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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Base editing-mediated per" (30 stories)

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CRISPR-free RNA base editing mediated PTC-readthrough restores hearing in mice with Otof nonsense mutation
Lead StoryNaturegeneral
Dec 6, 2025

CRISPR-free RNA base editing mediated PTC-readthrough restores hearing in mice with Otof nonsense mutation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9pN2hyTmR4QkFocTV2U0M1SzNZUmlOeGFBX1FqZzlwd3NrOHJfWUhSTGpRNHlVM3VxdGtGZ3JSODVnUjR1SDJQY2RFd2FlTUd5YWR4UGgyN2k2LUZ3TTBV?oc=5" target="_blank">CRISPR-free RNA base editing mediated PTC-readthrough restores hearing in mice with Otof nonsense mutation</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Base editing-mediated per"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
Base editing of β0-thalassemia mutations as a therapeutic strategy for severe β-hemoglobinopathies
Science | AAASgeneral

Base editing of β0-thalassemia mutations as a therapeutic strategy for severe β-hemoglobinopathies

<a href="https://news.google.com/rss/articles/CBMiZ0FVX3lxTE9ESlhnTGpxY2FCQTVrSlVZVWZIazdEaFBvLUpKMWdHb185MmFraEF5eS1mQVludURTYkZGdjRDblpSUjJwX3pBdlRjbm4xSVIyRmsxcHhNaHFIbUpRX0U0ZEhXMU1RamM?oc=5" target="_blank">Base editing of β0-thalassemia mutations as a therapeutic strategy for severe β-hemoglobinopathies</a>  <font color="#6f6f6f">Science | AAAS</font>

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An Agrobacterium -mediated base editing approach generates transgene-free edited banana
Wiley & Sonsgeneral

An Agrobacterium -mediated base editing approach generates transgene-free edited banana

<a href="https://news.google.com/rss/articles/CBMiaEFVX3lxTE9FeHNYR01iaGVlVWtMR08wQ3pmMkdzTXVpTHYyd2tOSHBqcGlrSk0taklnaS02M2RUSFRBb1lDTFEtVFR4NTdMNFhXYnBZakVjVlpaZHA2ejF5ejgtRmUwenRrdHFUWXJ6?oc=5" target="_blank">An Agrobacterium -mediated base editing approach generates transgene-free edited banana</a>  <font color="#6f6f6f">Wiley & Sons</font>

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Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions
Naturegeneral

Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBQakF0XzJGVG9BNURLekdGTHJ0YThieXZGaUd3WW1FQjI4bnQ5Q3VBUTFqZFp3NHJPVjNnLURHblJXQTkyNFJkQUE1TnMzS0tNbnAxTXdyWVZkTVZ2R2NJ?oc=5" target="_blank">Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions</a>  <font color="#6f6f6f">Nature</font>

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Harnessing accurate mitochondrial DNA base editing mediated by DdCBEs in a predictable manner
Frontiersgeneral

Harnessing accurate mitochondrial DNA base editing mediated by DdCBEs in a predictable manner

<a href="https://news.google.com/rss/articles/CBMirwFBVV95cUxONXBfU0UyUEl6N2luSEdMWUEtZDZnbjduRFY0dVlEOVB5Y3NUbFJNOVJuOENSbnJMNE9YNkdrQVpBekVpUjRMc2ZiaDEtSmVkb1B3ZVpwREdpMVJORW51c1VTOGQ2RW95VGw2YzVKOGxtc3RXcWwtbnU2U1AzTFlIN2p2b0hKMG5GMnVEVVlYS2pmcEQyMGFXdGNpNlpfVldkbGphMm92QTBRYlJ6T0lJ?oc=5" target="_blank">Harnessing accurate mitochondrial DNA base editing mediated by DdCBEs in a predictable manner</a>  <font color="#6f6f6f">Frontiers</font>

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Prime editing-installed suppressor tRNAs for disease-agnostic genome editing
Naturegeneral

Prime editing-installed suppressor tRNAs for disease-agnostic genome editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1QWngxUGpQSEpxcjJ1bE4xMHNkY2FyU0R0SGdrNVZRV0xuRUc5dWdlZ1k0b2pGRUEtT2ZGTUM1RVFjcXNYdGVvR2M5LVI3alRWdWpkSFVyc3RpNFpPT2xz?oc=5" target="_blank">Prime editing-installed suppressor tRNAs for disease-agnostic genome editing</a>  <font color="#6f6f6f">Nature</font>

