in non-epithelial gonadal tumours
Naturegeneral

DICER1 hotspot mutations in non-epithelial gonadal tumours

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE5kdUh5ZUp3Q3BQSXJRUnJQazdqZmRER3V1NExPdklJdl9INURCWEZ0aFprTXZCc3dzZ3Y5dWNnWUUzUnhtWS1lZ2VYLXN0NFdkM1MtSQ?oc=5" target="_blank">DICER1 hotspot mutations in non-epithelial gonadal tumours</a>  <font color="#6f6f6f">Nature</font>

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Genomic characterization of DICER1-associated neoplasms uncovers molecular classes
Natureworld

Genomic characterization of DICER1-associated neoplasms uncovers molecular classes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE82V2xfYWVnMWxGYTJOel91TktraGt1eWdpNXFlaFpMbTQ4VXYwWVJ2SXcyUmNJTTN3OWl6M2F4S1lkbG5DV19BMGFKOFhRZzIwNnJpeldsYXk1bTk5VkJ3?oc=5" target="_blank">Genomic characterization of DICER1-associated neoplasms uncovers molecular classes</a>  <font color="#6f6f6f">Nature</font>

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Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma
Naturegeneral

Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE40TTBSU0luQkVlRXd3ZkpSYmNSWUFsWU5vYXRuamx4eFl4aVRfS012MEYtX3o0N2FseFEwYURyU3kzVWxiM0ZlSlBDeEdQUFJpdjVKLQ?oc=5" target="_blank">Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma</a>  <font color="#6f6f6f">Nature</font>

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DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma
Naturegeneral

DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8yREthZW1IaFFkQ3lSdlZVWFRJRW5UWjFhcWtaaHRxMkxfZE5OM3RRWDNUWlhOS01HX09jUVVJekxLNjhaWkQwMk9JNnVhbUdYeWlsTWpQc2gwNzRNWDVr?oc=5" target="_blank">DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma</a>  <font color="#6f6f6f">Nature</font>

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Serum levels of mature microRNAs in DICER1 -mutated pleuropulmonary blastoma
Naturegeneral

Serum levels of mature microRNAs in DICER1 -mutated pleuropulmonary blastoma

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTFBtWjhsMVRCMXVvUS1ya3lXTmRKRTZPR0toMkFYcnhaQVpzWVBRZUN5SVd1aDh5MG92Mnl4cjFrM1NfUGpxb1NGU2NMZmJacUttTG55b3F3?oc=5" target="_blank">Serum levels of mature microRNAs in DICER1 -mutated pleuropulmonary blastoma</a>  <font color="#6f6f6f">Nature</font>

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Structural insights into disease-associated mutations in the microRNA processing machinery
Naturegeneral

Structural insights into disease-associated mutations in the microRNA processing machinery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE15a0NXbWpINE1rUVBlZVg1YmxCVmZCNm12WXloQjdWM3JKR21wV0lfazBXUmZDdkc5NEthUW9TblB4d1pWOTVnd2xyMk1zMlVaeXRObjk2cGdfdXRrYkZZ?oc=5" target="_blank">Structural insights into disease-associated mutations in the microRNA processing machinery</a>  <font color="#6f6f6f">Nature</font>

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Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma
Naturegeneral

Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE40aVlrRTFjemd4SzJpR1NvaGp3NkVEM1lIVHlnQUx3VTFldmgtRnRvMGlrTlY1MEJHQTF1SVJqaU12N1lhMktENGoxRXBIdnk2ejhvQTRBS3hBLTR6Q3U0?oc=5" target="_blank">Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma</a>  <font color="#6f6f6f">Nature</font>

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Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours
Naturetech

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE9iaVk4Y2lQMjAtdnNfb0tpWG5MeFBHMFRtblZWQ0x0Q3U1Tkw0cWJzSEZOcmkxeVZUV3pUTW9NTWZZZTdNZVA4QmpQVUM3WS1FT0lfNg?oc=5" target="_blank">Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours</a>  <font color="#6f6f6f">Nature</font>

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DICER1 mutations in childhood cystic nephroma and its relationship to DICER1 -renal sarcoma
Naturegeneral

DICER1 mutations in childhood cystic nephroma and its relationship to DICER1 -renal sarcoma

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE9obVJsc3Zvd3J2azRsanFZWDNodGlJVnpNRnhOcHVoQUFUSlZUQ3MwQk4wSUZnNEpQZ1RFd0xkM3lHcjR6YWxMREVQX2hiWE9adFpsTW1LTkVYVTFZ?oc=5" target="_blank">DICER1 mutations in childhood cystic nephroma and its relationship to DICER1 -renal sarcoma</a>  <font color="#6f6f6f">Nature</font>

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Ovarian Sertoli–Leydig cell tumors with heterologous rhabdomyosarcoma: Clinicopathologic features and molecular analysis highlighting recurrent genetic alterations
Wiley Online Librarygeneral

Ovarian Sertoli–Leydig cell tumors with heterologous rhabdomyosarcoma: Clinicopathologic features and molecular analysis highlighting recurrent genetic alterations

<a href="https://news.google.com/rss/articles/CBMiY0FVX3lxTFAzRjhmcnByUFYxU1FJYnh3R2VmZEplQmpSQV9RWUphWE1jdFRETWNIVm1Sd3d0VWdNNXJ4eGxrdU01aUVVQnEtMUo4T1NGVWFDZ1E0X2hudDlWT2VWMjNVVWN3TQ?oc=5" target="_blank">Ovarian Sertoli–Leydig cell tumors with heterologous rhabdomyosarcoma: Clinicopathologic features and molecular analysis highlighting recurrent genetic alterations</a>  <font color="#6f6f6f">Wiley Online Library</font>

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