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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "A Mechanistic, Multiscale" (30 stories)

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Mechanistic multiscale modeling identifies putative natural tri-target candidates of MAO-B, LRRK2 and A₂A for Parkinson’s disease
Lead StoryNaturegeneral
May 5

Mechanistic multiscale modeling identifies putative natural tri-target candidates of MAO-B, LRRK2 and A₂A for Parkinson’s disease

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE42bmlycnYtMmktVkhid3AtU1pXV2pZekpjcWpLNnVXdE5ya3ZpYzlNRGNWVlRkRU05YVRaV2ZTZEcwWWRGS3BkRUdiTGJzMmZVNmlPakpYUzF1R2oxQU9B?oc=5" target="_blank">Mechanistic multiscale modeling identifies putative natural tri-target candidates of MAO-B, LRRK2 and A₂A for Parkinson’s disease</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "A Mechanistic, Multiscale"

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29 stories displayed
AIRE transcriptional condensates in central tolerance: a multiscale mechanistic perspective
Frontierstech

AIRE transcriptional condensates in central tolerance: a multiscale mechanistic perspective

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxNSl9rUmktWDBHQnhVYXAtVi1sTXdnTGhIMWVVVF9JbDFwdm5mNms1NFJuQjRjbjg0V0sxd0pvNVZibFZJSlA4Uy1Ra2J2QkZzZWJaVW9zb0VnS2VsQTJKVkZwZjYxbXY4UXlZdXRzR3NoTl9FT1dTYlpramQ5NVQ2bS1KaFN3TnQyVklBcmZYb25uZw?oc=5" target="_blank">AIRE transcriptional condensates in central tolerance: a multiscale mechanistic perspective</a>  <font color="#6f6f6f">Frontiers</font>

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A hybrid multiscale model for predicting CAR-T therapy outcomes in solid tumors
Naturegeneral

A hybrid multiscale model for predicting CAR-T therapy outcomes in solid tumors

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE4wMXVwVmxIRnNNRDJzUnpBRU5xYURHQXRXcm5zM1RyMGp0VERpSVJHckl5MTFXWXg4WS1wUGV6UVBFZDdtUUg3bkRscm10aGFMN1Bid3k2bDlNSHFCb1BB?oc=5" target="_blank">A hybrid multiscale model for predicting CAR-T therapy outcomes in solid tumors</a>  <font color="#6f6f6f">Nature</font>

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A Mechanistic, Multiscale Mathematical Model of Immunogenicity for Therapeutic Proteins: Part 2—Model Applications
Wiley & Sonsworld

A Mechanistic, Multiscale Mathematical Model of Immunogenicity for Therapeutic Proteins: Part 2—Model Applications

<a href="https://news.google.com/rss/articles/CBMibkFVX3lxTE5jVjhlMlJlZElCZ2NvSWx6UmNBNkRkSjY1RUZKdHp4UjRWNGwxQmNiWHRxeEE1S2lzeWVVMFhza2IzMm5GVkZacXZweXllRFFhWV9IVUZ0amNnYW14OWlzTDRRSU5zYmdxMFNYdURR?oc=5" target="_blank">A Mechanistic, Multiscale Mathematical Model of Immunogenicity for Therapeutic Proteins: Part 2—Model Applications</a>  <font color="#6f6f6f">Wiley & Sons</font>

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Multi-scale digital twins for personalized medicine
Frontiersgeneral

Multi-scale digital twins for personalized medicine

<a href="https://news.google.com/rss/articles/CBMilwFBVV95cUxNNkNKNUNPZ0pDbzh5TVp1Yms4TGZwdndfMHpvWW1MUnBaMGZva1M3aTN3YnMyc0x6U0M3SEYtZkI1THg1N1lCTElHSldUbnQxcFJFTUcwaGNPeGwxMW0xWHRRLXA2ckc0bFRXZzRVTG5rZEstTHNZMTA3UlB6b0w1cFNmQnpjNkQzSlJuOU5TeUV6QnRsLW1j?oc=5" target="_blank">Multi-scale digital twins for personalized medicine</a>  <font color="#6f6f6f">Frontiers</font>

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Multi-scale mechanistic evaluation of reactivity balance in metakaolin-nano-CaCO
Naturegeneral

Multi-scale mechanistic evaluation of reactivity balance in metakaolin-nano-CaCO

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5ucHAwSTZIN0wyWHRoVEpraW55bERkSUdBQ0ctSHRJZHlEOXRWbndyeW1fTkhqb2ZlcFJlbkY3WEtvRjc1Zm4yZHRXbDNOSDhPdEMwYTFBa2dCSnJjcng0?oc=5" target="_blank">Multi-scale mechanistic evaluation of reactivity balance in metakaolin-nano-CaCO</a>  <font color="#6f6f6f">Nature</font>

