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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Conformational changes li" (30 stories)

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Apo2Mol: 3D Molecule Generation via Dynamic Pocket-Aware Diffusion Models
Lead StoryThe Association for the Advancement of Artificial Intelligencegeneral
Mar 14

Apo2Mol: 3D Molecule Generation via Dynamic Pocket-Aware Diffusion Models

<a href="https://news.google.com/rss/articles/CBMiZEFVX3lxTFBRUG5nYXBnVnN4TTZMM1RROVE3YTBJYnRLc0xmMlU3dlVDamhaeFlZQl95bThwSDFEQXBWLVBzR3NIbHprVzhILU5wQnZGd2JkZmRFWHZpMTMzWGtRY2pRX3pPTzY?oc=5" target="_blank">Apo2Mol: 3D Molecule Generation via Dynamic Pocket-Aware Diffusion Models</a>  <font color="#6f6f6f">The Association for the Advancement of Artificial Intelligence</font>

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Search Results for "Conformational changes li"

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29 stories displayed
Disentangling coevolutionary constraints for modeling protein conformational heterogeneity
Naturetech

Disentangling coevolutionary constraints for modeling protein conformational heterogeneity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9sSGViM0FPVnlrVF9ldnRHeTBLWkF1S0ljeDh6N3lHVEg0TVBwNk5Kdl9ZMzBmQ2FBMlhSd19HUTU5dmhkN0s5eG9HMXFZWU5FSmhHcU13dzZXNW5uM2xn?oc=5" target="_blank">Disentangling coevolutionary constraints for modeling protein conformational heterogeneity</a>  <font color="#6f6f6f">Nature</font>

The G Protein-First Mechanism for Activation of the Class B Glucagon-like Peptide 1 Receptor Coupled to N‑Terminal Domain-Mediated Conformational Progression
ACS Publicationstech

The G Protein-First Mechanism for Activation of the Class B Glucagon-like Peptide 1 Receptor Coupled to N‑Terminal Domain-Mediated Conformational Progression

<a href="https://news.google.com/rss/articles/CBMipgFBVV95cUxNcXg2U0ZZWjd1Yi1iYWotY1pCcnVzZy1MemZEVWtsZmhYTlpud1E0YmFFRFR6bkhORERsS0puY21iOGVYS1RPcjl6Q25vbEo5bVVSd1ZxQjF2Z1VvQUxYUU5aN3FsZkY2NTN1bVRmVVJTLXRzSU5nZmw2WHZVSjd4VlplTEtMMzlNcjFyWEc4ZFcweDI3c0Qyei1MLU5ndG1fQ3pwYXVB?oc=5" target="_blank">The G Protein-First Mechanism for Activation of the Class B Glucagon-like Peptide 1 Receptor Coupled to N‑Terminal Domain-Mediated Conformational Progression</a>  <font color="#6f6f6f">ACS Publications</font>

Conformational Transition-Triggered Thermosensitive Tautomerization in Gold Nanoclusters for Optical Thermometry
Wiley Online Librarygeneral

Conformational Transition-Triggered Thermosensitive Tautomerization in Gold Nanoclusters for Optical Thermometry

<a href="https://news.google.com/rss/articles/CBMia0FVX3lxTE5OMmVZRUNRaHo1VjdLdnhoSVIzVzROZHNZRHhxdm9kdUxLeERzUFgwYlB5ZGlaY1lPdlNRelN4V0RBSDAxS0ZNaWlYQ0gyYXl0NnpGRzgzS2lKUGtrOTExZVBKRXE2T0Q0Q1NV?oc=5" target="_blank">Conformational Transition-Triggered Thermosensitive Tautomerization in Gold Nanoclusters for Optical Thermometry</a>  <font color="#6f6f6f">Wiley Online Library</font>

Conformational changes of globular proteins adsorbed at oil-in-water emulsion interfaces examined by Synchrotron Radiation Circular Dichroism
ScienceDirect.comgeneral

Conformational changes of globular proteins adsorbed at oil-in-water emulsion interfaces examined by Synchrotron Radiation Circular Dichroism

