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Category:All HeadlinesWorld & GeopoliticsMarkets & EconomyTech & AIPoliticsSearch results for: "Programming inactive RNA-" (24 stories)

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Programming inactive RNA-binding small molecules into bioactive degraders
Lead StoryNaturegeneral
May 24, 2023

Programming inactive RNA-binding small molecules into bioactive degraders

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE9Ja19ENTlPcy1JQ25mVk9raUVrZU1wNVk2emM0WEZzRUF0Zkg5QkRVOGdmZnJEalNtdU50MWJlTVRWc0dVX3lrY0dLVHJEX2R4UTJFRWExcGNGOW1TM1lv?oc=5" target="_blank">Programming inactive RNA-binding small molecules into bioactive degraders</a>  <font color="#6f6f6f">Nature</font>

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Search Results for "Programming inactive RNA-"

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First-in-Class RNA Degrader Targets Historically "Undruggable" MYC in Preclinical Multiple Myeloma Models
Pharmacy Timesworld

First-in-Class RNA Degrader Targets Historically "Undruggable" MYC in Preclinical Multiple Myeloma Models

<a href="https://news.google.com/rss/articles/CBMi1AFBVV95cUxNdURrQ1lJaEdZRzA0U3NJd0NSRDVGTTBjYUtxQmY5NUUteEdCMGtwNG5kRUttRkdvUzdENFVtQ0RLTl9fUTg1aDFPckpSNmpYYkNvdk55WFBROGxTdlRkdGJGeW9nTmZTd1ZybHZGanE4UE1WUkxuQWlqSW9wLURocExibk9hU0dXMWN1SEgtVHdpWkIzYUVTUlNLbU1iRkxWT1hwc01UQU12bWNub3p1SDVXMmluUVZvN2pjSzBRTmV4NVY4bGdXeEhXX2l4MmpFWnVoSQ?oc=5" target="_blank">First-in-Class RNA Degrader Targets Historically "Undruggable" MYC in Preclinical Multiple Myeloma Models</a>  <font color="#6f6f6f">Pharmacy Times</font>

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MYC is no longer untouchable: RNA degradation as a new therapeutic strategy in hematological malignancies
Via Medica Journalsworld

MYC is no longer untouchable: RNA degradation as a new therapeutic strategy in hematological malignancies

<a href="https://news.google.com/rss/articles/CBMigwFBVV95cUxOTkNmS3NyeEZoTjFnUC1HZzBuYXY5SmhfdE5idFlFMzhXb2RHeG9GOFBZMXh5R1FlcjRtVUZtVTU2dE9PTVBmamFHeWliLUpoS21iUDdJTEZuRXFQenA0Z2MzeGNhT2dhNno0YUs2ZmYwb2lKeGdKRnZjOWJWVkplYU94Yw?oc=5" target="_blank">MYC is no longer untouchable: RNA degradation as a new therapeutic strategy in hematological malignancies</a>  <font color="#6f6f6f">Via Medica Journals</font>

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Life with two X chromosomes | Royal Society Videos
Royal Societygeneral

Life with two X chromosomes | Royal Society Videos

<a href="https://news.google.com/rss/articles/CBMiekFVX3lxTFByQ0ZzV2ZSNDVmcmNhemJ2c0dLOTBXNjhVMDB5TmZlUW9kcVhFQkFEU2dJRjJ4V2lWdzZwajZJT2RSaG9OUTBwUG1jMG1pZFpnbVA1Y3hPN1NIcXNZNzRId1lpcWlFMlhkMHJhNmo5a0VzY0ROWmJXOGhR?oc=5" target="_blank">Life with two X chromosomes | Royal Society Videos</a>  <font color="#6f6f6f">Royal Society</font>

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Small Molecule Conjugates Unlock Targeted RNA Degradation
Genetic Engineering and Biotechnology Newsworld

Small Molecule Conjugates Unlock Targeted RNA Degradation

<a href="https://news.google.com/rss/articles/CBMirAFBVV95cUxNenZXZlM3empkMVVZc3Ytc053YnlnRUVZaWE3LWhDd0hSWFJpU0FCT2twbzRxSWs2aGEtYUhtUHUxQm91QW9jOEtackczMEFiN2xKVUVULXBsdnhOdjlHdm0tdmQ0OHlWbHMxRld1cW9MNERFbWdGWk9XNlozYlFYMHRxMkZELVZKemUzTnkyRHNMQ1hGaUtNdUctc0V6V0VxdndZaDBhTHZ4cDhR?oc=5" target="_blank">Small Molecule Conjugates Unlock Targeted RNA Degradation</a>  <font color="#6f6f6f">Genetic Engineering and Biotechnology News</font>

