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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "A second DNA binding site" (30 stories)

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A second DNA binding site in human BRCA2 promotes homologous recombination
Lead StoryNaturegeneral
Sep 15, 2016

A second DNA binding site in human BRCA2 promotes homologous recombination

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE93T0s0TTY0X1N3ZkRkX1R0NWJ1Q0VzMV9mUFR6S0YtdTdWTVpOTFFWcTNXWUNzUzRxWEtTLXZ6QzgtaUJvUGcxM05TUUNPb3pTT1ZVRllR?oc=5" target="_blank">A second DNA binding site in human BRCA2 promotes homologous recombination</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "A second DNA binding site"

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29 stories displayed
A novel DNA-binding motif in MarA: The first structure for an AraC family transcriptional activator
PNASgeneral

A novel DNA-binding motif in MarA: The first structure for an AraC family transcriptional activator

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE1LOXRXNERuTndaeGhDbjNmYmZmelM2YkFUanFCS2tkaHJmOG9ESTlNMWpEQV95b3FLQ1A2NDIzTHpqZV9ucUxFUktXdmh2QnBsY2ttSHNINEdTTnpwcnc?oc=5" target="_blank">A novel DNA-binding motif in MarA: The first structure for an AraC family transcriptional activator</a>  <font color="#6f6f6f">PNAS</font>

cAMP-independent DNA binding of the CRP family protein DdrI from Deinococcus radiodurans
ASM Journalsgeneral

cAMP-independent DNA binding of the CRP family protein DdrI from Deinococcus radiodurans

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBHN3lQWGl0YTllUWd5M215OGJwNnRsbllLenR1aFpDWEpVOGZvUi1teENXODlfZnhxLVNCV3A5R1NqcXRwdHN2VkJqT0g5VktxUVNQcU0tNnl4WkpJTFNN?oc=5" target="_blank">cAMP-independent DNA binding of the CRP family protein DdrI from Deinococcus radiodurans</a>  <font color="#6f6f6f">ASM Journals</font>

Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51
Naturegeneral

Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBtbW1KVDNPc1JxZEJHejZ5RDVwaTN0Wkhmdmd3NWxyYmF5US0weFpQTlk5M19DTXhxWjJ1bk9weUljbkhJanduVFh3dk1TeE9Nd3ZzRjZqWDJSZlU1OGhz?oc=5" target="_blank">Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51</a>  <font color="#6f6f6f">Nature</font>

Identification of the binding sites of regulatory proteins in bacterial genomes
PNASgeneral

Identification of the binding sites of regulatory proteins in bacterial genomes

<a href="https://news.google.com/rss/articles/CBMiW0FVX3lxTE1DZWxYMFNuTDRxLWpONzY4ajdEMmdKdFR1MTdOM0V4Q2tqM0VkRlJGMGhXWmFtV0tfdDBRa1h5S2ZReG5KWDZsOVpFeE5ONlhjeFdwSFZURHFNQ0k?oc=5" target="_blank">Identification of the binding sites of regulatory proteins in bacterial genomes</a>  <font color="#6f6f6f">PNAS</font>

Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription
Naturetech

Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE8xOVdaZThWTlNRYkI4TllSMHQzLVNrOXdtZ0FSRnlrMmczX0U5cnFpNEVTUGxNNEYyVkxJOWRxak9UczdJMk5URlQ2MVdzQzdrU19PVTFmZW1TODR2TERB?oc=5" target="_blank">Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription</a>  <font color="#6f6f6f">Nature</font>

A second calcineurin binding site on the NFAT regulatory domain
PNAStech

A second calcineurin binding site on the NFAT regulatory domain

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE5qTXNvVGxabHM3MVpIdXdhLU5qVks4ckdDeVRPMlJiZ2xUb3NIN2h4VXZDOVlSMGtzaU1pdVYxZ0V1MUdtUzdDT3pvaXp1bzBRV05CV2kxZ1N4SmU1?oc=5" target="_blank">A second calcineurin binding site on the NFAT regulatory domain</a>  <font color="#6f6f6f">PNAS</font>