<a href="https://news.google.com/rss/articles/CBMie0FVX3lxTE9LZTRBQ040Q2ZBa0hoMUxGcXJnYnVzVkVkVTM5V19nQTFkSFFRVDQtS0xlcGdQdXdLZ05UTjR0ZDJMUzNRNW95U2F6TV9kWVczMm1GRnB3ME93R3RNNktIYUNpMEh3dGFnV3V6c2puT0gwbUNkbk1NemMzYw?oc=5" target="_blank">Conformational changes of globular proteins adsorbed at oil-in-water emulsion interfaces examined by Synchrotron Radiation Circular Dichroism</a>  <font color="#6f6f6f">ScienceDirect.com</font>

Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation
Naturegeneral

Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9sZWdMUWQxSUVrRW8yZ0xqc01NaUlfRUhWS3d4bjFqNVRkM3hGbkM1RGNPWGpONTk1bGlNT003Q1FFVWhxWkc0WDVaSzJqMmlVVWFTT1BrLU52Q3pWYUdZ?oc=5" target="_blank">Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation</a>  <font color="#6f6f6f">Nature</font>

Exploring the interplay between protein conformational changes and phosphorylation in a pancreatic cancer cell and stellate cell coculture system
PNASgeneral

Exploring the interplay between protein conformational changes and phosphorylation in a pancreatic cancer cell and stellate cell coculture system

<a href="https://news.google.com/rss/articles/CBMiYkFVX3lxTFBFSGxHLUdmblZzNXVQeGZ1NlhYY1lfNW92YVVWYTFCaDNhVmFtT3VQc0ZWRE1OZmNxQUhyN0w1QzY2M3o1VUJEVlRteHBfZzRhSmEtdC04MmpwTzAzb2dGRXJR?oc=5" target="_blank">Exploring the interplay between protein conformational changes and phosphorylation in a pancreatic cancer cell and stellate cell coculture system</a>  <font color="#6f6f6f">PNAS</font>

Solution-based biophysical characterization of conformation change in structure-switching aptamers
Cambridge University Press & Assessmentgeneral

Solution-based biophysical characterization of conformation change in structure-switching aptamers

<a href="https://news.google.com/rss/articles/CBMiswJBVV95cUxObW1Bc01SRW5FSEVsTFo3d0hES1I4TXJJdFl4TmwyNnRLcDJ2QlJkNllhdEtNNUlROWNraFdKdVNXaXE4SmhRa2VWaGxvcXgwV3ZWakE2Z2FGbXBOYkp1MmdpVnNQMnVwdkM5U3JNellpZnAwUHFtZnZCOXVaN2pRSWxNV2JpN0hmbGN1d3RlTXUzYWk4bzkxOW9uZEpyT2wwWEVYTkdaa256eU56c3BQVllUaFdKd0FyOXlhQllsaDJYLTVCZHJ3Q1Mwa3F4T1QwNDdZMUVtbFVCVUlyYjdPWmF6d1hQN2xkTklVblBoeGkta2poNkdPRmZrenlxNTlMLTZ3aFY1T193RkN5M1M1V1JzMUt0Q0swa2syUHFwSDk0Y2VwUGVXSmtSTWZmR3VhQ1p3?oc=5" target="_blank">Solution-based biophysical characterization of conformation change in structure-switching aptamers</a>  <font color="#6f6f6f">Cambridge University Press & Assessment</font>

HCN4 Mutation Causing Familial Inappropriate Sinus Tachycardia Leads to a Conformational Change Mimicking cAMP Binding and Induces Constitutive Channel Activity
American Heart Association Journalsgeneral

HCN4 Mutation Causing Familial Inappropriate Sinus Tachycardia Leads to a Conformational Change Mimicking cAMP Binding and Induces Constitutive Channel Activity