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New gene-editing method could advance regenerative medicine
UIC todaygeneral

New gene-editing method could advance regenerative medicine

<a href="https://news.google.com/rss/articles/CBMikAFBVV95cUxNZTI5SGVzck9udFlpMEQwazdWekRJTUxSUzlGVXo0dGpfb2hQSVY5eElSMlE3ejZZZDJaT0VrSzQtcWRubVBDa0l6Z09QS1dYdGZValNCLVUzZHVnekF5Ym1mQmFpaEotUWRSU2ZDdU5vS1BucFBkWV9QMkdsM01EcDZ1d0JPTEFVUHVZRlI2eUs?oc=5" target="_blank">New gene-editing method could advance regenerative medicine</a>  <font color="#6f6f6f">UIC today</font>

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Small‐molecule drugs as RNA‐targeted degraders - Huang - 2023 - MedComm – Future Medicine
Wiley Online Librarygeneral

Small‐molecule drugs as RNA‐targeted degraders - Huang - 2023 - MedComm – Future Medicine

<a href="https://news.google.com/rss/articles/CBMiZ0FVX3lxTE9fYXlFcm4wTlc1cnhZRkFIQWtGN3hlUEU0WmpYeVV3MW1ES2hhY0VSdTZKVUQxazU0NWNVTW9BNHZmMkVoa2dCQXBnM3dfOEFRNmxZTmlMQlMtN1F3X3Y3bTJ4dTJPRFE?oc=5" target="_blank">Small‐molecule drugs as RNA‐targeted degraders - Huang - 2023 - MedComm – Future Medicine</a>  <font color="#6f6f6f">Wiley Online Library</font>

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C methyltransferase essential for sperm flagellum assembly
Naturegeneral

C methyltransferase essential for sperm flagellum assembly

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5FMTBIcFF3UXNZWUxLTDhjeDdmTklFUlllZzNlX3RXYkcxdWpmTjdSTHRDUkF1dDhNLU9rV3FBTkJYQTYzWG9pSmpyZDJZbGttd3laTlJJNGRDNFd2QzVV?oc=5" target="_blank">C methyltransferase essential for sperm flagellum assembly</a>  <font color="#6f6f6f">Nature</font>

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New RNA Degrader Approach Tackles the “Mount Everest” of Cancer Targets
Technology Networksworld

New RNA Degrader Approach Tackles the “Mount Everest” of Cancer Targets

<a href="https://news.google.com/rss/articles/CBMizAFBVV95cUxONXF6cERBZWtHVkpWMUZkMzNCVzFvMk1iZ05Xa1YwMTZ0RFBEN3NCeWJ6ODhKdS1Lek9rZ2hGb0ZyZ0hoaXk4QzhSQzd4QkZQdWdiM2FfbzdQaDBucXVpdWluUUUtQ1V0M0lPdWpmTDRmZG1UNGt5MHY0VURmRE5XNkhLdVpQX0YtQzV0MmdJOWhLR0dwTjVkXzkzbVZpN3F6Vlc4NnNQckhNV241T2F1TzVBODFSQVlFMEFwYVp0cHB4RWI1dnZNTEJYMFQ?oc=5" target="_blank">New RNA Degrader Approach Tackles the “Mount Everest” of Cancer Targets</a>  <font color="#6f6f6f">Technology Networks</font>

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Function by Structure: Spotlights on Xist Long Non-coding RNA
Frontiersworld

Function by Structure: Spotlights on Xist Long Non-coding RNA

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxPNVpjVlFXNFBRdlNqbHJCVDE5V2xURWdEM1kwdVBpU1FFc2JiQnN1Zmx5ZXl4bVNLeWtvOHRaT0tIdjhnZTFaQWc4bW8wSlE0YjJpcTJhYk02UDJBcW1HaldiOW5nOVp3ZDI5RTdWTmd1NkYwVHlkWUllWWFuZ0VXMVl5Nzh3OG4zNEtLZHN3NHA4QjVsTkFxMDdpb2k3UQ?oc=5" target="_blank">Function by Structure: Spotlights on Xist Long Non-coding RNA</a>  <font color="#6f6f6f">Frontiers</font>

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Switchable CRISPR-Cas9 guide RNAs for sequential gene editing
CRISPR Medicine Newsgeneral

