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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Base editing enables off-" (30 stories)

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Non-genotoxic transplantation and in vivo selection through epitope editing
Lead StoryNaturepolitics
Jul 8

Non-genotoxic transplantation and in vivo selection through epitope editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBjcTNoMVNneDktNWwwLUNvZFE4Vkc3NFRFR0tyc0Q5ZXJpXzFyRE95cXVjVmR1ZWV6RktyTEU1QXAyZTIxWmNlZWFoOFJHRENrMnZkVlVZMUg2Sy1VQ3hZ?oc=5" target="_blank">Non-genotoxic transplantation and in vivo selection through epitope editing</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Base editing enables off-"

Updated every 3 minutes via FreeNewsApi, GNews, Currents API & Google News

29 stories displayed
Broken String Biosciences launches BaseMap ABE to enable genome-wide off-target characterization in base editing therapeutic development
News-Medicalscience

Broken String Biosciences launches BaseMap ABE to enable genome-wide off-target characterization in base editing therapeutic development

<a href="https://news.google.com/rss/articles/CBMikgJBVV95cUxQNktKcC1kQjVyLWsyYUVBVGVVTDgycm5BZXJXQVJiOXlLaFBZU0ZRYWt3ZTFqZFpPOTNCcTItbG5Wamw4azdjajF1dExHMXVDOXhZMWs2cFYzQ1JyMjlmT1RYZDFmMlRUYVN6THdZZ0Jtb1hMdVdmdDNydmEyOElCeXlnQzh3cndnRnFxeHV1ckNGOGpDYUFBaTMxSGNWUC13ZXNZeEt5V0pzZGRlRmpCMnRwN0JpUTZKQWxSZV9HdDNiSVZFa05hTkVhU1F5dWUwMURSdURXQU41YVUtQzZLSXM2V3hqdFpudExvb3BGTWlEQzNMOE04dWNubWE3b19jUk1oRE10NUl5cGIzUURFNGRn?oc=5" target="_blank">Broken String Biosciences launches BaseMap ABE to enable genome-wide off-target characterization in base editing therapeutic development</a>  <font color="#6f6f6f">News-Medical</font>

BaseMap ABE Launched for Off-Target Characterization in Base Editing Therapeutic Development
Genetic Engineering and Biotechnology Newsworld

BaseMap ABE Launched for Off-Target Characterization in Base Editing Therapeutic Development

<a href="https://news.google.com/rss/articles/CBMi2gFBVV95cUxOZGc0UTkxSWFvZFJJd05PZ0hCR0FHaVM3YXdDX2tjR2dfYTBfeEdWeUEtNF9YWXRDNWR0SkZqX1FFUmdXOGVTYWROeC14WkFUSEwya2pCbEpaU3NzYXVUSmJBN3VxSXJNbUljbm13RFlSOU9xLTBGNHR3blRXR1YxUFNiZEFjWEIxUy04WVJDc2EwdTRZR0pzS2hVRjBKU190UzFDb1RvUW9xZW81dURQYWtNSWJwNklXM0JSS2NmeFlyM0sxX1N6bmwtdURVaVNRUnVPT3lHb3hMZw?oc=5" target="_blank">BaseMap ABE Launched for Off-Target Characterization in Base Editing Therapeutic Development</a>  <font color="#6f6f6f">Genetic Engineering and Biotechnology News</font>

UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems
Natureworld

UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ZaTF4TmdpWnk1TjhvZUtVQnpkRExmVEF3YkFURkJ5ZU9zRjhoZDlZNmVFQVRwbW0yWEx6VUlPLTl6Qm5SNjlsZXhuQ2dSdlV4dkdHN0tmanJKZG1fM3Zn?oc=5" target="_blank">UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems</a>  <font color="#6f6f6f">Nature</font>

AlphaFold3 contact modeling enables precise DNA base editing
Bioengineer.orggeneral