Cooperative nucleic acid binding by Poly ADP-ribose polymerase 1
Naturegeneral

Cooperative nucleic acid binding by Poly ADP-ribose polymerase 1

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5RTnZfX3p3dlUtQUlxaDc3dUtfN3V3WG53WE1peGVyazZoTWxWMjJGYl9QejZCS2N2aHJ2NTl5UDJOdmpzUExRQWFvMEh0dFNnRHB1MXlJenc4RW9kSFlB?oc=5" target="_blank">Cooperative nucleic acid binding by Poly ADP-ribose polymerase 1</a>  <font color="#6f6f6f">Nature</font>

Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding
Natureworld

Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9ubEYwS0VLMXl0MndpYlVmWmlMaDRzX1dsTDhOcGFtenVhTFY3cWl6aEptbThyb0QxTmp0Ymc2eEtjVlFpSVU3dDMwc2V0MTN2a1EyUmlnU2pkdVhGZndj?oc=5" target="_blank">Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding</a>  <font color="#6f6f6f">Nature</font>

TransBind allows precise detection of DNA-binding proteins and residues using language models and deep learning
Naturegeneral

TransBind allows precise detection of DNA-binding proteins and residues using language models and deep learning

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBUOTBzdDhxeGpQNWpGUTgxUGNRLVFzVjdCTkJmVDdDNk12WVRfN0JJdzJQNUItWEVDcFdxb0RVeFhzNUNmaWFPMURvVWNJMWpBV2dmRG90ZDlYeUhRNFF3?oc=5" target="_blank">TransBind allows precise detection of DNA-binding proteins and residues using language models and deep learning</a>  <font color="#6f6f6f">Nature</font>

Computational design of sequence-specific DNA-binding proteins
Naturegeneral

Computational design of sequence-specific DNA-binding proteins

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5iekY1VmxQYnQ3V1c2bVhwUC1JSTJ4WnkzbFV3bGVDMG9YejJNS2FhWHVnU0d4TWl5V1pVVzZUNkRRQVRteUVJNDhfS2E2Z2JlTE10VmZGcVJKSHZPYXhZ?oc=5" target="_blank">Computational design of sequence-specific DNA-binding proteins</a>  <font color="#6f6f6f">Nature</font>

PDNAsite: Identification of DNA-binding Site from Protein Sequence by Incorporating Spatial and Sequence Context
Naturegeneral

PDNAsite: Identification of DNA-binding Site from Protein Sequence by Incorporating Spatial and Sequence Context

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE9hRUszb2VvMzVoMjc4N2Qyb1NQZlRDdUEzbmNmV3R6Z2l5M0NYY2QzNVN6Rml2NWZCeWRqZUF2SThKZ096TUo4RVJQM1pfcno3U3NB?oc=5" target="_blank">PDNAsite: Identification of DNA-binding Site from Protein Sequence by Incorporating Spatial and Sequence Context</a>  <font color="#6f6f6f">Nature</font>

Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs
Naturegeneral

Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA3V1dSWVZjNXJNRlhuUU12bDJIRzBHemg1RVFTUTZhdDd6RVRIZkkxb2xKUmxhWW8wVm1Pd0VWZm9ZZzdURUJwWm9Hb3lmd3puVDdFWmQwMHpNZ2ZlaVdF?oc=5" target="_blank">Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs</a>  <font color="#6f6f6f">Nature</font>

Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase
Naturegeneral

Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE02NzJnNjZCbUVRa3k5akhJNVg3MmUwYWpCVnNmdWY5a0VhRmZZMFJvaGExSTZIX1owQ2VocEFWN2NKb1RIY1RjaVc2c25ySmJkb2M0dGVfUWlYeDFTYUpB?oc=5" target="_blank">Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase</a>  <font color="#6f6f6f">Nature</font>

Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator
Naturetech

Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBGLWYwMDJwSGE3MFV4YlMtRkEwRnFIRkI0TXljQmhjV0hGSk5HMUVfcDluNkw0WXJYR1hvemJuTW0xcl93Rm1rZU9nTjlPLVJMc3N6ZGQxSGJuLUc3QTBV?oc=5" target="_blank">Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator</a>  <font color="#6f6f6f">Nature</font>