Switchable CRISPR-Cas9 guide RNAs for sequential gene editing

<a href="https://news.google.com/rss/articles/CBMinwFBVV95cUxNSlpoT2x4RFRPWl8yT0N0dzd4Nk5nMEh4YzM5ZUp3V1ByVUpENXJWdTVUQmdZRHc3ZzNIVG5CeGNEMjBjQloyajF6RjNNTDJhMlBBdkhnQTJSblBQTnNHd0daUW92VEt6NjhCdm1JMFowT083ZXJsV1V4d1Z1cTBPa1ljdFdnRjgzYVFPTG1ZNEx0blhWRTBNemwyUnlxd2M?oc=5" target="_blank">Switchable CRISPR-Cas9 guide RNAs for sequential gene editing</a>  <font color="#6f6f6f">CRISPR Medicine News</font>

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Escape from X inactivation is directly modulated by Xist noncoding RNA
Naturegeneral

Escape from X inactivation is directly modulated by Xist noncoding RNA

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE54RVZOemRoMHJ4dDJRWnlQUWttYlNFOUtid01kdVhnZTkxUHEzYVpiVWIwTm9rcWkzZ3FmS0Fiai15cElvbWtGZFFweVcyOW45NHlvQWF2VDdSdHZhbElz?oc=5" target="_blank">Escape from X inactivation is directly modulated by Xist noncoding RNA</a>  <font color="#6f6f6f">Nature</font>

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The role of long non-coding RNAs in genome formatting and expression
Frontiersgeneral

The role of long non-coding RNAs in genome formatting and expression

<a href="https://news.google.com/rss/articles/CBMijAFBVV95cUxQYnhqWHBOemFuYXhvakFYR2UyVHJ3eGQ4dE5kQVRhU20wOVFQSG92UlRGNFZSQ3Jqc3phMDU1QjU1cXBJbXB6ZjVtd1FCZUdtTExOZFhhY3pVS1JBSVp1VlU5TXNjRmJidzNHT3FvSWtrdHNiZG1heG9kMmx6UEszQ0xlekwxR2pGN24zSg?oc=5" target="_blank">The role of long non-coding RNAs in genome formatting and expression</a>  <font color="#6f6f6f">Frontiers</font>

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A strategy for small-molecule RNA degraders
Naturegeneral

A strategy for small-molecule RNA degraders

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE03VXhPWi0tcTcwV0NDRFJTai1xd0tJR2U3cVRScjVEWk9JUFZYLW44cHI4Y1FBS3dHSXU1VGthZEhsZWJVNnNkRE11ODdsSVBXWHZ0ZGdIbTNJVkE2WXA4?oc=5" target="_blank">A strategy for small-molecule RNA degraders</a>  <font color="#6f6f6f">Nature</font>

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Roles for Non-coding RNAs in Spatial Genome Organization
Frontiersgeneral

Roles for Non-coding RNAs in Spatial Genome Organization

<a href="https://news.google.com/rss/articles/CBMiqgFBVV95cUxObGFZdlZ4cXg2dE9UdDJ1V29EVXF2UnhmQTcwcHZIR08tTlJSWWVGMFAzMXRuNFRsTF9ZNEgzNkN4cGZ2bG8zMk1DQW1xaG9IWThPNjNPLTJybmZsWWtodHp3ZGFFbndGaVlic0FhU2k5dmtrVmd2al8zOUVWT0ZqVk5rWDNsa2V1YzVwbGRkcWFMN3N3TFdCM01FS29hMjFzcEdoSUx2Ym4xQQ?oc=5" target="_blank">Roles for Non-coding RNAs in Spatial Genome Organization</a>  <font color="#6f6f6f">Frontiers</font>

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Long non-coding RNAs: Potential therapeutic targets for epilepsy
Frontiersgeneral

Long non-coding RNAs: Potential therapeutic targets for epilepsy

<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxOWGxBX1YxWGJSV0pfR1QtNklCeW1fb1BBd0lkSEVYVjFIMHJGLTJYNmlDUEMxNUViWTZKNm9YNS1OSnh6UFNuMFJkemtmbUI5OUhsT0VmN29JdUtfa1dxamdZcXp0eWJyMzB6TE1TQ2ZOai0zRGJSa2QxUTdYWXdrRFJHNmREbkZFYXhCenJoSU5NaVE?oc=5" target="_blank">Long non-coding RNAs: Potential therapeutic targets for epilepsy</a>  <font color="#6f6f6f">Frontiers</font>