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Experimentally calibrated multiscale model predicts schedule dependent drug combination effects
Naturegeneral

Experimentally calibrated multiscale model predicts schedule dependent drug combination effects

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5icktuaDhwOFpQTjJsS0JHMXMzajkwSjVVNGNkeGlOVklPVEFvRnFveHhmaXU4RnJyN3FRdUstZ1dsSjRNRk8wdnJwNHQyVllDOE1pdmhvWGZJYzNnT3Ew?oc=5" target="_blank">Experimentally calibrated multiscale model predicts schedule dependent drug combination effects</a>  <font color="#6f6f6f">Nature</font>

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A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery
Frontiersworld

A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxPMURFUWxpVWUtMlF1MG1OS1plTDFuM29yZGRldDg1ZnpzT0w2YnQ1SGtXWUdSRWxiYkNGZUg2bWUxMmpzM3ZvaDd5dzZodnRpdXM4T21Cc3BmaFpRV0ZHTW9uV1o1eHJXMjlNTmh0ZlBoc19mcmN5anRheTNGaEhXZHkybkhCTUlvMmVFaWZkT2syZw?oc=5" target="_blank">A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery</a>  <font color="#6f6f6f">Frontiers</font>

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A Multi‐Scale Mechanistic Model of Ulcerative Colitis to Investigate the Effects of Selective Suppression of IL‐6 Trans‐Signaling
Wiley & Sonsgeneral

A Multi‐Scale Mechanistic Model of Ulcerative Colitis to Investigate the Effects of Selective Suppression of IL‐6 Trans‐Signaling

<a href="https://news.google.com/rss/articles/CBMickFVX3lxTE1YcW1UZFBPUTRDa2p0dU5lSEp0THItcTRiN3hiVDBYNDh1eWJtT0ZzV0lTeUowMm5vSnVKSVI5c0pINHBFdHF3ZkE5WlNmMnVCeW83ZEJYMjY2enI4QXhBVXFuVU1WaUxmeHZuUnhSd2pYZw?oc=5" target="_blank">A Multi‐Scale Mechanistic Model of Ulcerative Colitis to Investigate the Effects of Selective Suppression of IL‐6 Trans‐Signaling</a>  <font color="#6f6f6f">Wiley & Sons</font>

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Martial arts induce quasicritical brain states: a unified, multiscale, and mechanistic theory of brain health optimization
Frontierstech

Martial arts induce quasicritical brain states: a unified, multiscale, and mechanistic theory of brain health optimization

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxNVlhZUG1aYkVrNEx6dXZVOFZvanpZSmt0VU1jc2ZqQm1yYWUtMXl0UTh1WVRRd202UHhYUW9GUnN4X3VyS1B6M1h1SlR6Qlg0MVNIakVETjNVeUg1WHZMUW9iRmlGNEZ1QS10dFJRenZ5NkNlWkVaaXNPNFlqZmNrclUtQkZKRzkweU13SXFqS1BXZw?oc=5" target="_blank">Martial arts induce quasicritical brain states: a unified, multiscale, and mechanistic theory of brain health optimization</a>  <font color="#6f6f6f">Frontiers</font>

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Multiscale systems modelling of communication networks in brain metastasis
Naturetech

Multiscale systems modelling of communication networks in brain metastasis

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9vbzRKMTRRZWlLemxuVEJic2gwU0x6MVlRcDZDclc2ZjFxOE1KWTlNNXVGc2t6VFpzYThSUWZrazlGczEzX29naFZKeWwxNUF3OHkzMmtlNzFqaUhWbDBj?oc=5" target="_blank">Multiscale systems modelling of communication networks in brain metastasis</a>  <font color="#6f6f6f">Nature</font>

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Biofabrication for spatial control of multiscale biological crosstalk in tissue models
Naturegeneral

Biofabrication for spatial control of multiscale biological crosstalk in tissue models

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE96ci1oVGhSbzgwcHc2TkpmSjBBeDZXN3JLMTVnRHhjR294ZXk2cm5nOG5La3QwNVVjRkFhYjJrc0dJZ21tai1CeWY1VDBhY2pfTnBIVXl2Y0NmQXJkZE1B?oc=5" target="_blank">Biofabrication for spatial control of multiscale biological crosstalk in tissue models</a>  <font color="#6f6f6f">Nature</font>