<a href="https://news.google.com/rss/articles/CBMibkFVX3lxTFBBUlB4LTBrN051MnJMelEyMUV2NGFRMjZuQ3NtVVhXMEFPMkE1M0dBNmRIZUY3WHNoZHpYVGVseF9KWl80LTZJRlFMMThmSWo2dmNaYmdhMmNaSkR6T01iNVZrVmtZMWhhTEdScU9B?oc=5" target="_blank">HCN4 Mutation Causing Familial Inappropriate Sinus Tachycardia Leads to a Conformational Change Mimicking cAMP Binding and Induces Constitutive Channel Activity</a>  <font color="#6f6f6f">American Heart Association Journals</font>

From disorder to icosahedral symmetry: How conformation-switching subunits enable RNA virus assembly
Science | AAASworld

From disorder to icosahedral symmetry: How conformation-switching subunits enable RNA virus assembly

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE10UTFybTJEVnE3c3hQcm8yVGRZUW9HbGgyZFMyZTNaZk8yT1NjSlBDcUY1dGJ0Mzl3dWRIUTV3UDVSSVZVaHVvVU5zTzFmUXRJcFZuc2hmM09MNEZIdVNJ?oc=5" target="_blank">From disorder to icosahedral symmetry: How conformation-switching subunits enable RNA virus assembly</a>  <font color="#6f6f6f">Science | AAAS</font>

Exploring Protein Conformational Changes Using a Large-Scale Biophysical Sampling Augmented Deep Learning Strategy
Wiley & Sonsgeneral

Exploring Protein Conformational Changes Using a Large-Scale Biophysical Sampling Augmented Deep Learning Strategy

<a href="https://news.google.com/rss/articles/CBMidkFVX3lxTE9ubXJkM0R4UVVuMGdzZzE2ZXhXMnl4YlVKQ3hhbUFBUUhvR3N1LWdWbm5WOFFfWmg1dS16XzMxUzJMYTVYRmg5dmdRY19jZmkyYWUySGVSTTFNRTk0VFZJNDk3Z2ctVGd3WkJRRkxJMW5tcXRWcGc?oc=5" target="_blank">Exploring Protein Conformational Changes Using a Large-Scale Biophysical Sampling Augmented Deep Learning Strategy</a>  <font color="#6f6f6f">Wiley & Sons</font>

Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space
Naturescience

Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1CaFdqT2FxNnRONGF5UEVWUHNMUjM0YW5TQ01vQjNBak1zZkotb2VmbnY0Qm1RRHlEb2p0QnkwTEp1OGZuM2JnTVg3NG10akE0VU1TTFhLZV8yTU9OQ0pr?oc=5" target="_blank">Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space</a>  <font color="#6f6f6f">Nature</font>

Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM
Natureworld

Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9BZVJ0NnBkMWNrQWxIYzZzLWxmWGViSERRSXF0N3NYLVViV3U0amo5VmstWnVhc0VDcm9mN0xwZUM1b1VOTHNNYjFCdW9nVFRIYUJ5Qk9QSDRmVHA3ZlZr?oc=5" target="_blank">Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM</a>  <font color="#6f6f6f">Nature</font>

Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome
Naturemarkets

Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE55Smp2LWttTVZEd3JaTlRnZVhpYUd4MGg4aGJUMURRVTVYWEpubkJxMVAtRmJzS08tWG9kVmlwa01nRFVuWHNmNDdVTnYzaE56N0ZEQTRORUVRWk1VT0xv?oc=5" target="_blank">Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome</a>  <font color="#6f6f6f">Nature</font>

Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain
Naturetech

Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1BS3c5cmJEeS1XUm9ELVBWbUVnWGNxV2xFX2xEZ2xEc0pGNFVEeEtoekVhZHE0blV5WmZBWkFUbzFlXzZ5RVVSLXFjdzBkTW5NQ3NfNmt4ZzRpckhaTlow?oc=5" target="_blank">Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain</a>  <font color="#6f6f6f">Nature</font>

Activation-Induced Conformational Changes of Dopamine D3 Receptor Promote the Formation of the Internal Water Channel
Naturegeneral

Activation-Induced Conformational Changes of Dopamine D3 Receptor Promote the Formation of the Internal Water Channel