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Extracellular vesicle–mediated gene editing for the treatment of nonsyndromic progressive hearing loss in adult mice
Science | AAASgeneral

Extracellular vesicle–mediated gene editing for the treatment of nonsyndromic progressive hearing loss in adult mice

<a href="https://news.google.com/rss/articles/CBMiZ0FVX3lxTE05MnNEY2RDd3BzOGRpYkRFcEFzN01OWFV0TXZISWNjVW9jWWNCTGt5clk5SmZqQWMxYll6ZjRxRDBKdk1naFJNaV9uOFNyR0xHMTVfc0J4cXpKTnozaXdybjF1TGhFcGM?oc=5" target="_blank">Extracellular vesicle–mediated gene editing for the treatment of nonsyndromic progressive hearing loss in adult mice</a>  <font color="#6f6f6f">Science | AAAS</font>

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Adenine base editing-mediated exon skipping restores dystrophin in humanized Duchenne mouse model
Naturegeneral

Adenine base editing-mediated exon skipping restores dystrophin in humanized Duchenne mouse model

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE92OEZOSkpTT05iSld4OHFMMjR0em1rN2RZcnR5RERpdVYtNFhsaEJfZHZrQUlxZHNTN2l3OG1HN2FkMG9TODJtTXZxRFc1UWhoMUhJLVZYVUl1Yzl1NGNv?oc=5" target="_blank">Adenine base editing-mediated exon skipping restores dystrophin in humanized Duchenne mouse model</a>  <font color="#6f6f6f">Nature</font>

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Base-editing-mediated dissection of a γ-globin cis -regulatory element for the therapeutic reactivation of fetal hemoglobin expression
Naturegeneral

Base-editing-mediated dissection of a γ-globin cis -regulatory element for the therapeutic reactivation of fetal hemoglobin expression

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE93YnVabUpxb0ZIeUFJMmxrRjV1YmdVTlFKUzMxcy1nMHVqbzA3d3N1Z2NxclFlbTY3cjJ2a1ZZRkwtTjMzbk44a3JPY0M1Uk5pVmdpSjFVSUJfY0xMdGhB?oc=5" target="_blank">Base-editing-mediated dissection of a γ-globin cis -regulatory element for the therapeutic reactivation of fetal hemoglobin expression</a>  <font color="#6f6f6f">Nature</font>

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Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation
Naturegeneral

Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE50NjAyaC1MdTdCOXN2NmdyMmhBdHpnc1JIb0t4RXJaVHNpdGF2emdabjZBa3dlRE5VYWhHV25VWnJKcW1mYmJoc3RFRXU1M2ZZZlVCUDFGakhNU083LTlF?oc=5" target="_blank">Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation</a>  <font color="#6f6f6f">Nature</font>

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Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology
Naturetech

Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE45N3ZDRThWR2JEUmx4eUJnSS1IYW1CY2NNZnJyeURrY29pRVUyQ3RTMnNnRExPdnc2M0VUc2NzaVhoTllrOXRQbzZqS251c3l1LURhZWJINlV4amVJcmxR?oc=5" target="_blank">Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology</a>  <font color="#6f6f6f">Nature</font>

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In vivo base editing rescues ADPKD in a humanized mouse model
Naturegeneral

In vivo base editing rescues ADPKD in a humanized mouse model

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9lWHFNZkMzckpqYlNROG0takcxbnNVeHk2S2dOQmF6Ti0wci1uTEJaOERYM2tabmcxdlF5ZlY5cGtoMUNWN09vUWpFUU9TSGQ5T1VoME1XcVRNa1J3TVdz?oc=5" target="_blank">In vivo base editing rescues ADPKD in a humanized mouse model</a>  <font color="#6f6f6f">Nature</font>

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Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins
Naturegeneral

Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1IekFGUTVkMnFja0hnV3E5dnBoS2pfLTJWT2JIUS1kR21PckJQbTJDWm9tUVVmd1NOeUQwMHExRExTeHkweTJBYkJhOUl1eVFPRlkxaWZiZEtySWtjRWpZ?oc=5" target="_blank">Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins</a>  <font color="#6f6f6f">Nature</font>

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CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells
Naturegeneral

CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE96Z05CelNlMzlnYXJFcWhXRUdRMi04MGY5SXZJUkFJSVFUNG8tZDJxX3h5NzItM3UxOGNDNEgxdXpvMXlMTUhrdTFsOElFZ0ctSlhkNlZ2QXFSUURWZmVF?oc=5" target="_blank">CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells</a>  <font color="#6f6f6f">Nature</font>