AlphaFold3 contact modeling enables precise DNA base editing

<a href="https://news.google.com/rss/articles/CBMijgFBVV95cUxNNDZYU0JlWUVyekpVdDAtb1BtcVctcDZwSm0xRXhPdU5nc0JCOXhETmMxN3ItR1VCZFFsRmJHeGhmc2RFbkRHVVFoZk5wNHliTjBpQlBZa2pMMTkwM3N6UkN1TXNlYWNNMzlZaFZadFEyZllUeXhuTkg4OVNHeHdNVTh1d2hDOXp2QUNJWXlR?oc=5" target="_blank">AlphaFold3 contact modeling enables precise DNA base editing</a>  <font color="#6f6f6f">Bioengineer.org</font>

SNU professor Sangwoo Seo’s research team develops next-generation CRISPR biocontainment technology for controlling microbial survival without DNA cleavage
EurekAlert! Science News Releasestech

SNU professor Sangwoo Seo’s research team develops next-generation CRISPR biocontainment technology for controlling microbial survival without DNA cleavage

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTFBfQ1o1eG16OXUzaTBvTnhvcU9GeGE0TnNhcEZ0Q2U4T2xBR1RNaFBxMV94SUdobFFKSkUtaGdlajdMMHVOMWg5bzlBVUZKbHNfUlJPTjJ4QWZKYmpX?oc=5" target="_blank">SNU professor Sangwoo Seo’s research team develops next-generation CRISPR biocontainment technology for controlling microbial survival without DNA cleavage</a>  <font color="#6f6f6f">EurekAlert! Science News Releases</font>

Engineered ADARs enable precision A-to-G base editing of DNA
Naturegeneral

Engineered ADARs enable precision A-to-G base editing of DNA

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA2ZjdBcTZkYXRHNk8wTWt2TTNWTi1qMXlsRVlSUHFpa0pndERSZnJRVzdRTm5RWWN3cUNMZkdpNEFicndiaGI1dmp2Qk5Ga1N3T3ozeERaYXZQMGhYcGZJ?oc=5" target="_blank">Engineered ADARs enable precision A-to-G base editing of DNA</a>  <font color="#6f6f6f">Nature</font>

Base Edited CAR Ts Show Off-The-Shelf Promise for T-Cell Leukemia
Inside Precision Medicinegeneral

Base Edited CAR Ts Show Off-The-Shelf Promise for T-Cell Leukemia

<a href="https://news.google.com/rss/articles/CBMizAFBVV95cUxQNE5rZ1ZiZWlIV2JMY2hCNzVlNURkZzg5YkdtN2V3RTZvR2xZal9DRDl3TGtTdm1EYVpOWkh2dWdoN0VfdmxtbG9iTy04YktDdVkxNl9SYkR4bXNHYWhPQkQxcy1oYU5GX1hEcG5teGo1cUp0SURUdW41djdTQ0M3dkIxejNnbE9UUVJKcm1WeXlpV0pyZWlYdTh0UUNXRkRlS1E4UDlLZjBzZ2NINDJ2Z0JTTFg4QWNsRVhLU01TcncwSVdnMnBnODV3YS0?oc=5" target="_blank">Base Edited CAR Ts Show Off-The-Shelf Promise for T-Cell Leukemia</a>  <font color="#6f6f6f">Inside Precision Medicine</font>

A better way to detect off-target genome changes from base editors
Phys.orggeneral

A better way to detect off-target genome changes from base editors

<a href="https://news.google.com/rss/articles/CBMiZEFVX3lxTE14aUkxV19pRkx6MEEzNFRpRERmcVdaMVd3azktXzF0NjRhUEo0UEVUWlJUWUU5TUJvaDFpRDJfQ29uY3Nwa1lZRV8zZ2ZoOXc1OTNrVnRMY0FhT3dOSWxiLWJ3aUQ?oc=5" target="_blank">A better way to detect off-target genome changes from base editors</a>  <font color="#6f6f6f">Phys.org</font>

Base editing enables off-the-shelf CAR T cells for leukemia
Naturegeneral

Base editing enables off-the-shelf CAR T cells for leukemia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5fbTFHRnV6SFBvQlQtWG0ycldkZVQ2LTZXOVU3QkpSb1ZPeFBIREQxTU85M0hLZlJsZUlTNkxzWE5UWU5YUVJmaEdWWW9lMUN6R0NQenFja2NvNkRiNzVv?oc=5" target="_blank">Base editing enables off-the-shelf CAR T cells for leukemia</a>  <font color="#6f6f6f">Nature</font>