Hidden modes of DNA binding by human nuclear receptors
Naturegeneral

Hidden modes of DNA binding by human nuclear receptors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBTOVY1dmpvaDRoNF9tdXYwWkZkeUQ1RTU4TUNsTkdCdDZvWVJYZ3dqazZVTExGbzRtRlFnMi01SnpTRmd6alVRb0lPdERaNTctS1ItRTZWczFQWENQR0h3?oc=5" target="_blank">Hidden modes of DNA binding by human nuclear receptors</a>  <font color="#6f6f6f">Nature</font>

A compendium of DNA-binding specificities of transcription factors in Pseudomonas syringae
Naturegeneral

A compendium of DNA-binding specificities of transcription factors in Pseudomonas syringae

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA4VDViQUtyRTJvVzg4Wlhsa2s1M092Um16Q2Nuam1yeEZoMkdJYmxkanVxMFQwaUxjQlFoTGNjVW1SVEhYSmdHSGpjU3o2ODIwR09MZlNxbGVWcWlIVThB?oc=5" target="_blank">A compendium of DNA-binding specificities of transcription factors in Pseudomonas syringae</a>  <font color="#6f6f6f">Nature</font>

The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors
Naturetech

The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5VTXhlOHQ0VVlIYXo0V211cmxBMk94SjAzeThBMTAxR09YRm5ia1lodTl6Sy1QTkRtUWdUcnFTbHFhckxHVGNtT2dHVTJmVU9PVmZSOWJXZTM3SUJfamcw?oc=5" target="_blank">The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors</a>  <font color="#6f6f6f">Nature</font>

Substitution of tryptophan 89 with tyrosine switches the DNA binding mode of PC4
Naturegeneral

Substitution of tryptophan 89 with tyrosine switches the DNA binding mode of PC4

<a href="https://news.google.com/rss/articles/CBMiU0FVX3lxTE1HN3JBMEVEOU11NGVsamszOU1udGpRcTFwcnlxX1RTQXlzTWtJSHd5UWRWMDlLQVl6RFEzSFZDR2xMZXdwdmxqQmhyeFFacXcyYU9j?oc=5" target="_blank">Substitution of tryptophan 89 with tyrosine switches the DNA binding mode of PC4</a>  <font color="#6f6f6f">Nature</font>

Structural basis of Nuclear Factor 1-X DNA recognition provides prototypic insight into the NFI family
Naturegeneral

Structural basis of Nuclear Factor 1-X DNA recognition provides prototypic insight into the NFI family

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE01NFZva0ZrcEJnMGNVTkZWYktYLTVISkhkaDk0alF0UVBTUTFVenAtYkpBRUp5akJxcGk5TDVsUEFUSkZwRzJOVk5fOGF1ZWZDekZuTm1PLUtzVkJSUUZZ?oc=5" target="_blank">Structural basis of Nuclear Factor 1-X DNA recognition provides prototypic insight into the NFI family</a>  <font color="#6f6f6f">Nature</font>

De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
Natureworld

De-novo protein function prediction using DNA binding and RNA binding proteins as a test case

<a href="https://news.google.com/rss/articles/CBMiVkFVX3lxTE9WX0t0WTYyRDJVcTE5SDFTTHpDSU8wcFgybTg5NWNTUk92X2tKaU54UWFyV3hIWGpYdEtnQS1YbV9wODZRVFJ4V2oxLUNISnhlVHlVdkJn?oc=5" target="_blank">De-novo protein function prediction using DNA binding and RNA binding proteins as a test case</a>  <font color="#6f6f6f">Nature</font>

Binding of the HSF-1 DNA-binding domain to multimeric C. elegans consensus HSEs is guided by cooperative interactions
Naturetech

Binding of the HSF-1 DNA-binding domain to multimeric C. elegans consensus HSEs is guided by cooperative interactions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9JUE5XVzRRdXBTeXA5c1NXMVktaHhFODhDOHlYMkRpN3R2RDFVSmNkWXE0eHlkbVVaSU9ycG1ZbWJWbXc4TG5lcW1ianhrS0EyNzl1RnJiQ05pWXV0ekNj?oc=5" target="_blank">Binding of the HSF-1 DNA-binding domain to multimeric C. elegans consensus HSEs is guided by cooperative interactions</a>  <font color="#6f6f6f">Nature</font>

Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy
PNAStech

Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1NZHlpLTRjaFRFa1E3YmlqWWs4ckZKb2w2THZnSGZmLXVWcjRHT29rNFJiRk4xbFZOb2dMRGpJMlVpRk9ZUE9sZlFldEtqeHJ6Zkdkc0Y2TkpMbVJl?oc=5" target="_blank">Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy</a>  <font color="#6f6f6f">PNAS</font>

Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance
Natureworld

Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1XS0tBUko4VHUwcVp6dWJUUDZfdkFfcUhrV0ZRMElTT1laTGtFN3A5bkVaNlA3ZlQ1OGlQS19DbFRtZnF1NEtyX0R3aEFyTUpYMGV1ckVvbVZZRTdSem5N?oc=5" target="_blank">Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance</a>  <font color="#6f6f6f">Nature</font>

Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition
PNAStech

Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition

<a href="https://news.google.com/rss/articles/CBMiXkFVX3lxTE00OVYwSTF0cW1jZHl3bEx2RDFFdmhrQWV4Rk5YdDVVeXUtSEc5M21LdE04WEdoUzQ5Ukg0cEd0TTBhdmtmX3FhWmtfQlJoSzY1amxKVll6Q2lYX1cyS0E?oc=5" target="_blank">Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition</a>  <font color="#6f6f6f">PNAS</font>

True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy
Naturegeneral

True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1DMVFiRUJ2WTFmOTVxeWNRN3lwSUx2UmlWcGJCQXRkRHNPZHBhcVk0NmpsdG9tLU56YzlOMEdjS2owaDRiX2hFWnYzNFNxQ1J2aW9yLTF3eVZIWDVBVE9n?oc=5" target="_blank">True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy</a>  <font color="#6f6f6f">Nature</font>

Dividing a supercoiled DNA molecule into two independent topological domains
PNAStech

Dividing a supercoiled DNA molecule into two independent topological domains

<a href="https://news.google.com/rss/articles/CBMiXEFVX3lxTE1aZDJzUW5nd1d1Z2pQSHFCSGpueVI3UTFxYmZBeS15Z2JCdG0tREdheHV0eDJwNDlTT3pDRHI5Mk1EWE40UGVKR1ZNV2hTU2lmUnJfRGV0am1uV2lJ?oc=5" target="_blank">Dividing a supercoiled DNA molecule into two independent topological domains</a>  <font color="#6f6f6f">PNAS</font>

Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites
Naturetech

Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1kZXcyR1RUVU02LVdmTWZBUllPcHVkTjJPSkxsREVjNHJ4WnJPUUVpQzRSeVdoU1l0a2dEUmV5Wk1FWHZlWElpX2h1NGI2TXFHRTFjalczbW9Cbmc5MUlN?oc=5" target="_blank">Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites</a>  <font color="#6f6f6f">Nature</font>

Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes
Naturegeneral

Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBZZjZHTzExSGd4REt2VTdUMVFVWkVDaWZKV09XRW9WSkVhelBnWC1pMU00ZUdObWNuTjdEZzVBTnZ0NEFvRTUyUWRvbmh4VGdQSEkwYlkzV2NuR3FWaEcw?oc=5" target="_blank">Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes</a>  <font color="#6f6f6f">Nature</font>

Replication gap suppression depends on the double-strand DNA binding activity of BRCA2
Naturegeneral

Replication gap suppression depends on the double-strand DNA binding activity of BRCA2

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB0bU9DczhBRUJkaFNnMVNVcmoxbWRfbWtOVHcwdEdfZTBELTBhN3I2WWdWNHAzTEprZ1RkYnZDTkdtQlZVTXR1dG5NNXpIV3ViNW1qWTZ6QUlBeXlwN1FV?oc=5" target="_blank">Replication gap suppression depends on the double-strand DNA binding activity of BRCA2</a>  <font color="#6f6f6f">Nature</font>

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