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Precision multiplexed base editing in human cells using Cas12a-derived base editors
Naturegeneral

Precision multiplexed base editing in human cells using Cas12a-derived base editors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9lMkRvV1NCdGgzQlFLSnlEY2hmZC1JemdlTUF0eWhjZDVLdVRVMlhzb1N4S01fbzJaaERFT3RJNVNReEF5a2dqak93MjEwMTQtelppYVJWVW8wWGtMLU84?oc=5" target="_blank">Precision multiplexed base editing in human cells using Cas12a-derived base editors</a>  <font color="#6f6f6f">Nature</font>

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QBEmax is a sequence-permuted and internally protected base editor
Naturegeneral

QBEmax is a sequence-permuted and internally protected base editor

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8xZTlNLUMydmhpdnhtWEJxNG84UzZvOUprT0E0OG1nZVZrUmdSc1pBcEl0QnEtbndSM2xYMFplZ0swX2pXT3FpcVJ3MkcwcFVfVHh6S1JpTDRraldFOXJF?oc=5" target="_blank">QBEmax is a sequence-permuted and internally protected base editor</a>  <font color="#6f6f6f">Nature</font>

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SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping
Naturegeneral

SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8zanJDdDAzNW9JcFZpdURRc0dpSFpZX0hLaDhfeER6NmdzMEFoc1A1TXl3VVY1YnNqV1BhVUhIc093T1pGendER1VfcmZuaGxpX0hLdXUyMDJSNVo1QmJV?oc=5" target="_blank">SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping</a>  <font color="#6f6f6f">Nature</font>

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Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors
Naturegeneral

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1Xa2tJYXhUV0JSQ0RGYmktcVhmeEJSX2s2MUplT2FFeTRENUVOczh2LUd0dTNvTnVXNUNLUWxLODJQWk1kN0YxNEVIQnMyWXBHWnJwTmoyRkdlUXd4VUNZ?oc=5" target="_blank">Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors</a>  <font color="#6f6f6f">Nature</font>

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In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorder
Natureworld

In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorder

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE05SlVoZmxpa0hfaURUWHkxd3FlMUIxRENmVDcza0pDa3BkbDNSbXlfR01feHdkRE1adkYwblpkVGVydmluSHZvbjBmX01Ndi1iUnZHZVNCSGc0QVV6N2hF?oc=5" target="_blank">In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorder</a>  <font color="#6f6f6f">Nature</font>

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Prime editor-mediated correction of a pathogenic mutation in purebred dogs
Naturegeneral

Prime editor-mediated correction of a pathogenic mutation in purebred dogs

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1OVDh2QUxBSE5LeWU4MHVkSU9rVmN6eUp1S1NiTDVDaWhjTmd2eWhMWFdWS2FtOHFqck5QZHpramRlWFpPaXZVeHJFRGpmeS1mUENTd09TZGZUVW1fbjZF?oc=5" target="_blank">Prime editor-mediated correction of a pathogenic mutation in purebred dogs</a>  <font color="#6f6f6f">Nature</font>

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Engineered ADARs enable precision A-to-G base editing of DNA
Naturegeneral

Engineered ADARs enable precision A-to-G base editing of DNA

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA2ZjdBcTZkYXRHNk8wTWt2TTNWTi1qMXlsRVlSUHFpa0pndERSZnJRVzdRTm5RWWN3cUNMZkdpNEFicndiaGI1dmp2Qk5Ga1N3T3ozeERaYXZQMGhYcGZJ?oc=5" target="_blank">Engineered ADARs enable precision A-to-G base editing of DNA</a>  <font color="#6f6f6f">Nature</font>

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Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9
Naturetech

Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBDMTd2MkZqM2h2NFdzcGRvWXBROFRJNkZEY0xsNllyLWZfRkt6eHIxNElhdjR2V21YYTBhaVlqUFpscDRMR05EU01DdGJ6SFRPWXBMSUtJZTAwNHN2V0k4?oc=5" target="_blank">Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9</a>  <font color="#6f6f6f">Nature</font>

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Cytosine base editors with increased PAM and deaminase motif flexibility for gene editing in zebrafish
Naturegeneral

Cytosine base editors with increased PAM and deaminase motif flexibility for gene editing in zebrafish