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBHT3ZfSEZTVlVQYUJmNnE4YkpIRjJzU3ViNnNTZDhYT2cwNU56ZHJNYzdDM2dZRDVVc2FocHNpcVROUXR1dlRzcV9rQ0toS3RoRFBhTnA0YnVFSV9EVWZr?oc=5" target="_blank">Activation-Induced Conformational Changes of Dopamine D3 Receptor Promote the Formation of the Internal Water Channel</a>  <font color="#6f6f6f">Nature</font>

Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery
Naturegeneral

Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBWenZsXzJUbUh1RVFkbnVqbmJ4Y2pWT1YzY0xHQTJTZmhldHEyWVJpem9mVzE0QnNySlkwRlBqcjNaZW9zYUdJSzIydzl1bHdmNklqb3VndjlMajRNSFFn?oc=5" target="_blank">Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery</a>  <font color="#6f6f6f">Nature</font>

Human coronavirus HKU1 spike structures reveal the basis for sialoglycan specificity and carbohydrate-promoted conformational changes
Naturegeneral

Human coronavirus HKU1 spike structures reveal the basis for sialoglycan specificity and carbohydrate-promoted conformational changes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE54akZMOEVpZHZ2WVlNVFJwdU9hT0ZuaW1GQU9Cb2ljb29lbTJHdHFMZTlBckNkajJEcmh0c1pJZGhFT2xXajJLbk5vRTNTaDhua2Y4XzNyS3J1eHNKalNj?oc=5" target="_blank">Human coronavirus HKU1 spike structures reveal the basis for sialoglycan specificity and carbohydrate-promoted conformational changes</a>  <font color="#6f6f6f">Nature</font>

Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers
Naturegeneral

Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1iTXV2TERFTGxwdWo5LWdwd0hyOHJfVndLVGJ0NHNmUkRvNUlLeVJoWkNVUUY5d20zZ3dEUHZDQlJETFlJTkdocEhhZ3Jnc0U1MDQ5cEFVQmdCeUhUNEJR?oc=5" target="_blank">Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers</a>  <font color="#6f6f6f">Nature</font>

Atomic levers control pyranose ring conformations
PNASgeneral

Atomic levers control pyranose ring conformations

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE5adHQtS2p4SE1PcWxLUHpxNkNZc0gwYVMzUERISDJfVUdETjVhTXBBeHJvUHJNcllpWncwZDE5UkVKTGNQRWE3M05Cek1IZm1MVnJZa2FwcmJibmV4?oc=5" target="_blank">Atomic levers control pyranose ring conformations</a>  <font color="#6f6f6f">PNAS</font>

Accurately adjusted phenothiazine conformations: reversible conformation transformation at room temperature and self-recoverable stimuli-responsive phosphorescence
Naturegeneral

Accurately adjusted phenothiazine conformations: reversible conformation transformation at room temperature and self-recoverable stimuli-responsive phosphorescence

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBWdXNxQjJfbC05Z2l5XzVKTjhCYlpfSXRqeE5paEhWMXVQNVV4WDVaVU95M3A1STZkWXBHc2J4bzB3NmRvVTV6R3RiLWVaZzYtM1I2cU1SdENKaWhpLTZN?oc=5" target="_blank">Accurately adjusted phenothiazine conformations: reversible conformation transformation at room temperature and self-recoverable stimuli-responsive phosphorescence</a>  <font color="#6f6f6f">Nature</font>

EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution
Naturegeneral

EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE1rUXVtMFROSW1KNFY4eGQtRDBLZU9OMzdpX2RwQ1ptdnBNSW9LaWE4U2gtTWpsZEJRczhhenFJRWZKQUVxWllqX0NrTFh4NjF3YkZn?oc=5" target="_blank">EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution</a>  <font color="#6f6f6f">Nature</font>

Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association
Naturegeneral

Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1hV19yM3czWXpCNl96NU10U2hTYlMxVjFhRFRaLW9iQi1pcG5LVDU0WnV2QUtaaGJMaDF5VHdUQmNSVkxZNlRVNmtCekhUS2Y5VDdNVzBkYWxUTmh2RTJR?oc=5" target="_blank">Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association</a>  <font color="#6f6f6f">Nature</font>