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Illuminating HBV with multi-scale modeling
Frontiersgeneral

Illuminating HBV with multi-scale modeling

<a href="https://news.google.com/rss/articles/CBMimAFBVV95cUxPVlhyelkwYXUzZmRlQWZTdGVrUU11QVlmUUEyZTJhWU5HaHFfc2xxVXY0MDdCYzhva0ozTGdXOUlTMGM3OWRMTUtqczUtUnRpQmIwX00wcWlaTno0YjlaaHBZTEVmbzROY3NBOWZkY2h5eUNPNnR6THdOWTAyTF9COWlhS1dhaWJlZ1R4d0t5czBYTzJzRUd6eg?oc=5" target="_blank">Illuminating HBV with multi-scale modeling</a>  <font color="#6f6f6f">Frontiers</font>

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A multiscale analysis of compressive stress-enhanced carbide precipitation in deep cryogenic treated martensitic steel for shovel teeth
Naturegeneral

A multiscale analysis of compressive stress-enhanced carbide precipitation in deep cryogenic treated martensitic steel for shovel teeth

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE12YWN0VzBrZmxKanVZTnhZaldoSDZheUlpUUJocWRNZ0hKQ25UVENUdWphUWtRa3dIdWJsaU9pZTJadXdjdU51REZGRzV4T29MTmV3WDN3Q0lWelcyLWxJ?oc=5" target="_blank">A multiscale analysis of compressive stress-enhanced carbide precipitation in deep cryogenic treated martensitic steel for shovel teeth</a>  <font color="#6f6f6f">Nature</font>

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Multi-physiology modeling of the immune system in the era of precision immunotherapy
Frontiersworld

Multi-physiology modeling of the immune system in the era of precision immunotherapy

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxOZ0gyZFlKdFotQ0IwME5JbW9TUFlTLXFoUjJkRjBQZ19hSUlkajQyVzcxV0prSGJuaDdVUXQtb0dkVEFKdHlBZWw5LWQwZGpjUkhITlI5YlFYSndnYkc1em1BZlFMczFqMnVuY2VRbmdiQnE3OU9NMEVHMFhDTjhMMXdvaWVqemJzVl9ydXBXdnd2UQ?oc=5" target="_blank">Multi-physiology modeling of the immune system in the era of precision immunotherapy</a>  <font color="#6f6f6f">Frontiers</font>

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Vascular dementia: novel insights through multiscale mechanistic modeling | Signal Transduction and Targeted Therapy
Naturegeneral

Vascular dementia: novel insights through multiscale mechanistic modeling | Signal Transduction and Targeted Therapy

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9oU0JnV2QzVE1xUFE5SzA3Y1R0Z0NhVTFoOFBWcVNzU1pXU2phd01kRGxkYkxHMlB2a3E5clhObXotWFZxcFd6c3VIVkZ2M3ZUemttVWRycldybjlrQ3A4?oc=5" target="_blank">Vascular dementia: novel insights through multiscale mechanistic modeling | Signal Transduction and Targeted Therapy</a>  <font color="#6f6f6f">Nature</font>

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Exercise as a multiscale recalibration of stress-related homeostatic balance
Frontiersgeneral

Exercise as a multiscale recalibration of stress-related homeostatic balance

<a href="https://news.google.com/rss/articles/CBMilAFBVV95cUxQbnJYSEtlSkNDdGVSNkZmZGMtYzUwVzA5eE1IWkpPcVhBeXlRUEozRmNHYWdJcnZGaWlfUktUMHoxcUMxeUxKLTVhNGxmWnZGNmpNWHB5aWhTVEZVLWdfUURnN19xQXYzVk14RDlkSVNlc25VT2Q1YmhQdVVfWHlqeEN1YndkYjdNV2lhZV9fMFF2SW1X?oc=5" target="_blank">Exercise as a multiscale recalibration of stress-related homeostatic balance</a>  <font color="#6f6f6f">Frontiers</font>

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Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development
Naturegeneral

Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBncmwtNUhRN2g5TTVLSXdUd1ZwMTZDLW1wWU5NQlRGZEhqUDd1a203dGwzSnRBbVdsM3FWbFdpV2RpMjM1NXlZcUY4WG8yTzVnY1VKaHhocTlXX0pfSldZ?oc=5" target="_blank">Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development</a>  <font color="#6f6f6f">Nature</font>

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Mechanistic exploration of polytetrafluoroethylene thermal plasma gasification through multiscale simulation coupled with experimental validation
Naturegeneral