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Decryption of sequence, structure, and functional features of SINE repeat elements in SINEUP non-coding RNA-mediated post-transcriptional gene regulation
Natureworld

Decryption of sequence, structure, and functional features of SINE repeat elements in SINEUP non-coding RNA-mediated post-transcriptional gene regulation

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5FZXkxanVHM0tqalZVcUdnRzBxbTM3QVhQb1cwUjB5Ykg0NFJNcUFWeUNnY3pSU0xIRUlEZ2JwYUc5UlYzZUtiUXo4RDVvNWFnSWxHNHdqRU5sSlM5WjNF?oc=5" target="_blank">Decryption of sequence, structure, and functional features of SINE repeat elements in SINEUP non-coding RNA-mediated post-transcriptional gene regulation</a>  <font color="#6f6f6f">Nature</font>

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Gene regulation by long non-coding RNAs and its biological functions
Natureworld

Gene regulation by long non-coding RNAs and its biological functions

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1iajFaODBBaWJ0Tk16MzJBSzZNT2xYcEJQb0VNazljc25YQUVCNFh5S054MmhTR0czai16Vld4Zm5DeEtkWWJTOXBScTcxRzlUOUdrOE9JWF9FdzctQlRn?oc=5" target="_blank">Gene regulation by long non-coding RNAs and its biological functions</a>  <font color="#6f6f6f">Nature</font>

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Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome
Naturegeneral

Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE1OaEFTN3RvQ1RPQmVuODBFR1QyY25FM3NmcTZNN19VRlpwV1VqVXlCUzA2ZFN0bzRzOU51cHZsU2h5RXNMYVVubF9oeGlMRUtaTVpwc0xrS2dBSVRINldN?oc=5" target="_blank">Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome</a>  <font color="#6f6f6f">Nature</font>

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Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira
Naturegeneral

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTFB6cHFBeld1cEZmemloNy1hdnZQM1UxVGxQRjk3TjZDMDRJbmlRZllJVUVFQmZ2Yi01S0RScXN5U2lXVzYtYUpWTEVSUDczUFNYNE12NGNXYVhRdGlfVXdj?oc=5" target="_blank">Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira</a>  <font color="#6f6f6f">Nature</font>

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Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria
Naturegeneral

Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria

<a href="https://news.google.com/rss/articles/CBMiX0FVX3lxTE5Rd084dVBzT0E5c2pCMDhrT2c4SzVDenRmRXJ2bHppanEwTWhOTEVYWXdLanVXWGQxYTgxYUVXV2pQQ0dxenVEdm1RZ3U1Mmg3WE9GRkFtZ2tQMFR2OFVr?oc=5" target="_blank">Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria</a>  <font color="#6f6f6f">Nature</font>

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X chromosome inactivation unravelled
Natureworld

X chromosome inactivation unravelled

<a href="https://news.google.com/rss/articles/CBMiUEFVX3lxTFBKY3lZTmliQlB3Um1zVWVoN19yaHZwYVJfaWo0TjRmUEFtVlNlRjZ4azB2dEEwVUV0dGt4dnBIMXg0QjhMN2RkbWxLRTg3QVow?oc=5" target="_blank">X chromosome inactivation unravelled</a>  <font color="#6f6f6f">Nature</font>

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Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation
Naturegeneral

Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation

<a href="https://news.google.com/rss/articles/CBMiVEFVX3lxTE1seHhvd3hjYUZMZjRFa1o5UWNJYVloNHRYWnZtQzIySG9iRzV0R1RyZTdORWlRVTVnSFhkN3Vpc2ZiNUVBc0ptZjJXd1JtdWFHcTFOZA?oc=5" target="_blank">Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation</a>  <font color="#6f6f6f">Nature</font>

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The mystery of the human genome's dark matter
BBCgeneral

The mystery of the human genome's dark matter

<a href="https://news.google.com/rss/articles/CBMikgFBVV95cUxQUDUxTUtac2Y0MXZGTElRU1lrSjVPSWR2WXdOc0lGSGJmYXRYcEFTSDl3YWhkeWVWeTMtZjlJVnB3TF9aNVU1em4wUjAxSWw5Wi1nc3RlaVA0NWdSQVBZWmNDVXJOMmZFcjlhaGlCTXYtdkg3d3RhVDlWUU5YRGhndXZscEpmcThlbVlWZHk3SGs2UQ?oc=5" target="_blank">The mystery of the human genome's dark matter</a>  <font color="#6f6f6f">BBC</font>

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