Target-stabilized base editors enable robust high-fidelity RNA editing
Naturegeneral

Target-stabilized base editors enable robust high-fidelity RNA editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1VU0tuR1ZjT0xIV3lkOTg1S2x6b3FvN0NSb2l0WHd3V0pUZWFpVjFyRGh3REl1TEpqd2h2VG5zU2lpWHBwTWE1QmdWZzFWSS1uN1BhTE1Ud0d6dzE0Wjg4?oc=5" target="_blank">Target-stabilized base editors enable robust high-fidelity RNA editing</a>  <font color="#6f6f6f">Nature</font>

Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions
Naturegeneral

Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBQakF0XzJGVG9BNURLekdGTHJ0YThieXZGaUd3WW1FQjI4bnQ5Q3VBUTFqZFp3NHJPVjNnLURHblJXQTkyNFJkQUE1TnMzS0tNbnAxTXdyWVZkTVZ2R2NJ?oc=5" target="_blank">Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions</a>  <font color="#6f6f6f">Nature</font>

Engineered base editors with reduced bystander editing through directed evolution
Naturegeneral

Engineered base editors with reduced bystander editing through directed evolution

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBUT2J4dGhSWWRNUEJuWDdhWHJjNldIVko1ZzlNaS1MUjRPaFM2R3VVSjBYNXQyYkxmZTVmMy1FMDRVdkdrSy1Wa01IZi1sSEx6cGtDUEQ5dW1hZUV3Y0dV?oc=5" target="_blank">Engineered base editors with reduced bystander editing through directed evolution</a>  <font color="#6f6f6f">Nature</font>

Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity using CHANGE-seq-BE
Natureworld

Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity using CHANGE-seq-BE

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA2dG5GOGNKbWlwWlU1WlVHcEVLbUE5TDZTbmdGTTRVQmpqMkVHeVF6UTNIMElpU09odTd2Vm95ekpvZWRZRHZwd3ZHV1FZUXk2OVNvR25lOGVZaVpjYTMw?oc=5" target="_blank">Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity using CHANGE-seq-BE</a>  <font color="#6f6f6f">Nature</font>

High-efficiency TadA cytosine base editors for precise modelling of human disease variants
Naturegeneral

High-efficiency TadA cytosine base editors for precise modelling of human disease variants

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE41eTFUeDVkQlNzeE91emZESVBrUXVNaWdsc3I5WXNpS284TmJYUGRHTzFWWGd4ZWl0MUlET2JkZGxNejFycVVKSDhHZ2E5R2RWNVNJZFZ3WHpta1B1Unpn?oc=5" target="_blank">High-efficiency TadA cytosine base editors for precise modelling of human disease variants</a>  <font color="#6f6f6f">Nature</font>

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models | Scientific Reports
Naturegeneral

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models | Scientific Reports

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5NZGxvLXV4cldSNUQ5aEVhWDFCVDhJbVU1bmdsVTRVcmlIYmNGT2hWcnBhNmZUSTBNTjVSVHJ5M2ZEakRGQzhHbWpVM3pXNnZPenR1M0o1WDQ1NUhmRTdJ?oc=5" target="_blank">ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models | Scientific Reports</a>  <font color="#6f6f6f">Nature</font>

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
Naturegeneral

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBnQTlQZF9Ec2NnZVNOQ1F4TEd3RWdkX1NzWGhHNWF4Q0NiWFNGdGtFLS1sSk9JclRJRFliSU5UbWI0OXR1eHZwbjd3MW8xTnhHUktKRDRXeHMyekJDMUVB?oc=5" target="_blank">Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy</a>  <font color="#6f6f6f">Nature</font>

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces
Naturegeneral

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBpYjA2N2ZGVGt0Z3NzVVAyYm9Da2lzejJJdnI0SHduLWZ6NWF0WGZhb01Dbm1pTld3ZTdCUGx6SWtUMHl2RXBYUHNBaFR3c3NkbzVWVEloeHN4UUJWRHh3?oc=5" target="_blank">Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces</a>  <font color="#6f6f6f">Nature</font>

Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia
The New England Journal of Medicinegeneral

Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTFBPMjRrNUotY0s2UjdmeC1tUlcwbElPaGxqWDZEYzR4SXpfUDVaZFVoMDhJSjlkUzZyY2dnWDNNQmpVbVRVZEhSX3gyNVhDWmxFdE4tRDlyYzF1TkE1Tk9pVg?oc=5" target="_blank">Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia</a>  <font color="#6f6f6f">The New England Journal of Medicine</font>

Gene-edited CAR-T cells erase aggressive T-cell leukemia
ScienceDailygeneral

Gene-edited CAR-T cells erase aggressive T-cell leukemia

<a href="https://news.google.com/rss/articles/CBMib0FVX3lxTFBPMEt2ZGdwX3puUjZ6R0Q0YnRuR3M3UUU0bVBTNkMxVGlDcENpdkp1TFdiNzhCWktfc3lZbnFEU1RRaG5ha004c01BWE14X2wydllqTmRVNjdqSmMxd213ZzAteGlVbnVaN2NoZzNPdw?oc=5" target="_blank">Gene-edited CAR-T cells erase aggressive T-cell leukemia</a>  <font color="#6f6f6f">ScienceDaily</font>

Cytosine base editing systems with minimized off-target effect and molecular size
Naturegeneral

Cytosine base editing systems with minimized off-target effect and molecular size

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5DSGNxQTcxTXFNU1VYQm5ta1FCTC1BTmFZNHQ2eUMxeXJRR0xFNm95TzZ1Q3lmRVE4dHM5VHVITjkxNV93bW1sV0NQTVFoc2JwVHdsa1h1RUt1T3lmMkRJ?oc=5" target="_blank">Cytosine base editing systems with minimized off-target effect and molecular size</a>  <font color="#6f6f6f">Nature</font>

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia
Natureworld

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9kSnlQRV9sQk1YckxsMjYwSlVGSWpzM1RqQ0ZvM3doMDQyalBweWwzRVRwQkQwaEpSRTIxRXJBQVdCQjRVMlplSWhuMEMzdmR4aExKdFZrcFducDkzSlNn?oc=5" target="_blank">Epitope editing enables targeted immunotherapy of acute myeloid leukaemia</a>  <font color="#6f6f6f">Nature</font>

CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders
Frontiersgeneral

CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders

<a href="https://news.google.com/rss/articles/CBMilwFBVV95cUxQb2pUWWZURGpiaS1EWm5nWnU3OENod09QMnlxOGJFdDlhUHM3X1dNeFV1el9qM1RsNVpGMHBpNEJROTBldjRTbFVTQ25rVkl4eDBJdHZIQ0oyd3Yzb09abVRZb2k1UFRyS2JzTTY2bkFtb0JBTmNhdFR6RC1wclU5TnhwYi00M2dpUERUYVdvSUM4WjVxNG9F?oc=5" target="_blank">CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders</a>  <font color="#6f6f6f">Frontiers</font>

Engineered deaminases enable precise RNA base editing
CRISPR Medicine Newsgeneral

Engineered deaminases enable precise RNA base editing

<a href="https://news.google.com/rss/articles/CBMilAFBVV95cUxNdERnSDdQSzh2TXZGajBmb0tnbzVUNW9MTDdZN01nQWpUbHJMSTBLc3ZLanBENzRMT0NyTjVaMi1ueE1ZanU4MXJXbkxkX0tha2VjWjdiZHpuTklVUnNudmltbk01VHJFM096bHhRUUJlNG84RUtvSXZXMnVGdEJ6ckRCZjhnT3dvS2JHQ2Y1OFEwZkQ2?oc=5" target="_blank">Engineered deaminases enable precise RNA base editing</a>  <font color="#6f6f6f">CRISPR Medicine News</font>

Evolved cytidine and adenine base editors with high precision and minimized off-target activity by a continuous directed evolution system in mammalian cells
Naturegeneral