Mechanistic exploration of polytetrafluoroethylene thermal plasma gasification through multiscale simulation coupled with experimental validation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFA0X2pkUjBrS1ctbTlYa1RleG5OSTM5OS1nQThjV05CYkJYR3U4NGFOTS15WDdHYVI0Q3JHQk04dEd4NktveWlhc2l0THpGT0d1WkNLM2VxbldOSE5NN0pF?oc=5" target="_blank">Mechanistic exploration of polytetrafluoroethylene thermal plasma gasification through multiscale simulation coupled with experimental validation</a>  <font color="#6f6f6f">Nature</font>

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Evaluating neoantigen-vaccine responses through mechanistic and model-based frameworks
Naturegeneral

Evaluating neoantigen-vaccine responses through mechanistic and model-based frameworks

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1yUEtvSVd6dVBOd1ZYWk5kUFRaMW0xTDJEbUlNWlJHYmN2VWtnVE5oM1NuVDhORi1QaVVuakI4bElnd0ItTE9yOHZOcHhBSU51Y2p1Q25GMHJkV2Y4Yndj?oc=5" target="_blank">Evaluating neoantigen-vaccine responses through mechanistic and model-based frameworks</a>  <font color="#6f6f6f">Nature</font>

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Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons
Journal of Neurosciencetech

Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons

<a href="https://news.google.com/rss/articles/CBMiYEFVX3lxTE5PbVA5Ym1zT2thYW0xZjFpV3VmQWl6eV9JWl9uS1JHVGJpUXNPSDB1Q2FvTFVJMkgwVHhaTmNsOEIzODQ3RnhpaDRtemFvN3JNTzFhQzJsUHAxbWRuRU9HZQ?oc=5" target="_blank">Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons</a>  <font color="#6f6f6f">Journal of Neuroscience</font>

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Editorial: Multiscale cancer modeling, in silico oncology and digital (virtual) twins in the cancer domain
Frontierstech

Editorial: Multiscale cancer modeling, in silico oncology and digital (virtual) twins in the cancer domain

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxQSFlHdjE5ZVQtUUxpb3VkaUNkNGtybFpYX2RRSmw5ZG1xYkx5VmZoLXg2U0RCcjVMVXdOYUhSdFJHaEZHY1FOTnlWbVNGUy00Nkh4LVIxX2pYYzJhVHVKd2xfRWhrQ240d1lzVE9vcGp0RWZwaHJSR0hsVEdKQ2lkWm9sTGx5T01WV2UzWkRWVjY1QQ?oc=5" target="_blank">Editorial: Multiscale cancer modeling, in silico oncology and digital (virtual) twins in the cancer domain</a>  <font color="#6f6f6f">Frontiers</font>

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Multiscale modeling of drug-induced liver injury from organ to lobule
Naturegeneral

Multiscale modeling of drug-induced liver injury from organ to lobule

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9UelladFBDSGNjN3NoRzlwT3dvS2QzRmhrd3dCWlpvOEZQemwzMlJkdjAybXRkM2xHV1d5VzNMT19mbmhuSXFOZVdjRzlReGY3X1JpRXZSM0g3NXRwclNZ?oc=5" target="_blank">Multiscale modeling of drug-induced liver injury from organ to lobule</a>  <font color="#6f6f6f">Nature</font>

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Revealing multiscale competing processes in the solid-state synthesis of single-crystalline layered oxide positive electrodes
Naturegeneral

Revealing multiscale competing processes in the solid-state synthesis of single-crystalline layered oxide positive electrodes

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1fQ3BVaElBTk5XNjYwTzNpcHZlcXdWYUp1bGxaeXhtMnQ3YUk2T0kyZ1FYOWZlaEppQmpRMEpJa0dKblM5SVBvdEFuS3BVeWpWTjBPOTFiMXlYQlRoOXE4?oc=5" target="_blank">Revealing multiscale competing processes in the solid-state synthesis of single-crystalline layered oxide positive electrodes</a>  <font color="#6f6f6f">Nature</font>

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Commentary: GETgene-AI: a framework for prioritizing actionable cancer drug targets
Frontierstech

Commentary: GETgene-AI: a framework for prioritizing actionable cancer drug targets

<a href="https://news.google.com/rss/articles/CBMimAFBVV95cUxOMzZ4NVBsYWhHc3QtSS0xTEl4TVA1WGMwaTR3QVFZMW9fMHZJU1VjNnpYaVg2Q2xKN0xxT1Y3N3YtaFN1eGlvLXZ0dFNPclJpb21lRGNJU3kxRXF2Q2JLNW5VeFlwREdxVmp2Z0R4NjA3Z05PaTA5VTlmUGhWeUhxa19JOW9oQ2xCcDFyODVrNC1LNHA3ekVLTQ?oc=5" target="_blank">Commentary: GETgene-AI: a framework for prioritizing actionable cancer drug targets</a>  <font color="#6f6f6f">Frontiers</font>