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9aTW0yMTg1bHBkT2w4d201ZVk4dm5vQi1PSnVEWnc3LXhhNHlWYnBNY0JtZG9vU1p1aEZYWGRHLUZaNVl5QmhaZnRLSFpvZEVpVUJjZ1lBMWFRNXRwQkJn?oc=5" target="_blank">Cytosine base editors with increased PAM and deaminase motif flexibility for gene editing in zebrafish</a>  <font color="#6f6f6f">Nature</font>

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Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors
Naturegeneral

Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE91VlR3MjNUTGJfM2VkNllyNWw1UUFDdVpHb1ZGMnJObzh6RzZWYkpYVDFPNVFBLWJDOFFRQlVKLXh2Zm5BeDVHenVjdXJaX0pRYTAwekxKMjBIanFkZVln?oc=5" target="_blank">Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors</a>  <font color="#6f6f6f">Nature</font>

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AI-designed OpenCRISPR-1 performs robust knockout, base editing, and prime editing in rice
Wiley & Sonstech

AI-designed OpenCRISPR-1 performs robust knockout, base editing, and prime editing in rice

<a href="https://news.google.com/rss/articles/CBMiaEFVX3lxTE40ajJkOExrdXppeWhTeVdVV2xOZVdGelJHUWhjVE1JQ29HU2t3clVOdXVOVFVkVUVWb2JueGJyU0VjekROQ1hmSGhxZUNWOXJxdzRKS1J3RFhBQ2F2VEdDeFNBckp1R1BK?oc=5" target="_blank">AI-designed OpenCRISPR-1 performs robust knockout, base editing, and prime editing in rice</a>  <font color="#6f6f6f">Wiley & Sons</font>

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Engineered Sdd7 cytosine base editors with enhanced specificity
Naturegeneral

Engineered Sdd7 cytosine base editors with enhanced specificity

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB1WmZ6Rk55dC1xclJ5bnJ3WHQyTV9RTXUtcU9fMVVuS1YzNlQ1M254OTBOTTVxeElIMU5ZYlBPbnBrWUpxa2MyYk94YXhBZXhlOXdfNlhCUDM4Qm5MQU1Z?oc=5" target="_blank">Engineered Sdd7 cytosine base editors with enhanced specificity</a>  <font color="#6f6f6f">Nature</font>

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Expanding the CRISPR base editing toolbox in Drosophila melanogaster
Naturegeneral

Expanding the CRISPR base editing toolbox in Drosophila melanogaster

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE11VDZtb0tBRWEyQ3d0ZHVMRXZ5eUFTU05YWDVvcGdORGRTWVhvdFBRaTdyYnF5U29uRVR5SFFTUm4xUWEtbnIxWldUZlFnNVpKeW9QcU1UVFl1NWR5TXk4?oc=5" target="_blank">Expanding the CRISPR base editing toolbox in Drosophila melanogaster</a>  <font color="#6f6f6f">Nature</font>

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Cytosine base editing systems with minimized off-target effect and molecular size
Naturegeneral

Cytosine base editing systems with minimized off-target effect and molecular size

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5DSGNxQTcxTXFNU1VYQm5ta1FCTC1BTmFZNHQ2eUMxeXJRR0xFNm95TzZ1Q3lmRVE4dHM5VHVITjkxNV93bW1sV0NQTVFoc2JwVHdsa1h1RUt1T3lmMkRJ?oc=5" target="_blank">Cytosine base editing systems with minimized off-target effect and molecular size</a>  <font color="#6f6f6f">Nature</font>

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Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations
Naturegeneral

Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA4NFJwRzlhNm1SOUdhaTQ2LUZvYXlpUUs0aEVncnlNM2NVWVUxR0U4cGFKN2RMRVdBVGlrYnl5UFZ5VmtHY3FFQUp3N3BzMWVSb2lhSGtwR3JGNHh2UDU4?oc=5" target="_blank">Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations</a>  <font color="#6f6f6f">Nature</font>

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CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders
Frontiersgeneral

CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders

<a href="https://news.google.com/rss/articles/CBMilwFBVV95cUxQb2pUWWZURGpiaS1EWm5nWnU3OENod09QMnlxOGJFdDlhUHM3X1dNeFV1el9qM1RsNVpGMHBpNEJROTBldjRTbFVTQ25rVkl4eDBJdHZIQ0oyd3Yzb09abVRZb2k1UFRyS2JzTTY2bkFtb0JBTmNhdFR6RC1wclU5TnhwYi00M2dpUERUYVdvSUM4WjVxNG9F?oc=5" target="_blank">CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders</a>  <font color="#6f6f6f">Frontiers</font>

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