Evolved cytidine and adenine base editors with high precision and minimized off-target activity by a continuous directed evolution system in mammalian cells

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1mTkxOXzFHVWw1SnZkRWp0RldZcnlKU2pWLXB3ZWtyTlZXSXpMMGxoUHZEaEtrZVhWc3NIZTEwa2ZlZ1NVanFXU3Q3NklkbG4tbnBfbW1vTTJGQlFXNmo4?oc=5" target="_blank">Evolved cytidine and adenine base editors with high precision and minimized off-target activity by a continuous directed evolution system in mammalian cells</a>  <font color="#6f6f6f">Nature</font>

What are gene editing therapies? CRISPR, base editing, and prime editing in modern genetic medicine
Drug Discovery Newsgeneral

What are gene editing therapies? CRISPR, base editing, and prime editing in modern genetic medicine

<a href="https://news.google.com/rss/articles/CBMi0gFBVV95cUxOdTNGM0hLTEtIWDN2V0tlaWVJbnhkS2ZGTzJjNHI4MngxQ1hwT2ZwU25YandUMXVDc00ybUV1VGF3ZzAxWjhFdHVETGc4ZFNrdE1LUTloS3NTNVFYX2FIMHdiZ3QwSjBBX01aYVkxZmZEcDhXS1JnbDRxS25HQmhyVmlBNVNIYTNGYWFJZ2RFa0cxMVA2Y0N2Y2FFWHVIOUpBVC1EWG1ZLTFpS3FlbTkxdEVuelAyYVhCMDEwUVg3ZVlwVUZrUXpIX3VjS3RnOTlObEE?oc=5" target="_blank">What are gene editing therapies? CRISPR, base editing, and prime editing in modern genetic medicine</a>  <font color="#6f6f6f">Drug Discovery News</font>

Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine
Wiley Online Librarygeneral

Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine

<a href="https://news.google.com/rss/articles/CBMia0FVX3lxTE1RU2tfYUE4THdlek8zZk5iTU16T2JVVWZCNWt4elBqU1FqTkRRZ2hSTExFNUZub3lyME00MFBWNnZUMTFnZzRFdXpKMHhlVFRzZUxGWm1KVGNDb2ltYjdoTlltcXdxdXo1bG0w?oc=5" target="_blank">Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine</a>  <font color="#6f6f6f">Wiley Online Library</font>

Precision multiplexed base editing in human cells using Cas12a-derived base editors
Naturegeneral

Precision multiplexed base editing in human cells using Cas12a-derived base editors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9lMkRvV1NCdGgzQlFLSnlEY2hmZC1JemdlTUF0eWhjZDVLdVRVMlhzb1N4S01fbzJaaERFT3RJNVNReEF5a2dqak93MjEwMTQtelppYVJWVW8wWGtMLU84?oc=5" target="_blank">Precision multiplexed base editing in human cells using Cas12a-derived base editors</a>  <font color="#6f6f6f">Nature</font>

High-diversity base mutagenesis via simultaneous adenine, cytosine and guanine editing
Naturegeneral

High-diversity base mutagenesis via simultaneous adenine, cytosine and guanine editing

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5SSGp0RkdhTWRDTGJKMHNScUNXUlJPOXd5V2hLVURQSVFBREtLT3ltZHhzSGhiOW41eGkxTHlkQkZ1elQwdDRpT21TOVhxWHIybVRKM2hBY0lHclJNVWxr?oc=5" target="_blank">High-diversity base mutagenesis via simultaneous adenine, cytosine and guanine editing</a>  <font color="#6f6f6f">Nature</font>

SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping
Naturegeneral

SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8zanJDdDAzNW9JcFZpdURRc0dpSFpZX0hLaDhfeER6NmdzMEFoc1A1TXl3VVY1YnNqV1BhVUhIc093T1pGendER1VfcmZuaGxpX0hLdXUyMDJSNVo1QmJV?oc=5" target="_blank">SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping</a>  <font color="#6f6f6f">Nature</font>

"Base editing enables off-" — Live Google News Trends & Headlines