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Editorial: Virtual patients and digital twins in the systems analysis of drug discovery and development
Frontiersgeneral

Editorial: Virtual patients and digital twins in the systems analysis of drug discovery and development

<a href="https://news.google.com/rss/articles/CBMimAFBVV95cUxONUR6dl9UMHppeE5JdEJJZVlUUTNNaXpxMGlQZFNncWNQMERDX1FTVlprWF9QWEdxSDFVb1NfMzBKc29SMG1yQmpYc1djZGpGTmt0ZDF1VU1uTGg5bVZ6RzgtbmNSVmZoMThCRkZlV0tJME5lejBoRHFZdkRjV1pHVkV6R1UycVYwLXFBUk5YbFY2dUExX2RxTA?oc=5" target="_blank">Editorial: Virtual patients and digital twins in the systems analysis of drug discovery and development</a>  <font color="#6f6f6f">Frontiers</font>

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Multiscale time-domain NMR for structural, water, and texture characterization of meat and plant-based food matrices: a mini review
Frontierstech

Multiscale time-domain NMR for structural, water, and texture characterization of meat and plant-based food matrices: a mini review

<a href="https://news.google.com/rss/articles/CBMijwFBVV95cUxNNnhHR2lRVFVQT2hLZDJJTE9rZFIyQzRlQTlKc05keWNjWkVMUVZjY0lMTDNsajdwRVZxeFZkc2ZUaC1PbnVrYTRqdWFsZ29VY3pETFlBWEZwVUJZM2NmUVFfUEZMZ0NLUE5WQlI5cU1aR0lxd1Y4aTVZSkZDSE9YNGxTRHFIMHZVR05SVE1WWQ?oc=5" target="_blank">Multiscale time-domain NMR for structural, water, and texture characterization of meat and plant-based food matrices: a mini review</a>  <font color="#6f6f6f">Frontiers</font>

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Immune digital twins for complex human pathologies: applications, limitations, and challenges
Natureworld

Immune digital twins for complex human pathologies: applications, limitations, and challenges

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5EZFQ3LUw3WjlMOHJyVF9ZSXNocUo5MXVMX2pTSEs2aHhOWGpCczRjZFMyWGtsalNkaVBJbzl2YnVlWG52aGpmMTFOTXlMR2V5R2pJMUptZTNTUGxENl9j?oc=5" target="_blank">Immune digital twins for complex human pathologies: applications, limitations, and challenges</a>  <font color="#6f6f6f">Nature</font>

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Excitation–inhibition homeostasis in Alzheimer’s disease: a selective multiscale review of mechanisms, sex differences, and therapeutic opportunities | Neuropsychopharmacology
Natureworld

Excitation–inhibition homeostasis in Alzheimer’s disease: a selective multiscale review of mechanisms, sex differences, and therapeutic opportunities | Neuropsychopharmacology

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFBIQjJmeGhjU051MzVjdkdXUXhLS0x6VzVHU21KbWdEMm5YNXpfbERyd3dxdHAycWVTaWV3VGVEeVRERmV1Yzd3WHJUZWJBNkVBRnNRU0RmaFhmd01oYXhr?oc=5" target="_blank">Excitation–inhibition homeostasis in Alzheimer’s disease: a selective multiscale review of mechanisms, sex differences, and therapeutic opportunities | Neuropsychopharmacology</a>  <font color="#6f6f6f">Nature</font>

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Systems biology during 20 years of PLoS Computational Biology
PLOSgeneral

Systems biology during 20 years of PLoS Computational Biology

<a href="https://news.google.com/rss/articles/CBMihAFBVV95cUxNLTd4cGRoNmh4M2N3U0NnN0UyU2c4cW8zbjJIV09mcW43QXp0VkVWT0xxNVcwckFFUzVfaUltc2dQT3NrQmFNWXM2VkdsRHlfOUwxeEVNTlZtMGdFMXE2QmwxWnk2akVlVkl3blRYRUtITVpYSlBrSlJzUlpzQndNMjBaZEM?oc=5" target="_blank">Systems biology during 20 years of PLoS Computational Biology</a>  <font color="#6f6f6f">PLOS</font>

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"A Mechanistic, Multiscale" — Live Google News Trends & Headlines