Cryo-EM reveals a composite flavobicluster electron bifurcation site in the Bfu family member NfnABC
Naturegeneral

Cryo-EM reveals a composite flavobicluster electron bifurcation site in the Bfu family member NfnABC

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9VbEltY2lZTFYyNmlEblFlOTRndS1sSnhqTldxN3RSdlU1cFZITHNHa0E5U2RVNHktbXhoYUV0ckplQVZWNTJYQTVOTjYyMHZzQnNYRkRCenZOWmhEYzFV?oc=5" target="_blank">Cryo-EM reveals a composite flavobicluster electron bifurcation site in the Bfu family member NfnABC</a>  <font color="#6f6f6f">Nature</font>

signalling prompted by STIM1 conformational switch
Naturegeneral

signalling prompted by STIM1 conformational switch

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE9WSnZoTHExRjM4MVd6ekM3ZFZlQm10bzN5Z3lJTFY1UGFXUFM4OXVFXzVhSnJqbndNRjRWd01PSEduVEJiZ2taLVlqdzNwOF8wd0dmQQ?oc=5" target="_blank">signalling prompted by STIM1 conformational switch</a>  <font color="#6f6f6f">Nature</font>

Dynamic mechanostereochemical switching of a co-conformationally flexible [2]catenane controlled by specific ionic guests
Naturegeneral

Dynamic mechanostereochemical switching of a co-conformationally flexible [2]catenane controlled by specific ionic guests

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1YaWdmNnFMWHo4Uzg3U1hLVVI3SGNnRnQwYmFUMG9sWW5ZM1Q0a0o4bWhJcW0wS3JEYS1fOVllVExHSEdsc2JkbDB1ckJteXFhUWVJX2pjbENxdUxFNVRn?oc=5" target="_blank">Dynamic mechanostereochemical switching of a co-conformationally flexible [2]catenane controlled by specific ionic guests</a>  <font color="#6f6f6f">Nature</font>

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics
Naturetech

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBFRHFBZFVKUGxnQ0Z6WnA1U2hEMmlGLVhXQVQzQjhhRVFVazVrb1JmRU5QUV81WjBfRWJBeW1FRURBbnJSVEtBaUhWZG9FbmZ2UjJFWXZZWlpKTFZ5SUx3?oc=5" target="_blank">Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics</a>  <font color="#6f6f6f">Nature</font>

Computational study of terahertz-driven controllable molecular isomerization
Naturegeneral

Computational study of terahertz-driven controllable molecular isomerization

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5rUFNuTGtteXJkTlBsbkhtaEkzTzVBelZYdXN5ZWJ6LUJLc2pYem5faWxXc09Ua0w5bjhnZ0RVWlZLMmJ4NEdkQW1fSEhqek9ocWpSU3pWcjYzX3hLZVhv?oc=5" target="_blank">Computational study of terahertz-driven controllable molecular isomerization</a>  <font color="#6f6f6f">Nature</font>

Site-directed tryptophan fluorescence reveals two essential conformational changes in the Na+/H+ antiporter NhaA
PNASgeneral

Site-directed tryptophan fluorescence reveals two essential conformational changes in the Na+/H+ antiporter NhaA

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1tSHF1eXhUMmY0em84amF6MUlkdVpNVUkwN0RZb1VCVnR3Z3R5elExSUlsRWxsYzgwNUl5Y0xwQTRiNGdZdEZoV3VMUDRTNi01RE53OU9IdkJncnl4?oc=5" target="_blank">Site-directed tryptophan fluorescence reveals two essential conformational changes in the Na+/H+ antiporter NhaA</a>  <font color="#6f6f6f">PNAS</font>

Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing
Naturegeneral

Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9TanY0bU45RHh0bFZzaHgweFMzYnhIanJQWHRHckVpbjNTdTB4QTRFX2YwZnBzLWgzNS1SbmJ2ZnlPckRTMjNySG5aS2tDdjAyVlVnWWJVVDJFR01LcVBV?oc=5" target="_blank">Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing</a>  <font color="#6f6f6f">Nature</font>

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